{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T08:41:51Z","timestamp":1792485711913,"version":"4.5.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072773"],"award-info":[{"award-number":["82072773"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["YJ202373"],"award-info":[{"award-number":["YJ202373"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012542","name":"Sichuan Provincial Science and Technology Support Program","doi-asserted-by":"publisher","award":["2023YFG0127"],"award-info":[{"award-number":["2023YFG0127"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroscience Methods"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.jneumeth.2026.110898","type":"journal-article","created":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T06:32:36Z","timestamp":1788676356000},"page":"110898","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Toward intraoperative glioma localization: Exploring the relationship between tumor invasion depth and electrocorticography signals"],"prefix":"10.1016","volume":"437","author":[{"given":"Wenyu","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianming","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Quan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayuan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneumeth.2026.110898_bib1","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2108959118","article-title":"Functional alterations in cortical processing of speech in glioma-infiltrated cortex","volume":"118","author":"Aabedi","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jneumeth.2026.110898_bib2","author":"Ambati","year":"2025","journal-title":"Electro Detect. Speech Netw. glioma-infiltrated cortex. bioRxiv Prepr."},{"key":"10.1016\/j.jneumeth.2026.110898_bib3","doi-asserted-by":"crossref","first-page":"3046","DOI":"10.1152\/jn.91143.2008","article-title":"EEG generator--a model of potentials in a volume conductor","volume":"102","author":"Avitan","year":"2009","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib4","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s11060-021-03862-z","article-title":"Surgical strategies for older patients with glioblastoma","volume":"155","author":"Barak","year":"2021","journal-title":"J. Neurooncol"},{"key":"10.1016\/j.jneumeth.2026.110898_bib5","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0090-3019(01)00351-2","article-title":"Acetylcholinesterase and butyrylcholinesterase histochemical activities and tumor cell growth in several brain tumors","volume":"55","author":"Barbosa","year":"2001","journal-title":"Surg. Neurol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib6","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1038\/nm.2453","article-title":"Glutamate release by primary brain tumors induces epileptic activity","volume":"17","author":"Buckingham","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneumeth.2026.110898_bib7","unstructured":"Chetty S., Venayagamoorthy G.K. editors. A Neural Network Based Detection of Brain Tumours Using Electroencephalography; 2002."},{"key":"10.1016\/j.jneumeth.2026.110898_bib8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1006\/abbi.2001.2540","article-title":"Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: possible functional consequences","volume":"394","author":"Cobbs","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jneumeth.2026.110898_bib9","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/j.ccell.2024.08.009","article-title":"Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma","volume":"42","author":"Curry","year":"2024","journal-title":"Cancer Cell."},{"key":"10.1016\/j.jneumeth.2026.110898_bib10","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1200\/JCO.2011.38.4818","article-title":"Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis","volume":"30","author":"De Witt Hamer","year":"2012","journal-title":"J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib11","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s11060-020-03520-w","article-title":"Awake craniotomy for gliomas involving motor-related areas: classification and function recovery","volume":"148","author":"Fang","year":"2020","journal-title":"J. Neuro-Oncol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib12","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.media.2016.08.007","article-title":"Brain shift in neuronavigation of brain tumors: a review","volume":"35","author":"Gerard","year":"2017","journal-title":"Med. Image Anal."},{"key":"10.1016\/j.jneumeth.2026.110898_bib13","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s11060-020-03482-z","article-title":"Awake glioma surgery: technical evolution and nuances","volume":"147","author":"Gogos","year":"2020","journal-title":"J. Neurooncol"},{"key":"10.1016\/j.jneumeth.2026.110898_bib14","first-page":"252","article-title":"Glioblastoma: defining tumor niches. trends can","volume":"1","author":"Hambardzumyan","year":"2015","journal-title":"cer"},{"key":"10.1016\/j.jneumeth.2026.110898_bib15","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1055\/s-0043-1776766","article-title":"Surgical management and advances in the treatment of Glioma","volume":"43","author":"Hardigan","year":"2023","journal-title":"Semin. Neurol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib16","article-title":"Full-course resection control strategy in glioma surgery using both intraoperative