{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T23:11:39Z","timestamp":1778109099424,"version":"3.51.4"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2004,4]]},"DOI":"10.1016\/j.jneumeth.2003.11.018","type":"journal-article","created":{"date-parts":[[2004,1,23]],"date-time":"2004-01-23T05:18:16Z","timestamp":1074835096000},"page":"121-131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Capacitance measurements at the calyx of Held in the medial nucleus of the trapezoid body"],"prefix":"10.1016","volume":"134","author":[{"given":"Jian-Yuan","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin-Sheng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan-Xue","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Dondzillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-Gang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2003.11.018_BIB1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0166-2236(97)01083-7","article-title":"Monitoring secretion in real time: capacitance, amperometry and fluorescence compared","volume":"20","author":"Angleson","year":"1997","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB2","doi-asserted-by":"crossref","first-page":"8328","DOI":"10.1073\/pnas.92.18.8328","article-title":"Rapic endocytosis coupled to exocytosis in adrenal chromaffin cells involves Ca2+, GTP, and dynamin but not clathrin","volume":"92","author":"Artalejo","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB3","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1113\/jphysiol.1992.sp019126","article-title":"Calcium requirements for secretion in bovine chromaffin cells","volume":"450","author":"Augustine","year":"1992","journal-title":"J. Physiol."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB4","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0896-6273(01)00243-4","article-title":"Calcium dependence of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse","volume":"29","author":"Beutner","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB5","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1113\/jphysiol.1995.sp021095","article-title":"Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapezoid body of the rat","volume":"489","author":"Borst","year":"1995","journal-title":"J. Physiol."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB6","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1469-7793.1998.143bx.x","article-title":"Calcium current during a single action potential in a large presynaptic terminal of the rat brainstem","volume":"506","author":"Borst","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB7","doi-asserted-by":"crossref","unstructured":"Gillis KD. Techniques for membrane capacitance measurements. In: Sakmann B, Neher E, editors. Single-channel recording. New York: Plenum Press; 1995. p. 155\u201398.","DOI":"10.1007\/978-1-4419-1229-9_7"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB8","doi-asserted-by":"crossref","first-page":"8975","DOI":"10.1073\/pnas.1432836100","article-title":"A large pool of releasable vesicles in a cortical glutamatergic synapse","volume":"100","author":"Hallermann","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB9","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/371513a0","article-title":"Calcium dependence of the rate of exocytosis in a synaptic terminal","volume":"371","author":"Heidelberger","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB10","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/0896-6273(94)90050-7","article-title":"Releasable pools and the kinetics of exocytosis in adrenal chromaffin cells","volume":"13","author":"Horrigan","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB11","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1113\/jphysiol.1996.sp021512","article-title":"Rapid exocytosis and endocytosis in nerve terminals of the rat posterior pituitary","volume":"492","author":"Hsu","year":"1996","journal-title":"J. Physiol."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB12","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/S0006-3495(92)81880-5","article-title":"Cable analysis with the whole-cell patch clamp. Theory and experiment","volume":"61","author":"Jackson","year":"1992","journal-title":"Biophys. J."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB13","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF00582306","article-title":"Patch-clamp techniques for time-resolved capacitance measurements in single cells","volume":"411","author":"Lindau","year":"1988","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB14","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1152\/jn.1997.78.1.51","article-title":"Static and dynamic membrane properties of large-terminal bipolar cells from goldfish retina: experimental test of a compartment model","volume":"78","author":"Mennerick","year":"1997","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB15","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/0896-6273(95)90097-7","article-title":"Docked granules, the exocytic burst, and the need for ATP hydrolysis in endocrine cells","volume":"15","author":"Parsons","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB16","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/0896-6273(94)90253-4","article-title":"Calcium-triggered exocytosis and endocytosis in an isolated presynaptic cell: capacitance measurements in saccular hair cells","volume":"13","author":"Parsons","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1996.sp021360","article-title":"Asynchronous transmitter release: control of exocytosis and endocytosis at the salamander rod synapse","volume":"493","author":"Rieke","year":"1996","journal-title":"J. Physiol."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB18","first-page":"10","article-title":"Measurements of vesicle recycling in central neurons","volume":"16","author":"Ryan","year":"2001","journal-title":"News Physiol. Sci."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0896-6273(01)00271-9","article-title":"Fast kinetics of exocytosis revealed by simultaneous measurements of presynaptic capacitance and postsynaptic currents at a central synapse","volume":"30","author":"Sun","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB20","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/417555a","article-title":"Single and multiple vesicle fusion induce different rates of endocytosis at a central synapse","volume":"417","author":"Sun","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB21","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/S0896-6273(02)01137-6","article-title":"Optimizing synaptic architecture and efficiency for high-frequency transmission","volume":"36","author":"Taschenberger","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB22","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/367735a0","article-title":"Dynamics of synaptic vesicle fusion and membrane retrieval in synaptic terminals","volume":"367","author":"Von Gersdorff","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB23","doi-asserted-by":"crossref","first-page":"7059","DOI":"10.1523\/JNEUROSCI.23-18-07059.2003","article-title":"Presynaptic capacitance measurements and Ca2+ uncaging reveal submillisecond exocytosis kinetics and characterize the Ca2+ sensitivity of vesicle pool depletion at a fast CNS synapse","volume":"23","author":"W\u00f6lfel","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB24","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1073\/pnas.95.8.4720","article-title":"R-type Ca2+ currents evoke transmitter release at a rat central synapse","volume":"95","author":"Wu","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB25","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1523\/JNEUROSCI.19-02-00726.1999","article-title":"Calcium channel types with distinct presynaptic localization couple differentially to transmitter release in single calyx-type synapses","volume":"19","author":"Wu","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB26","doi-asserted-by":"crossref","first-page":"7928","DOI":"10.1523\/JNEUROSCI.21-20-07928.2001","article-title":"Protein kinase C increases the apparent affinity of the release machinery to Ca2+ by enhancing the release machinery downstream of the Ca2+ sensor","volume":"21","author":"Wu","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2003.11.018_BIB27","unstructured":"Zar JH. Biostatistical analysis. 2nd ed. Englewood Cliffs, NJ: Prentice-Hall; 1984."}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027003003856?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027003003856?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:03:35Z","timestamp":1759017815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027003003856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,4]]}},"alternative-id":["S0165027003003856"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2003.11.018","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2004,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Capacitance measurements at the calyx of Held in the medial nucleus of the trapezoid body","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2003.11.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}