{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T09:10:50Z","timestamp":1790327450428,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,12,20]],"date-time":"2020-12-20T00:00:00Z","timestamp":1608422400000},"content-version":"am","delay-in-days":323,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100006251","name":"Universit\u00e9 de Bordeaux","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006251","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.jneumeth.2019.108551","type":"journal-article","created":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T12:06:57Z","timestamp":1576498017000},"page":"108551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Models of hyperkinetic disorders in primates"],"prefix":"10.1016","volume":"332","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0410-4638","authenticated-orcid":false,"given":"Erwan","family":"Bezard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2019.108551_bib0005","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3000664","article-title":"Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson\u2019s disease","volume":"2","author":"Ahmed","year":"2010","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0010","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/978-1-4939-7825-0_14","article-title":"Nonhuman primate models of huntington\u2019s disease and their application in translational research","volume":"1780","author":"Aron Badin","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0015","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/0361-9230(83)90218-6","article-title":"Histochemical observations on rodent brain melanin","volume":"10","author":"Barden","year":"1983","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0020","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.pneurobio.2015.07.002","article-title":"Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson\u2019s disease","volume":"132","author":"Bastide","year":"2015","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0025","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/0014-4886(70)90189-5","article-title":"Effect of harmaline in monkeys with central nervous system lesions","volume":"28","author":"Battista","year":"1970","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0030","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/35086062","article-title":"Pathophysiology of levodopa-induced dyskinesia: Potential for new therapies","volume":"2","author":"Bezard","year":"2001","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0035","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/nm875","article-title":"Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function","volume":"9","author":"Bezard","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0040","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ejphar.2003.11.065","article-title":"Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque","volume":"485","author":"Bezard","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0045","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/mds.27121","article-title":"Tremor task force of the international P, movement disorder S. consensus statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society","volume":"33","author":"Bhatia","year":"2018","journal-title":"Mov. Disord."},{"issue":"Suppl 1","key":"10.1016\/j.jneumeth.2019.108551_bib0050","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1017\/S0317167100003309","article-title":"Antipsychotic drug-induced movement disorders","volume":"30","author":"Blanchet","year":"2003","journal-title":"Can. J. Neurol. Sci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0055","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1744-9081-8-12","article-title":"Relevance of animal models to human tardive dyskinesia","volume":"8","author":"Blanchet","year":"2012","journal-title":"Behav. Brain Funct."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0060","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1111\/j.1471-4159.2005.03515.x","article-title":"3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington\u2019s disease","volume":"95","author":"Brouillet","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0065","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/0306-4522(94)00431-4","article-title":"Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease","volume":"64","author":"Burns","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0070","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/nrn3475","article-title":"Power failure: why small sample size undermines the reliability of neuroscience","volume":"14","author":"Button","year":"2013","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0075","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.nlm.2015.06.012","article-title":"Why bother using non-human primate models of cognitive disorders in translational research?","volume":"124","author":"Camus","year":"2015","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0080","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/s41467-019-08858-y","article-title":"Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson\u2019s disease pathogenesis","volume":"10","author":"Carballo-Carbajal","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0085","article-title":"Progressive cognitive deficit, motor impairment and striatal pathology in a transgenic Huntington disease monkey model from infancy to adulthood","volume":"10","author":"Chan","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0090","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1471-2202-15-36","article-title":"A two years longitudinal study of a transgenic Huntington disease monkey","volume":"15","author":"Chan","year":"2014","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0095","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/gt.2017.84","article-title":"In utero delivery of rAAV2\/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson\u2019s disease","volume":"24","author":"Chansel-Debordeaux","year":"2017","journal-title":"Gene Ther."