{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:38:46Z","timestamp":1791247126923,"version":"4.1.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jni-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimmunology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.jneuroim.2015.11.005","type":"journal-article","created":{"date-parts":[[2015,11,10]],"date-time":"2015-11-10T05:37:30Z","timestamp":1447133850000},"page":"168-176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Guillain Barr\u00e9 syndrome (GBS): new insights in the molecular mimicry between C. jejuni and human peripheral nerve (HPN) proteins"],"prefix":"10.1016","volume":"289","author":[{"given":"Aida","family":"Loshaj-Shala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Regazzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armond","family":"Daci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marica","family":"Orioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina","family":"Brezovska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Poceva","family":"Panovska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giangiacomo","family":"Beretta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ljubica","family":"Suturkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneuroim.2015.11.005_bb0005","doi-asserted-by":"crossref","first-page":"4993","DOI":"10.1128\/AEM.01390-13","article-title":"Proteome of the nematode-trapping cells of the fungus monacrosporium haptotylum","volume":"79","author":"Andersson","year":"2013","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0010","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0165-5728(99)00279-9","article-title":"Campylobacter jejuni lipopolysaccharides from Guillain\u2013Barr\u00e9 syndrome patients induce IgG anti-GM1 antibodiesin rabbits","volume":"104","author":"Ang","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0015","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1379\/1466-1268(2002)007<0330:LIDTCA>2.0.CO;2","article-title":"Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70","volume":"7","author":"Arispe","year":"2002","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0020","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M200497200","article-title":"Novel signal transduction pathway utilized by extracellular HSP70","author":"Asea","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0025","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1128\/iai.62.5.2122-2125.1994","article-title":"Lipopolysaccharides from Campylobacter jejuni associated with Guillain\u2013Barre syndrome patients mimic human gangliosides in structure","volume":"62","author":"Aspinall","year":"1994","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0030","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.lwt.2014.01.011","article-title":"Effect of lyoprotectants on \u03b2-glucosidase activity and viability of Bifidobacterium infantis after freeze-drying and storage in milk and low pH juices","volume":"57","author":"Basholli-Salihu","year":"2014","journal-title":"LWT Food Sci. Technol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0035","first-page":"96","article-title":"Serum levels of free heat shock protein 70 and anti-HSP70 are elevated in Beh\u00e7et's disease","volume":"26","author":"Birtas-Atesoglu","year":"2008","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0040","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye-binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0045","doi-asserted-by":"crossref","first-page":"125","DOI":"10.4103\/0976-3147.83576","article-title":"Immunoreactivity of glycoproteins isolated from human peripheral nerve and Campylobacter jejuni (O:19)","volume":"2","author":"Brezovska","year":"2011","journal-title":"J. Neurosci. Rural Pract."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0050","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1136\/jnnp.73.1.76","article-title":"An antibody to VacA of Helicobacter pylori in cerebrospinal fluid from patients with Guillain\u2013Barre syndrome","volume":"73","author":"Chiba","year":"2002","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0055","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1128\/mr.57.2.402-414.1993","article-title":"Heat shock proteins: molecular chaperones of protein biogenesis","volume":"57","author":"Craig","year":"1993","journal-title":"Microbiol. Rev."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0060","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s12192-013-0484-1","article-title":"T cell recognition of naturally presented epitopes of self-heat shock protein 70","volume":"19","author":"De Jong","year":"2014","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0065","doi-asserted-by":"crossref","first-page":"307","DOI":"10.5114\/ceji.2012.32716","article-title":"Experimental immunology human Hsp60 could be a possible target of immune response triggered by Hsp60 of salmonella enteritidis \u2014 a preliminary study","volume":"4","author":"Dera-Tomaszewska","year":"2012","journal-title":"Cent. Eur. J. Immunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0081155","article-title":"Epitopes of microbial and human heat shock protein 60 and their recognition in myalgic encephalomyelitis","volume":"8","author":"Elfaitouri","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0081155","article-title":"Epitopes of microbial and human heat shock protein 60 and their recognition in myalgic encephalomyelitis","volume":"8","author":"Elfaitouri","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0080","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0165-5728(99)00269-6","article-title":"Anti-PMP22 antibodies in patients with inflammatory neuropathy","volume":"104","author":"Gabriel","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0085","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/ana.410390105","article-title":"Pathology of the motor-sensory axonal Guillain\u2013Barr\u00e9 syndrome","volume":"39","author":"Griffin","year":"1996","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0090","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1379\/1466-1268(2000)005<0438:HPMEOP>2.0.CO;2","article-title":"Hsp70 plasma membrane expression on primary tumor biopsy material and bone marrow of leukemic patients","volume":"5","author":"Hantschel","year":"2000","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0095","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jneuroim.2010.04.024","article-title":"Anti-heat shock protein 70 antibody levels are increased in myasthenia gravis and Guillain\u2013Barr\u00e9 syndrome","volume":"225","author":"Helgeland","year":"2010","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0100","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0165-5728(99)00195-2","article-title":"Pathogenesis of Guillain\u2013Barr\u00e9 syndrome","volume":"100","author":"Hughes","year":"1999","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0105","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1093\/brain\/awm004","article-title":"Immunotherapy for Guillain\u2013Barr\u00e9 syndrome: a systematic review","volume":"130","author":"Hughes","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0110","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0140-6736(05)66827-4","article-title":"Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis","volume":"366","author":"Kamphuis","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0115","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.aca.2008.04.043","article-title":"Interferences and contaminants encountered in modern mass spectrometry","volume":"627","author":"Keller","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0120","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0165-5728(93)90255-W","article-title":"Antibody responses to P0 and P2 myelin proteins in Guillain\u2013Barr\u00e9 syndrome and