{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:08:14Z","timestamp":1773320894236,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jni-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimmunology"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.jneuroim.2014.11.005","type":"journal-article","created":{"date-parts":[[2014,11,16]],"date-time":"2014-11-16T20:30:30Z","timestamp":1416169830000},"page":"190-193","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Brain-derived neurotrophic factor expression increases after enzyme replacement therapy in Gaucher disease"],"prefix":"10.1016","volume":"278","author":[{"given":"Filippo","family":"Vairo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Sperb-Ludwig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matheus","family":"Wilke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristiane","family":"Michellin-Tirelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Netto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eurico Camargo","family":"Neto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida Vanessa","family":"Doederlein Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jneuroim.2014.11.005_bb0005","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.conb.2007.03.013","article-title":"Neurotrophins, synaptic plasticity and dementia","volume":"17","author":"Arancio","year":"2007","journal-title":"Curr. Opin. Neurobiol."},{"issue":"1","key":"10.1016\/j.jneuroim.2014.11.005_bb0010","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.pharmthera.2012.01.006","article-title":"Brain derived neurotrophic factor: a novel neurotrophin involved in psychiatric and neurological disorders","volume":"134","author":"Balaratnasingam","year":"2012","journal-title":"Pharmacol. Ther."},{"issue":"451","key":"10.1016\/j.jneuroim.2014.11.005_bb0015","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1651-2227.2006.tb02398.x","article-title":"Gaucher disease: multiple lessons from a single gene disorder","volume":"95","author":"Beutler","year":"2006","journal-title":"Acta Paediatr. Suppl."},{"issue":"3","key":"10.1016\/j.jneuroim.2014.11.005_bb0020","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/08977190410001723308","article-title":"Brain-derived neurotrophic factor","volume":"22","author":"Binder","year":"2004","journal-title":"Growth Factors"},{"issue":"6","key":"10.1016\/j.jneuroim.2014.11.005_bb0025","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3109\/15622971003611319","article-title":"Serum and plasma BDNF levels in major depression: a replication study and meta-analyses","volume":"11","author":"Bocchio-Chiavetto","year":"2010","journal-title":"World J. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.jneuroim.2014.11.005_bb0030","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/dneu.20758","article-title":"The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity","volume":"70","author":"Castren","year":"2010","journal-title":"Dev. Neurobiol."},{"issue":"4","key":"10.1016\/j.jneuroim.2014.11.005_bb0035","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s10545-010-9095-5","article-title":"The neurological manifestations of Gaucher disease type 1: the French Observatoire on Gaucher disease (FROG)","volume":"33","author":"Cherin","year":"2010","journal-title":"J. Inherit. Metab. Dis."},{"issue":"4","key":"10.1016\/j.jneuroim.2014.11.005_bb0040","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1093\/hmg\/ddt468","article-title":"Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration","volume":"23","author":"Farfel-Becker","year":"2014","journal-title":"Hum. Mol. Genet."},{"issue":"12","key":"10.1016\/j.jneuroim.2014.11.005_bb0045","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1136\/jmg.2004.024455","article-title":"Parkinsonism among Gaucher disease carriers","volume":"41","author":"Goker-Alpan","year":"2004","journal-title":"J. Med. Genet."},{"issue":"3","key":"10.1016\/j.jneuroim.2014.11.005_bb0050","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1177\/0891988708316860","article-title":"Serum brain-derived neurotrophic factor is associated with cognitive function in healthy older adults","volume":"21","author":"Gunstad","year":"2008","journal-title":"J. Geriatr. Psychiatry Neurol."},{"issue":"6","key":"10.1016\/j.jneuroim.2014.11.005_bb0055","first-page":"521","article-title":"The impact of Gaucher disease and its treatment on quality of life","volume":"7","author":"Hayes","year":"1998","journal-title":"Qual. Life Res. Int. J. Qual. Life Asp. Treat. Care Rehab."},{"issue":"23-24","key":"10.1016\/j.jneuroim.2014.11.005_bb0060","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1007\/s10354-010-0864-4","article-title":"The pathophysiology of GD \u2014 current understanding and rationale for existing and emerging therapeutic approaches","volume":"160","author":"Hughes","year":"2010","journal-title":"Wien. Med. Wochenschr."},{"issue":"2","key":"10.1016\/j.jneuroim.2014.11.005_bb0065","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00401-004-0919-y","article-title":"Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains","volume":"109","author":"Imamura","year":"2005","journal-title":"Acta Neuropathol."