{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T11:24:47Z","timestamp":1778671487519,"version":"3.51.4"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100010664","name":"H2020 Future and Emerging Technologies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010664","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011273","name":"FP7 Information and Communication Technologies","doi-asserted-by":"publisher","award":["ICT-215910"],"award-info":[{"award-number":["ICT-215910"]}],"id":[{"id":"10.13039\/100011273","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["STA 431\/14-2"],"award-info":[{"award-number":["STA 431\/14-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SOD1G93A"],"award-info":[{"award-number":["SOD1G93A"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.jneumeth.2019.108532","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T19:39:29Z","timestamp":1574883569000},"page":"108532","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Recommendations for measuring whisker movements and locomotion in mice with sensory, motor and cognitive deficits"],"prefix":"10.1016","volume":"331","author":[{"given":"Ugne","family":"Simanaviciute","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jewel","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard E","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Connor-Robson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy D.","family":"Farr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emre","family":"Fertan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikki","family":"Gambles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huw","family":"Garland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Jennifer","family":"Morton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen F.","family":"Staiger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Skillings","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca C.","family":"Trueman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Wade-Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigel I.","family":"Wood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aimee A.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3968-8370","authenticated-orcid":false,"given":"Robyn A.","family":"Grant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"13","key":"10.1016\/j.jneumeth.2019.108532_bib0005","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/j.cub.2014.05.036","article-title":"Strategy change in vibrissal active sensing during rat locomotion","volume":"24","author":"Arkley","year":"2014","journal-title":"Curr. Biol."},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0010","doi-asserted-by":"crossref","first-page":"e89454","DOI":"10.1371\/journal.pone.0089454","article-title":"Galantamine slows down plaque formation and behavioral decline in the 5XFAD mouse model of Alzheimer\u2019s disease","volume":"9","author":"Bhattacharya","year":"2014","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.jneumeth.2019.108532_bib0015","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00401-010-0734-6","article-title":"Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting A\u03b2 and tau pathologies in 3xTg-AD mice","volume":"120","author":"Blanchard","year":"2010","journal-title":"Acta Neuropathol."},{"issue":"4","key":"10.1016\/j.jneumeth.2019.108532_bib0020","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.conb.2007.07.008","article-title":"Barrel cortex and whisker-mediated behaviors","volume":"17","author":"Brecht","year":"2007","journal-title":"Curr. Opin. Neurobiol."},{"issue":"7","key":"10.1016\/j.jneumeth.2019.108532_bib0025","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1111\/j.1460-9568.2007.05831.x","article-title":"Vacuolization correlates with spin\u2013spin relaxation time in motor brainstem nuclei and behavioural tests in the transgenic G93A\u2010SOD1 mouse model of ALS","volume":"26","author":"Bucher","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0030","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ejphar.2015.03.021","article-title":"Mouse models rarely mimic the transcriptome of human neurodegenerative diseases: a systematic bioinformatics-based critique of preclinical models","volume":"759","author":"Burns","year":"2015","journal-title":"Eur. J. Pharmacol."},{"issue":"8","key":"10.1016\/j.jneumeth.2019.108532_bib0035","doi-asserted-by":"crossref","first-page":"3248","DOI":"10.1523\/JNEUROSCI.19-08-03248.1999","article-title":"Characterization of progressive motor deficits in mice transgenic for the human Huntington\u2019s disease mutation","volume":"19","author":"Carter","year":"1999","journal-title":"J. Neurosci."},{"issue":"8","key":"10.1016\/j.jneumeth.2019.108532_bib0040","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1523\/JNEUROSCI.10-08-02638.1990","article-title":"Biometric analyses of vibrissal tactile discrimination in the rat","volume":"10","author":"Carvell","year":"1990","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.jneumeth.2019.108532_bib0045","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0042-6989(01)00146-8","article-title":"Retinal degeneration mutants in the mouse","volume":"42","author":"Chang","year":"2002","journal-title":"Vision Res."