{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:26:25Z","timestamp":1791293185000,"version":"4.1.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T00:00:00Z","timestamp":1149120000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T00:00:00Z","timestamp":1149120000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1016\/j.jneumeth.2005.12.002","type":"journal-article","created":{"date-parts":[[2006,1,27]],"date-time":"2006-01-27T09:54:49Z","timestamp":1138355689000},"page":"89-95","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Breeding and maintenance of an Mecp2-deficient mouse model of Rett syndrome"],"prefix":"10.1016","volume":"154","author":[{"given":"Denis G.M.","family":"Jugloff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Logan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James H.","family":"Eubanks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2005.12.002_bib1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/13810","article-title":"Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2","volume":"23","author":"Amir","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib2","doi-asserted-by":"crossref","unstructured":"Asaka Y, Jugloff DG, Zhang L, Eubanks JH, Fitzsimonds RM. Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol Dis 2006;21:217\u201327.","DOI":"10.1016\/j.nbd.2005.07.005"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib3","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1093\/hmg\/ddh142","article-title":"X-Chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2\u2212\/+ mouse brain","volume":"13","author":"Braunschweig","year":"2004","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib4","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/85906","article-title":"Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice","volume":"27","author":"Chen","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib5","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/85899","article-title":"A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome","volume":"27","author":"Guy","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib6","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/ana.410140412","article-title":"A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases","volume":"14","author":"Hagberg","year":"1983","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib7","first-page":"482","article-title":"Effects of sunflower seed supplements on reproduction and growth of RCS rats with hereditary retinal dystrophy","volume":"31","author":"Hess","year":"1981","journal-title":"Lab Anim Sci"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib8","series-title":"Rett disorder and the developing brain","article-title":"The clinical background to rett disorder","author":"Kerr","year":"2001"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib9","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.mcn.2004.07.006","article-title":"MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions","volume":"27","author":"Kishi","year":"2004","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib10","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1093\/hmg\/ddi097","article-title":"MeCP2 deficiency in Rett syndrome causes epigenetic aberrations at the PWS\/AS imprinting center that affects UBE3A expression","volume":"14","author":"Makedonski","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib11","unstructured":"Nag N, Yang RJ, Berger-Sweeney JE. The effects of dietary perinatal choline supplementation on the behavioral phenotype of Mecp2 mutant mice. Program No. 1011.8. 2005 Abstract Viewer\/Itinerary Planner. Washington, DC: Society for Neuroscience; 2005 [online]."},{"key":"10.1016\/j.jneumeth.2005.12.002_bib12","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/S0733-8619(02)00022-1","article-title":"Rett syndrome. Current status and new vistas","volume":"20","author":"Percy","year":"2002","journal-title":"Neurol Clin"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib13","first-page":"723","article-title":"On an unusual brain atrophy syndrome in hyperammonemia in childhood","volume":"116","author":"Rett","year":"1966","journal-title":"Wien Med Wochenschr"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib14","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1093\/hmg\/ddi045","article-title":"Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3","volume":"14","author":"Samaco","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib15","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0896-6273(02)00768-7","article-title":"Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3","volume":"35","author":"Shahbazian","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib16","doi-asserted-by":"crossref","first-page":"15536","DOI":"10.1073\/pnas.242566899","article-title":"Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain","volume":"99","author":"Tudor","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jneumeth.2005.12.002_bib17","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1086\/382228","article-title":"X-chromosome inactivation patterns are unbalanced and affect the phenotypic outcome in a mouse model of Rett syndrome","volume":"74","author":"Young","year":"2004","journal-title":"Am J Hum Genet"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027005004504?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027005004504?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:09:16Z","timestamp":1759018156000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027005004504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6]]},"references-count":17,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["S0165027005004504"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2005.12.002","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2006,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Breeding and maintenance of an Mecp2-deficient mouse model of Rett syndrome","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2005.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}