},{"issue":"2","key":"10.1016\/j.jneuroim.2014.11.005_bb0070","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1365-2141.2004.05351.x","article-title":"Gaucher disease: pathological mechanisms and modern management","volume":"129","author":"Jmoudiak","year":"2005","journal-title":"Br. J. Haematol."},{"issue":"4","key":"10.1016\/j.jneuroim.2014.11.005_bb0075","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/emm.2006.41","article-title":"Downregulation of neurotrophic factors in the brain of a mouse model of Gaucher disease; implications for neuronal loss in Gaucher disease","volume":"38","author":"Kim","year":"2006","journal-title":"Exp. Mol. Med."},{"issue":"5","key":"10.1016\/j.jneuroim.2014.11.005_bb0080","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.biopsych.2007.01.002","article-title":"Correlation between serum brain-derived neurotrophic factor level and an in vivo marker of cortical integrity","volume":"62","author":"Lang","year":"2007","journal-title":"Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.jneuroim.2014.11.005_bb0085","doi-asserted-by":"crossref","first-page":"231","DOI":"10.4306\/pi.2010.7.4.231","article-title":"The roles of BDNF in the pathophysiology of major depression and in antidepressant treatment","volume":"7","author":"Lee","year":"2010","journal-title":"Psychiatry Investig."},{"issue":"3","key":"10.1016\/j.jneuroim.2014.11.005_bb0090","first-page":"263","article-title":"Quality of life assessment in adults with type 1 Gaucher disease","volume":"8","author":"Masek","year":"1999","journal-title":"Qual. Life Res. Int. J. Qual. Life Asp. Treat. Care Rehab."},{"issue":"Suppl. 1","key":"10.1016\/j.jneuroim.2014.11.005_bb0095","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1007\/s00431-003-1348-y","article-title":"Lysosomal storage disorders: emerging therapeutic options require early diagnosis","volume":"162","author":"Meikle","year":"2003","journal-title":"Eur. J. Pediatr."},{"issue":"1","key":"10.1016\/j.jneuroim.2014.11.005_bb0100","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/ajh.21888","article-title":"A reappraisal of Gaucher disease-diagnosis and disease management algorithms","volume":"86","author":"Mistry","year":"2011","journal-title":"Am. J. Hematol."},{"issue":"1","key":"10.1016\/j.jneuroim.2014.11.005_bb0105","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0301-0082(00)00014-9","article-title":"Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease","volume":"63","author":"Murer","year":"2001","journal-title":"Prog. Neurobiol."},{"issue":"6","key":"10.1016\/j.jneuroim.2014.11.005_bb0110","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1001\/jamaneurol.2013.1925","article-title":"A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies","volume":"70","author":"Nalls","year":"2013","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.jneuroim.2014.11.005_bb0115","first-page":"31","article-title":"Quality of life of Brazilian patients with Gaucher disease and Fabry disease","volume":"7","author":"Oliveira","year":"2013","journal-title":"JIMD Rep."},{"issue":"4","key":"10.1016\/j.jneuroim.2014.11.005_bb0120","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1007\/s00415-009-5357-2","article-title":"Serum levels of brain-derived neurotrophic factor correlate with motor impairment in Parkinson's disease","volume":"257","author":"Scalzo","year":"2010","journal-title":"J. Neurol."},{"issue":"17","key":"10.1016\/j.jneuroim.2014.11.005_bb0125","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1212\/WNL.0b013e3181b28601","article-title":"Mutations in GBA are associated with familial Parkinson disease susceptibility and age at onset","volume":"73","author":"Sidransky","year":"2009","journal-title":"Neurology"},{"issue":"19","key":"10.1016\/j.jneuroim.2014.11.005_bb0130","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1212\/WNL.0b013e3182735e9a","article-title":"GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology","volume":"79","author":"Tsuang","year":"2012","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.jneuroim.2014.11.005_bb0135","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ymgme.2007.03.004","article-title":"Glucocerebrosidase mutations in Chinese subjects from Taiwan with sporadic Parkinson disease","volume":"91","author":"Ziegler","year":"2007","journal-title":"Mol. Genet. Metab."}],"container-title":["Journal of Neuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572814009515?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572814009515?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:25:42Z","timestamp":1759047942000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165572814009515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":27,"alternative-id":["S0165572814009515"],"URL":"https:\/\/doi.org\/10.1016\/j.jneuroim.2014.11.005","relation":{},"ISSN":["0165-5728"],"issn-type":[{"value":"0165-5728","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brain-derived neurotrophic factor expression increases after enzyme replacement therapy in Gaucher disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroimmunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneuroim.2014.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}