{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T11:20:41Z","timestamp":1772882441953,"version":"3.50.1"},"reference-count":66,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.jneumeth.2007.01.018","type":"journal-article","created":{"date-parts":[[2007,2,3]],"date-time":"2007-02-03T02:46:44Z","timestamp":1170470804000},"page":"244-254","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Characterization of a thromboembolic photochemical model of repeated stroke in mice"],"prefix":"10.1016","volume":"162","author":[{"given":"J. Diego","family":"Lozano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise P.","family":"Abulafia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary H.","family":"Danton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brant D.","family":"Watson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. Dalton","family":"Dietrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2007.01.018_bib1","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1097\/00004647-200012000-00007","article-title":"Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94","volume":"20","author":"Asahi","year":"2000","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib2","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0006-8993(00)03331-X","article-title":"Further characterisation of a thromboembolic model of stroke in the rat","volume":"895","author":"Beech","year":"2001","journal-title":"Brain Res"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib3","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0006-8993(99)01528-0","article-title":"Middle cerebral artery occlusion in the mouse by intraluminal suture coated with poly-l-lysine: neurological and histological validation","volume":"833","author":"Belayev","year":"1999","journal-title":"Brain Res"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib4","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/37635","article-title":"Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2","volume":"390","author":"Bonventre","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib5","doi-asserted-by":"crossref","first-page":"5528","DOI":"10.1523\/JNEUROSCI.21-15-05528.2001","article-title":"Role of IL-1alpha and IL-1beta in ischemic brain damage","volume":"21","author":"Boutin","year":"2001","journal-title":"J Neurosci"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib6","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1161\/01.STR.10.1.34","article-title":"Brain edema and blood-brain barrier permeability following quantitative cerebral microembolism","volume":"10","author":"Bralet","year":"1979","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib7","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1602\/neurorx.2.3.396","article-title":"Rodent models of focal stroke: size, mechanism, and purpose","volume":"2","author":"Carmichael","year":"2005","journal-title":"NeuroRx"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib8","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1161\/01.RES.81.3.304","article-title":"Exacerbation of cerebral injury in mice that express the P-selectin gene: identification of P-selectin blockade as a new target for the treatment of stroke","volume":"81","author":"Connolly","year":"1997","journal-title":"Circ Res"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib9","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1097\/00004647-200205000-00013","article-title":"Endothelial nitric oxide synthase pathophysiology after nonocclusive common carotid artery thrombosis in rats","volume":"22","author":"Danton","year":"2002","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib10","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1161\/hs0402.105554","article-title":"Temporal profile of enhanced vulnerability of the postthrombotic brain to secondary embolic events","volume":"33","author":"Danton","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib11","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1161\/01.STR.24.10.1534","article-title":"Transient platelet accumulation in the rat brain after common carotid artery thrombosis. An 111In-labeled platelet study","volume":"24","author":"Dietrich","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib12","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1097\/00005072-199307000-00002","article-title":"Microvascular and neuronal consequences of common carotid artery thrombosis and platelet embolization in rats","volume":"52","author":"Dietrich","year":"1993","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/00005072-198807000-00005","article-title":"Middle cerebral artery thrombosis: acute blood\u2013brain barrier consequences","volume":"47","author":"Dietrich","year":"1988","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib14","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/BF00687262","article-title":"Photochemically induced cerebral infarction. I. Early microvascular alterations","volume":"72","author":"Dietrich","year":"1987","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib15","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1097\/00000542-199806000-00022","article-title":"In vitro hypothermia enhances platelet GPIIb\u2013IIIa activation and P-selectin expression","volume":"88","author":"Faraday","year":"1998","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib16","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1161\/01.STR.0000138730.03264.ac","article-title":"Serum S100B predicts a malignant course of infarction in patients with acute middle cerebral artery occlusion","volume":"35","author":"Foerch","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib17","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/ana.410230307","article-title":"A new model of embolic stroke produced by photochemical injury to the carotid artery in the rat","volume":"23","author":"Futrell","year":"1988","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib18","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0165-0270(02)00322-9","article-title":"The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats","volume":"122","author":"Gerriets","year":"2003","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib19","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1097\/00004647-199609000-00023","article-title":"Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-l-arginine","volume":"16","author":"Huang","year":"1996","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib20","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/00005373-199409000-00014","article-title":"Functional equivalence of hypothermia to specific clotting factor deficiencies","volume":"37","author":"Johnston","year":"1994","journal-title":"J