{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T10:44:46Z","timestamp":1788345886736,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.jneumeth.2009.12.004","type":"journal-article","created":{"date-parts":[[2009,12,23]],"date-time":"2009-12-23T07:05:34Z","timestamp":1261551934000},"page":"215-221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Development of animal model for vasculatic neuropathy: Induction by ischemic-reperfusion in the rat femoral artery"],"prefix":"10.1016","volume":"186","author":[{"given":"Arunachalam","family":"Muthuraman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muthusamy","family":"Ramesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailja","family":"Sood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2009.12.004_bib1","first-page":"149","article-title":"Effects of peripheral nerve ischemia\u2013reperfusion model on serum cytokine levels","volume":"18","author":"Bagdatoglu","year":"2008","journal-title":"Turk Neurosurg"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib2","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0304-3959(88)90209-6","article-title":"A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man","volume":"33","author":"Bennett","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib3","first-page":"E1","article-title":"Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits","volume":"261","author":"Cameron","year":"1991","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib4","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0022-3565(25)03823-6","article-title":"A method for determining loss of pain sensation","volume":"72","author":"D\u2019Amour","year":"1941","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1152\/physrev.00018.2001","article-title":"Free radicals in the physiological control of cell function","volume":"82","author":"Dr\u00f6ge","year":"2002","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0304-3959(02)00039-8","article-title":"Pharmacological characterization of the spared nerve injury model of neuropathic pain","volume":"98","author":"Erichsen","year":"2002","journal-title":"Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib7","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.semarthrit.2006.04.006","article-title":"Systemic rheumatoid vasculitis: a review","volume":"36","author":"Genta","year":"2006","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ejphar.2008.05.050","article-title":"The effects of simvastatin on ischemia\u2013reperfusion injury of sciatic nerve in adult rats","volume":"590","author":"Gholami","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib9","doi-asserted-by":"crossref","first-page":"4256","DOI":"10.3923\/pjbs.2007.4256.4260","article-title":"The effects of simvastatin on functional recovery of rat reperfused sciatic nerve","volume":"10","author":"Gholami","year":"2007","journal-title":"Pak J Biol Sci"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib10","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","article-title":"Analysis nitrate, nitrite and [15N] nitrate in biological fluids","volume":"126","author":"Green","year":"1982","journal-title":"Anal Biochem"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib11","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1161\/01.CIR.0000138743.09012.93","article-title":"Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins","volume":"110","author":"Haendeler","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib12","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(88)90026-7","article-title":"A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia","volume":"32","author":"Hargreaves","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib13","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S0014-4886(03)00385-6","article-title":"Peripheral nerve ischemia: reperfusion injury and fiber regeneration","volume":"184","author":"Iida","year":"2003","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib14","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0090-6980(01)00165-4","article-title":"The therapeutic effect of lipo PGE1 on diabetic neuropathy changes in endothelin and various angiopathic factors","volume":"66","author":"Itoh","year":"2001","journal-title":"Prostaglandins"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib15","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.ejim.2007.02.024","article-title":"Acute painless paraparesis due to bilateral femoral artery occlusion","volume":"18","author":"Iyadurai","year":"2007","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib16","first-page":"41","article-title":"Influence of immunosupression on nerve regeneration using allografts: an experimental study on rats","volume":"16","author":"J\u00fanior","year":"2008","journal-title":"Acta Ortop Bras"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib17","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/(SICI)1097-4598(199602)19:2<203::AID-MUS12>3.0.CO;2-V","article-title":"Efficacy of limb cooling on the salvage of peripheral nerve from ischemic fiber degeneration","volume":"19","author":"Kihara","year":"1996","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib18","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.aanat.2009.02.007","article-title":"Experimental models of peripheral neuropathic pain based on traumatic nerve injuries\u2014an anatomical perspective","volume":"191","author":"Klusakova","year":"2009","journal-title":"Ann Anat"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib19","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-3959(02)00484-0","article-title":"Tissue hypoxia in complex regional pain syndrome","volume":"104","author":"Koban","year":"2003","journal-title":"Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib20","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1001\/archneur.62.10.1570","article-title":"Skin denervation in vasculitic neuropathy","volume":"62","author":"Lee","year":"2005","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib21","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.burns.2008.08.009","article-title":"Causative factors affecting peripheral neuropathy in burn patients","volume":"35","author":"Lee","year":"2009","journal-title":"Burns"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib22","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.ejpain.2006.10.005","article-title":"Behavioral and sensory changes after direct ischemia\u2013reperfusion injury in rats","volume":"11","author":"Ludwig","year":"2007","journal-title":"Eur J Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib23","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.pain.2007.08.017","article-title":"The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1 beta, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice","volume":"137","author":"Martucci","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib24","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.phrs.2003.07.008","article-title":"The effect of alprostadil on ischemia\u2013reperfusion injury of peripheral nerve in rats","volume":"49","author":"Milcan","year":"2004","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib25","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.ejphar.2008.03.042","article-title":"Ameliorative effects of amiloride and pralidoxime in chronic constriction injury and vincristine induced painful neuropathy in rats","volume":"587","author":"Muthuraman","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0304-3959(77)90135-X","article-title":"Noxious thermal input from the rat tail: modulation by descending inhibitory influences","volume":"4","author":"Necker","year":"1978","journal-title":"Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib27","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.neuroscience.2009.02.047","article-title":"Independent alterations in the central and peripheral somatosensory pathways in rat diabetic neuropathy","volume":"160","author":"Piriz","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib28","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/(SICI)1098-2752(1999)19:8<374::AID-MICR5>3.0.CO;2-A","article-title":"Ischemia\u2013reperfusion injury of the peripheral nerve: an experimental study","volume":"19","author":"Saray","year":"1999","journal-title":"Microsurgery"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib29","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.tins.2009.01.010","article-title":"No no, no pain? The role of nitric oxide and cGMP in spinal pain processing","volume":"32","author":"Schmidtko","year":"2009","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib30","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.pain.2008.06.011","article-title":"A new rat model for thrombus-induced ischemic pain (TIIP): development of bilateral mechanical allodynia","volume":"139","author":"Seo","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib31","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1254\/jjp.16.287","article-title":"A modification of Haffner's method for testing analgesics","volume":"16","author":"Takagi","year":"1966","journal-title":"Jpn J Pharmacol"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib32","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.2337\/diacare.24.8.1468","article-title":"Dermal neurovascular dysfunction in type 2 diabetes","volume":"24","author":"Vinik","year":"2001","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib33","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.tox.2006.07.006","article-title":"Malondialdehyde and catalase as the serum biomarkers of allyl chloride-induced toxic neuropathy","volume":"227","author":"Wang","year":"2006","journal-title":"Toxicology"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib34","first-page":"107","article-title":"Simple procedure for specific enzyme of lipid hydroperoxides in serum or plasma","volume":"108","author":"Yagi","year":"1998","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jneumeth.2009.12.004_bib35","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.2337\/diab.42.10.1401","article-title":"Reduced motor nerve conduction velocity and Na(+)\u2013K(+)-ATPase activity in rats maintained on l-fucose diet","volume":"42","author":"Yorek","year":"1993","journal-title":"Diabetes"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027009006475?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027009006475?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:20:40Z","timestamp":1759018840000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027009006475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S0165027009006475"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2009.12.004","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of animal model for vasculatic neuropathy: Induction by ischemic-reperfusion in the rat femoral artery","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2009.12.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}