{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T03:44:27Z","timestamp":1788320667312,"version":"build-2803163510"},"reference-count":24,"publisher":"Stanford University Press","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T00:00:00Z","timestamp":1701302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007172","name":"Cincinnati Children's Hospital Medical Center","doi-asserted-by":"publisher","award":["2019-0943"],"award-info":[{"award-number":["2019-0943"]}],"id":[{"id":"10.13039\/100007172","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Mass Spectrometry and Advances in the Clinical Lab"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.jmsacl.2023.11.004","type":"journal-article","created":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T19:11:57Z","timestamp":1701544317000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Use of volumetric absorptive microsampling and parallel reaction monitoring mass spectrometry for tacrolimus blood trough measurements at home in pediatric heart transplant patients"],"prefix":"10.21627","volume":"31","author":[{"given":"Junfang","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth D.R.","family":"Setchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4156-3294","authenticated-orcid":false,"given":"Xueheng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Galandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BreAnn N","family":"Garr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqian","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5168-456X","authenticated-orcid":false,"given":"Clifford","family":"Chin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelly","family":"Stark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Steele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4237-576X","authenticated-orcid":false,"given":"Thomas D.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4811","reference":[{"key":"10.1016\/j.jmsacl.2023.11.004_b0005","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s13318-019-00553-z","article-title":"Predictability of capillary blood spot toward venous whole blood sampling for therapeutic drug monitoring of tacrolimus in solid organ transplant recipients","volume":"44","author":"Gallant","year":"2019","journal-title":"Eur. J. Drug Metab. Pharmacokinet."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2020.461731","article-title":"A review of recent advances in microsampling techniques of biological fluids for therapeutic drug monitoring","volume":"1635","author":"Tey","year":"2021","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jmsacl.2023.11.004_b0015","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s10544-019-0412-y","article-title":"A review of microsampling techniques and their social impact","volume":"21","author":"Lei","year":"2019","journal-title":"Biomed. Microdevices"},{"key":"10.1016\/j.jmsacl.2023.11.004_b0020","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1515\/cclm-2019-1260","article-title":"Volumetric absorptive microsampling and dried blood spot microsampling vs. conventional venous sampling for tacrolimus trough concentration monitoring","volume":"58","author":"Veenhof","year":"2020","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0025","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1093\/jalm\/jfaa005","article-title":"Volumetric microsampling of capillary blood spot vs whole blood sampling for therapeutic drug monitoring of tacrolimus and cyclosporin a: accuracy and patient satisfaction","volume":"5","author":"Mbughuni","year":"2020","journal-title":"J. Appl. Lab. Med."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0030","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/FTD.0000000000000873","article-title":"Tacrolimus measured in capillary volumetric microsamples in pediatric patients-a cross-validation study","volume":"43","author":"Kindem","year":"2021","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0035","doi-asserted-by":"crossref","first-page":"28566","DOI":"10.3390\/ijms161226120","article-title":"Parallel reaction monitoring: a targeted experiment performed using high resolution and high mass accuracy mass spectrometry","volume":"16","author":"Rauniyar","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0040","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1002\/pmic.201500543","article-title":"Parallel reaction monitoring using quadrupole-Orbitrap mass spectrometer: principle and applications","volume":"16","author":"Bourmaud","year":"2016","journal-title":"Proteomics"},{"key":"10.1016\/j.jmsacl.2023.11.004_b0045","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1074\/mcp.O112.020131","article-title":"Parallel reaction monitoring for high resolution and high mass accuracy quantitative, targeted proteomics","volume":"11","author":"Peterson","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.jmsacl.2023.11.004_b0050","unstructured":"F.a.D. Administration, Bioanalytical Method Validation Guidance for Industry, 2018."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0055","doi-asserted-by":"crossref","first-page":"49","DOI":"10.11613\/BM.2011.010","article-title":"Comparison of methods: Passing and Bablok regression","volume":"21","author":"Bilic-Zulle","year":"2011","journal-title":"Biochem Med (zagreb)"},{"key":"10.1016\/j.jmsacl.2023.11.004_b0060","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/096228029900800204","article-title":"Measuring agreement in method comparison studies","volume":"8","author":"Bland","year":"1999","journal-title":"Stat. Methods Med. Res."