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0100","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3389\/fnagi.2014.00258","article-title":"Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?","volume":"6","author":"Charron","year":"2014","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0105","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0022-510X(87)90041-4","article-title":"Levodopa-induced dyskinesia and response fluctuations in primates rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)","volume":"78","author":"Clarke","year":"1987","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0306-4522(87)90322-8","article-title":"Primate models of dyskinesia: the experimental approach to the study of basal ganglia-related involuntary movement disorders","volume":"21","author":"Crossman","year":"1987","journal-title":"Neuroscience"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0115","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1017\/S0317167100037859","article-title":"MPTP-induced parkinsonism in the monkey: neurochemical pathology, complications of treatment and pathophysiological mechanisms","volume":"14","author":"Crossman","year":"1987","journal-title":"Can. J. Neurol. Sci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0120","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/srep00253","article-title":"Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques","volume":"2","author":"Dehay","year":"2012","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0125","doi-asserted-by":"crossref","first-page":"21824","DOI":"10.1073\/pnas.1012071107","article-title":"Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia","volume":"107","author":"Fasano","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0130","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1006\/exnr.1993.1006","article-title":"Excitotoxin lesions in primates as a model for Huntington\u2019s disease: histopathologic and neurochemical characterization","volume":"119","author":"Ferrante","year":"1993","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0135","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/nbt.1610","article-title":"Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN","volume":"28","author":"Foust","year":"2010","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0140","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1002\/mds.25133","article-title":"A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale","volume":"27","author":"Fox","year":"2012","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0145","doi-asserted-by":"crossref","first-page":"14338","DOI":"10.1523\/JNEUROSCI.4223-07.2007","article-title":"RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson\u2019s disease","volume":"27","author":"Gold","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0150","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1460-9568.2005.04196.x","article-title":"Levodopa-induced dyskinesia in MPTP-treated macaque is not dependent of the extent and pattern of the nigrostrial lesion","volume":"22","author":"Guigoni","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0155","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/BF00426838","article-title":"Haloperidol-induced tardive dyskinesia in monkeys","volume":"50","author":"Gunne","year":"1976","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0160","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/BF00433548","article-title":"A monitoring test for the liability of neuroleptic drugs to induce tardive dyskinesia","volume":"63","author":"Gunne","year":"1979","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0165","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0014-4886(90)90014-J","article-title":"A primate model of Huntington\u2019s disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon","volume":"108","author":"Hantraye","year":"1990","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0170","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3389\/neuro.09.031.2009","article-title":"The human brain in numbers: a linearly scaled-up primate brain","volume":"3","author":"Herculano-Houzel","year":"2009","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0175","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3389\/fnana.2014.00077","article-title":"Brain scaling in mammalian evolution as a consequence of concerted and mosaic changes in numbers of neurons and average neuronal cell size","volume":"8","author":"Herculano-Houzel","year":"2014","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0180","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/334345a0","article-title":"Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson\u2019s disease","volume":"334","author":"Hirsch","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0185","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.neuropharm.2012.06.012","article-title":"L-DOPA pharmacokinetics in the MPTP-lesioned macaque model of Parkinson\u2019s disease","volume":"63","author":"Huot","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0190","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1124\/pr.111.005678","article-title":"The pharmacology of L-DOPA-induced dyskinesia in Parkinson\u2019s disease","volume":"65","author":"Huot","year":"2013","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0195","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.neuroscience.2012.03.023","article-title":"Animal models of L-DOPA-induced dyskinesia: an update on the current options","volume":"211","author":"Iderberg","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0200","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1124\/jpet.110.166629","article-title":"Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson\u2019s disease","volume":"333","author":"Johnston","year":"2010","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2013.06.005","article-title":"TC-8831, a nicotinic acetylcholine receptor agonist, reduces l-DOPA-induced dyskinesia in the MPTP macaque","author":"Johnston","year":"2013","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0210","doi-asserted-by":"crossref","first-page":"7255","DOI":"10.1093\/hmg\/ddv425","article-title":"CRISPR\/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH","volume":"24","author":"Kang","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0215","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1002\/mds.23631","article-title":"The selective mu-opioid receptor antagonist ADL5510 reduces levodopa-induced dyskinesia without affecting antiparkinsonian action in MPTP-lesioned macaque model of Parkinson\u2019s disease","volume":"26","author":"Koprich","year":"2011","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0220","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.pnpbp.2012.12.008","article-title":"The