{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T15:36:21Z","timestamp":1778772981769,"version":"3.51.4"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.jns.2005.07.013","type":"journal-article","created":{"date-parts":[[2005,10,12]],"date-time":"2005-10-12T11:09:17Z","timestamp":1129115357000},"page":"45-52","source":"Crossref","is-referenced-by-count":45,"title":["Increased intracranial volume in Parkinson's disease"],"prefix":"10.1016","volume":"239","author":[{"given":"Katja","family":"Krabbe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merete","family":"Karlsborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lene","family":"Werdelin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesper","family":"Mehlsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik B.W.","family":"Larsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf B.","family":"Paulson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1\u20133","key":"10.1016\/j.jns.2005.07.013_bib1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0022-510X(89)90219-0","article-title":"Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy\u2013Drager syndrome)","volume":"94","author":"Papp","year":"1989","journal-title":"J Neurol Sci"},{"issue":"2","key":"10.1016\/j.jns.2005.07.013_bib2","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/ana.410430205","article-title":"Depletion of catecholaminergic neurons of the rostral ventrolateral medulla in multiple systems atrophy with autonomic failure","volume":"43","author":"Benarroch","year":"1998","journal-title":"Ann Neurol"},{"issue":"4","key":"10.1016\/j.jns.2005.07.013_bib3","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s004010051008","article-title":"Multiple system atrophy with remarkable frontal lobe atrophy","volume":"97","author":"Konagaya","year":"1999","journal-title":"Acta Neuropathol (Berl)"},{"issue":"2","key":"10.1016\/j.jns.2005.07.013_bib4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/mds.870120203","article-title":"Multiple system atrophy: a review of 203 pathologically proven cases","volume":"12","author":"Wenning","year":"1997","journal-title":"Mov Disord"},{"key":"10.1016\/j.jns.2005.07.013_bib5","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/j.1468-1331.1996.tb00248.x","article-title":"Decrease in neuronal density in the cerebral cortex in multiple system atrophy","volume":"3","author":"Spargo","year":"1996","journal-title":"Eur J Neurol"},{"issue":"1","key":"10.1016\/j.jns.2005.07.013_bib6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s004010000273","article-title":"Primary involvement of the motor area in association with the nigrostriatal pathway in multiple system atrophy: neuropathological and morphometric evaluations","volume":"101","author":"Su","year":"2001","journal-title":"Acta Neuropathol (Berl)"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib7","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1006\/brcg.1995.1261","article-title":"The neuropathology of parkinsonism: an overview","volume":"28","author":"Cornford","year":"1995","journal-title":"Brain Cogn"},{"issue":"6","key":"10.1016\/j.jns.2005.07.013_bib8","first-page":"304","article-title":"Regional brain atrophy in idiopathic Parkinson's disease and diffuse Lewy body disease","volume":"7","author":"Double","year":"1996","journal-title":"Dementia"},{"issue":"Pt 11","key":"10.1016\/j.jns.2005.07.013_bib9","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1093\/brain\/awf251","article-title":"Clinical correlates of selective pathology in the amygdala of patients with Parkinson's disease","volume":"125","author":"Harding","year":"2002","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib10","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/BF03159935","article-title":"Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway","volume":"14","author":"Jellinger","year":"1991","journal-title":"Mol Chem Neuropathol"},{"issue":"10","key":"10.1016\/j.jns.2005.07.013_bib11","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1002\/mds.10502","article-title":"Voxel-based morphometry detects cortical atrophy in the Parkinson variant of multiple system atrophy","volume":"18","author":"Brenneis","year":"2003","journal-title":"Mov Disord"},{"issue":"1","key":"10.1016\/j.jns.2005.07.013_bib12","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/1531-8249(199901)45:1<65::AID-ART12>3.0.CO;2-1","article-title":"Magnetic resonance imaging-based volumetry differentiates idiopathic Parkinson's syndrome from multiple system atrophy and progressive supranuclear palsy","volume":"45","author":"Schulz","year":"1999","journal-title":"Ann Neurol"},{"issue":"10","key":"10.1016\/j.jns.2005.07.013_bib13","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1001\/archneur.60.10.1431","article-title":"In vivo voxel-based morphometry in multiple system atrophy of the cerebellar type","volume":"60","author":"Specht","year":"2003","journal-title":"Arch Neurol"},{"issue":"1","key":"10.1016\/j.jns.2005.07.013_bib14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1001\/archneur.56.1.33","article-title":"Diagnostic