{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T01:47:46Z","timestamp":1788313666765,"version":"build-2803163510"},"reference-count":84,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jni-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimmunology"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.jneuroim.2010.05.003","type":"journal-article","created":{"date-parts":[[2010,6,29]],"date-time":"2010-06-29T04:24:07Z","timestamp":1277785447000},"page":"28-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["TNF-\u03b1-dependent regulation of CXCR3 expression modulates neuronal survival during West Nile virus encephalitis"],"prefix":"10.1016","volume":"224","author":[{"given":"Bo","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jigisha","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Croyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Diamond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn S.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneuroim.2010.05.003_bib1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1091\/mbc.9.3.561","article-title":"The Ras\/Rac1\/Cdc42\/SEK\/JNK\/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes","volume":"9","author":"Auer","year":"1998","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib2","first-page":"247","article-title":"Brain-derived neurotrophic factor is neuroprotective against human immunodeficiency virus-1 envelope proteins","volume":"1053","author":"Bachis","year":"2005","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib3","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1128\/JVI.78.4.1739-1750.2004","article-title":"Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells","volume":"78","author":"Bergmann","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib4","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1126\/science.1059742","article-title":"Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons","volume":"293","author":"Binder","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib5","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1097\/01.WCB.0000090080.64176.44","article-title":"Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo","volume":"23","author":"Boche","year":"2003","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib6","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/nm0796-788","article-title":"Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors","volume":"2","author":"Bruce","year":"1996","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0165-5728(98)00190-8","article-title":"Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD","volume":"93","author":"Bruce-Keller","year":"1999","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib8","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1038\/sj.bjc.6605078","article-title":"Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism","volume":"100","author":"Cambien","year":"2009","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib9","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S1473-3099(02)00368-7","article-title":"West Nile virus","volume":"2","author":"Campbell","year":"2002","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib10","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.micpath.2007.07.001","article-title":"Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity","volume":"44","author":"Carpenter","year":"2008","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib11","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1080\/13550280500384982","article-title":"Differential responses of human brain cells to West Nile virus infection","volume":"11","author":"Cheeran","year":"2005","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib12","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0896-6273(94)90159-7","article-title":"Tumor necrosis factors protect neurons against metabolic\u2013excitotoxic insults and promote maintenance of calcium homeostasis","volume":"12","author":"Cheng","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib13","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0306-4522(00)00024-5","article-title":"Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons","volume":"97","author":"Coughlan","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib14","doi-asserted-by":"crossref","first-page":"e106","DOI":"10.1371\/journal.ppat.0030106","article-title":"Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms","volume":"3","author":"Daffis","year":"2007","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib15","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1111\/j.1471-4159.2008.05511.x","article-title":"Japanese encephalitis virus infects neural progenitor cells and decreases their proliferation","volume":"106","author":"Das","year":"2008","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib16","doi-asserted-by":"crossref","first-page":"9509","DOI":"10.1158\/0008-5472.CAN-05-4345","article-title":"Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer","volume":"66","author":"Datta","year":"2006","journal-title":"Cancer Res."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib17","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1128\/JVI.77.4.2578-2586.2003","article-title":"B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus","volume":"77","author":"Diamond","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib18","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1111\/j.1471-4159.2008.05701.x","article-title":"TNF-alpha-mediates neuroprotection against glutamate-induced excitotoxicity via NF-kappaB-dependent up-regulation of K2.2 channels","volume":"107","author":"Dolga","year":"2008","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib19","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0165-5728(97)00009-X","article-title":"Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia","volume":"75","author":"Dopp","year":"1997","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib20","doi-asserted-by":"crossref","first-page":"6234","DOI":"10.4049\/jimmunol.173.10.6234","article-title":"Identification and partial characterization of a variant of human CXCR3 generated by posttranscriptional exon