{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T15:18:11Z","timestamp":1793978291834,"version":"4.8.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences","doi-asserted-by":"publisher","award":["2021-RC330-004"],"award-info":[{"award-number":["2021-RC330-004"]}],"id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences","doi-asserted-by":"publisher","award":["2022-ZHCH330-01"],"award-info":[{"award-number":["2022-ZHCH330-01"]}],"id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine","doi-asserted-by":"publisher","award":["2023-I2M-2-001"],"award-info":[{"award-number":["2023-I2M-2-001"]}],"id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine","doi-asserted-by":"publisher","award":["2023ZD0506001"],"award-info":[{"award-number":["2023ZD0506001"]}],"id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002799","name":"Capital Medical University","doi-asserted-by":"publisher","award":["PYZ24037"],"award-info":[{"award-number":["PYZ24037"]}],"id":[{"id":"10.13039\/501100002799","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011176","name":"Peking Union Medical College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011176","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of nutrition, health and aging"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jnha.2025.100670","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T14:41:14Z","timestamp":1757515274000},"page":"100670","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Association between long-term burden of sarcopenia and cardiorespiratory multimorbidity"],"prefix":"10.1016","volume":"29","author":[{"given":"Zuolin","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunyuan","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihao","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawen","family":"Ke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yachen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yabing","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruitai","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10258","key":"10.1016\/j.jnha.2025.100670_bib0005","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","article-title":"Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"396","author":"Diseases","year":"2020","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.jnha.2025.100670_bib0010","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.cjco.2025.01.001","article-title":"The intersection of chronic obstructive pulmonary disease and cardiovascular disease: recent insights in a challenging area","volume":"7","author":"Heffernan","year":"2025","journal-title":"CJC Open"},{"issue":"17","key":"10.1016\/j.jnha.2025.100670_bib0015","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1016\/j.jacc.2018.11.063","article-title":"Association of Cardiovascular Disease With Respiratory Disease","volume":"73","author":"Carter","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.jnha.2025.100670_bib0020","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.chest.2023.11.009","article-title":"Cardiorespiratory multimorbidity in people living with chronic lung disease: challenges, opportunities, and a concept for optimization via an integrated care approach","volume":"165","author":"Frost","year":"2024","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.jnha.2025.100670_bib0025","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1513\/pats.200404-032MS","article-title":"Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality","volume":"2","author":"Sin","year":"2005","journal-title":"Proc Am Thorac Soc"},{"issue":"149","key":"10.1016\/j.jnha.2025.100670_bib0030","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0057-2018","article-title":"Cardiovascular disease and COPD: dangerous liaisons?","volume":"27","author":"Rabe","year":"2018","journal-title":"Eur Respir Rev"},{"issue":"1","key":"10.1016\/j.jnha.2025.100670_bib0035","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"issue":"2","key":"10.1016\/j.jnha.2025.100670_bib0040","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s13539-010-0014-2","article-title":"An overview of sarcopenia: facts and numbers on prevalence and clinical impact","volume":"1","author":"von Haehling","year":"2010","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"20","key":"10.1016\/j.jnha.2025.100670_bib0045","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1161\/CIRCULATIONAHA.123.064071","article-title":"Sarcopenia and cardiovascular diseases","volume":"147","author":"Damluji","year":"2023","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jnha.2025.100670_bib0050","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1002\/jcsm.12600","article-title":"Diagnosis, prevalence, and clinical impact of sarcopenia in COPD: a systematic review and meta-analysis","volume":"11","author":"Sepulveda-Loyola","year":"2020","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"5","key":"10.1016\/j.jnha.2025.100670_bib0055","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1002\/jcsm.13541","article-title":"Bidirectional transitions of sarcopenia states in older adults: the longitudinal evidence from CHARLS","volume":"15","author":"Luo","year":"2024","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.jnha.2025.100670_bib0060","series-title":"Encyclopedia of geropsychology","first-page":"1","article-title":"China Health and Retirement Longitudinal Study (CHARLS)","author":"Chen","year":"2015"},{"issue":"1","key":"10.1016\/j.jnha.2025.100670_bib0065","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/ije\/dys203","article-title":"Cohort profile: the China Health and Retirement Longitudinal Study (CHARLS)","volume":"43","author":"Zhao","year":"2014","journal-title":"Int J Epidemiol"},{"issue":"3","key":"10.1016\/j.jnha.2025.100670_bib0070","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian Working Group for Sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J Am Med Dir Assoc"},{"issue":"4","key":"10.1016\/j.jnha.2025.100670_bib0075","first-page":"551","article-title":"Anthropometric equation for estimation of appendicular skeletal muscle mass in Chinese adults","volume":"20","author":"Wen","year":"2011","journal-title":"Asia Pac J Clin Nutr"},{"issue":"2","key":"10.1016\/j.jnha.2025.100670_bib0080","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/joim.13808","article-title":"Trend in prevalence, associated risk factors, and longitudinal outcomes of sarcopenia in China: a national cohort study","volume":"296","author":"Qiu","year":"2024","journal-title":"J Intern Med"},{"issue":"6","key":"10.1016\/j.jnha.2025.100670_bib0085","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1002\/jcsm.13081","article-title":"Sarcopenia and mild cognitive impairment among elderly adults: the first longitudinal evidence from CHARLS","volume":"13","author":"Hu","year":"2022","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"3","key":"10.1016\/j.jnha.2025.100670_bib0090","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1002\/jcsm.12997","article-title":"Sarcopenia