{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T07:40:47Z","timestamp":1770018047732,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2004,10]]},"DOI":"10.1016\/j.jns.2004.06.019","type":"journal-article","created":{"date-parts":[[2004,8,27]],"date-time":"2004-08-27T23:22:12Z","timestamp":1093648932000},"page":"57-64","source":"Crossref","is-referenced-by-count":32,"title":["Microarray analysis in Tourette syndrome postmortem putamen"],"prefix":"10.1016","volume":"225","author":[{"given":"John J.","family":"Hong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher R.","family":"Loiselle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dustin Y.","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin G.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harvey S.","family":"Singer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2004.06.019_bib1","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1002\/1531-8257(200011)15:6<1051::AID-MDS1001>3.0.CO;2-L","article-title":"Current issues in Tourette syndrome","volume":"15","author":"Singer","year":"2000","journal-title":"Mov. Disord."},{"issue":"Suppl. 1","key":"10.1016\/j.jns.2004.06.019_bib2","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1016\/S0387-7604(03)90012-X","article-title":"Neurobiology of Tourette's syndrome: concepts of neuroanatomic localization and neurochemical abnormalities","volume":"25","author":"Singer","year":"2003","journal-title":"Brain Dev."},{"key":"10.1016\/j.jns.2004.06.019_bib3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00005792-199101000-00002","article-title":"Tourette syndrome and other tic disorders. Diagnosis, pathophysiology, and treatment","volume":"70","author":"Singer","year":"1991","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jns.2004.06.019_bib4","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0733-8619(05)70318-2","article-title":"Neurobiology of Tourette syndrome","volume":"15","author":"Singer","year":"1997","journal-title":"Neurol. Clin."},{"key":"10.1016\/j.jns.2004.06.019_bib5","doi-asserted-by":"crossref","first-page":"E15","DOI":"10.1371\/journal.pbio.0000015","article-title":"Microarray analysis: genome-scale hypothesis scanning","volume":"1","author":"Gibson","year":"2003","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jns.2004.06.019_bib6","doi-asserted-by":"crossref","first-page":"437","DOI":"10.2174\/1566524033479690","article-title":"The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia","volume":"3","author":"Lehrmann","year":"2003","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.jns.2004.06.019_bib7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0896-6273(00)00085-4","article-title":"Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex","volume":"28","author":"Mirnics","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.jns.2004.06.019_bib8","first-page":"213","article-title":"Functional neuroanatomy of Tourette syndrome. Limbic\u2013motor interactions studied with FDG PET","volume":"58","author":"Stoetter","year":"1992","journal-title":"Adv. Neurol."},{"key":"10.1016\/j.jns.2004.06.019_bib9","series-title":"Nuclear Medicine: The State of the Art of Nuclear Medicine in Europe","first-page":"243","article-title":"Brain perfusion patterns with 99Tcm-HMPAO\/SPECT in patients with Gilles de la Tourette syndrome\u2014short report","author":"Hall","year":"1991"},{"key":"10.1016\/j.jns.2004.06.019_bib10","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1212\/WNL.43.5.950","article-title":"Volumetric MRI changes in basal ganglia of children with Tourette's syndrome","volume":"43","author":"Singer","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2004.06.019_bib11","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1001\/archpsyc.55.4.326","article-title":"A functional magnetic resonance imaging study of tic suppression in Tourette syndrome","volume":"55","author":"Peterson","year":"1998","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jns.2004.06.019_bib12","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/1531-8249(199909)46:3<425::AID-ANA22>3.0.CO;2-O","article-title":"Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays","volume":"46","author":"Whitney","year":"1999","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jns.2004.06.019_bib13","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/4434","article-title":"Expression profiling using cDNA microarrays","volume":"21","author":"Duggan","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jns.2004.06.019_bib14","first-page":"127","article-title":"Assembly and use of a broadly applicable neural cDNA microarray","volume":"18","author":"Barrett","year":"2001","journal-title":"Restor. Neurol. Neurosci."},{"key":"10.1016\/j.jns.2004.06.019_bib15","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0361-9230(01)00522-6","article-title":"Application of cDNA microarrays to examine gene expression differences in schizophrenia","volume":"55","author":"Vawter","year":"2001","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.jns.2004.06.019_bib16","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1525-1578(10)60455-2","article-title":"Analysis of microarray data using Z score transformation","volume":"5","author":"Cheadle","year":"2003","journal-title":"J. Mol. Diagn."