skipping","volume":"173","author":"Ehlert","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib21","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1245\/ASO.2006.03.038","article-title":"Interferon gamma-inducible protein 10 selectively inhibits proliferation and induces apoptosis in endothelial cells","volume":"13","author":"Feldman","year":"2006","journal-title":"Ann. Surg. Oncol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib22","doi-asserted-by":"crossref","first-page":"RC216","DOI":"10.1523\/JNEUROSCI.22-07-j0001.2002","article-title":"Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2","volume":"22","author":"Fontaine","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib23","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1046\/j.1471-4159.1998.70051876.x","article-title":"The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA\/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons","volume":"70","author":"Furukawa","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib24","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/glia.20474","article-title":"Proinflammatory mediators released by activated microglia induces neuronal death in Japanese encephalitis","volume":"55","author":"Ghoshal","year":"2007","journal-title":"Glia"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib25","first-page":"1489","article-title":"CXCR3 and its binding chemokines in myeloma cells: expression of isoforms and potential relationships with myeloma cell proliferation and survival","volume":"91","author":"Giuliani","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib26","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1084\/jem.20042530","article-title":"Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection","volume":"202","author":"Glass","year":"2005","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib27","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1365-2990.2001.00312.x","article-title":"CXCR3 expression in human central nervous system diseases","volume":"27","author":"Goldberg","year":"2001","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib28","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1038\/nm1202-1363","article-title":"The many faces of tumor necrosis factor in stroke","volume":"8","author":"Hallenbeck","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib29","doi-asserted-by":"crossref","first-page":"8813","DOI":"10.4049\/jimmunol.177.12.8813","article-title":"The expression and possible roles of chemokine CXCL11 and its receptor CXCR3 in the human endometrium","volume":"177","author":"Hirota","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib30","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/13550280600758341","article-title":"Temporal analyses of the neuropathogenesis of a West Nile virus infection in mice","volume":"12","author":"Hunsperger","year":"2006","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib31","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.2353\/ajpath.2008.080528","article-title":"Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice","volume":"173","author":"Janelsins","year":"2008","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib32","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/sj.cdd.4402006","article-title":"HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection","volume":"14","author":"Kaul","year":"2007","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib33","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0042-6822(03)00110-7","article-title":"Extensive immune-mediated hippocampal damage in mice surviving infection with neuroadapted Sindbis virus","volume":"311","author":"Kimura","year":"2003","journal-title":"Virology"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib34","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1242\/dev.128.11.1971","article-title":"SDF-1 alpha induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells","volume":"128","author":"Klein","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib35","doi-asserted-by":"crossref","first-page":"11457","DOI":"10.1128\/JVI.79.17.11457-11466.2005","article-title":"Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis","volume":"79","author":"Klein","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib36","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0165-5728(98)00273-2","article-title":"Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment","volume":"95","author":"Knoblach","year":"1999","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib37","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1006\/viro.1999.9734","article-title":"Neuronal expression of NOS-1 is required for host recovery from viral encephalitis","volume":"258","author":"Komatsu","year":"1999","journal-title":"Virology"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib38","first-page":"413","article-title":"Immune evasion, a critical strategy for rabies virus","volume":"131","author":"Lafon","year":"2008","journal-title":"Dev. Biol. Basel"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib39","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1084\/jem.20021897","article-title":"An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4","volume":"197","author":"Lasagni","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib40","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/978-1-4615-1899-0_24","article-title":"The protective role of cytotoxic T cells and interferon against coronavirus invasion of the brain","volume":"380","author":"Lavi","year":"1995","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib41","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.4049\/jimmunol.177.6.3644","article-title":"Different neurotropic pathogens elicit neurotoxic CCR9- or neurosupportive CXCR3-expressing microglia","volume":"177","author":"Li","year":"2006","journal-title":"J. Immunol."