},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0050","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s12035-012-8375-5","article-title":"A non-transgenic mouse model (icv-STZ mouse) of Alzheimer\u2019s disease: similarities to and differences from the transgenic model (3xTg-AD mouse)","volume":"47","author":"Chen","year":"2013","journal-title":"Mol. Neurobiol."},{"issue":"5","key":"10.1016\/j.jneumeth.2019.108532_bib0055","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.exer.2005.06.004","article-title":"Mouse mutants as models for congenital retinal disorders","volume":"81","author":"Dalke","year":"2005","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0060","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/nrn2411","article-title":"\u2019Where\u2019 and\u2019 what\u2019 in the whisker sensorimotor system","volume":"9","author":"Diamond","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0065","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/BF02996215","article-title":"Two new mutants,\u2018trembler\u2019and \u2018reeler\u2019, with neurological actions in the house mouse (Mus musculus L.)","volume":"50","author":"Falconer","year":"1951","journal-title":"J. Genet."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0070","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.pneurobio.2012.11.002","article-title":"Barrel cortex function","volume":"103","author":"Feldmeyer","year":"2013","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0075","doi-asserted-by":"crossref","first-page":"111937","DOI":"10.1016\/j.bbr.2019.111937","article-title":"Age and sex differences in motivation and spatial working memory in 3xTg-AD mice in the Hebb\u2013Williams maze","volume":"370","author":"Fertan","year":"2019","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.jneumeth.2019.108532_bib0080","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/gbb.12133","article-title":"Abnormal vibrissa\u2010related behavior and loss of barrel field inhibitory neurons in 5xFAD transgenics","volume":"13","author":"Flanigan","year":"2014","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0085","volume":"vol. 3","author":"Fox","year":"2006"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0090","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jneumeth.2017.04.020","article-title":"Characterisation of progressive motor deficits in whisker movements in R6\/2, Q175 and Hdh knock-in mouse models of Huntington\u2019s disease","volume":"300","author":"Garland","year":"2018","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0095","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.bbr.2018.09.006","article-title":"Motor deficits in 16-month-old male and female 3xTg-AD mice","volume":"356","author":"Garvock-de Montbrun","year":"2019","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0100","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.conb.2018.04.028","article-title":"Constraints on somatosensory map development: mutants lead the way","volume":"53","author":"Gaspar","year":"2018","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneumeth.2019.108440","article-title":"Description and validation of the LocoWhisk system: quantifying rodent exploratory, sensory and motor behaviours","author":"Gillespie","year":"2019","journal-title":"Journal of Neuroscience Methods. This Issue."},{"issue":"1880","key":"10.1016\/j.jneumeth.2019.108532_bib0110","article-title":"Whisker touch sensing guides locomotion in small, quadrupedal mammals","volume":"285","author":"Grant","year":"2018","journal-title":"Proceedings of the Royal Society B: Biological Sciences"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0115","article-title":"Whisker exploration behaviours in the 5xFAD mouse are affected by sex and retinal degeneration","author":"Grant","year":"2018","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0120","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.beproc.2016.03.021","article-title":"The effects of smoking on whisker movements: a quantitative measure of exploratory behaviour in rodents","volume":"128","author":"Grant","year":"2016","journal-title":"Behav. Processes"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0125","doi-asserted-by":"crossref","DOI":"10.1152\/jn.90783.2008","article-title":"Active touch sensing in the rat: anticipatory and regulatory control of whisker movements during surface exploration","author":"Grant","year":"2009","journal-title":"J. Neurophysiol."},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0130","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/dev.20591","article-title":"The development of whisker control in rats in relation to locomotion","volume":"54","author":"Grant","year":"2012","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0135","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.bbr.2013.11.002","article-title":"Abnormalities in whisking behaviour are associated with lesions in brain stem nuclei in a mouse model of amyotrophic lateral sclerosis","volume":"259","author":"Grant","year":"2014","journal-title":"Behav. Brain Res."},{"issue":"7","key":"10.1016\/j.jneumeth.2019.108532_bib0140","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1002\/jnr.24418","article-title":"Interval timing is disrupted in female 5xFAD mice: an indication of altered memory processes","volume":"97","author":"G\u00fcr","year":"2019","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0145","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3389\/fnana.2017.00054","article-title":"The functioning of a cortex without layers","volume":"11","author":"Guy","year":"2017","journal-title":"Front. Neuroanat."