{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T01:23:59Z","timestamp":1782437039514,"version":"3.54.5"},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the National Medical Association"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jnma.2025.08.099","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T19:44:45Z","timestamp":1757015085000},"page":"412-423","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Association between hemoglobin albumin lymphocyte and platelet (HALP) score and psoriasis: Evidence from NHANES"],"prefix":"10.1016","volume":"117","author":[{"given":"Min","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangfang","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuping","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enfa","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 2","key":"10.1016\/j.jnma.2025.08.099_bib0001","doi-asserted-by":"crossref","first-page":"ii30","DOI":"10.1136\/ard.2004.031120","article-title":"Psoriasis pathophysiology: current concepts of pathogenesis","volume":"64","author":"Krueger","year":"2005","journal-title":"Ann Rheum Dis"},{"issue":"11","key":"10.1016\/j.jnma.2025.08.099_bib0002","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines9111511","article-title":"Psoriasis as an immune-mediated and inflammatory systemic disease: from pathophysiology to novel therapeutic approaches","volume":"9","author":"Campanati","year":"2021","journal-title":"Biomedicines"},{"issue":"3","key":"10.1016\/j.jnma.2025.08.099_bib0003","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s13555-021-00518-8","article-title":"Psoriasis prevalence and severity by expert elicitation","volume":"11","author":"Papp","year":"2021","journal-title":"Dermatol Ther (Heidelb)"},{"issue":"1","key":"10.1016\/j.jnma.2025.08.099_bib0004","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1177\/247553031319a00102","volume":"19a","author":"Butler","year":"2013","journal-title":"Psoriasis: Impact Qual Life"},{"issue":"19","key":"10.1016\/j.jnma.2025.08.099_bib0005","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1001\/jama.2020.4006","article-title":"Clinical presentation, and treatment of psoriasis: a review","volume":"323","author":"Armstrong","year":"2020","journal-title":"Jama"},{"issue":"19","key":"10.1016\/j.jnma.2025.08.099_bib0006","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221910841","article-title":"Skin barrier dysregulation in psoriasis","volume":"22","author":"Orsmond","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"4","key":"10.1016\/j.jnma.2025.08.099_bib0007","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1007\/s10067-019-04456-x","article-title":"Efficacy of \u03c9-3 supplementation in patients with psoriasis: a meta-analysis of randomized controlled trials","volume":"38","author":"Clark","year":"2019","journal-title":"Clin Rheumatol"},{"issue":"2","key":"10.1016\/j.jnma.2025.08.099_bib0008","article-title":"The effect of antioxidant and anti-inflammatory capacity of diet on psoriasis and psoriatic arthritis phenotype: nutrition as therapeutic tool?","volume":"10","author":"Katsimbri","year":"2021","journal-title":"Antioxid (Basel Switz)"},{"issue":"8","key":"10.1016\/j.jnma.2025.08.099_bib0009","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202300720","article-title":"Bcat2-Mediated branched-chain amino acid catabolism is linked to the aggravated inflammation in Obese with psoriasis mice","volume":"68","author":"Wang","year":"2024","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.jnma.2025.08.099_bib0010","doi-asserted-by":"crossref","first-page":"66","DOI":"10.70470\/SHIFAA\/2023\/008","article-title":"Investigating the role of gut microbiota dysbiosis in the pathogenesis and advancement of Alzheimer's Disease: a comprehensive multi-omics approach","volume":"2023","author":"Abdulrahman","year":"2023","journal-title":"SHIFAA"},{"issue":"10","key":"10.1016\/j.jnma.2025.08.099_bib0011","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.4049\/jimmunol.1602142","article-title":"Cutting edge: selective oral ROCK2 inhibitor reduces clinical scores in patients with psoriasis Vulgaris and normalizes skin pathology via concurrent regulation of IL-17 and IL-10","volume":"198","author":"Zanin-Zhorov","year":"2017","journal-title":"J immunol (Baltim Md : 1950)"},{"issue":"2","key":"10.1016\/j.jnma.2025.08.099_bib0012","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1080\/24725625.2020.1717741","article-title":"Treatment of psoriatic arthritis complicated by systemic lupus erythematosus