{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:12:19Z","timestamp":1762431139763,"version":"3.44.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,4,29]],"date-time":"2016-04-29T00:00:00Z","timestamp":1461888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes for Health Research","doi-asserted-by":"crossref","award":["MOP111037"],"award-info":[{"award-number":["MOP111037"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100009408","name":"Brain Canada","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009408","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.jneumeth.2016.04.025","type":"journal-article","created":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T23:29:54Z","timestamp":1462058994000},"page":"56-65","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Model of minor stroke with mild peri-infarct ischemic injury"],"prefix":"10.1016","volume":"268","author":[{"given":"Ursula I.","family":"Tuor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinbo","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dave","family":"Rushforth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taduesz","family":"Foniok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2016.04.025_bib0005","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.neuroscience.2008.09.015","article-title":"Acute but not chronic differences in skilled reaching for food following motor cortex devascularization vs. photothrombotic stroke in the rat","volume":"157","author":"Alaverdashvili","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0010","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jneumeth.2015.03.029","article-title":"Laser system refinements to reduce variability in infarct size in the rat photothrombotic stroke model","volume":"247","author":"Alaverdashvili","year":"2015","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/1056-8719(92)90013-Q","article-title":"Photochemically induced, graded cerebral infarction in the mouse by laser irradiation evolution of brain edema","volume":"27","author":"Boquillon","year":"1992","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0020","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/ana.24026","article-title":"Diffusion-weighted imaging and diagnosis of transient ischemic attack","volume":"75","author":"Brazzelli","year":"2014","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0025","doi-asserted-by":"crossref","first-page":"e47792","DOI":"10.1371\/journal.pone.0047792","article-title":"Protection against recurrent stroke with resveratrol: endothelial protection","volume":"7","author":"Clark","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0030","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/jcbfm.1986.31","article-title":"Photochemically induced cortical infarction in the rat. 1. Time course of hemodynamic consequences","volume":"6","author":"Dietrich","year":"1986","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0035","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1007\/BF00687263","article-title":"Photochemically induced cerebral infarction. II. Edema and blood-brain barrier disruption","volume":"72","author":"Dietrich","year":"1987","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0040","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/BF00687262","article-title":"Photochemically induced cerebral infarction. I. Early microvascular alterations","volume":"72","author":"Dietrich","year":"1987","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0045","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1161\/STROKEAHA.108.192218","volume":"40","author":"Easton","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0050","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1161\/STROKEAHA.114.007581","article-title":"Cortical selective neuronal loss, impaired behavior, and normal magnetic resonance imaging in a new rat model of true transient ischemic attacks","volume":"46","author":"Ejaz","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0055","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0165-0270(99)00041-2","article-title":"Long-term cortical CBF recording by laser-Doppler flowmetry in awake freely moving rats subjected to reversible photothrombotic stroke","volume":"90","author":"Gu","year":"1999","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0060","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1161\/STROKEAHA.113.001272","article-title":"Displacement of sensory maps and disorganization of motor cortex after targeted stroke in mice","volume":"44","author":"Harrison","year":"2013","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0065","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1161\/01.STR.32.5.1208","article-title":"Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain","volume":"32","author":"Ito","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0070","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.neulet.2007.09.043","article-title":"Subacute hemorrhage and resolution of edema in Rose Bengal stroke model in rats coincides with improved sensorimotor functions","volume":"428","author":"Jolkkonen","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0075","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.nbd.2014.07.005","article-title":"Dynamic perfusion and diffusion MRI of cortical spreading depolarization in photothrombotic ischemia","volume":"71C","author":"Kao","year":"2014","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0080","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1161\/STR.0000000000000024","article-title":"Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"45","author":"Kernan","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0085","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1161\/01.STR.27.11.2110","article-title":"Evolution of photochemically induced focal cerebral ischemia in the rat: magnetic resonance imaging and histology","volume":"27","author":"Lee","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0090","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1179\/1743132814Y.0000000406","article-title":"Alterations in the gray matter volume in transient ischemic attack: a voxel-based morphometry study","volume":"37","author":"Li","year":"2015","journal-title":"Neurol. Res."