},{"issue":"9","key":"10.1016\/j.jneumeth.2019.108532_bib0150","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1093\/cercor\/bhu052","article-title":"Persistence of functional sensory maps in the absence of cortical layers in the somatosensory cortex of reeler mice","volume":"25","author":"Guy","year":"2014","journal-title":"Cereb. Cortex"},{"issue":"1","key":"10.1016\/j.jneumeth.2019.108532_bib0155","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1750-1326-9-13","article-title":"Abundance of A\u03b2 5-x like immunoreactivity in transgenic 5XFAD, APP\/PS1KI and 3xTG mice, sporadic and familial Alzheimer\u2019s disease","volume":"9","author":"Guzm\u00e1n","year":"2014","journal-title":"Mol. Neurodegener."},{"issue":"1-2","key":"10.1016\/j.jneumeth.2019.108532_bib0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jns.2005.02.006","article-title":"Background and gender effects on survival in the TgN (SOD1-G93A) 1Gur mouse model of ALS","volume":"236","author":"Heiman-Patterson","year":"2005","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0165","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jneumeth.2017.04.006","article-title":"A novel automated rodent tracker (ART), demonstrated in a mouse model of amyotrophic lateral sclerosis","volume":"300","author":"Hewitt","year":"2018","journal-title":"J. Neurosci. Methods"},{"issue":"7724","key":"10.1016\/j.jneumeth.2019.108532_bib0170","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1038\/s41586-018-0527-y","article-title":"Sensation, movement and learning in the absence of barrel cortex","volume":"561","author":"Hong","year":"2018","journal-title":"Nature"},{"issue":"18","key":"10.1016\/j.jneumeth.2019.108532_bib0175","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1242\/jeb.105338","article-title":"The search space of the rat during whisking behavior","volume":"217","author":"Huet","year":"2014","journal-title":"J. Exp. Biol."},{"issue":"42","key":"10.1016\/j.jneumeth.2019.108532_bib0180","doi-asserted-by":"crossref","first-page":"E4016","DOI":"10.1073\/pnas.1309143110","article-title":"Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model","volume":"110","author":"Janezic","year":"2013","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"9","key":"10.1016\/j.jneumeth.2019.108532_bib0185","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1093\/hmg\/ddv016","article-title":"Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington\u2019s disease","volume":"24","author":"Jin","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0190","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.neubiorev.2004.10.006","article-title":"Meta-analysis of sex differences in rodent models of learning and memory: a review of behavioral and biological data","volume":"28","author":"Jonasson","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0195","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3389\/fnagi.2018.00172","article-title":"Sex differences in healthspan predict lifespan in the 3xTg-AD mouse model of Alzheimer\u2019s disease","volume":"10","author":"Kane","year":"2018","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0200","series-title":"A Spontaneous Point Mutation in the Mouse Gene Roundabout Homolog 3 Results in Impaired Balance 3. MGI Direct Data Submission","author":"Karst","year":"2011"},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0205","doi-asserted-by":"crossref","first-page":"591","DOI":"10.3233\/JAD-170805","article-title":"Age-related changes in the spatial frequency threshold of male and female 3xTg-AD mice using OptoMotry","volume":"62","author":"King","year":"2018","journal-title":"J. Alzheimer Dis."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0210","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.conb.2006.06.009","article-title":"Active sensation: insights from the rodent vibrissae sensorimotor system","volume":"16","author":"Kleinfeld","year":"2006","journal-title":"Curr. Opin. Neurobiol."},{"issue":"1","key":"10.1016\/j.jneumeth.2019.108532_bib0215","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1538\/expanim.58.19","article-title":"Direct experimental occlusion of the distal middle cerebral artery induces high reproducibility of brain ischemia in mice","volume":"58","author":"Kuraoka","year":"2009","journal-title":"Exp. Anim."},{"issue":"6","key":"10.1016\/j.jneumeth.2019.108532_bib0220","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1167\/iovs.12-9662","article-title":"The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL\/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes","volume":"53","author":"Mattapallil","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"8","key":"10.1016\/j.jneumeth.2019.108532_bib0225","doi-asserted-by":"crossref","first-page":"e23244","DOI":"10.1371\/journal.pone.0023244","article-title":"Optimised and rapid pre-clinical screening in the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS)","volume":"6","author":"Mead","year":"2011","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.jneumeth.2019.108532_bib0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049838","article-title":"Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington\u2019s disease: zQ175","volume":"7","author":"Menalled","year":"2012","journal-title":"PLoS One"},{"issue":"1581","key":"10.1016\/j.jneumeth.2019.108532_bib0235","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1098\/rstb.2011.0156","article-title":"Active vibrissal sensing in rodents and marsupials","volume":"366","author":"Mitchinson","year":"2011","journal-title":"Philos. Trans. Biol. Sci."