{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T23:41:05Z","timestamp":1768693265053,"version":"3.49.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1016\/j.jneumeth.2011.02.002","type":"journal-article","created":{"date-parts":[[2011,2,13]],"date-time":"2011-02-13T06:40:25Z","timestamp":1297579225000},"page":"92-96","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Characterization of a rat hypoxia-ischemia model where duration of hypoxia is determined by seizure activity"],"prefix":"10.1016","volume":"197","author":[{"given":"Jack R.","family":"Rivers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad A.","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Ashton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2011.02.002_bib0005","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1542\/peds.2004-0227","article-title":"The effect of chronic or intermittent hypoxia on cognition in childhood: a review of the evidence","volume":"114","author":"Bass","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0010","first-page":"83","article-title":"Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat","volume":"14","author":"Bayer","year":"1993","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0015","doi-asserted-by":"crossref","first-page":"E764","DOI":"10.1542\/peds.2007-3642","article-title":"Magnesium sulfate in severe perinatal asphyxia: a randomized, placebo-controlled trial","volume":"123","author":"Bhat","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0020","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/ar.1091560112","article-title":"The morphology of circuius arteriosus cerebri in rats","volume":"156","author":"Brown","year":"1966","journal-title":"Anat Rec"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0025","doi-asserted-by":"crossref","first-page":"179","DOI":"10.2165\/00023210-200317030-00004","article-title":"Therapeutic potential of cannabinoids in CNS disease","volume":"17","author":"Croxford","year":"2003","journal-title":"CNS Drugs"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0030","doi-asserted-by":"crossref","first-page":"S59","DOI":"10.1212\/WNL.51.3_Suppl_3.S59","article-title":"Clinical trials in acute stroke \u2013 why have they not been successful?","volume":"51","author":"del Zoppo","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0035","doi-asserted-by":"crossref","first-page":"E668","DOI":"10.1542\/peds.2008-2579","article-title":"Decreasing diagnoses of birth asphyxia in Canada: fact or artifact","volume":"123","author":"Dzakpasu","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0040","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0006-8993(90)90763-2","article-title":"Effects of hypoxia-ischemia and seizures on neuronal and glial-like C-FOS protein-levels in the infant rat","volume":"531","author":"Gunn","year":"1990","journal-title":"Brain Res"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0045","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.eplepsyres.2007.07.003","article-title":"Domoic acid preconditioning and seizure induction in young and aged rats","volume":"76","author":"Hesp","year":"2007","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0050","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.resuscitation.2008.04.027","article-title":"Therapeutic hypothermia in neonates. Review of current clinical data, ILCOR recommendations and suggestions for implementation in neonatal intensive care units","volume":"78","author":"Hoehn","year":"2008","journal-title":"Resuscitation"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0055","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0024-3205(91)90448-K","article-title":"Differential-effects of perinatal hypoxia and anoxia on long-term seizure susceptibility in the rat","volume":"49","author":"Jensen","year":"1991","journal-title":"Life Sci"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0060","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.brainresprot.2003.12.001","article-title":"An optimized triphenyltetrazolium chloride method for identification of cerebral infarcts","volume":"13","author":"Joshi","year":"2004","journal-title":"Brain Res Protoc"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0065","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1161\/01.STR.24.1.117","article-title":"Effect of brain edema on infarct volume in a focal cerebral-ischemia model in rats","volume":"24","author":"Lin","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0070","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/ilar.47.1.32","article-title":"Brief update on animal models of hypoxic-ischemic encephalopathy and neonatal stroke","volume":"47","author":"Northington","year":"2006","journal-title":"ILAR J"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0075","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1111\/j.1528-1157.1999.tb00885.x","article-title":"Antidepressant drugs and seizure susceptibility: from in vitro data to clinical practice","volume":"40","author":"Pisani","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0080","first-page":"511","article-title":"Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models","volume":"108","author":"Rice","year":"2000","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0085","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic-ischemic brain-damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0090","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2174\/187152410790780145","article-title":"The development of cannabinoid CBII receptor agonists for the treatment of central neuropathies","volume":"10","author":"Rivers","year":"2010","journal-title":"Cent Nerv Syst Agents Med Chem"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0095","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0887-8994(93)90061-G","article-title":"Brain injury and protective effects of hypothermia using triphenyltetrazolium chloride in neonatal rat","volume":"9","author":"Saeed","year":"1993","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0100","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0006-8993(98)00892-0","article-title":"Strain-related brain injury in neonatal mice subjected to hypoxia-ischemia","volume":"810","author":"Sheldon","year":"1998","journal-title":"Brain Res"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0105","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1002\/(SICI)1097-4547(19990115)55:2<158::AID-JNR3>3.0.CO;2-1","article-title":"Rat model of perinatal hypoxic-ischemic brain damage","volume":"55","author":"Vannucci","year":"1999","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0110","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/(SICI)1098-2779(1997)3:1<69::AID-MRDD9>3.0.CO;2-S","article-title":"Glucose, acidosis, and perinatal hypoxic-ischemic brain damage","volume":"3","author":"Vannucci","year":"1997","journal-title":"Ment Retard Dev Disabil Res Rev"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0115","series-title":"Manual of stroke models in rats","year":"2009"},{"key":"10.1016\/j.jneumeth.2011.02.002_bib0120","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1203\/00006450-200110000-00005","article-title":"Prolonged seizures exacerbate perinatal hypoxic-ischemic brain damage","volume":"50","author":"Wirrell","year":"2001","journal-title":"Pediatr Res"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016502701100077X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016502701100077X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:25:13Z","timestamp":1759019113000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016502701100077X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S016502701100077X"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2011.02.002","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of a rat hypoxia-ischemia model where duration of hypoxia is determined by seizure activity","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2011.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown copyright \u00a9 2011 Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}