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0065","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/FTD.0000000000000833","article-title":"Quantitation of tacrolimus in human whole blood samples using the MITRA microsampling device","volume":"43","author":"Undre","year":"2021","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0070","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1097\/FTD.0000000000000847","article-title":"Validation of a capillary dry blood sample MITRA-based assay for the quantitative determination of systemic tacrolimus concentrations in transplant recipients","volume":"43","author":"Undre","year":"2021","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchromb.2020.122521","article-title":"Volumetric absorptive microsampling for the quantification of tacrolimus in capillary blood by high performance liquid chromatography-tandem mass spectrometry","volume":"1165","author":"Tron","year":"2021","journal-title":"J. Chromatogr. B Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0080","doi-asserted-by":"crossref","first-page":"495","DOI":"10.4155\/bio-2018-0312","article-title":"A volumetric absorptive microsampling LC-MS\/MS method for five immunosuppressants and their hematocrit effects","volume":"11","author":"Koster","year":"2019","journal-title":"Bioanalysis"},{"key":"10.1016\/j.jmsacl.2023.11.004_b0085","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1177\/0004563220948886","article-title":"Assessment of tacrolimus and creatinine concentration collected using Mitra microsampling devices","volume":"57","author":"Marshall","year":"2020","journal-title":"Ann. Clin. Biochem."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0090","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1097\/FTD.0000000000000655","article-title":"Tacrolimus can be reliably measured with volumetric absorptive capillary microsampling throughout the dose interval in renal transplant recipients","volume":"41","author":"Vethe","year":"2019","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0095","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics15010299","article-title":"Therapeutic drug monitoring of tacrolimus based on volumetric absorptive microsampling technique (VAMS) in renal transplant pediatric recipients-LC-MS\/MS method development, hematocrit effect evaluation, and clinical application","volume":"15","author":"Kocur","year":"2023","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jmsacl.2023.11.004_b0100","doi-asserted-by":"crossref","first-page":"4854","DOI":"10.1111\/bcp.15433","article-title":"Volumetric microsampling for simultaneous remote immunosuppressant and kidney function monitoring in outpatient kidney transplant recipients","volume":"88","author":"Zwart","year":"2022","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0105","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/FTD.0000000000001024","article-title":"Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients","volume":"45","author":"Scuderi","year":"2023","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0110","doi-asserted-by":"crossref","first-page":"e62","DOI":"10.1093\/labmed\/lmx056","article-title":"Tacrolimus: a review of laboratory detection methods and indications for use","volume":"48","author":"Kalt","year":"2017","journal-title":"Lab. Med."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0115","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1373\/clinchem.2013.220012","article-title":"Tacrolimus measurement: building a better immunoassay","volume":"60","author":"Gounden","year":"2014","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jmsacl.2023.11.004_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113102","article-title":"Opportunities and obstacles for microsampling techniques in bioanalysis: Special focus on DBS and VAMS","volume":"182","author":"Londhe","year":"2020","journal-title":"J. Pharm. Biomed. Anal."}],"container-title":["Journal of Mass Spectrometry and Advances in the Clinical Lab"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667145X2300038X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667145X2300038X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T07:22:40Z","timestamp":1767770560000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667145X2300038X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":24,"alternative-id":["S2667145X2300038X"],"URL":"https:\/\/doi.org\/10.1016\/j.jmsacl.2023.11.004","relation":{},"ISSN":["2667-145X"],"issn-type":[{"value":"2667-145X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Use of volumetric absorptive microsampling and parallel reaction monitoring mass spectrometry for tacrolimus blood trough measurements at home in pediatric heart transplant patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Mass Spectrometry and Advances in the Clinical Lab","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmsacl.2023.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 THE AUTHORS. Publishing services by ELSEVIER B.V. on behalf of MSACL.","name":"copyright","label":"Copyright"}]}}