with the IL-17 blocker secukinumab and an analysis of the serum cytokine profile","volume":"4","author":"Sato","year":"2020","journal-title":"Mod rheumatol case rep"},{"issue":"6","key":"10.1016\/j.jnma.2025.08.099_bib0013","first-page":"603","article-title":"Association between endocrinological, immunological and psychosocial variables in psoriasis patients","volume":"151","author":"Bilgi\u00e7","year":"2016","journal-title":"G Ital Dermatol Venereol"},{"issue":"2","key":"10.1016\/j.jnma.2025.08.099_bib0014","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1016\/j.clinthera.2020.11.016","article-title":"Relationship between vitamin D level and mortality in adults with psoriasis: a retrospective cohort study of NHANES data","volume":"43","author":"Fu","year":"2021","journal-title":"Clin Ther"},{"issue":"18","key":"10.1016\/j.jnma.2025.08.099_bib0015","doi-asserted-by":"crossref","DOI":"10.3390\/nu15183876","article-title":"Metabolic Disorders and Psoriasis: exploring the role of nutritional interventions","volume":"15","author":"Cintoni","year":"2023","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jnma.2025.08.099_bib0016","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s41927-024-00450-2","article-title":"The role of C-reactive protein and genetic predisposition in the risk of psoriasis: results from a national prospective cohort","volume":"8","author":"Li","year":"2024","journal-title":"BMC rheumatol"},{"issue":"3","key":"10.1016\/j.jnma.2025.08.099_bib0017","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s00403-024-02823-6","article-title":"Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in psoriasis: a systematic review and meta-analysis","volume":"316","author":"Ye","year":"2024","journal-title":"Arch Dermatol Res"},{"issue":"1","key":"10.1016\/j.jnma.2025.08.099_bib0018","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12865-021-00454-4","article-title":"Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and other hematological parameters in psoriasis patients","volume":"22","author":"Wang","year":"2021","journal-title":"BMC Immunol"},{"issue":"38","key":"10.1016\/j.jnma.2025.08.099_bib0019","doi-asserted-by":"crossref","first-page":"41370","DOI":"10.18632\/oncotarget.5629","article-title":"Prognostic significance of the combination of preoperative hemoglobin, albumin, lymphocyte and platelet in patients with gastric carcinoma: a retrospective cohort study","volume":"6","author":"Chen","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.jnma.2025.08.099_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.70470\/SHIFAA\/2023\/007","article-title":"Epigenetic modifications as predictive biomarkers for cardiovascular disease: a longitudinal study on DNA methylation patterns and disease risk","volume":"2023","author":"Burhanuddin","year":"2023","journal-title":"SHIFAA"},{"issue":"1","key":"10.1016\/j.jnma.2025.08.099_bib0021","doi-asserted-by":"crossref","first-page":"81","DOI":"10.7150\/jca.27210","article-title":"The hemoglobin, albumin, lymphocyte, and platelet (HALP) score is a novel significant prognostic factor for patients with metastatic prostate cancer undergoing cytoreductive radical prostatectomy","volume":"10","author":"Guo","year":"2019","journal-title":"J Cancer"},{"issue":"2","key":"10.1016\/j.jnma.2025.08.099_bib0022","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1002\/ehf2.14662","article-title":"Association between haemoglobin, albumin, lymphocytes, and platelets and mortality in patients with heart failure","volume":"11","author":"Liu","year":"2024","journal-title":"ESC heart fail"},{"key":"10.1016\/j.jnma.2025.08.099_bib0023","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1173399","article-title":"Association of hemoglobin, albumin, lymphocyte, and platelet score with risk of cerebrovascular, cardiovascular, and all-cause mortality in the general population: results from the NHANES 1999-2018","volume":"14","author":"Pan","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.jnma.2025.08.099_bib0024","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2147\/CIA.S432885","article-title":"Low HALP (Hemoglobin, Albumin, Lymphocyte, and Platelet) score increases the risk of post-stroke cognitive impairment: a multicenter cohort study","volume":"19","author":"Zuo","year":"2024","journal-title":"Clin Interv Aging"},{"issue":"11","key":"10.1016\/j.jnma.2025.08.099_bib0025","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1093\/ndt\/gfad089","article-title":"Interaction effect of psoriasis and chronic kidney disease on the risk