{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T22:20:07Z","timestamp":1789942807655,"version":"4.0.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP17dm0207052"],"award-info":[{"award-number":["JP17dm0207052"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17H05565"],"award-info":[{"award-number":["17H05565"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["26112002"],"award-info":[{"award-number":["26112002"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.jneumeth.2018.10.023","type":"journal-article","created":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T02:46:02Z","timestamp":1540003562000},"page":"147-155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Enhancement of the transduction efficiency of a lentiviral vector for neuron-specific retrograde gene delivery through the point mutation of fusion glycoprotein type E"],"prefix":"10.1016","volume":"311","author":[{"given":"Shigeki","family":"Kato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masateru","family":"Sugawara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichi","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Takada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuto","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2018.10.023_bib0005","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nature02544","article-title":"VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model","volume":"429","author":"Azzouz","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0010","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/jnr.20696","article-title":"1-Methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu\/Zn superoxide dismutase","volume":"83","author":"Barkats","year":"2006","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0015","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1006\/exnr.1998.6878","article-title":"Neuroprotection of spinal motoneurons following targeted transduction with an adenoviral vector carrying the gene for glial cell line-derived neurotrophic factor","volume":"153","author":"Baumgartner","year":"1998","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0020","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1038\/sj.mt.6300159","article-title":"Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells","volume":"15","author":"Beard","year":"2007","journal-title":"Mol. Ther."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0025","doi-asserted-by":"crossref","first-page":"8979","DOI":"10.1523\/JNEUROSCI.0409-15.2015","article-title":"Monosynaptic circuit tracing with glycoprotein-deleted rabies viruses","volume":"35","author":"Callaway","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0030","doi-asserted-by":"crossref","first-page":"387","DOI":"10.2174\/1566523054546224","article-title":"Altering the tropism of lentiviral vectors through pseudotyping","volume":"5","author":"Cronin","year":"2005","journal-title":"Curr. Gene Ther."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0035","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1128\/jvi.46.1.162-169.1983","article-title":"Nucleotide sequence of a cDNA clone encoding the entire glycoprotein rom the New Jersey serotype of vesicular stomatitis virus","volume":"46","author":"Gallione","year":"1983","journal-title":"J. Virol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0040","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1099\/0022-1317-77-10-2437","article-title":"Rabies virus binding to the nicotinic acetylcholine receptor \u03b1 subunit demonstrated by virus overlay protein binding assay","volume":"77","author":"Gastka","year":"1996","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0045","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/nm0797-765","article-title":"Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons","volume":"3","author":"Gravel","year":"1997","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0050","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1126\/science.1088547","article-title":"LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1","volume":"302","author":"Hacein-Bey-Abina","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0055","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.1182\/blood-2004-01-0045","article-title":"Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system","volume":"103","author":"Hanawa","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0060","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1006\/mthe.2002.0549","article-title":"Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood","volume":"5","author":"Hanawa","year":"2002","journal-title":"Mol. Ther."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0065","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1128\/jvi.67.1.530-542.1993","article-title":"Evidence from the anti-idiotypic network that the acetylcholine receptor is a rabies virus receptor","volume":"67","author":"Hanham","year":"1993","journal-title":"J. Virol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0039149","article-title":"Immunotoxin-mediated tract targeting in the primate brain: selective elimination of the cortico-subthalamic \u201chyperdirect\u201d pathway","volume":"7","author":"Inoue","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0075","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1523\/JNEUROSCI.2399-15.2016","article-title":"Causal link between the cortico-rubral pathway and functional recovery through forced impaired limb use in rats with stroke","volume":"36","author":"Ishida","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0080","doi-asserted-by":"crossref","first-page":"17169","DOI":"10.1523\/JNEUROSCI.4005-11.2011","article-title":"Selective neural pathway targeting reveals key roles of thalamostriatal projection in the control of visual discrimination","volume":"31","author":"Kato","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0085","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1089\/hum.2009.179","article-title":"A lentiviral strategy for highly efficient retrograde gene transfer by pseudotyping with fusion envelope glycoprotein","volume":"22","author":"Kato","year":"2011","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0090","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1089\/hum.2011.111","article-title":"Neuron-specific gene transfer through retrograde transport of lentiviral vector pseudotyped with a novel type of fusion envelope glycoprotein","volume":"22","author":"Kato","year":"2011","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0095","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jneumeth.2014.02.015","article-title":"Improved transduction efficiency of a lentiviral vector for neuron-specific retrograde gene transfer by optimizing the junction of fusion envelope