},{"issue":"Pt 3","key":"10.1016\/j.jneuroim.2010.05.003_bib42","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1099\/0022-1317-70-3-565","article-title":"Identification of cytolytic lymphocytes in West Nile virus-infected murine central nervous system","volume":"70","author":"Liu","year":"1989","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib43","doi-asserted-by":"crossref","first-page":"12036","DOI":"10.1016\/S0021-9258(18)37889-X","article-title":"Molecular and biochemical characterization of a novel gamma-interferon-inducible protein","volume":"263","author":"Luster","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib44","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1097\/00001756-200409150-00010","article-title":"BDNF down-regulates the caspase 3 pathway in injured geniculo-cortical neurones","volume":"15","author":"Madeddu","year":"2004","journal-title":"NeuroReport"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib45","doi-asserted-by":"crossref","first-page":"32869","DOI":"10.1074\/jbc.M311766200","article-title":"Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway","volume":"279","author":"Marchetti","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib46","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.pediatrneurol.2007.08.008","article-title":"Reversible splenial lesion in influenza virus encephalopathy","volume":"37","author":"Matsubara","year":"2007","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib47","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/(SICI)1097-4547(19970915)49:6<681::AID-JNR3>3.0.CO;2-3","article-title":"Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration","volume":"49","author":"Mattson","year":"1997","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib48","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jneuroim.2004.07.009","article-title":"The chemokine CXCL10 modulates excitatory activity and intracellular calcium signaling in cultured hippocampal neurons","volume":"156","author":"Nelson","year":"2004","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib49","first-page":"861","article-title":"Tumor necrosis factor-alpha induces cell type and tissue-specific expression of chemoattractant cytokines in vivo","volume":"142","author":"Ohmori","year":"1993","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib50","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/nm1240","article-title":"Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus","volume":"11","author":"Oliphant","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib51","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1708-8305.2007.00134.x","article-title":"Japanese encephalitis for a reference to international travelers","volume":"14","author":"Oya","year":"2007","journal-title":"J. Travel Med."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib52","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1128\/JVI.74.5.2447-2450.2000","article-title":"Contributions of Fas\u2013Fas ligand interactions to the pathogenesis of mouse hepatitis virus in the central nervous system","volume":"74","author":"Parra","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib53","doi-asserted-by":"crossref","first-page":"5701","DOI":"10.1128\/JVI.76.11.5701-5710.2002","article-title":"Langat flavivirus protease NS3 binds caspase-8 and induces apoptosis","volume":"76","author":"Prikhod'ko","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib54","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.virol.2005.08.043","article-title":"Host cell killing by the West Nile Virus NS2B-NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway","volume":"345","author":"Ramanathan","year":"2006","journal-title":"Virology"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib55","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1097\/TP.0b013e31819574e9","article-title":"CXCR3 antagonism impairs the development of donor-reactive, IFN-gamma-producing effectors and prolongs allograft survival","volume":"87","author":"Rosenblum","year":"2009","journal-title":"Transplantation"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib56","doi-asserted-by":"crossref","first-page":"4515","DOI":"10.1128\/JVI.72.5.4515-4519.1998","article-title":"Theiler's virus infection of perforin-deficient mice","volume":"72","author":"Rossi","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib57","doi-asserted-by":"crossref","first-page":"13350","DOI":"10.1128\/JVI.79.21.13350-13361.2005","article-title":"Alpha\/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival","volume":"79","author":"Samuel","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib58","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1128\/JVI.02311-06","article-title":"Caspase 3-dependent cell death of neurons contributes to the pathogenesis of West Nile virus encephalitis","volume":"81","author":"Samuel","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib59","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1161\/CIRCRESAHA.108.182683","article-title":"Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1","volume":"104","author":"Schwarz","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib60","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1001\/jama.290.4.511","article-title":"Neurologic manifestations and outcome of West Nile virus infection","volume":"290","author":"Sejvar","year":"2003","journal-title":"Jama"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib61","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1099\/vir.0.19022-0","article-title":"Dengue virus type 2 NS3 protease and NS2B-NS3 protease precursor induce apoptosis","volume":"84","author":"Shafee","year":"2003","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib62","doi-asserted-by":"crossref","first-page":"8312","DOI":"10.1128\/JVI.78.15.8312-8321.2004","article-title":"Role of CD8+ T cells in control of West Nile virus infection","volume":"78","author":"Shrestha","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib63","doi-asserted-by":"crossref","first-page":"13203","DOI":"10.1128\/JVI.77.24.13203-13213.2003","article-title":"Infection and injury of neurons by West Nile encephalitis virus","volume":"77","author":"Shrestha","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib64","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1128\/JVI.80.1.119-129.2006","article-title":"CD8+ T cells require perforin to clear West Nile virus from infected neurons","volume":"80","author":"Shrestha","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib65","doi-asserted-by":"crossref","first-page":"5338","DOI":"10.1128\/JVI.00274-06","article-title":"Gamma interferon plays a crucial early antiviral role in protection against West Nile