and catastrophic health expenditure by socio-economic groups in China: an analysis of household-based panel data","volume":"13","author":"Ye","year":"2022","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.jnha.2025.100670_bib0095","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.psychres.2018.08.076","article-title":"Association between physical activity and depressive symptoms in general adult populations: an analysis of the dose-response relationship","volume":"269","author":"Kim","year":"2018","journal-title":"Psychiatry Res"},{"issue":"9","key":"10.1016\/j.jnha.2025.100670_bib0100","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.27573","article-title":"Prevalence of dyslipidemia and availability of lipid-lowering medications among primary health care settings in China","volume":"4","author":"Lu","year":"2021","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jnha.2025.100670_bib0105","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev.clinpsy.121208.131413","article-title":"Group-based trajectory modeling in clinical research","volume":"6","author":"Nagin","year":"2010","journal-title":"Annu Rev Clin Psychol"},{"issue":"4","key":"10.1016\/j.jnha.2025.100670_bib0110","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s12603-023-1906-1","article-title":"Association between sarcopenia and cognitive trajectories among middle-aged and older adults in China: a nationally representative cohort study","volume":"27","author":"Xue","year":"2023","journal-title":"J Nutr Health Aging"},{"issue":"10191","key":"10.1016\/j.jnha.2025.100670_bib0115","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1016\/S0140-6736(19)31138-9","article-title":"Sarcopenia","volume":"393","author":"Cruz-Jentoft","year":"2019","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.jnha.2025.100670_bib0120","doi-asserted-by":"crossref","DOI":"10.3390\/nu12010211","article-title":"Sarcopenia and heart failure","volume":"12","author":"Curcio","year":"2020","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.jnha.2025.100670_bib0125","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1002\/jcsm.13221","article-title":"Sarcopenia and cardiovascular diseases: a systematic review and meta-analysis","volume":"14","author":"Zuo","year":"2023","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"154","key":"10.1016\/j.jnha.2025.100670_bib0130","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0049-2019","article-title":"Sarcopenia in COPD: a systematic review and meta-analysis","volume":"28","author":"Benz","year":"2019","journal-title":"Eur Respir Rev"},{"issue":"1","key":"10.1016\/j.jnha.2025.100670_bib0135","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s40520-024-02855-y","article-title":"Exploring the relationship between sarcopenia and 11 respiratory diseases: a comprehensive Mendelian randomization analysis","volume":"36","author":"Su","year":"2024","journal-title":"Aging Clin Exp Res"},{"key":"10.1016\/j.jnha.2025.100670_bib0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2023.112257","article-title":"The association between sarcopenia and incident chronic lung disease in the general population: a longitudinal study based on CHARLS data","volume":"180","author":"Wang","year":"2023","journal-title":"Exp Gerontol"},{"issue":"20","key":"10.1016\/j.jnha.2025.100670_bib0145","doi-asserted-by":"crossref","DOI":"10.3390\/nu16203428","article-title":"Acute sarcopenia: mechanisms and management","volume":"16","author":"Damanti","year":"2024","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jnha.2025.100670_bib0150","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1164\/rccm.201203-0455PP","article-title":"The relationship between lung inflammation and cardiovascular disease","volume":"186","author":"Van Eeden","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.jnha.2025.100670_bib0155","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1186\/s12967-023-04361-7","article-title":"Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease","volume":"21","author":"Yan","year":"2023","journal-title":"J Transl Med"},{"issue":"23","key":"10.1016\/j.jnha.2025.100670_bib0160","doi-asserted-by":"crossref","first-page":"e472","DOI":"10.1161\/CIR.0000000000001031","article-title":"2021 dietary guidance to improve cardiovascular health: a scientific statement from the American Heart Association","volume":"144","author":"Lichtenstein","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jnha.2025.100670_bib0165","article-title":"Correlation between hs-CRP, IL-6, IL-10, ET-1, and chronic obstructive pulmonary disease combined with pulmonary hypertension","volume":"2022","author":"Yang","year":"2022","journal-title":"J Healthc Eng"},{"issue":"12","key":"10.1016\/j.jnha.2025.100670_bib0170","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1139\/cjpp-2024-0201","article-title":"Sarcopenia: recent advances for detection, progression, and metabolic alterations along with therapeutic targets","volume":"102","author":"Ali","year":"2024","journal-title":"Can J Physiol Pharmacol"},{"issue":"15","key":"10.1016\/j.jnha.2025.100670_bib0175","doi-asserted-by":"crossref","DOI":"10.3390\/cells11152359","article-title":"Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update","volume":"11","author":"Jimenez-Gutierrez","year":"2022","journal-title":"Cells"},{"issue":"3","key":"10.1016\/j.jnha.2025.100670_bib0180","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jamda.2012.10.009","article-title":"Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review","volume":"14","author":"Mijnarends","year":"2013","journal-title":"J Am Med Dir Assoc"},{"key":"10.1016\/j.jnha.2025.100670_bib0185","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2024.1509519","article-title":"Factors, mechanisms and improvement methods of muscle strength loss","volume":"12","author":"Wang","year":"2024","journal-title":"Front Cell Dev Biol"}],"container-title":["The Journal of nutrition, health and aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1279770725001952?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1279770725001952?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T11:34:34Z","timestamp":1772883274000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1279770725001952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":37,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S1279770725001952"],"URL":"https:\/\/doi.org\/10.1016\/j.jnha.2025.100670","relation":{},"ISSN":["1279-7707"],"issn-type":[{"value":"1279-7707","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between long-term burden of sarcopenia and cardiorespiratory multimorbidity","name":"articletitle","label":"Article Title"},{"value":"The Journal of nutrition, health and aging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnha.2025.100670","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Masson SAS on behalf of SERDI Publisher.","name":"copyright","label":"Copyright"}],"article-number":"100670"}}