{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T17:51:20Z","timestamp":1785520280585,"version":"3.56.0"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jni-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimmunology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.jneuroim.2017.12.018","type":"journal-article","created":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T19:54:44Z","timestamp":1514404484000},"page":"80-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["The neonatal anti-viral response fails to control measles virus spread in neurons despite interferon-gamma expression and a Th1-like cytokine profile"],"prefix":"10.1016","volume":"316","author":[{"given":"Priya","family":"Ganesan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manisha N.","family":"Chandwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick S.","family":"Creisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa","family":"Bohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren A.","family":"O'Donnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneuroim.2017.12.018_bb0005","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/nri1394","article-title":"Neonatal adaptive immunity comes of age","volume":"4","author":"Adkins","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0010","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.cell.2006.02.015","article-title":"Pathogen recognition and innate immunity","volume":"124","author":"Akira","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0015","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.imlet.2004.07.006","article-title":"Dengue-specific CD8+ T cells have both protective and pathogenic roles in dengue virus infection","volume":"95","author":"An","year":"2004","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0020","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1586\/1744666X.2014.942288","article-title":"Immune responses in neonates","volume":"10","author":"Basha","year":"2014","journal-title":"Expert. Rev. Clin. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0025","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev.immunol.17.1.189","article-title":"Natural killer cells in antiviral defense: function and regulation by innate cytokines","volume":"17","author":"Biron","year":"1999","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0030","doi-asserted-by":"crossref","first-page":"6048","DOI":"10.4049\/jimmunol.154.11.6048","article-title":"Expression and biologic characterization of the murine chemokine KC","volume":"154","author":"Bozic","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0035","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0022-1759(01)00446-X","article-title":"Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-gamma production and IFN-gamma-secreting cells","volume":"257","author":"Brice","year":"2001","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0040","doi-asserted-by":"crossref","first-page":"5628","DOI":"10.1128\/JVI.01152-06","article-title":"Synergistic roles of antibody and interferon in noncytolytic clearance of Sindbis virus from different regions of the central nervous system","volume":"81","author":"Burdeinick-Kerr","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0045","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1038\/nm0896-906","article-title":"Large clonal expansions of CD8+ T cells in acute infectious mononucleosis","volume":"2","author":"Callan","year":"1996","journal-title":"Nat. Med."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0050","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jneuroim.2014.12.012","article-title":"Homeostatic interferon expression in neurons is sufficient for early control of viral infection","volume":"279","author":"Cavanaugh","year":"2015","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0055","first-page":"57","article-title":"Interferon-gamma-induced inhibition of neuronal vesicular stomatitis virus infection is STAT1 dependent","volume":"10","author":"Chesler","year":"2004","journal-title":"J. Neuro-Oncol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0060","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.4049\/jimmunol.180.9.5771","article-title":"IL-10: the master regulator of immunity to infection","volume":"180","author":"Couper","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0065","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.neuint.2011.02.020","article-title":"Viral infection and neural stem\/progenitor cell's fate: implications in brain development and neurological disorders","volume":"59","author":"Das","year":"2011","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.virusres.2012.11.002","article-title":"Neutrophil in viral infections, friend or foe?","volume":"171","author":"Drescher","year":"2013","journal-title":"Virus Res."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0075","doi-asserted-by":"crossref","first-page":"e40499","DOI":"10.1371\/journal.pone.0040499","article-title":"Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection","volume":"7","author":"Empey","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s12974-016-0571-1","article-title":"Interferon gamma protects neonatal neural stem\/progenitor cells during measles virus infection of the brain","volume":"13","author":"Fantetti","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0085","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1126\/science.271.5256.1728","article-title":"Induction of TH1 and TH2 immunity in neonatal mice","volume":"271","author":"Forsthuber","year":"1996","journal-title":"Science"},{"issue":"249","key":"10.1016\/j.jneuroim.2017.12.018_bb0090","article-title":"Microglia versus myeloid cell nomenclature during brain inflammation","volume":"6","author":"Greter","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0095","doi-asserted-by":"crossref","first-page":"13509","DOI":"10.1128\/JVI.79.21.13509-13518.2005","article-title":"CD8 