criteria for Parkinson disease","volume":"56","author":"Gelb","year":"1999","journal-title":"Arch Neurol"},{"issue":"6","key":"10.1016\/j.jns.2005.07.013_bib15","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/BF02309628","article-title":"Consensus statement on the diagnosis of multiple system atrophy. American Autonomic Society and American Academy of Neurology","volume":"8","author":"Gilman","year":"1998","journal-title":"Clin Auton Res"},{"issue":"5","key":"10.1016\/j.jns.2005.07.013_bib16","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1212\/WNL.17.5.427","article-title":"Parkinsonism: onset, progression and mortality","volume":"17","author":"Hoehn","year":"1967","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib17","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state.\u201d A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"issue":"4","key":"10.1016\/j.jns.2005.07.013_bib18","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0197-4580(01)00217-2","article-title":"Effects of age on tissues and regions of the cerebrum and cerebellum","volume":"22","author":"Jernigan","year":"2001","journal-title":"Neurobiol Aging"},{"issue":"1 Pt 1","key":"10.1016\/j.jns.2005.07.013_bib19","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1006\/nimg.2001.0786","article-title":"A voxel-based morphometric study of ageing in 465 normal adult human brains","volume":"14","author":"Good","year":"2001","journal-title":"Neuroimage"},{"issue":"5","key":"10.1016\/j.jns.2005.07.013_bib20","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1159\/000114960","article-title":"Nerve cell loss with aging in the putamen","volume":"17","author":"Bugiani","year":"1978","journal-title":"Eur Neurol"},{"issue":"2","key":"10.1016\/j.jns.2005.07.013_bib21","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1006\/nlme.1995.1013","article-title":"Age, gender, and hemispheric differences in human striatum: a quantitative review and new data from in vivo MRI morphometry","volume":"63","author":"Raz","year":"1995","journal-title":"Neurobiol Learn Mem"},{"issue":"Pt 5","key":"10.1016\/j.jns.2005.07.013_bib22","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1093\/brain\/114.5.2283","article-title":"Ageing and Parkinson's disease: substantia nigra regional selectivity","volume":"114","author":"Fearnley","year":"1991","journal-title":"Brain"},{"issue":"11","key":"10.1016\/j.jns.2005.07.013_bib23","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1212\/WNL.39.11.1524","article-title":"Magnetic resonance imaging in Parkinson's disease and parkinsonian syndromes","volume":"39","author":"Stern","year":"1989","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.jns.2005.07.013_bib24","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1136\/jnnp.65.1.65","article-title":"Clinical usefulness of magnetic resonance imaging in multiple system atrophy","volume":"65","author":"Schrag","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib25","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1212\/WNL.54.3.697","article-title":"Differentiation of atypical parkinsonian syndromes with routine MRI","volume":"54","author":"Schrag","year":"2000","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.jns.2005.07.013_bib26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/mds.870110207","article-title":"Olivopontocerebellar pathology in multiple system atrophy","volume":"11","author":"Wenning","year":"1996","journal-title":"Mov Disord"},{"issue":"5","key":"10.1016\/j.jns.2005.07.013_bib27","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1159\/000115172","article-title":"Loss of striatal neurons in Parkinson's disease: a cytometric study","volume":"19","author":"Bugiani","year":"1980","journal-title":"Eur Neurol"},{"key":"10.1016\/j.jns.2005.07.013_bib28","first-page":"1","article-title":"Morphology of the basal ganglia in Parkinson's disease","volume":"62","author":"Bottcher","year":"1975"},{"key":"10.1016\/j.jns.2005.07.013_bib29","first-page":"13","article-title":"Diminished subcortical nuclei volumes in Parkinson's disease by MR imaging","volume":"40","author":"Lisanby","year":"1993","journal-title":"J Neural Transm Suppl"},{"issue":"Pt 3","key":"10.1016\/j.jns.2005.07.013_bib30","first-page":"1363","article-title":"Nerve cell loss in the thalamus in Alzheimer's disease and Parkinson's disease","volume":"114","author":"Xuereb","year":"1991","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib31","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s00234-001-0713-7","article-title":"Characteristic MRI findings in multiple system atrophy: comparison of the three subtypes","volume":"44","author":"Naka","year":"2002","journal-title":"Neuroradiology"},{"issue":"7","key":"10.1016\/j.jns.2005.07.013_bib32","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/mds.10444","article-title":"Parkinson's disease is associated with hippocampal atrophy","volume":"18","author":"Camicioli","year":"2003","journal-title":"Mov