effects of fast-off-D2 receptor antagonism on L-DOPA-induced dyskinesia and psychosis in parkinsonian macaques","volume":"43","author":"Koprich","year":"2013","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0225","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1017\/S0317167100046333","article-title":"Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): implications for treatment and the pathogenesis of Parkinson\u2019s disease","volume":"11","author":"Langston","year":"1984","journal-title":"Can. J. Neurol. Sci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0230","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1126\/science.6823561","article-title":"Chronic parkinsonism in human due to a product of meperidine analog synthesis","volume":"219","author":"Langston","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0235","first-page":"S79","article-title":"Investigating levodopa-induced dyskinesias in the Parkinsonian primate","volume":"47","author":"Langston","year":"2000","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2019.104484","article-title":"Longitudinal characterization of cognitive and motor deficits in an excitotoxic lesion model of striatal dysfunction in non-human primates","volume":"130","author":"Lavisse","year":"2019","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0245","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.stem.2014.01.018","article-title":"TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys","volume":"14","author":"Liu","year":"2014","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0250","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/nature16533","article-title":"Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2","volume":"530","author":"Liu","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0255","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1523\/JNEUROSCI.4392-12.2013","article-title":"Evolutionarily novel functional networks in the human brain?","volume":"33","author":"Mantini","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0260","first-page":"256","article-title":"Pigmentation in the nucleus substantiae nigrae of mammals","volume":"95","author":"Marsden","year":"1961","journal-title":"J. Anat."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0265","article-title":"Modeling dyskinesia in animal models of Parkinson disease","author":"Morin","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0270","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.cell.2014.01.027","article-title":"Generation of gene-modified cynomolgus monkey via Cas9\/RNA-mediated gene targeting in one-cell embryos","volume":"156","author":"Niu","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0275","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1038\/sj.mt.6300185","article-title":"Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates","volume":"15","author":"Palfi","year":"2007","journal-title":"Mol. Ther."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0280","doi-asserted-by":"crossref","first-page":"587","DOI":"10.5334\/tohm.440","article-title":"Animal models of tremor: relevance to human tremor disorders","volume":"8","author":"Pan","year":"2018","journal-title":"Tremor Hyperkinet. Mov. (N Y)"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0285","doi-asserted-by":"crossref","first-page":"3730","DOI":"10.1038\/srep03730","article-title":"L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum","volume":"4","author":"Porras","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0290","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a009308","article-title":"Modeling Parkinson\u2019s disease in primates: the MPTP model","volume":"2","author":"Porras","year":"2012","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0295","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.neuron.2014.06.003","article-title":"Basic neuroscience research with nonhuman primates: a small but indispensable component of biomedical research","volume":"82","author":"Roelfsema","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0300","first-page":"137","article-title":"Behavioral and morphological comparison of two nonhuman primate models of Huntington\u2019s disease","volume":"50","author":"Roitberg","year":"2002","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0305","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.nbd.2010.05.001","article-title":"A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys","volume":"39","author":"Rylander","year":"2010","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0310","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00702-017-1803-y","article-title":"Progress in developing transgenic monkey model for Huntington\u2019s disease","volume":"125","author":"Snyder","year":"2018","journal-title":"J. Neural Transm. (Vienna)"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0315","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1080\/15548627.2019.1659621","article-title":"Intracellular crowding by age-dependent neuromelanin accumulation disrupts neuronal proteostasis and triggers Parkinson disease pathology","volume":"15","author":"Vila","year":"2019","journal-title":"Autophagy"},{"key":"10.1016\/j.jneumeth.2019.108551_bib0320","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nn.2956","article-title":"Cross-species studies of orbitofrontal cortex and value-based decision-making","volume":"15","author":"Wallis","year":"2011","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jneumeth.2019.108551_bib0325","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/nature06975","article-title":"Towards a transgenic model of Huntington\u2019s disease in a non-human primate","volume":"453","author":"Yang","year":"2008","journal-title":"Nature"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016502701930408X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016502701930408X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:52:56Z","timestamp":1759020776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016502701930408X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":65,"alternative-id":["S016502701930408X"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2019.108551","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Models of hyperkinetic disorders in primates","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2019.108551","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108551"}}