{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T03:13:36Z","timestamp":1773371616573,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Research Grants Council of the Hong Kong Special Administrative Region, China","award":["PolyU5633\/07M"],"award-info":[{"award-number":["PolyU5633\/07M"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.jneumeth.2012.07.024","type":"journal-article","created":{"date-parts":[[2012,8,9]],"date-time":"2012-08-09T16:16:14Z","timestamp":1344528974000},"page":"272-280","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of transcranial Doppler flow velocity changes in intracerebral hemorrhage rats using ultrasonography"],"prefix":"10.1016","volume":"210","author":[{"given":"Zheng","family":"Ke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Ying","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-yu","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2012.07.024_bib0005","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1161\/01.STR.17.3.472","article-title":"Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination","volume":"17","author":"Bederson","year":"1986","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0010","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/nbm.705","article-title":"MR angiographic investigation of transient focal cerebral ischemia in rat","volume":"14","author":"Besselmann","year":"2001","journal-title":"NMR Biomed"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0015","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1161\/01.STR.17.5.913","article-title":"Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study","volume":"17","author":"Bishop","year":"1986","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0020","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.ultrasmedbio.2007.11.018","article-title":"Ultrasonic assessment of cerebral blood flow changes during ischemia-reperfusion in 7-day-old rats","volume":"34","author":"Bonnin","year":"2008","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0025","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/01.WCB.0000057741.00152.E4","article-title":"Arteriogenesis in hypoperfused rat brain","volume":"23","author":"Busch","year":"2003","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0030","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1161\/01.STR.20.10.1383","article-title":"Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats","volume":"20","author":"De Ryck","year":"1989","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0035","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0301-5629(99)00049-6","article-title":"Comparison of transcranial Doppler flow velocity and cerebral blood flow during focal ischemia in rabbits","volume":"25","author":"Els","year":"1999","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0040","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1161\/01.STR.4.5.795","article-title":"The effects of increased intracranial pressure on flow through major cerebral arteries in vitro","volume":"4","author":"Farrar","year":"1973","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0045","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1148\/radiology.207.2.9577469","article-title":"Research directions in MR imaging","volume":"207","author":"Glover","year":"1998","journal-title":"Radiology"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0050","first-page":"457","article-title":"Effect of delayed argatroban treatment on intracerebral hemorrhage-induced edema in the rat","volume":"86","author":"Kitaoka","year":"2003","journal-title":"Acta Neurochir Suppl"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0055","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.ultrasmedbio.2010.01.005","article-title":"Evaluation of cerebral blood flow changes in focal cerebral ischemia rats by using transcranial Doppler ultrasonography","volume":"36","author":"Li","year":"2010","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0060","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1161\/STROKEAHA.110.594457","article-title":"Rodent models of intracerebral hemorrhage","volume":"41","author":"MacLellan","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0065","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/sj.jcbfm.9600548","article-title":"Intracerebral hemorrhage models in rat: comparing collagenase to blood infusion","volume":"28","author":"MacLellan","year":"2008","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0070","first-page":"1441","article-title":"Dynamic CT perfusion imaging of acute stroke","volume":"21","author":"Mayer","year":"2000","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0075","series-title":"Measurement in physical education","author":"Meyers","year":"1962"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0080","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3171\/jns.1987.66.4.0555","article-title":"Effects of experimental intracerebral hemorrhage on blood flow, capillary permeability, and histochemistry","volume":"66","author":"Nath","year":"1987","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0085","doi-asserted-by":"crossref","first-page":"415","DOI":"10.3171\/jns.1992.76.3.0415","article-title":"The relationship of blood flow velocity fluctuations to intracranial pressure B waves","volume":"76","author":"Newell","year":"1992","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0090","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1161\/01.STR.0000132195.17366.2b","article-title":"Cerebral venous flow velocity predicts poor outcome in subarachnoid hemorrhage","volume":"35","author":"Niesen","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0095","doi-asserted-by":"crossref","first-page":"13007","DOI":"10.1523\/JNEUROSCI.4323-06.2006","article-title":"A neurovascular niche for neurogenesis after stroke","volume":"26","author":"Ohab","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0100","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1002\/ana.410110306","article-title":"Cerebral blood flow after experimental basal ganglia hemorrhage","volume":"11","author":"Ropper","year":"1982","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0105","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1161\/01.STR.21.5.801","article-title":"Collagenase induced intracerebral hemorrhage in rats","volume":"21","author":"Rosenberg","year":"1990","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0115","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1161\/01.STR.0000080942.32331.39","article-title":"Assessment of cerebral blood flow by means of blood-flow-volume measurement in the internal carotid artery: comparative study with a 133xenon clearance technique","volume":"34","author":"Soustiel","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0125","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0006-8993(95)00657-C","article-title":"Local hemodynamic changes during transient middle cerebral artery occlusion and recirculation in the rat","volume":"691","author":"Takagi","year":"1995","journal-title":"Brain Res"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0155","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1161\/01.STR.0000259712.64772.85","article-title":"Validation of transcranial Doppler with computed tomography angiography in acute cerebral ischemia","volume":"38","author":"Tsivgoulis","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0130","series-title":"Manual of stroke models in rats","author":"Wang-Fischer","year":"2009"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0135","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1097\/01.WCB.0000095799.98378.7D","article-title":"Quantitative cerebral blood flow measurements in the rat using a beta-probe and H215O","volume":"23","author":"Weber","year":"2003","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0140","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1161\/hs1201.099820","article-title":"Mechanisms of edema formation after intracerebral hemorrhage: effects of extravasated red blood cells on blood flow and blood\u2013brain barrier integrity","volume":"32","author":"Xi","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0145","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S1474-4422(05)70283-0","article-title":"Mechanisms of brain injury after intracerebral hemorrhage","volume":"5","author":"Xi","year":"2006","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jneumeth.2012.07.024_bib0150","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3171\/jns.1994.81.1.0093","article-title":"Experimental intracerebral hemorrhage: relationship between brain edema, blood flow, and blood\u2013brain barrier permeability in rats","volume":"81","author":"Yang","year":"1994","journal-title":"J Neurosurg"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027012002889?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027012002889?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:29:56Z","timestamp":1759019396000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027012002889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S0165027012002889"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2012.07.024","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of transcranial Doppler flow velocity changes in intracerebral hemorrhage rats using ultrasonography","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2012.07.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}