glycoprotein","volume":"227","author":"Kato","year":"2014","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0100","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1016\/j.celrep.2018.02.016","article-title":"Action selection and flexible switching controlled by intralaminar thalamic neurons","volume":"22","author":"Kato","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0105","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nature11206","article-title":"Genetic dissection of the circuit for hand dexterity in primates","volume":"487","author":"Kinoshita","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0110","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/978-1-4939-3271-9_12","article-title":"Altering entry site preference of lentiviral vectors into neuronal cells by pseudotyping with envelope glycoproteins","volume":"1382","author":"Kobayashi","year":"2016","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0115","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3389\/fnana.2017.00065","article-title":"Pseudotyped lentiviral vectors for retrograde gene delivery into target brain regions","volume":"11","author":"Kobayashi","year":"2017","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0120","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00702-016-1674-7","article-title":"Genetic manipulation of specific neural circuits by use of a viral vector system","volume":"125","author":"Kobayashi","year":"2018","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0125","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1126\/science.1068893","article-title":"Murine leukemia induced by retroviral gene marking","volume":"296","author":"Li","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0130","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nm.1863","article-title":"Development of a novel mouse glioma model using lentiviral vectors","volume":"15","author":"Marumoto","year":"2009","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0135","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/nn.4463","article-title":"Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ","volume":"20","author":"Matsuda","year":"2017","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0140","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0378-1119(91)90434-D","article-title":"Efficient selection for high-expression transfectants with a novel eukaryotic vector","volume":"108","author":"Niwa","year":"1991","journal-title":"Gene"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0145","series-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2001"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0150","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1046\/j.1460-9568.2000.00098.x","article-title":"IAP family proteins delay motoneuron cell death in vivo","volume":"2","author":"Perrelet","year":"2000","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0155","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/jnr.10558","article-title":"Adenoviral gene transfer of GDNF, BDNF and TGF2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion","volume":"72","author":"Sakamoto","year":"2003","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0160","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/BF01310002","article-title":"Role of phospholipids in rhabdovirus attachment to CER cells. Brief report","volume":"81","author":"Superti","year":"1984","journal-title":"Arch. Virol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0165","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037551","article-title":"Development of cysteine-free fluorescent proteins for the oxidative environment","volume":"7","author":"Suzuki","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0170","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.neures.2017.02.007","article-title":"The use of an optimized chimeric envelope glycoprotein enhances the efficiency of retrograde gene transfer of a pseudotyped lentiviral vector in the primate brain","volume":"120","author":"Tanabe","year":"2017","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0175","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.neuron.2016.09.021","article-title":"A designer AAV variant permits efficient retrograde access to projection neurons","volume":"92","author":"Tervo","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0180","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.ymthe.2005.07.358","article-title":"Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice","volume":"12","author":"Themis","year":"2005","journal-title":"Mol. Ther."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0185","doi-asserted-by":"crossref","first-page":"7181","DOI":"10.1128\/JVI.72.9.7181-7190.1998","article-title":"The neural cell adhesion molecule is a receptor for rabies virus","volume":"72","author":"Thoulouze","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0190","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/mt.2010.260","article-title":"Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefits in fALS mice","volume":"19","author":"Towne","year":"2011","journal-title":"Mol. Ther."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0195","doi-asserted-by":"crossref","first-page":"7250","DOI":"10.1093\/emboj\/17.24.7250","article-title":"Low-affinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus","volume":"17","author":"Tuffereau","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0200","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1099\/vir.0.2008\/000349-0","article-title":"Investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison","volume":"89","author":"Wright","year":"2008","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.jneumeth.2018.10.023_bib0205","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.molbrainres.2004.06.029","article-title":"Delayed gene therapy of glial cell Line-derived neurotrophic factor is efficacious in a rat model of Parkinson\u2019s disease","volume":"134","author":"Zheng","year":"2005","journal-title":"Mol Brain Res"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027018303376?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027018303376?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:48:19Z","timestamp":1759020499000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027018303376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":41,"alternative-id":["S0165027018303376"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2018.10.023","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhancement of the transduction efficiency of a lentiviral vector for neuron-specific retrograde gene delivery through the point mutation of fusion glycoprotein type E","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2018.10.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}