},{"key":"10.1016\/j.jns.2004.06.019_bib17","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.jns.2004.06.019_bib18","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jns.2003.12.006","article-title":"Increased prefrontal D2 protein in Tourette syndrome: a postmortem analysis of frontal cortex and striatum","volume":"219","author":"Minzer","year":"2004","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.jns.2004.06.019_bib19","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1006\/jaut.2001.0577","article-title":"ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies","volume":"18","author":"Miao","year":"2002","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jns.2004.06.019_bib20","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1126\/science.1065817","article-title":"A phosphatase associated with metastasis of colorectal cancer","volume":"294","author":"Saha","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.jns.2004.06.019_bib21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0925-4773(98)00119-1","article-title":"Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases, LAR, RPTPdelta and RPTPsigma in the mouse","volume":"77","author":"Schaapveld","year":"1998","journal-title":"Mech. Dev."},{"key":"10.1016\/j.jns.2004.06.019_bib22","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0014-2999(97)00100-3","article-title":"Functional link between tyrosine phosphorylation and human serotonin transporter gene expression","volume":"325","author":"Prasad","year":"1997","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jns.2004.06.019_bib23","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1460-9568.1997.tb01356.x","article-title":"5-Hydroxytryptamine induces TIS8\/egr-1 and c-fos expression in PC12 cells. Involvement of tyrosine protein phosphorylation","volume":"9","author":"Humblot","year":"1997","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.jns.2004.06.019_bib24","doi-asserted-by":"crossref","first-page":"5630","DOI":"10.1523\/JNEUROSCI.20-15-05630.2000","article-title":"The dopamine\/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway","volume":"20","author":"Paul","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jns.2004.06.019_bib25","doi-asserted-by":"crossref","first-page":"5546","DOI":"10.1523\/JNEUROSCI.21-15-05546.2001","article-title":"Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane","volume":"21","author":"Dunah","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jns.2004.06.019_bib26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S0304-3940(02)00750-4","article-title":"Association between the low molecular weight cytosolic acid phosphatase gene ACP1*A and comorbid features of Tourette syndrome","volume":"330","author":"Bottini","year":"2002","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.jns.2004.06.019_bib27","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0006-3223(94)00161-U","volume":"37","author":"Brett","year":"1995","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jns.2004.06.019_bib28","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1001\/archneur.1984.04050180078022","article-title":"CSF cholinesterase activity in Gilles de la Tourette's syndrome","volume":"41","author":"Singer","year":"1984","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.jns.2004.06.019_bib29","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/ana.410270415","article-title":"Tourette's syndrome: a neurochemical analysis of postmortem cortical brain tissue","volume":"27","author":"Singer","year":"1990","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jns.2004.06.019_bib30","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/0022-510X(94)00211-6","article-title":"Second messenger systems in Tourette's syndrome","volume":"128","author":"Singer","year":"1995","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.jns.2004.06.019_bib31","doi-asserted-by":"crossref","first-page":"32875","DOI":"10.1074\/jbc.M010400200","article-title":"Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II","volume":"276","author":"Si","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jns.2004.06.019_bib32","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/35000501","article-title":"Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling","volume":"403","author":"Alizadeh","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.jns.2004.06.019_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1097-4547(20000101)59:1<1::AID-JNR1>3.0.CO;2-2","article-title":"High throughput analysis of gene expression in the human brain","volume":"59","author":"Colantuoni","year":"2000","journal-title":"J. Neurosci. Res."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X04002126?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X04002126?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T13:54:54Z","timestamp":1549288494000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X04002126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":33,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["S0022510X04002126"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2004.06.019","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,10]]}}}