of all-cause mortality: a prospective cohort study of NHANES data","volume":"38","author":"Lu","year":"2023","journal-title":"Nephrol Dial Transpl"},{"key":"10.1016\/j.jnma.2025.08.099_bib0026","doi-asserted-by":"crossref","first-page":"73","DOI":"10.58496\/BJML\/2023\/012","article-title":"Diagnosis of HIV (AIDS) by using deep learning and machine learning","volume":"2023","year":"2023","journal-title":"Babylon J Mach Learn"},{"issue":"7","key":"10.1016\/j.jnma.2025.08.099_bib0027","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1001\/jamadermatol.2022.1609","article-title":"Association between psoriasis and nonalcoholic fatty liver disease among outpatient US adults","volume":"158","author":"Ruan","year":"2022","journal-title":"JAMA Dermatol"},{"issue":"10281","key":"10.1016\/j.jnma.2025.08.099_bib0028","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","volume":"397","author":"Griffiths","year":"2021","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.jnma.2025.08.099_bib0029","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1111\/bjd.20643","article-title":"Lesional activation of T(c) 17 cells in Beh\u00e7et disease and psoriasis supports HLA class I-mediated autoimmune responses","volume":"185","author":"Vural","year":"2021","journal-title":"Br J Dermatol"},{"issue":"3","key":"10.1016\/j.jnma.2025.08.099_bib0030","doi-asserted-by":"crossref","DOI":"10.1111\/dth.13344","article-title":"Short-term effectiveness and safety in real clinical practice","volume":"33","author":"Rodriguez Fernandez-Freire","year":"2020","journal-title":"Dermatol Ther"},{"issue":"5","key":"10.1016\/j.jnma.2025.08.099_bib0031","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1056\/NEJMra0804595","volume":"361","author":"Nestle","year":"2009","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.jnma.2025.08.099_bib0032","article-title":"Lymphocyte mass cytometry identifies a CD3-CD4+ cell subset with a potential role in psoriasis","volume":"4","author":"Guo","year":"2019","journal-title":"JCI insight"},{"key":"10.1016\/j.jnma.2025.08.099_bib0033","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/1741-7015-10-82","article-title":"Gender and the treatment of immune-mediated chronic inflammatory diseases: rheumatoid arthritis, inflammatory bowel disease and psoriasis: an observational study","volume":"10","author":"Lesuis","year":"2012","journal-title":"BMC Med"},{"key":"10.1016\/j.jnma.2025.08.099_bib0034","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.cca.2015.04.023","article-title":"Is enhanced platelet activation the missing link leading to increased cardiovascular risk in psoriasis?","volume":"446","author":"Chandrashekar","year":"2015","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jnma.2025.08.099_bib0035","first-page":"8","article-title":"Measuring the effectiveness of AI tools in clinical research and writing: a case study in healthcare","volume":"2024","year":"2024","journal-title":"Mesop J Artif Intell Healthc"},{"key":"10.1016\/j.jnma.2025.08.099_bib0036","doi-asserted-by":"crossref","first-page":"149","DOI":"10.58496\/BJML\/2024\/015","article-title":"Advancements in machine learning and deep learning for early diagnosis of chronic kidney diseases: a comprehensive review","volume":"2024","year":"2024","journal-title":"Babylon J Mach Learn"},{"key":"10.1016\/j.jnma.2025.08.099_bib0037","first-page":"57","article-title":"The benefit of artificial intelligence in the analysis of malignant brain diseases: a mini review","volume":"2023","year":"2023","journal-title":"Mesop J Artif Intell Healthc"}],"container-title":["Journal of the National Medical Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0027968425002998?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0027968425002998?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T12:33:13Z","timestamp":1768480393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0027968425002998"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0027968425002998"],"URL":"https:\/\/doi.org\/10.1016\/j.jnma.2025.08.099","relation":{},"ISSN":["0027-9684"],"issn-type":[{"value":"0027-9684","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between hemoglobin albumin lymphocyte and platelet (HALP) score and psoriasis: Evidence from NHANES","name":"articletitle","label":"Article Title"},{"value":"Journal of the National Medical Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnma.2025.08.099","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 National Medical Association. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}