Trauma"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib21","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1161\/01.STR.22.11.1448","article-title":"Platelet secretory products may contribute to neuronal injury","volume":"22","author":"Joseph","year":"1991","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib22","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/01.STR.16.1.76","article-title":"Cerebral infarction in rats using homologous blood emboli: development of a new experimental model","volume":"16","author":"Kaneko","year":"1985","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib23","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1097\/00001756-199809140-00009","article-title":"A reproducible model of thromboembolic stroke in mice","volume":"9","author":"Kilic","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib24","doi-asserted-by":"crossref","first-page":"11158","DOI":"10.1073\/pnas.88.24.11158","article-title":"Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase","volume":"88","author":"Kinouchi","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3995\/jstroke.8.1","article-title":"Experimental studies of ischemic brain edema. I. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area","volume":"8","author":"Koizumi","year":"1986","journal-title":"Jpn J Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib26","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1161\/01.STR.13.4.505","article-title":"An animal model of cerebral infarction. Homologous blood clot emboli in rats","volume":"13","author":"Kudo","year":"1982","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib27","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1179\/016164102101199594","article-title":"Focal cerebral ischemia in rats produced by intracarotid embolization with viscous silicone","volume":"24","author":"Lauer","year":"2002","journal-title":"Neurol Res"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib28","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1159\/000071128","article-title":"Annual incidence of first silent stroke in the United States: a preliminary estimate","volume":"16","author":"Leary","year":"2003","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib29","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1161\/01.STR.27.11.2110","article-title":"Evolution of photochemically induced focal cerebral ischemia in the rat. Magnetic resonance imaging and histology","volume":"27","author":"Lee","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib30","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1161\/01.STR.30.11.2464","article-title":"Spontaneous hyperthermia and its mechanism in the intraluminal suture middle cerebral artery occlusion model of rats","volume":"30","author":"Li","year":"1999","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib31","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.nic.2005.08.012","article-title":"Collaterals in acute stroke: beyond the clot","volume":"15","author":"Liebeskind","year":"2005","journal-title":"Neuroimaging Clin N Am"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib32","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1161\/01.STR.25.12.2421","article-title":"A rapid, reliable, and valid method for measuring infarct and brain compartment volumes from computed tomographic scans","volume":"25","author":"Lyden","year":"1994","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib33","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1097\/00001756-199805110-00012","article-title":"Differences in the cerebrovascular anatomy of C57black\/6 and SV129 mice","volume":"9","author":"Maeda","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib34","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/72256","article-title":"Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke","volume":"6","author":"Manley","year":"2000","journal-title":"Nat Med"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib35","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1161\/01.STR.0000230307.03438.94","article-title":"Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke","volume":"37","author":"Marder","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib36","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1002\/mrm.20100","article-title":"Microsphere-induced embolic stroke: an MRI study","volume":"51","author":"Mayzel-Oreg","year":"2004","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib37","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brainres.2003.10.028","article-title":"Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl\/6J mice","volume":"997","author":"McColl","year":"2004","journal-title":"Brain Res"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib38","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1023\/B:MEBR.0000043966.46964.e6","article-title":"Pathophysiology of stroke: lessons from animal models","volume":"19","author":"Mergenthaler","year":"2004","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib39","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1161\/01.STR.24.3.415","article-title":"Sustained decrease in brain regional blood flow after microsphere embolism in rats","volume":"24","author":"Miyake","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib40","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s11936-004-0021-8","article-title":"Current management of syncope: treatment alternatives","volume":"6","author":"Morillo","year":"2004","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib41","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3109\/15419060109080747","article-title":"A neuroprotective role for gap junctions","volume":"8","author":"Naus","year":"2001","journal-title":"Cell Commun Adhes"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib42","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1161\/01.STR.31.9.2175","article-title":"Prediction of malignant middle cerebral artery infarction by diffusion-weighted imaging","volume":"31","author":"Oppenheim","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib43","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1161\/01.STR.23.8.1167","article-title":"Reduction of infarct volume and mortality by thrombolysis in a rat embolic stroke model","volume":"23","author":"Overgaard","year":"1992","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib44","series-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2001"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib45","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S1056-8719(01)00153-8","article-title":"A photothrombotic model of small early ischemic infarcts in the rat brain with histologic and MRI correlation","volume":"45","author":"Pevsner","year":"2001","journal-title":"J Pharmacol Toxicol