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0095","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.expneurol.2009.04.021","article-title":"Both compensation and recovery of skilled reaching following small photothrombotic stroke to motor cortex in the rat","volume":"218","author":"Moon","year":"2009","journal-title":"Exp. Neurol."},{"year":"1998","series-title":"The Rat Brain in Sterotaxic Coordinates","author":"Paxinos","key":"10.1016\/j.jneumeth.2016.04.025_bib0100"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0105","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S1056-8719(01)00153-8","article-title":"A photothrombotic model of small early ischemic infarcts in the rat brain with histologic and MRI correlation","volume":"45","author":"Pevsner","year":"2001","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0110","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1148\/radiology.189.2.8210373","article-title":"Histopathologic correlates of abnormal water diffusion in cerebral ischemia: diffusion-weighted MR imaging and light and electron microscopic study","volume":"189","author":"Pierpaoli","year":"1993","journal-title":"Radiology"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0115","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s10334-004-0058-4","article-title":"Cerebral blood flow response during hypoxia-ischemia and reperfusion differs in neonatal and juvenile rats","volume":"17","author":"Qiao","year":"2004","journal-title":"MAGMA"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0120","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.jneumeth.2009.08.010","article-title":"Development of a model of recurrent stroke consisting of a mild transient stroke followed by a second moderate stroke in rats","volume":"184","author":"Qiao","year":"2009","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0125","doi-asserted-by":"crossref","first-page":"5128","DOI":"10.1523\/JNEUROSCI.2810-14.2015","article-title":"Delayed inhibition of VEGF signaling after stroke attenuates blood-brain barrier breakdown and improves functional recovery in a comorbidity-dependent manner","volume":"35","author":"Reeson","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0130","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0006-8993(00)02513-0","article-title":"Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration","volume":"874","author":"Schmued","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0135","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1038\/jcbfm.2014.147","article-title":"Monitoring stroke progression: in vivo imaging of cortical perfusion, blood-brain barrier permeability and cellular damage in the rat photothrombosis model","volume":"34","author":"Schoknecht","year":"2014","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0140","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s004010000262","article-title":"Dynamic changes of magnetic resonance imaging abnormalities in relation to inflammation and glial responses after photothrombotic cerebral infarction in the rat brain","volume":"101","author":"Schroeter","year":"2001","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0145","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nn.3278","article-title":"The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit","volume":"16","author":"Shih","year":"2013","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0150","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1161\/01.STR.23.4.576","article-title":"T2- and diffusion-weighted magnetic resonance imaging of a focal ischemic lesion in rat brain","volume":"23","author":"Van Bruggen","year":"1992","journal-title":"Stroke"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0155","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/BF01405538","article-title":"Photochemically-induced cerebral infarction in the rat: comparison of NMR imaging and histologic changes","volume":"122","author":"Verlooy","year":"1993","journal-title":"Acta Neurochir. (Wien)"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0160","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/ana.410170513","article-title":"Induction of reproducible brain infarction by photochemically initiated thrombosis","volume":"17","author":"Watson","year":"1985","journal-title":"Ann. Neurol."},{"issue":"Pt 6","key":"10.1016\/j.jneumeth.2016.04.025_bib0165","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1093\/brain\/116.6.1509","article-title":"The case of aphasia or neglect after striatocapsular infarction","volume":"116","author":"Weiller","year":"1993","journal-title":"Brain"},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0170","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1073\/pnas.89.1.212","article-title":"Magnetic resonance imaging of perfusion using spin inversion of arterial water","volume":"89","author":"Williams","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0175","doi-asserted-by":"crossref","first-page":"5333","DOI":"10.1523\/JNEUROSCI.1085-05.2005","article-title":"Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia","volume":"25","author":"Zhang","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2016.04.025_bib0180","doi-asserted-by":"crossref","first-page":"e119","DOI":"10.1371\/journal.pbio.0050119","article-title":"Imaging the impact of cortical microcirculation on synaptic structure and sensory-evoked hemodynamic responses in vivo","volume":"5","author":"Zhang","year":"2007","journal-title":"PLoS Biol."}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027016300772?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027016300772?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:39:35Z","timestamp":1759019975000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027016300772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":36,"alternative-id":["S0165027016300772"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2016.04.025","relation":{},"ISSN":["0165-0270"],"issn-type":[{"type":"print","value":"0165-0270"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Model of minor stroke with mild peri-infarct ischemic injury","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2016.04.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}