{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:03:25Z","timestamp":1759104205317,"version":"3.44.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005945","name":"Hirosaki University Institutional Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005945","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jni-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimmunology"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.jneuroim.2019.577047","type":"journal-article","created":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T02:10:47Z","timestamp":1567476647000},"page":"577047","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC\/D3 human cerebral microvascular endothelial cells"],"prefix":"10.1016","volume":"337","author":[{"given":"Tadaatsu","family":"Imaizumi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urara","family":"Satake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruri","family":"Miyashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shogo","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoh","family":"Matsumiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Seya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangli","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jneuroim.2019.577047_bb0005","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/cen3.12416","article-title":"Expression of CCL5 is induced by polyinosinic-polycytidylic acid in cultured hCMEC\/D3 human brain microvascular endothelial cells","volume":"8","author":"Arai","year":"2017","journal-title":"Clin. Exp. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0010","doi-asserted-by":"crossref","first-page":"5976","DOI":"10.1007\/s12035-017-0816-8","article-title":"Toll-like receptor 3 mediates HIV-1-induced interleukin-6 expression in the human brain endothelium via TAK1 and JNK pathways: implications for viral neuropathogenesis","volume":"55","author":"Bhargavan","year":"2018","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0015","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.cell.2009.12.017","article-title":"The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus","volume":"139","author":"Brass","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.jneuroim.2019.577047_bb0020","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12974-019-1443-2","article-title":"The role of microglia in viral encephalitis","volume":"16","author":"Chen","year":"2019","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.jneuroim.2019.577047_bb0025","doi-asserted-by":"crossref","first-page":"23860","DOI":"10.1074\/jbc.270.40.23860","article-title":"Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth","volume":"270","author":"Deblandre","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0030","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/s12985-017-0875-5","article-title":"Investigation of antiviral state mediated by interferon-inducible transmembrane protein 1 induced by H9N2 virus and inactivated viral particle in human endothelial cells","volume":"14","author":"Feng","year":"2017","journal-title":"Virol. J."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0035","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s11908-017-0568-7","article-title":"Herpes simplex encephalitis: an update","volume":"19","author":"Gnann","year":"2017","journal-title":"Curr. Infect. Dis. Rep."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0040","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/joim.12570","article-title":"Alarmins and central nervous system inflammation in HIV-associated neurological disorders","volume":"281","author":"Gougeon","year":"2017","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0045","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.tim.2014.12.003","article-title":"Mx GTPases: dynamin-like antiviral machines of innate immunity","volume":"23","author":"Haller","year":"2015","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0050","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1073\/pnas.80.7.1910","article-title":"Interferon induces a unique protein in mouse cells bearing a gene for resistance to influenza virus","volume":"80","author":"Horisberger","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0055","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/cen3.12463","article-title":"Retinoic acid-inducible gene-I, melanoma differentiation-associated gene 5 and CXCL10 are induced by a TLR3 agonist in human brain microvascular endothelial cells","volume":"9","author":"Imaizumi","year":"2018","journal-title":"Clin. Exp. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0060","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jneuroim.2018.08.016","article-title":"Interferon-stimulated gene 60 (ISG60) constitutes a negative feedback loop in the downstream of TLR3 signaling in hCMEC\/D3 cells","volume":"324","author":"Imaizumi","year":"2018","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0065","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-28518-3","article-title":"The functional and inflammatory response of brain endothelial cells to Toll-like receptor agonists","volume":"8","author":"Johnson","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0070","first-page":"689","article-title":"Genes regulated by interferon-\u03b3 in human uterine microvascular endothelial cells","volume":"20","author":"Kitaya","year":"2007","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0075","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.neuron.2014.03.003","article-title":"Stepwise recruitment of transcellular and paracellular pathways underlies blood-brain barrier breakdown in stroke","volume":"82","author":"Knowland","year":"2014","journal-title":"Neuron."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0080","first-page":"374","article-title":"Interferon activation and innate immunity","volume":"2","author":"Le Page","year":"2000","journal-title":"Rev. Immunogenet."},{"key":"10.1016\/j.jneuroim.2019.577047_bb2000","doi-asserted-by":"crossref","first-page":"4248","DOI":"10.1074\/jbc.M114.630780","article-title":"A sorting signal supresses IFITM1 restriction of viral entry","volume":"290","author":"Li","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0085","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s11481-018-9821-6","article-title":"Mechanisms of blood-brain barrier disruption in herpes simplex encephalitis","volume":"14","author":"Liu","year":"2019","journal-title":"J. NeuroImmune Pharmacol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0090","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.coviro.2017.12.003","article-title":"New advances in CNS immunity against viral infection","volume":"28","author":"Manglani","year":"2018","journal-title":"Curr. Opin. Virol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0095","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.neuint.2010.07.002","article-title":"Expression and regulation of toll-like receptors in cerebral endothelial cells","volume":"57","author":"Nagyoszi","year":"2010","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0100","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jneuroim.2017.03.006","article-title":"Molecular mechanisms of neuroinflammation and injury during acute viral encephalitis","volume":"308","author":"Shives","year":"2017","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0105","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12879-017-2246-7","article-title":"Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era","volume":"17","author":"Solomon","year":"2017","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0110","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.molmed.2018.09.001","article-title":"Viral encephalitis and neurologic diseases: focus on astrocytes","volume":"24","author":"Soung","year":"2018","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0115","first-page":"2150","article-title":"Interferon-induced human protein with homology to protein mx of influenza virus-resistance mice","volume":"5","author":"Staeheli","year":"1985","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0120","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/09680519050110011101","article-title":"Evolution and integration of innate immune recognition systems: the Toll-like receptors","volume":"11","author":"Takeda","year":"2005","journal-title":"J. Endotoxin Res."},{"issue":"3","key":"10.1016\/j.jneuroim.2019.577047_bb0125","doi-asserted-by":"crossref","DOI":"10.1007\/s11910-015-0529-1","article-title":"Autoimmune encephalitis and its relation to infection","volume":"15","author":"Venkatesan","year":"2015","journal-title":"Curr Neurol Neurosci Rep."},{"key":"10.1016\/j.jneuroim.2019.577047_bb0130","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/2045-8118-10-16","article-title":"The hCMEC\/D3 cell line as a model of the human blood brain barrier","volume":"10","author":"Weksler","year":"2013","journal-title":"Fluids Barriers CNS"},{"key":"10.1016\/j.jneuroim.2019.577047_bb0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166382","article-title":"MxA is a novel regulator of endosome-associated transcriptional signaling by bone morphogenetic protein 4 and 9 (BMP4 and BMP9)","volume":"11","author":"Yuan","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jneuroim.2019.577047_bb0140","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.coi.2012.11.001","article-title":"TLR3 immunity to infection in mice and humans","volume":"25","author":"Zhang","year":"2013","journal-title":"Curr. Opin. Immunol."}],"container-title":["Journal of Neuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572819303030?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165572819303030?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:34:12Z","timestamp":1759048452000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165572819303030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":29,"alternative-id":["S0165572819303030"],"URL":"https:\/\/doi.org\/10.1016\/j.jneuroim.2019.577047","relation":{},"ISSN":["0165-5728"],"issn-type":[{"type":"print","value":"0165-5728"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC\/D3 human cerebral microvascular endothelial cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Neuroimmunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jneuroim.2019.577047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"577047"}}