T cells require gamma interferon to clear borna disease virus from the brain and prevent immune system-mediated neuronal damage","volume":"79","author":"Hausmann","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0100","doi-asserted-by":"crossref","first-page":"e71643","DOI":"10.1371\/journal.pone.0071643","article-title":"TNF-alpha acts as an immunoregulator in the mouse brain by reducing the incidence of severe disease following Japanese encephalitis virus infection","volume":"8","author":"Hayasaka","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0105","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.bbadis.2008.08.001","article-title":"Viral parkinsonism","volume":"1792","author":"Jang","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0110","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1017\/S0033291712000736","article-title":"Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies","volume":"43","author":"Khandaker","year":"2013","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0115","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1128\/JVI.02710-12","article-title":"hsp70 and a novel axis of type I interferon-dependent antiviral immunity in the measles virus-infected brain","volume":"87","author":"Kim","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0120","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/sj.icb.7100012","article-title":"Immunopathology of flavivirus infections","volume":"85","author":"King","year":"2007","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0125","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0165-5728(96)00083-5","article-title":"Interferon-gamma induced type I nitric oxide synthase activity inhibits viral replication in neurons","volume":"68","author":"Komatsu","year":"1996","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0130","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1038\/pr.2014.135","article-title":"Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV","volume":"76","author":"Kopp","year":"2014","journal-title":"Pediatr. Res."},{"issue":"466","key":"10.1016\/j.jneuroim.2017.12.018_bb0135","article-title":"Immunity to RSV in early-life","volume":"5","author":"Lambert","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0140","doi-asserted-by":"crossref","first-page":"e51068","DOI":"10.1371\/journal.pone.0051068","article-title":"Effects of two commonly found strains of influenza A virus on developing dopaminergic neurons, in relation to the pathophysiology of schizophrenia","volume":"7","author":"Landreau","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0145","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1002\/eji.201243152","article-title":"Cytolytic effector pathways and IFN-gamma help protect against Japanese encephalitis","volume":"43","author":"Larena","year":"2013","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0150","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1128\/JVI.73.3.1795-1801.1999","article-title":"Immune response-mediated protection of adult but not neonatal mice from neuron-restricted measles virus infection and central nervous system disease","volume":"73","author":"Lawrence","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0155","doi-asserted-by":"crossref","first-page":"e76412","DOI":"10.1371\/journal.pone.0076412","article-title":"Mice deficient in interferon-gamma or interferon-gamma receptor 1 have distinct inflammatory responses to acute viral encephalomyelitis","volume":"8","author":"Lee","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0160","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S1074-7613(04)00072-X","article-title":"IL-4 utilizes an alternative receptor to drive apoptosis of Th1 cells and skews neonatal immunity toward Th2","volume":"20","author":"Li","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0165","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1128\/JVI.76.7.3202-3211.2002","article-title":"Lack of both Fas ligand and perforin protects from flavivirus-mediated encephalitis in mice","volume":"76","author":"Licon Luna","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0170","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0165-5728(99)00036-3","article-title":"Characterization of the inflammatory response during acute measles encephalitis in NSE-CD46 transgenic mice","volume":"96","author":"Manchester","year":"1999","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0175","doi-asserted-by":"crossref","first-page":"948","DOI":"10.4049\/jimmunol.1302007","article-title":"Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children","volume":"192","author":"Marr","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0180","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1128\/JVI.02077-14","article-title":"Proinflammatory effects of interferon gamma in mouse adenovirus 1 myocarditis","volume":"89","author":"McCarthy","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0185","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1096\/fj.07-099499","article-title":"Interferon-gamma directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-gamma receptor and AMPA GluR1 receptor","volume":"22","author":"Mizuno","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0190","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1146\/annurev.immunol.19.1.683","article-title":"Interleukin-10 and the interleukin-10 receptor","volume":"19","author":"Moore","year":"2001","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0195","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/S1567-5769(03)00131-0","article-title":"Anti-inflammatory properties of pro-inflammatory interferon-gamma","volume":"3","author":"Muhl","year":"2003","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0200","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/sj.gene.6363819","article-title":"Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL\/6 and DBA\/2","volume":"3","author":"Myrick","year":"2002","journal-title":"Genes Immun."