ultrasound and intraoperative MRI","volume":"12","author":"Hou","year":"2022","journal-title":"Front. Oncol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib17","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nrneurol.2016.26","article-title":"Seizures and gliomas--towards a single therapeutic approach","volume":"12","author":"Huberfeld","year":"2016","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib18","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.brainres.2008.06.029","article-title":"Novel modes of rhythmic burst firing at cognitively-relevant frequencies in thalamocortical neurons","volume":"1235","author":"Hughes","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.jneumeth.2026.110898_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.649797","article-title":"Intraoperative b-mode ultrasound guided surgery and the extent of glioblastoma resection: a randomized controlled trial","volume":"11","author":"Incekara","year":"2021","journal-title":"Front. Oncol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib20","series-title":"Magnetoencephalography: From Signals to Dynamic Cortical Networks Cham","first-page":"1","article-title":"Human Brain Oscillations: From Physiological Mechanisms to Analysis and Cognition","author":"Jensen","year":"2019"},{"key":"10.1016\/j.jneumeth.2026.110898_bib21","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/j.clinph.2004.01.001","article-title":"EEG dynamics in patients with Alzheimer's disease","volume":"115","author":"Jeong","year":"2004","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib22","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.canlet.2020.10.050","article-title":"Clinical practice guidelines for the management of adult diffuse gliomas","volume":"499","author":"Jiang","year":"2021","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jneumeth.2026.110898_bib23","article-title":"Effect of anesthesia on electrocorticography for localization of epileptic focus: Literature review and future directions","volume":"118","author":"Kacar Bayram","year":"2021","journal-title":"Epilepsy Behav. E B"},{"key":"10.1016\/j.jneumeth.2026.110898_bib24","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/nrn3578","article-title":"Neuroscience thinks big (and collaboratively)","volume":"14","author":"Kandel","year":"2013","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.jneumeth.2026.110898_bib25","doi-asserted-by":"crossref","unstructured":"Karameh F N, Dahleh M A. Automated classification of EEG signals in brain tumor diagnostics[C]\/\/proceedings of the 2000 American control conference. ACC (IEEE cat. No. 00CH36334). IEEE, 2000, 6: 4169-4173.","DOI":"10.1109\/ACC.2000.877006"},{"key":"10.1016\/j.jneumeth.2026.110898_bib26","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.bbamem.2005.07.010","article-title":"Temporal regulation of connexin phosphorylation in embryonic and adult tissues","volume":"1719","author":"King","year":"2005","journal-title":"Biochim. Et. Biophys. Acta"},{"key":"10.1016\/j.jneumeth.2026.110898_bib27","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s11517-019-02091-x","article-title":"Intelligent autonomous treatment of bedwetting using non-invasive wearable advanced mechatronics systems and MEMS sensors: intelligent autonomous bladder monitoring to treat NE","volume":"58","author":"Kuru","year":"2020","journal-title":"Med. Biol. Eng. Comput."},{"key":"10.1016\/j.jneumeth.2026.110898_bib28","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1007\/s10143-023-02058-5","article-title":"Diffusion tensor imaging versus intraoperative subcortical mapping for glioma resection: a systematic review and meta-analysis","volume":"46","author":"Li","year":"2023","journal-title":"Neurosurg. Rev."},{"key":"10.1016\/j.jneumeth.2026.110898_bib29","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.tics.2024.03.010","article-title":"Beta: bursts of cognition","volume":"28","author":"Lundqvist","year":"2024","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.jneumeth.2026.110898_bib30","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.wneu.2016.05.007","article-title":"Intraoperative ultrasound-guided resection of gliomas: a meta-analysis and review of the literature","volume":"92","author":"Mahboob","year":"2016","journal-title":"World Neurosurg."},{"key":"10.1016\/j.jneumeth.2026.110898_bib31","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s11060-009-9990-5","article-title":"vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines","volume":"97","author":"Marcus","year":"2009","journal-title":"J. Neuro-Oncol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib32","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.1038\/s41467-024-48757-5","article-title":"Glioblastoma disrupts cortical network activity at multiple spatial and temporal scales","volume":"15","author":"Meyer","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jneumeth.2026.110898_bib33","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/ons\/opz203","article-title":"Navigated Intraoperative 2-dimensional ultrasound in high-grade glioma surgery: impact on extent of resection and patient outcome","volume":"18","author":"Moiraghi","year":"2020","journal-title":"Oper. Neurosurg. (Hagerstown Md)"},{"key":"10.1016\/j.jneumeth.2026.110898_bib34","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.1007\/s00018-018-2837-5","article-title":"Involvement of extrasynaptic glutamate in physiological and pathophysiological changes of neuronal excitability","volume":"75","author":"P\u00e1l","year":"2018","journal-title":"Cell. Mol. life Sci. CMLS"},{"key":"10.1016\/j.jneumeth.2026.110898_bib35","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/s10143-024-02354-8","article-title":"Intraoperative ultrasound for surgical resection of high-grade glioma and glioblastoma: a meta-analysis of 732 patients","volume":"47","author":"Pichardo-Rojas","year":"2024","journal-title":"Neurosurg. Rev."