chronic idiopathicdemyelinating polyradiculoneuropathy","volume":"46","author":"Khalili-Shirazi","year":"1993","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0125","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/mus.20076","article-title":"Advances in understanding and treatment of immune-mediated disorders of the peripheral nervous system","volume":"30","author":"Kieseier","year":"2004","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0130","doi-asserted-by":"crossref","first-page":"A1","DOI":"10.1136\/ard.2010.148981.6","article-title":"CD4+ T cell responses to epitopes of self - heat shock protein 70 in patients with juvenile dermatomyositis","volume":"70","author":"Koffeman","year":"2011","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0135","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/ana.410330304","article-title":"Campylobacter jejuni strains from patients with Guillain\u2013Barr\u00e9 syndrome belong mostly to penner serogroup 19 and contain beta-N-acetylglucosamine residues","volume":"33","author":"Kuroki","year":"1993","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0140","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0145","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jneuroim.2007.01.022","article-title":"Proteome analysis of cerebrospinal fluid in Guillain\u2013Barr\u00e9 syndrome (GBS)","volume":"185","author":"Lehmensiek","year":"2007","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0150","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0155","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1136\/jnnp-2011-300174","article-title":"Epstein-barr virus and multiple sclerosis","volume":"82","author":"Lucas","year":"2011","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0160","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.2119\/molmed.2012.00119","article-title":"Heat shock protein 70: roles in multiple sclerosis","volume":"18","author":"Mansilla","year":"2012","journal-title":"Mol. Med."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0165","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jpba.2014.11.050","article-title":"Protein profile of exhaled breath condensate determined by high resolution mass spectrometry","volume":"105","author":"Muccilli","year":"2015","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0170","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jneumeth.2006.07.003","article-title":"Two-dimensional gel electrophoresis of peripheral nerve proteins: optimized sample preparation","volume":"159","author":"Qualtieri","year":"2007","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0175","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ana.410270713","article-title":"Antibodies to gangliosides and myelin proteins in Guillain\u2013Barr\u00e9 syndrome","volume":"27","author":"Quarles","year":"1990","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0180","first-page":"48","article-title":"Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid graves' disease","volume":"70","author":"Ratanachaiyavong","year":"1991","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0185","article-title":"Antibodies to glycoproteins shared by human peripheral nerve and Campylobacter jejuni in patients with multifocal motor neuropathy","volume":"2013","author":"Suturkova","year":"2013","journal-title":"Autoimmune Dis."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0190","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1042\/BST0320636","article-title":"Heat-shock protein 70 and heat-shock protein 90 associate with toll-like receptor 4 in response to bacterial lipopolysaccharide","volume":"32","author":"Triantafilou","year":"2004","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2011\/618127","article-title":"Hsp70 and its molecular role in nervous system diseases","volume":"2011","author":"Turturici","year":"2011","journal-title":"Biochem. Res. Int."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0200","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.bbrc.2006.05.070","article-title":"In vivo proteomic analysis of the intracellular bacterial pathogen, Francisella tularensis, isolated from mouse spleen","volume":"345","author":"Twine","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0205","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.bbrc.2014.11.059","article-title":"Proteomics-based identification of immunodominant proteins of Brucellae using sera from infected hosts points towards enhanced pathogen survival during the infection","volume":"456","author":"Wareth","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0210","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1093\/brain\/awf272","article-title":"Peripheral neuropathies and anti-glycolipid antibodies","volume":"125","author":"Willison","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0215","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0165-5728(97)00095-7","article-title":"Induction of anti-GM1 ganglioside antibodies by Campylobacter jejuni lipopolysaccharides","volume":"78","author":"Wirguin","year":"1997","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0220","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s10571-007-9257-7","article-title":"Comparative proteomics analysis of cerebrospinal fluid of patients with Guillain\u2013Barr\u00e9 syndrome","volume":"28","author":"Yang","year":"2008","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0225","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jneuroim.2004.07.017","article-title":"Prevalence of anti-heat shock protein antibodies in cerebrospinal fluids of patients with Guillain\u2013Barr\u00e9 syndrome","volume":"156","author":"Yonekura","year":"2004","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0230","doi-asserted-by":"crossref","first-page":"299","DOI":"10.2183\/pjab.88.299","article-title":"Guillain-Barr\u00e9 syndrome and anti-ganglioside antibodies: a clinician-scientist's journey","volume":"88","author":"Yuki","year":"2012","journal-title":"Proc. Jpn. Acad. Ser. B Phys. Biol. Sci."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0235","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1084\/jem.178.5.1771","article-title":"A bacterium lipopolysaccharide that elicits Guillain\u2013Barr\u00e9 syndrome has a GM1 ganglioside-like structure","volume":"178","author":"Yuki","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0240","doi-asserted-by":"crossref","first-page":"11404","DOI":"10.1073\/pnas.0402391101","article-title":"Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain\u2013Barre syndrome","volume":"101","author":"Yuki","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jneuroim.2015.11.005_bb0245","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.neuroscience.2008.12.034","article-title":"Toll-like receptor-2, CD14 and heat-shock protein 70 in inflammatory lesions of rat experimental autoimmune neuritis","volume":"159","author":"Zhang","year":"2009","journal-title":"Neuroscience"}],"container-title":["Journal of Neuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572815300722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572815300722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:27:27Z","timestamp":1759048047000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165572815300722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":49,"alternative-id":["S0165572815300722"],"URL":"https:\/\/doi.org\/10.1016\/j.jneuroim.2015.11.005","relation":{},"ISSN":["0165-5728"],"issn-type":[{"value":"0165-5728","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Guillain Barr\u00e9 syndrome (GBS): new insights in the molecular mimicry between C. jejuni and human peripheral nerve (HPN) proteins","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroimmunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneuroim.2015.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}