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0205","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.4049\/jimmunol.1101356","article-title":"STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice","volume":"188","author":"O'Donnell","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0210","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/jnc.13250","article-title":"Interferon gamma induces protective non-canonical signaling pathways in primary neurons","volume":"135","author":"O'Donnell","year":"2015","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0215","doi-asserted-by":"crossref","first-page":"539","DOI":"10.3389\/fimmu.2015.00539","article-title":"Opposing roles of interferon-gamma on cells of the central nervous system in autoimmune neuroinflammation","volume":"6","author":"Ottum","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0220","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.cytogfr.2014.11.003","article-title":"NK cells and interferons","volume":"26","author":"Paolini","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0225","doi-asserted-by":"crossref","first-page":"4497","DOI":"10.1128\/JVI.76.9.4497-4506.2002","article-title":"Immune-mediated protection from measles virus-induced central nervous system disease is noncytolytic and gamma interferon dependent","volume":"76","author":"Patterson","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0230","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1128\/JVI.06797-11","article-title":"CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis","volume":"86","author":"Phares","year":"2012","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0235","doi-asserted-by":"crossref","first-page":"8842","DOI":"10.1128\/JVI.76.17.8842-8854.2002","article-title":"Enhanced cytomegalovirus infection of developing brain independent of the adaptive immune system","volume":"76","author":"van den Pol","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0240","doi-asserted-by":"crossref","first-page":"e1002670","DOI":"10.1371\/journal.ppat.1002670","article-title":"Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility","volume":"8","author":"Pott","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0245","doi-asserted-by":"crossref","first-page":"4659","DOI":"10.1073\/pnas.94.9.4659","article-title":"A transgenic mouse model for measles virus infection of the brain","volume":"94","author":"Rall","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0250","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/nri1708","article-title":"Regulation of MHC class II gene expression by the class II transactivator","volume":"5","author":"Reith","year":"2005","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0255","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/sj.gene.6364246","article-title":"Transcriptional response of human microglial cells to interferon-gamma","volume":"6","author":"Rock","year":"2005","journal-title":"Genes Immun."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0260","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nri2802","article-title":"Immunity and immunopathology to viruses: what decides the outcome?","volume":"10","author":"Rouse","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0265","doi-asserted-by":"crossref","first-page":"9888","DOI":"10.1128\/JVI.00956-12","article-title":"Interferon response factors 3 and 7 protect against chikungunya virus hemorrhagic fever and shock","volume":"86","author":"Rudd","year":"2012","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0270","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1099\/vir.0.82359-0","article-title":"Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease","volume":"88","author":"Ryman","year":"2007","journal-title":"J Gen Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0275","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1006\/bbrc.2001.5388","article-title":"Iba1 is an actin-cross-linking protein in macrophages\/microglia","volume":"286","author":"Sasaki","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0280","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1146\/annurev-immunol-032713-120231","article-title":"Interferon-stimulated genes: a complex web of host defenses","volume":"32","author":"Schneider","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0285","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0065-2776(07)96002-2","article-title":"Regulation of interferon-gamma during innate and adaptive immune responses","volume":"96","author":"Schoenborn","year":"2007","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0290","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1084\/jem.183.4.1613","article-title":"Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity","volume":"183","author":"Singh","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0295","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1189\/jlb.1212617","article-title":"TLR3 impairment in human newborns","volume":"94","author":"Slavica","year":"2013","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0300","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.virol.2016.09.013","article-title":"CD4+ T cells require either B cells or CD8+ T cells to control spread and pathogenesis of a neurotropic infection","volume":"499","author":"Solomos","year":"2016","journal-title":"Virology"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0305","doi-asserted-by":"crossref","first-page":"834","DOI":"10.3390\/v5030834","article-title":"Antiviral type I and type III interferon responses in the central nervous system","volume":"5","author":"Sorgeloos","year":"2013","journal-title":"Viruses."