},{"issue":"4","key":"10.1016\/j.jneumeth.2026.110898_bib36","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00701-003-0204-1","article-title":"Course of brain shift during microsurgical resection of supratentorial cerebral lesions: limits of conventional neuronavigation","volume":"146","author":"Reinges","year":"2004","journal-title":"Acta Neurochir."},{"key":"10.1016\/j.jneumeth.2026.110898_bib37","doi-asserted-by":"crossref","first-page":"6591","DOI":"10.1073\/pnas.90.14.6591","article-title":"Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity","volume":"90","author":"Rothstein","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jneumeth.2026.110898_bib38","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s11060-018-2785-9","article-title":"High expression of cystine-glutamate antiporter xCT (SLC7A11) is an independent biomarker for epileptic seizures at diagnosis in glioma","volume":"138","author":"S\u00f8rensen","year":"2018","journal-title":"J. Neurooncol"},{"key":"10.1016\/j.jneumeth.2026.110898_bib39","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s11517-019-01980-5","article-title":"Early glioma is associated with abnormal electrical events in cortical cultures","volume":"57","author":"Savarra","year":"2019","journal-title":"Med. Biol. Eng. Comput."},{"key":"10.1016\/j.jneumeth.2026.110898_bib40","first-page":"1","article-title":"Evaluation and Diagnosis of Brain Diseases based on Non-invasive BCI","volume":"2021","author":"Song","year":"2021","journal-title":"2021 9th Int. Winter Conf. Brain-Comput. Interface (BCI)"},{"key":"10.1016\/j.jneumeth.2026.110898_bib41","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1038\/nm0901-1010","article-title":"Glutamate release promotes growth of malignant gliomas","volume":"7","author":"Takano","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneumeth.2026.110898_bib42","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.nic.2022.04.008","article-title":"Anatomy of the Cerebral Cortex, Lobes, and Cerebellum","volume":"32","author":"Vachha","year":"2022","journal-title":"Neuroimaging Clin. North. Am."},{"key":"10.1016\/j.jneumeth.2026.110898_bib43","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1016\/j.clinph.2012.04.012","article-title":"Slowing of M1 oscillations in brain tumor patients in resting state and during movement","volume":"123","author":"van Wijk","year":"2012","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.jneumeth.2026.110898_bib44","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.canlet.2021.11.020","article-title":"Glioma invasion along white matter tracts: a dilemma for neurosurgeons","volume":"526","author":"Wang","year":"2022","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jneumeth.2026.110898_bib45","first-page":"1","article-title":"Exploration of brain tumor localization with high-density electrocorticography","volume":"2024","author":"Wu","year":"2024","journal-title":"Annu. Int. Conf. IEEE Eng. Med. Biol. Soc. IEEE Eng. Med. Biol. Soc. Annu. Int. Conf."},{"key":"10.1016\/j.jneumeth.2026.110898_bib46","doi-asserted-by":"crossref","first-page":"e532","DOI":"10.1016\/j.wneu.2022.06.094","article-title":"The intraoperative utilization of multimodalities could improve the prognosis of adult glioblastoma: a single-center observational study","volume":"165","author":"Xiong","year":"2022","journal-title":"World Neurosurg."},{"key":"10.1016\/j.jneumeth.2026.110898_bib47","first-page":"4383","article-title":"Glioma cells release excitotoxic concentrations of glutamate","volume":"59","author":"Ye","year":"1999","journal-title":"Cancer Res."},{"key":"10.1016\/j.jneumeth.2026.110898_bib48","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s11060-024-04577-7","article-title":"The relationship between pathological brain activity and functional network connectivity in glioma patients","volume":"166","author":"Zimmermann","year":"2024","journal-title":"J. Neurooncol"}],"container-title":["Journal of Neuroscience Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027026002281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165027026002281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T08:29:44Z","timestamp":1792484984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165027026002281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":48,"alternative-id":["S0165027026002281"],"URL":"https:\/\/doi.org\/10.1016\/j.jneumeth.2026.110898","relation":{},"ISSN":["0165-0270"],"issn-type":[{"value":"0165-0270","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Toward intraoperative glioma localization: Exploring the relationship between tumor invasion depth and electrocorticography signals","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroscience Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneumeth.2026.110898","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110898"}}