virus infection","volume":"80","author":"Shrestha","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib66","doi-asserted-by":"crossref","first-page":"8956","DOI":"10.1128\/JVI.01118-08","article-title":"Tumor necrosis factor alpha protects against lethal West Nile virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system","volume":"82","author":"Shrestha","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib67","doi-asserted-by":"crossref","first-page":"9801","DOI":"10.1128\/JVI.00941-07","article-title":"CD40\u2013CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against West Nile Virus Encephalitis","volume":"81","author":"Sitati","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib68","doi-asserted-by":"crossref","first-page":"4162","DOI":"10.1128\/JVI.76.9.4162-4171.2002","article-title":"Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response","volume":"76","author":"Su","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib69","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/S0002-9440(10)63714-5","article-title":"Neuronal apoptosis is mediated by CXCL10 overexpression in simian human immunodeficiency virus encephalitis","volume":"164","author":"Sui","year":"2004","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib70","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1111\/j.1460-9568.2006.04631.x","article-title":"CXCL10-induced cell death in neurons: role of calcium dysregulation","volume":"23","author":"Sui","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib71","doi-asserted-by":"crossref","first-page":"8531","DOI":"10.1074\/jbc.274.13.8531","article-title":"Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons","volume":"274","author":"Tamatani","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib72","doi-asserted-by":"crossref","first-page":"6633","DOI":"10.1523\/JNEUROSCI.1091-07.2007","article-title":"FLIP(L) protects neurons against in vivo ischemia and in vitro glucose deprivation-induced cell death","volume":"27","author":"Taoufik","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib73","doi-asserted-by":"crossref","first-page":"6185","DOI":"10.1073\/pnas.0801447105","article-title":"TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury","volume":"105","author":"Taoufik","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib74","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.brainres.2003.10.029","article-title":"Role of tumor necrosis factor receptor-1 in the death of retinal ganglion cells following optic nerve crush injury in mice","volume":"996","author":"Tezel","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib75","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.4049\/jimmunol.164.3.1333","article-title":"Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system","volume":"164","author":"Tong","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib76","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1002\/cne.21229","article-title":"Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain","volume":"500","author":"Tran","year":"2007","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib77","doi-asserted-by":"crossref","first-page":"7701","DOI":"10.1158\/0008-5472.CAN-06-0709","article-title":"Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic breast cancer","volume":"66","author":"Walser","year":"2006","journal-title":"Cancer Res."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib78","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1096\/fj.06-5850fje","article-title":"Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo","volume":"20","author":"Weiss","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib79","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/cmdc.200700365","article-title":"Towards small-molecule CXCR3 ligands with clinical potential","volume":"3","author":"Wijtmans","year":"2008","journal-title":"ChemMedChem"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib80","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0165-5728(00)00285-X","article-title":"Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1\/2 activation and role in Alzheimer's disease","volume":"108","author":"Xia","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib81","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.3201\/eid0812.020224","article-title":"Induction of inflammation by West Nile virus capsid through the caspase-9 apoptotic pathway","volume":"8","author":"Yang","year":"2002","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib82","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0028-3908(01)00174-5","article-title":"Suppressive effects of phosphodiesterase type IV inhibitors on rat cultured microglial cells: comparison with other types of cAMP-elevating agents","volume":"42","author":"Zhang","year":"2002","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jneuroim.2010.05.003_bib83","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.4049\/jimmunol.180.4.2641","article-title":"CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile Virus Encephalitis","volume":"180","author":"Zhang","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2010.05.003_bib84","article-title":"CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy","author":"Zhu","year":"2009","journal-title":"FASEB J."}],"container-title":["Journal of Neuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572810001876?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572810001876?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:14:36Z","timestamp":1759047276000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165572810001876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":84,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0165572810001876"],"URL":"https:\/\/doi.org\/10.1016\/j.jneuroim.2010.05.003","relation":{},"ISSN":["0165-5728"],"issn-type":[{"value":"0165-5728","type":"print"}],"subject":[],"published":{"date-parts":[[2010,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TNF-\u03b1-dependent regulation of CXCR3 expression modulates neuronal survival during West Nile virus encephalitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroimmunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneuroim.2010.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}