{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:10:23Z","timestamp":1759972223080,"version":"build-2065373602"},"reference-count":51,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal des Maladies Vasculaires"],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1016\/j.jmv.2007.03.001","type":"journal-article","created":{"date-parts":[[2012,2,24]],"date-time":"2012-02-24T07:45:07Z","timestamp":1330069507000},"page":"75-82","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Les microangiopathies thrombotiques. Incidence, physiopathologie, tableau clinique, prise en\u00a0charge th\u00e9rapeutique et\u00a0pronostic"],"prefix":"10.1016","volume":"32","author":[{"given":"M.","family":"Bahloul","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Dammak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Kallel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Khlaf-Bouaziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ben Hamida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Chaari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Chelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Rekik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bouaziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmv.2007.03.001_bib1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1056\/NEJMra020528","article-title":"Thrombotic microangiopathies","volume":"347","author":"Moake","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib2","first-page":"294","article-title":"An acute febrile pleiochromic anemia with hyaline thrombosis of the terminal arterioles and capillaries: an undescribed disease","volume":"36","author":"Moschowitz","year":"1925","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00134-004-2505-0","article-title":"Outcome of severe adult thrombotic microangiopathies in the intensive care unit","volume":"31","author":"Pene","year":"2005","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib4","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1007\/s00134-003-1676-4","article-title":"Infectious diseases as a trigger in thrombotic microangiopathies in intensive care unit (ICU) patients?","volume":"29","author":"Coppo","year":"2003","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib5","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.annfar.2006.04.012","article-title":"Les microangiopathies thrombotiques en r\u00e9animation","volume":"25","author":"Bahloul","year":"2006","journal-title":"Ann. Fr. Anesth. Reanim."},{"key":"10.1016\/j.jmv.2007.03.001_bib6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/01.SMJ.0000136231.83564.F6","article-title":"Thrombotic thrombocytopenic purpura without schistocytes on the peripheral blood smear","volume":"98","author":"Daram","year":"2005","journal-title":"South. Med. J."},{"key":"10.1016\/j.jmv.2007.03.001_bib7","doi-asserted-by":"crossref","unstructured":"Coppo P, Vernant J-P, Veyradier A, Fr\u00e9meaux-Bacchi V, Mira J-P, Guidet B, et al. Purpura thrombotique et autres syndromes de microangiopathie thrombotique. Encycl. M\u00e9d. Chir. (Elsevier, Paris). H\u00e9matologie. 2005;2:14\u201334.","DOI":"10.1016\/j.emch.2004.12.002"},{"issue":"Suppl 4","key":"10.1016\/j.jmv.2007.03.001_bib8","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S0929-693X(01)80196-2","article-title":"Syndrome h\u00e9molytique et ur\u00e9mique typique post-diarrh\u00e9e: aspects cliniques","volume":"8","author":"Loirat","year":"2001","journal-title":"Arch. Pediatr."},{"key":"10.1016\/j.jmv.2007.03.001_bib9","doi-asserted-by":"crossref","first-page":"698","DOI":"10.7326\/0003-4819-123-9-199511010-00009","article-title":"Escherichia coli O157: H7 infection in humans","volume":"123","author":"Su","year":"1995","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib10","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0953-6205(00)00083-2","article-title":"Thrombotic microangiopathy","volume":"11","author":"Pisoni","year":"2000","journal-title":"Eur. J. Intern. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1182\/blood-2004-10-4097","article-title":"ADAMTS13 turns 3","volume":"106","author":"Levy","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.jmv.2007.03.001_bib12","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1056\/NEJM199811263392202","article-title":"Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome","volume":"339","author":"Furlan","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib13","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0248-8663(00)00223-X","article-title":"Le purpura thrombotique thrombocytop\u00e9nique idiopathique ou syndrome de Moschowitz: actualit\u00e9s physiopathologiques et perspectives th\u00e9rapeutiques","volume":"21","author":"Retornaz","year":"2000","journal-title":"Rev. Med. Interne"},{"key":"10.1016\/j.jmv.2007.03.001_bib14","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1182\/blood.V80.8.1890.bloodjournal8081890","article-title":"Thrombotic microangiopathies in the 1980s: clinical features, response to treatment, and the impact of the human immunodeficiency virus epidemic","volume":"80","author":"Thompson","year":"1992","journal-title":"Blood"},{"key":"10.1016\/j.jmv.2007.03.001_bib15","doi-asserted-by":"crossref","first-page":"834","DOI":"10.5858\/2003-127-834-TTPAHU","article-title":"Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome are distinct pathologic entities. A review of 56 autopsy cases","volume":"127","author":"Hosler","year":"2003","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib16","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S1624-0693(02)00253-0","article-title":"Le purpura thrombotique thrombocytop\u00e9nique: physiopathologie et traitement","volume":"11","author":"Retornaz","year":"2002","journal-title":"R\u00e9animation"},{"key":"10.1016\/j.jmv.2007.03.001_bib17","first-page":"300","article-title":"Pathophysiology and management of thrombotic microangiopathies","volume":"11","author":"Ruggenenti","year":"1998","journal-title":"J. Nephrol."