},{"issue":"1613","key":"10.1016\/j.jneumeth.2019.108532_bib0240","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1098\/rspb.2006.0347","article-title":"Feedback control in active sensing: rat exploratory whisking is modulated by environmental contact","volume":"274","author":"Mitchinson","year":"2007","journal-title":"Proceedings of the Royal Society B: Biological Sciences"},{"issue":"9","key":"10.1016\/j.jneumeth.2019.108532_bib0245","doi-asserted-by":"crossref","first-page":"e1003236","DOI":"10.1371\/journal.pcbi.1003236","article-title":"Whisker movements reveal spatial attention: a unified computational model of active sensing control in the rat","volume":"9","author":"Mitchinson","year":"2013","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0250","first-page":"1","article-title":"Building a better mouse: one hundred years of genetics and biology","author":"Morse","year":"2007","journal-title":"The Mouse in Biomedical Research"},{"issue":"3","key":"10.1016\/j.jneumeth.2019.108532_bib0255","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.nbd.2008.11.015","article-title":"Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6\/2 mice","volume":"33","author":"Morton","year":"2009","journal-title":"Neurobiol. Dis."},{"issue":"18","key":"10.1016\/j.jneumeth.2019.108532_bib0260","doi-asserted-by":"crossref","first-page":"6183","DOI":"10.1523\/JNEUROSCI.0343-12.2012","article-title":"Neurotransmitter release at the thalamocortical synapse instructs barrel formation but not axon patterning in the somatosensory cortex","volume":"32","author":"Narboux-N\u00eame","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0265","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.brainres.2006.10.087","article-title":"Cerebral embolic ischemia in rats: correlation of stroke severity and functional deficit as important outcome parameter","volume":"1130","author":"Nedelmann","year":"2007","journal-title":"Brain Res."},{"issue":"40","key":"10.1016\/j.jneumeth.2019.108532_bib0270","doi-asserted-by":"crossref","first-page":"10129","DOI":"10.1523\/JNEUROSCI.1202-06.2006","article-title":"Intraneuronal \u03b2-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer\u2019s disease mutations: potential factors in amyloid plaque formation","volume":"26","author":"Oakley","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0275","article-title":"Age-related deterioration of motor function in male and female 5xFAD mice from 3-16 months of age","author":"O\u2019Leary","year":"2018","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0280","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.bbr.2017.09.009","article-title":"Motor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer\u2019s disease","volume":"337","author":"O\u2019Leary","year":"2018","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.jneumeth.2019.108532_bib0285","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/gbb.12370","article-title":"Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer\u2019s disease","volume":"16","author":"O\u2019leary","year":"2017","journal-title":"Genes Brain Behav."},{"issue":"6","key":"10.1016\/j.jneumeth.2019.108532_bib0290","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.brainresbull.2008.10.007","article-title":"The detection and measurement of locomotor deficits in a transgenic mouse model of Huntington\u2019s disease are task- and protocol-dependent: influence of non-motor factors on locomotor function","volume":"78","author":"Pallier","year":"2009","journal-title":"Brain Res. Bull."},{"issue":"1","key":"10.1016\/j.jneumeth.2019.108532_bib0295","first-page":"170","article-title":"Mouse models of human disease: An evolutionary perspective","volume":"2016","author":"Perlman","year":"2016","journal-title":"Evol. Med. Public Health"},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0300","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.neuron.2007.09.017","article-title":"The functional organization of the barrel cortex","volume":"56","author":"Petersen","year":"2007","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.jneumeth.2019.108532_bib0305","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bbr.2003.10.033","article-title":"The heterozygous reeler mouse: behavioural phenotype","volume":"153","author":"Podhorna","year":"2004","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0310","series-title":"Active Touch Sensing","author":"Prescott","year":"2011"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0315","doi-asserted-by":"crossref","first-page":"e23494","DOI":"10.7554\/eLife.23494","article-title":"A mutant with bilateral whisker to barrel inputs unveils somatosensory mapping rules in the cerebral cortex","volume":"6","author":"Renier","year":"2017","journal-title":"Elife"},{"issue":"3","key":"10.1016\/j.jneumeth.2019.108532_bib0320","doi-asserted-by":"crossref","first-page":"e1000325","DOI":"10.1371\/journal.pbio.1000325","article-title":"Genetic dissection of the function of hindbrain axonal commissures","volume":"8","author":"Renier","year":"2010","journal-title":"PLoS Biol."