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0310","doi-asserted-by":"crossref","first-page":"e1005378","DOI":"10.1371\/journal.ppat.1005378","article-title":"Functional interplay between type I and II interferons is essential to limit influenza a virus-induced tissue inflammation","volume":"12","author":"Stifter","year":"2016","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0315","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.chom.2009.09.011","article-title":"Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection","volume":"6","author":"Stout-Delgado","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0320","doi-asserted-by":"crossref","first-page":"854","DOI":"10.4049\/jimmunol.144.3.854","article-title":"Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells","volume":"144","author":"Powell","year":"1990","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0325","doi-asserted-by":"crossref","first-page":"3664","DOI":"10.1128\/JVI.01496-10","article-title":"T cell-, interleukin-12-, and gamma interferon-driven viral clearance in measles virus-infected brain tissue","volume":"85","author":"Stubblefield Park","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0330","doi-asserted-by":"crossref","first-page":"10711","DOI":"10.1073\/pnas.1307868110","article-title":"TLR-independent neutrophil-derived IFN-gamma is important for host resistance to intracellular pathogens","volume":"110","author":"Sturge","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0335","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bbrc.2003.09.159","article-title":"Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains","volume":"311","author":"Tanabe","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0340","doi-asserted-by":"crossref","first-page":"11070","DOI":"10.1128\/JVI.01866-14","article-title":"Age-dependent myeloid dendritic cell responses mediate resistance to la crosse virus-induced neurological disease","volume":"88","author":"Taylor","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0345","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.virol.2006.01.050","article-title":"CD4 T cell control primary measles virus infection of the CNS: regulation is dependent on combined activity with either CD8 T cells or with B cells: CD4, CD8 or B cells alone are ineffective","volume":"347","author":"Tishon","year":"2006","journal-title":"Virology"},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0350","doi-asserted-by":"crossref","first-page":"6822","DOI":"10.1128\/JVI.00510-11","article-title":"Virally expressed interleukin-10 ameliorates acute encephalomyelitis and chronic demyelination in coronavirus-infected mice","volume":"85","author":"Trandem","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0355","doi-asserted-by":"crossref","first-page":"3642","DOI":"10.4049\/jimmunol.1003292","article-title":"Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis","volume":"186","author":"Trandem","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0360","doi-asserted-by":"crossref","first-page":"6013","DOI":"10.4049\/jimmunol.154.11.6013","article-title":"Recruitment and proliferation of CD8+ T cells in respiratory virus infections","volume":"154","author":"Tripp","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0365","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1128\/JVI.03089-12","article-title":"Transgenic CCL2 expression in the central nervous system results in a dysregulated immune response and enhanced lethality after coronavirus infection","volume":"87","author":"Trujillo","year":"2013","journal-title":"J. Virol."},{"issue":"5344","key":"10.1016\/j.jneuroim.2017.12.018_bb0370","article-title":"Protective role of TNF-alpha, IL-10 and IL-2 in mice infected with the Oshima strain of Tick-borne encephalitis virus","volume":"4","author":"Tun","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0375","doi-asserted-by":"crossref","first-page":"5278","DOI":"10.4049\/jimmunol.163.10.5278","article-title":"IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide","volume":"163","author":"Willenborg","year":"1999","journal-title":"J. Immunol."},{"issue":"7","key":"10.1016\/j.jneuroim.2017.12.018_bb0380","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/ni1087","article-title":"The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses","volume":"5","author":"Yoneyama","year":"2004","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0385","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.it.2009.09.002","article-title":"Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells","volume":"30","author":"Zaghouani","year":"2009","journal-title":"Trends Immunol."},{"key":"10.1016\/j.jneuroim.2017.12.018_bb0390","doi-asserted-by":"crossref","first-page":"12330","DOI":"10.1128\/JVI.01470-15","article-title":"MDA5 is critical to host defense during infection with murine coronavirus","volume":"89","author":"Zalinger","year":"2015","journal-title":"J. Virol."}],"container-title":["Journal of Neuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572817302722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572817302722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:31:53Z","timestamp":1759048313000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165572817302722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":78,"alternative-id":["S0165572817302722"],"URL":"https:\/\/doi.org\/10.1016\/j.jneuroim.2017.12.018","relation":{},"ISSN":["0165-5728"],"issn-type":[{"value":"0165-5728","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The neonatal anti-viral response fails to control measles virus spread in neurons despite interferon-gamma expression and a Th1-like cytokine profile","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroimmunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneuroim.2017.12.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}