Methods"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib46","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1006\/exnr.2000.7367","article-title":"Postischemic spontaneous hyperthermia and its effects in middle cerebral artery occlusion in the rat","volume":"163","author":"Reglodi","year":"2000","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib47","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1161\/01.STR.30.4.736","article-title":"Stroke incidence and survival among middle-aged adults: 9-year follow-up of the Atherosclerosis Risk in Communities (ARIC) cohort","volume":"30","author":"Rosamond","year":"1999","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib48","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1161\/01.STR.13.3.290","article-title":"Survival and recurrence following stroke. The Framingham study","volume":"13","author":"Sacco","year":"1982","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib49","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0002-9343(01)00797-5","article-title":"Prospective evaluation of patients with syncope: a population-based study","volume":"111","author":"Sarasin","year":"2001","journal-title":"Am J Med"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib50","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1161\/01.STR.30.2.293","article-title":"Infarct volume as a surrogate or auxiliary outcome measure in ischemic stroke clinical trials. The RANTTAS Investigators","volume":"30","author":"Saver","year":"1999","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib51","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1161\/01.STR.0000226901.34927.10","article-title":"Inflammation and atherosclerosis: novel insights into plaque formation and destabilization","volume":"37","author":"Stoll","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib52","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0014-2999(98)00773-0","article-title":"Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion","volume":"362","author":"Takamatsu","year":"1998","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib53","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/jcbfm.1981.6","article-title":"Focal cerebral ischaemia in the rat. 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion","volume":"1","author":"Tamura","year":"1981","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib54","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.brainres.2006.05.049","article-title":"Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury","volume":"1101","author":"Tehranian","year":"2006","journal-title":"Brain Res"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib55","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1161\/01.STR.31.12.2912","article-title":"Effect of intravenous recombinant tissue plasminogen activator on ischemic stroke lesion size measured by computed tomography","volume":"31","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib56","first-page":"e85","article-title":"Heart disease and stroke statistics\u20142006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee","volume":"113","author":"Thom","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib57","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00401-004-0827-1","article-title":"The beneficial effect of mild hypothermia in a rat model of repeated thromboembolic insults","volume":"107","author":"Urrea","year":"2004","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib58","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00000658-198702000-00012","article-title":"Hypothermia-induced reversible platelet dysfunction","volume":"205","author":"Valeri","year":"1987","journal-title":"Ann Surg"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib59","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1161\/01.STR.23.4.576","article-title":"T2- and diffusion-weighted magnetic resonance imaging of a focal ischemic lesion in rat brain","volume":"23","author":"van Bruggen","year":"1992","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib60","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3171\/jns.1987.66.5.0748","article-title":"Argon laser-induced arterial photothrombosis. Characterization and possible application to therapy of arteriovenous malformations","volume":"66","author":"Watson","year":"1987","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib61","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1161\/hs0202.102730","article-title":"Cerebral blood flow restoration and reperfusion injury after ultraviolet laser-facilitated middle cerebral artery recanalization in rat thrombotic stroke","volume":"33","author":"Watson","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib62","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1097\/01.TA.0000064328.97941.FC","article-title":"A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function","volume":"56","author":"Wolberg","year":"2004","journal-title":"J Trauma"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib63","doi-asserted-by":"crossref","first-page":"723","DOI":"10.2176\/nmc.37.723","article-title":"Thread occlusion but not electrocoagulation of the middle cerebral artery causes hypothalamic damage with subsequent hyperthermia","volume":"37","author":"Yamashita","year":"1997","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib64","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1161\/01.STR.32.1.232","article-title":"Prolonged mild hypothermia therapy protects the brain against permanent focal ischemia","volume":"32","author":"Yanamoto","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib65","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1097\/00004647-199710000-00010","article-title":"A mouse model of embolic focal cerebral ischemia","volume":"17","author":"Zhang","year":"1997","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2007.01.018_bib66","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.1161\/01.STR.0000190007.18897.e3","article-title":"A model of mini-embolic stroke offers measurements of the neurovascular unit response in the living mouse","volume":"36","author":"Zhang","year":"2005","journal-title":"Stroke"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027007000428?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027007000428?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:11:24Z","timestamp":1759018284000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027007000428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":66,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0165027007000428"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2007.01.018","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of a thromboembolic photochemical model of repeated stroke in mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2007.01.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}