},{"issue":"11","key":"10.1016\/j.jneumeth.2019.108532_bib0325","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.1111\/j.1460-9568.2004.03783.x","article-title":"Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington\u2019s disease mutation","volume":"20","author":"Ribchester","year":"2004","journal-title":"Eur. J. Neurosci."},{"issue":"5","key":"10.1016\/j.jneumeth.2019.108532_bib0330","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/chemse\/bjw018","article-title":"Sex and genotype differences in odor detection in the 3\u00d7 Tg-AD and 5XFAD mouse models of Alzheimer\u2019s disease at 6 months of age","volume":"41","author":"Roddick","year":"2016","journal-title":"Chem. Senses"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0335","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.bbr.2014.04.038","article-title":"Olfactory delayed matching to sample performance in mice: sex differences in the 5XFAD mouse model of Alzheimer\u2019s disease","volume":"270","author":"Roddick","year":"2014","journal-title":"Behav. Brain Res."},{"issue":"3","key":"10.1016\/j.jneumeth.2019.108532_bib0340","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s12975-012-0234-1","article-title":"Distal occlusion of the middle cerebral artery in mice: are we ready to assess long-term functional outcome?","volume":"4","author":"Rosell","year":"2013","journal-title":"Transl. Stroke Res."},{"issue":"5","key":"10.1016\/j.jneumeth.2019.108532_bib0345","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0028-3908(00)00005-8","article-title":"CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury","volume":"39","author":"Schallert","year":"2000","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0350","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0065-3454(10)41007-4","article-title":"How many ways can mouse behavioral experiments go wrong? Confounding variables in mouse models of neurodegenerative diseases and how to control them","volume":"41","author":"Schellinck","year":"2010","journal-title":"Adv. Study Behav."},{"issue":"3","key":"10.1016\/j.jneumeth.2019.108532_bib0355","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1469-185X.2007.00016.x","article-title":"Mammalian evolution and biomedicine: new views from phylogeny","volume":"82","author":"Springer","year":"2007","journal-title":"Biol. Rev."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0360","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.bbr.2014.10.033","article-title":"Reference and working memory deficits in the 3xTg-AD mouse between 2 and 15-months of age: a cross-sectional study","volume":"278","author":"Stevens","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0365","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.bbr.2014.11.046","article-title":"Analysis of motor function in 6-month-old male and female 3xTg-AD mice","volume":"281","author":"Stover","year":"2015","journal-title":"Behav. Brain Res."},{"issue":"34","key":"10.1016\/j.jneumeth.2019.108532_bib0370","doi-asserted-by":"crossref","first-page":"8838","DOI":"10.1523\/JNEUROSCI.0581-06.2006","article-title":"Right\u2013left asymmetries in the whisking behavior of rats anticipate head movements","volume":"26","author":"Towal","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108532_bib0375","series-title":"The Rat Nervous System","first-page":"817","article-title":"CHAPTER 26 - trigeminal sensory system","author":"Waite","year":"2004"},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0380","first-page":"820","article-title":"Thalamocortical connections drive intracortical activation of functional columns in the mislaminated reeler somatosensory cortex","volume":"26","author":"Wagener","year":"2016","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.jneumeth.2019.108532_bib0385","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/nature01262","article-title":"Initial sequencing and comparative analysis of the mouse genome","volume":"420","author":"Waterston","year":"2002","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.jneumeth.2019.108532_bib0390","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.expneurol.2004.09.005","article-title":"Testing forelimb placing \u201cacross the midline\u201d reveals distinct, lesion-dependent patterns of recovery in rats","volume":"191","author":"Woodlee","year":"2005","journal-title":"Exp. Neurol."}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027019303899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027019303899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T11:03:46Z","timestamp":1778670226000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027019303899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":78,"alternative-id":["S0165027019303899"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2019.108532","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recommendations for measuring whisker movements and locomotion in mice with sensory, motor and cognitive deficits","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2019.108532","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108532"}}