{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T08:37:34Z","timestamp":1790411854028,"version":"4.1.0"},"reference-count":11,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jni-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimmunology"],"published-print":{"date-parts":[[2004,2]]},"DOI":"10.1016\/j.jneuroim.2003.10.027","type":"journal-article","created":{"date-parts":[[2003,12,9]],"date-time":"2003-12-09T06:55:53Z","timestamp":1070952953000},"page":"127-130","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Cannabinoid-mediated exacerbation of brain infection by opportunistic amebae"],"prefix":"10.1016","volume":"147","author":[{"given":"Guy A.","family":"Cabral","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine","family":"Marciano-Cabral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneuroim.2003.10.027_BIB1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3181\/00379727-199-43330","article-title":"Enhanced growth of Legionella pneumophila in tetrahydrocannabinol-treated macrophages","volume":"199","author":"Arata","year":"1992","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB2","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0165-5728(97)00227-0","article-title":"Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease","volume":"83","author":"Cabral","year":"1998","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB3","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/978-1-4684-5925-8_10","article-title":"Effects of marijuana on macrophage function","volume":"288","author":"Cabral","year":"1991","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB4","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1093\/infdis\/169.5.1177-a","article-title":"Resistance to Legionella pneumophila suppressed by the marijuana component, tetrahydrocannabinol","volume":"169","author":"Klein","year":"1994","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1550-7408.2000.tb00007.x","article-title":"The increasing importance of Acanthamoeba infections","volume":"47","author":"Marciano-Cabral","year":"2000","journal-title":"J. Eukaryot. Microbiol."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB6","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1750-3639.1997.tb01076.x","article-title":"Free-living, amphizoic and opportunistic amebas","volume":"7","author":"Martinez","year":"1997","journal-title":"Brain Pathol."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB7","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1001\/archderm.1995.01690230069011","article-title":"Disseminated acanthamebiasis in patients with AIDS. A report of five cases and a review of the literature","volume":"131","author":"Murakawa","year":"1995","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB8","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/(SICI)1098-1136(20000101)29:1<58::AID-GLIA6>3.0.CO;2-W","article-title":"Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells","volume":"29","author":"Puffenbarger","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB9","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1128\/iai.42.2.645-652.1983","article-title":"Host resistance of mice to Naegleria fowleri infections","volume":"42","author":"Reilly","year":"1983","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB10","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0192-0561(91)90011-U","article-title":"Delta-9-tetrahydrocannabinol augments murine retroviral induced immunosuppression and infection","volume":"13","author":"Specter","year":"1991","journal-title":"Int. J. Immunopharmacol."},{"key":"10.1016\/j.jneuroim.2003.10.027_BIB11","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/S0022-3565(24)38093-0","article-title":"The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells","volume":"288","author":"Waksman","year":"1999","journal-title":"J. Pharmacol. Exp. Ther."}],"container-title":["Journal of Neuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572803004508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572803004508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T07:58:02Z","timestamp":1759046282000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165572803004508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2]]},"references-count":11,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["S0165572803004508"],"URL":"https:\/\/doi.org\/10.1016\/j.jneuroim.2003.10.027","relation":{},"ISSN":["0165-5728"],"issn-type":[{"value":"0165-5728","type":"print"}],"subject":[],"published":{"date-parts":[[2004,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cannabinoid-mediated exacerbation of brain infection by opportunistic amebae","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroimmunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneuroim.2003.10.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}