{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T12:20:51Z","timestamp":1785241251662,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,12,24]],"date-time":"2010-12-24T00:00:00Z","timestamp":1293148800000},"content-version":"vor","delay-in-days":2360,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Midwife Womens Health"],"published-print":{"date-parts":[[2004,7,8]]},"abstract":"<jats:p>Nausea and vomiting of pregnancy (NVP) affects up to 80% of all women to some degree during their pregnancies. Diclectin (doxy lamine and pyridoxine [vitamin B6]) has been on the Canadian market for many years and is indicated as the drug of choice for the treatment of NVP. However, some women choose not to treat NVP with pharmacologic measures, perhaps due to a persistent fear of teratogenic risk. The objective of this study was to determine the factors that influence a woman's decision not to treat NVP with pharmacologic measures. Fifty\u2010nine women recruited from the Motherisk Nausea and Vomiting Helpline completed a questionnaire. All were informed that Diclectin was considered safe for use during pregnancy. At a follow\u2010up telephone call, 34% were not using any pharmacologic treatment, and of those who were taking the drug, 26% were using less than the recommended dose. Reasons cited for not using the medication were insufficient safety data, preference for non\u2010pharmacologic methods, and being made to feel uncomfortable by the physician. Of the women who did use Diclectin, the most convincing reassuring information that it was safe to use came from friends and family. Many other factors play a large role in a women's decision making.<\/jats:p>","DOI":"10.1016\/j.jmwh.2004.03.011","type":"journal-article","created":{"date-parts":[[2004,8,25]],"date-time":"2004-08-25T15:32:18Z","timestamp":1093447938000},"page":"350-354","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Determinants of Women's Decision Making on Whether to Treat Nausea and Vomiting of Pregnancy Pharmacologically"],"prefix":"10.1111","volume":"49","author":[{"given":"Anne","family":"Baggley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvette","family":"Navioz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Maltepe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gideon","family":"Koren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrienne","family":"Einarson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,24]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(02)00070-5"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70349-8"},{"key":"e_1_2_6_4_2","first-page":"302","article-title":"Isolation from \u201cbeing alive:\u201d Coping with severe nausea and vomiting of pregnancy","volume":"51","author":"O'Brien B","year":"2002","journal-title":"Nurs Res"},{"key":"e_1_2_6_5_2","first-page":"245","article-title":"A prospective study of nausea and vomiting during pregnancy","volume":"43","author":"Gadsby R","year":"1993","journal-title":"Br J Gen Pract"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/01674820009075620"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.122605"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.3109\/01674820109049946"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-9424"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.122603"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-536X.1992.tb00671.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000145"},{"key":"e_1_2_6_13_2","first-page":"33","article-title":"Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: A randomized, double\u2010blind placebo\u2010controlled study","volume":"78","author":"Sahakian V","year":"1991","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(91)90202-V"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01228-X"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00649-5"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/106002808802201021"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0890-6238(94)00050-7"},{"key":"e_1_2_6_19_2","unstructured":"Diclectin Product Monograph. Duchesnay Inc. Laval Quebec Canada 2003. Compendium of Pharmaceuticals and Specialties (CPS)."},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/00912700122010735"},{"key":"e_1_2_6_21_2","first-page":"205","article-title":"Longitudinal change in the treatment of nausea and vomiting of pregnancy in Ontario","volume":"7","author":"Lee J","year":"2000","journal-title":"Can J Clin Pharmacol"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.122601"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-2-5"},{"key":"e_1_2_6_24_2","article-title":"Clinical practice guidelines for the management of nausea and vomiting of pregnancy","author":"SOGC","year":"1995","journal-title":"The Society of Obstetricians and Gynecologists of Canada"},{"key":"e_1_2_6_25_2","unstructured":"BonariL EinarsonAJasperJD EinarsonTR KorenG.Determinants of women' s decision making regarding the use of anti\u2010depressants during pregnancy (abstract). 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