Disord"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib33","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1212\/WNL.46.3.678","article-title":"Hippocampal volumes in Alzheimer's disease, Parkinson's disease with and without dementia, and in vascular dementia: an MRI study","volume":"46","author":"Laakso","year":"1996","journal-title":"Neurology"},{"issue":"5","key":"10.1016\/j.jns.2005.07.013_bib34","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1054\/jocn.2001.1071","article-title":"Olfactory function in Parkinsonian syndromes","volume":"9","author":"Muller","year":"2002","journal-title":"J Clin Neurosci"},{"issue":"4","key":"10.1016\/j.jns.2005.07.013_bib35","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/00008506-200110000-00001","article-title":"The amygdala and cardiovascular control","volume":"13","author":"Cechetto","year":"2001","journal-title":"J Neurosurg Anesthesiol"},{"issue":"4\u20135","key":"10.1016\/j.jns.2005.07.013_bib36","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1023\/A:1025067912199","article-title":"Brainstem in multiple system atrophy: clinicopathological correlations","volume":"23","author":"Benarroch","year":"2003","journal-title":"Cell Mol Neurobiol"},{"issue":"2","key":"10.1016\/j.jns.2005.07.013_bib37","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/mds.20289","article-title":"No global loss of neocortical neurons in Parkinson's disease: a quantitative stereological study","volume":"20","author":"Pedersen","year":"2005","journal-title":"Mov Disord"},{"issue":"11","key":"10.1016\/j.jns.2005.07.013_bib38","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1136\/jnnp.52.11.1221","article-title":"Magnetic resonance imaging in dementia of Parkinson's disease","volume":"52","author":"Huber","year":"1989","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"10.1016\/j.jns.2005.07.013_bib39","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0022-510X(99)00308-1","article-title":"Cerebral atrophy in multiple system atrophy by MRI","volume":"173","author":"Horimoto","year":"2000","journal-title":"J Neurol Sci"},{"issue":"4","key":"10.1016\/j.jns.2005.07.013_bib40","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/jon199994201","article-title":"Does an increase in sulcal or ventricular fluid predict where brain tissue is lost?","volume":"9","author":"Symonds","year":"1999","journal-title":"J Neuroimaging"},{"issue":"10","key":"10.1016\/j.jns.2005.07.013_bib41","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1212\/WNL.42.10.1894","article-title":"Parkinson's disease in twins studied with 18F-dopa and positron emission tomography","volume":"42","author":"Burn","year":"1992","journal-title":"Neurology"},{"issue":"Suppl 3","key":"10.1016\/j.jns.2005.07.013_bib42","first-page":"III\/15","article-title":"Spectrum of phenotypes and genotypes in Parkinson's disease","volume":"249","author":"Riess","year":"2002","journal-title":"J Neurol"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib43","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/ajmg.10335","article-title":"Segregation analysis of Parkinson disease revealing evidence for a major causative gene","volume":"109","author":"Maher","year":"2002","journal-title":"Am J Med Genet"},{"issue":"9","key":"10.1016\/j.jns.2005.07.013_bib44","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S1474-4422(03)00501-5","article-title":"The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?","volume":"2","author":"Di Monte","year":"2003","journal-title":"Lancet Neurol"},{"issue":"1","key":"10.1016\/j.jns.2005.07.013_bib45","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/mds.10078","article-title":"In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain","volume":"17","author":"Ling","year":"2002","journal-title":"Mov Disord"},{"issue":"20","key":"10.1016\/j.jns.2005.07.013_bib46","doi-asserted-by":"crossref","first-page":"11050","DOI":"10.1073\/pnas.200033797","article-title":"Measuring the thickness of the human cerebral cortex from magnetic resonance images","volume":"97","author":"Fischl","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.jns.2005.07.013_bib47","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/cercor\/bhg087","article-title":"Automatically parcellating the human cerebral cortex","volume":"14","author":"Fischl","year":"2004","journal-title":"Cereb Cortex"},{"issue":"3","key":"10.1016\/j.jns.2005.07.013_bib48","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0896-6273(02)00569-X","article-title":"Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain","volume":"33","author":"Fischl","year":"2002","journal-title":"Neuron"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X05002698?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X05002698?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T07:53:47Z","timestamp":1586505227000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X05002698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0022510X05002698"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2005.07.013","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}