},{"key":"10.1016\/j.jmv.2007.03.001_bib18","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1182\/blood.V98.6.1765","article-title":"Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: a study of 111 cases","volume":"98","author":"Veyradier","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.jmv.2007.03.001_bib19","first-page":"94","article-title":"The changing course of thrombotic thrombocytopenic purpura and modern therapy","volume":"7","author":"Rose","year":"1993","journal-title":"Blood"},{"key":"10.1016\/j.jmv.2007.03.001_bib20","first-page":"662","article-title":"The long-term consequences of thrombotic microangiopathy (thrombotic thrombocytopenic purpura and hemolytic uremic syndrome) in pregnancy","volume":"91","author":"Dashe","year":"1998","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jmv.2007.03.001_bib21","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0140-6736(03)15309-3","article-title":"Coagulation, iflammation and pregnancy complications","volume":"363","author":"Sarig","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jmv.2007.03.001_bib22","first-page":"1029","article-title":"Mild to moderate reduction of a von Willebrand factor cleaving protease (ADAMTS-13) in pregnant women with HELLP microangiopathic syndrome","volume":"88","author":"Lattuada","year":"2003","journal-title":"Haematologica"},{"key":"10.1016\/j.jmv.2007.03.001_bib23","first-page":"520","article-title":"Thrombotic thrombocytopenic purpura, systemic lupus erythematosus and rescue treatment with cyclophosphamide","volume":"205","author":"Ramirez Duque","year":"2005","journal-title":"Rev. Clin. Esp."},{"key":"10.1016\/j.jmv.2007.03.001_bib24","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/01.md.0000133622.03370.07","article-title":"Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count and mild renal involvement","volume":"83","author":"Coppo","year":"2004","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jmv.2007.03.001_bib25","first-page":"49","article-title":"Hemolytic-uremic syndrome secondary to scorpion envenomation (apropos of 2 cases)","volume":"25","author":"Bahloul","year":"2004","journal-title":"Nephrologie"},{"key":"10.1016\/j.jmv.2007.03.001_bib26","first-page":"416","article-title":"Plasma exchanges and replacement fluids for adult thrombotic microangiopathy. Synopsis of the round table held on May 3, 2001","volume":"153","author":"Courtois","year":"2002","journal-title":"Ann. Med. Interne (Paris)"},{"key":"10.1016\/j.jmv.2007.03.001_bib27","first-page":"19","article-title":"Plasma manipulation in hemolytic uremic syndrome and thrombotic thrombocytopenic purpura","volume":"143","author":"Remuzzi","year":"1992","journal-title":"Ann. Med. Interne (Paris)"},{"key":"10.1016\/j.jmv.2007.03.001_bib28","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00005792-200301000-00003","article-title":"High dose plasma infusion versus plasma exchange as early treatment of thrombotic thrombocytopenic purpura\/haemolytic-uremic syndrome","volume":"82","author":"Coppo","year":"2003","journal-title":"Medicine"},{"key":"10.1016\/j.jmv.2007.03.001_bib29","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1046\/j.1365-2141.2000.01941.x","article-title":"Management of thrombotic thrombocytopenic purpura","volume":"109","author":"Rock","year":"2000","journal-title":"Br J Hematol"},{"key":"10.1016\/j.jmv.2007.03.001_bib30","series-title":"Sfar, Eds. Conf\u00e9rences d'actualisation. 39e Congr\u00e8s national d\u2019anesth\u00e9sie et de r\u00e9animation","first-page":"533","article-title":"\u00c9changes plasmatiques en r\u00e9animation","author":"Guidet","year":"1996"},{"key":"10.1016\/j.jmv.2007.03.001_bib31","first-page":"346","article-title":"Thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome in adults. Apropos of 27 cases","volume":"148","author":"Hamdini","year":"1997","journal-title":"Ann. Med. Interne (Paris)"},{"key":"10.1016\/j.jmv.2007.03.001_bib32","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1001\/jama.1981.03320170043028","article-title":"Hazard of platelet transfusion in thrombotic thrombocytopenic purpura","volume":"246","author":"Harkness","year":"1981","journal-title":"JAMA"},{"key":"10.1016\/j.jmv.2007.03.001_bib33","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1055\/s-2007-1005066","article-title":"Thrombotic thrombocytopenic purpura: experience with whole blood exchange transfusion","volume":"7","author":"Gottschall","year":"1981","journal-title":"Semin. Thromb. Hemost."},{"key":"10.1016\/j.jmv.2007.03.001_bib34","first-page":"194","article-title":"Deleterious effects of platelet transfusions and recovery thrombocytosis in patients with thrombotic microangiopathy","volume":"24","author":"Gordon","year":"1987","journal-title":"Semin. Hematol."},{"issue":"Suppl 1","key":"10.1016\/j.jmv.2007.03.001_bib35","first-page":"669a","article-title":"Do platelet transfusions to patients with TTP influence their survival?","volume":"84","author":"Mac Carthy","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.jmv.2007.03.001_bib36","first-page":"16973","article-title":"Has heparin changed the prognosis of the hemolytic-uremic syndrome","volume":"5","author":"Proesmans","year":"1974","journal-title":"Clin. Neprol."},{"key":"10.1016\/j.jmv.2007.03.001_bib37","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0022-3476(73)80490-1","article-title":"Heparin therapy in the hemolytic-uremic syndrome","volume":"83","author":"Vittaco","year":"1973","journal-title":"J. Pedriatr."},{"key":"10.1016\/j.jmv.2007.03.001_bib38","first-page":"15","article-title":"Traitement du syndrome h\u00e9molytique et ur\u00e9mique de l'enfant par l'urokinase: essai contr\u00f4le coop\u00e9ratif","volume":"41","author":"Loirat","year":"1984","journal-title":"Arch. Fr. Pediatr."},{"key":"10.1016\/j.jmv.2007.03.001_bib39","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0022-3476(88)80031-3","article-title":"Heparin plus dipyridamole in childhood hemolyticuremic syndrome: a prospective, randomized study","volume":"113","author":"Van Damme-Lombaerts","year":"1988","journal-title":"J. Pediatr."},{"key":"10.1016\/j.jmv.2007.03.001_bib40","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1056\/NEJM199108083250605","article-title":"Improved survival in thrombotic thrombocytopenic purpura hemolytic uremic syndrome: clinical experience in 108 patients","volume":"325","author":"Bell","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib41","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1159\/000188231","article-title":"Renal microangiopathy in the primary antiphospholipid syndrome: a case report with literature review","volume":"68","author":"Domrongkitchaiporn","year":"1994","journal-title":"Nephron"},{"key":"10.1016\/j.jmv.2007.03.001_bib42","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0002-9343(99)00286-7","article-title":"Improved survival with plasma exchange in patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome","volume":"107","author":"Lara","year":"1999","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib43","doi-asserted-by":"crossref","first-page":"4023","DOI":"10.1182\/blood-2003-11-4035","article-title":"Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura","volume":"103","author":"Zheng","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.jmv.2007.03.001_bib44","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0002-9343(87)90753-4","article-title":"High incidence of relapses in thrombotic thrombocytopenic purpura. Clinical study of 38 patients","volume":"83","author":"Rose","year":"1987","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jmv.2007.03.001_bib45","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1182\/blood.V96.4.1223","article-title":"How I treat patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome","volume":"96","author":"George","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.jmv.2007.03.001_bib46","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1182\/asheducation-2004.1.407","article-title":"Recent advances in thrombotic thrombocytopenic purpura","author":"Sadler","year":"2004","journal-title":"Hematology (Am. Soc. Hematol. Educ. Program)"},{"key":"10.1016\/j.jmv.2007.03.001_bib47","first-page":"482","article-title":"Spotlight on rituximab as a new therapeutic option for dermatomyositis and thrombotic thrombocytopenic purpura","volume":"19","author":"Ferrer","year":"2006","journal-title":"Drug News Perspect."},{"key":"10.1016\/j.jmv.2007.03.001_bib48","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1111\/j.1537-2995.2006.00959.x","article-title":"A randomized, controlled Phase III trial of therapeutic plasma exchange with fresh-frozen plasma (FFP) prepared with amotosalen and ultraviolet A light compared to untreated FFP in thrombotic thrombocytopenic purpura","volume":"46","author":"Mintz","year":"2006","journal-title":"Transfusion"},{"key":"10.1016\/j.jmv.2007.03.001_bib49","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1097\/01.moh.0000170534.33517.99","article-title":"Immunotherapy for thrombotic thrombocytopenic purpura","volume":"12","author":"Cataland","year":"2005","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.jmv.2007.03.001_bib50","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1111\/j.1538-7836.2006.02164.x","article-title":"Multiple B-cell clones producing antibodies directed to the spacer and disintegrin\/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura","volume":"4","author":"Luken","year":"2006","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.jmv.2007.03.001_bib51","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1160\/TH06-06-0317","article-title":"The efficacy of rituximab in the treatment of inhibitor-associated hemostatic disorders","volume":"96","author":"Franchini","year":"2006","journal-title":"Thromb. Haemost."}],"container-title":["Journal des Maladies Vasculaires"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0398049907001874?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0398049907001874?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T20:10:27Z","timestamp":1759954227000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0398049907001874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["S0398049907001874"],"URL":"https:\/\/doi.org\/10.1016\/j.jmv.2007.03.001","relation":{},"ISSN":["0398-0499"],"issn-type":[{"type":"print","value":"0398-0499"}],"subject":[],"published":{"date-parts":[[2007,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Les microangiopathies thrombotiques. Incidence, physiopathologie, tableau clinique, prise en\u00a0charge th\u00e9rapeutique et\u00a0pronostic","name":"articletitle","label":"Article Title"},{"value":"Journal des Maladies Vasculaires","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmv.2007.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}