{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:31:25Z","timestamp":1791217885869,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1016\/j.jns.2006.07.001","type":"journal-article","created":{"date-parts":[[2006,9,7]],"date-time":"2006-09-07T13:12:45Z","timestamp":1157634765000},"page":"62-70","source":"Crossref","is-referenced-by-count":29,"title":["Cold-induced sweating syndrome A report of two cases and demonstration of genetic heterogeneity"],"prefix":"10.1016","volume":"250","author":[{"given":"A.F.","family":"Hahn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.L.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.M.","family":"Knappskog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Boman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.G.","family":"McLeod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2006.07.001_bib1","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/S0140-6736(78)91805-6","article-title":"Cold-induced profuse sweating on back and chest: a new genetic entity?","volume":"2","author":"Sohar","year":"1978","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2006.07.001_bib2","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1212\/WNL.56.2.254","article-title":"Basal forebrain malformation with hyperhidrosis and hypothermia: variant of Shapiro's syndrome","volume":"56","author":"Klein","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2006.07.001_bib3","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1086\/346120","article-title":"Cold-induced sweating syndrome is caused by mutations in the CRFL1 gene","volume":"72","author":"Knappskog","year":"2003","journal-title":"Am J Hum Genet"},{"issue":"Suppl 1","key":"10.1016\/j.jns.2006.07.001_bib4","first-page":"79","article-title":"Cold-induced sweating syndrome \u2014 a report of two cases","volume":"238","author":"Hahn","year":"2005","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.jns.2006.07.001_bib5","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/ana.410210602","article-title":"Disorders of the autonomic system: Part 2. Investigation and treatment","volume":"21","author":"McLeod","year":"1987","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jns.2006.07.001_bib6","series-title":"Peripheral Neuropathy","first-page":"729","article-title":"Quantitation of autonomic function","author":"Low","year":"1993"},{"key":"10.1016\/j.jns.2006.07.001_bib7","series-title":"Peripheral Neuropathy","first-page":"514","article-title":"Pathologic alterations in nerves","author":"Dyck","year":"1993"},{"key":"10.1016\/j.jns.2006.07.001_bib8","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1038\/78765","article-title":"CLF associates with CLC to form a functional heteromeric ligand for CNTF receptor complex","volume":"3","author":"Elson","year":"2000","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jns.2006.07.001_bib9","doi-asserted-by":"crossref","first-page":"10068","DOI":"10.1073\/pnas.0509598103","article-title":"Inactivation of cardiotrophin-like cytokine, a second ligand for CNTF receptor, leads to cold induced sweating syndrome in a patient","volume":"103","author":"Rousseau","year":"2006","journal-title":"PNAS"},{"key":"10.1016\/j.jns.2006.07.001_bib10","doi-asserted-by":"crossref","first-page":"22476","DOI":"10.1074\/jbc.M101681200","article-title":"Signaling pathways recruited by the cardiotrophin-like cytokine\/cytokine-like factor-1 composite cytokine","volume":"276","author":"Leli\u00e8vre","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jns.2006.07.001_bib11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0896-6273(93)90245-M","article-title":"The \u03b1 component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development","volume":"10","author":"Ip","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.jns.2006.07.001_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj20030407","article-title":"Principles of interleukin (IL)-6-type cytokine signaling and its regulation","volume":"374","author":"Heinrich","year":"2003","journal-title":"Biochem J"},{"key":"10.1016\/j.jns.2006.07.001_bib13","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0092-8674(95)90172-8","article-title":"Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth","volume":"83","author":"DeChiara","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.jns.2006.07.001_bib14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/365027a0","article-title":"Disruption of the CNTF gene results in motor neuron degeneration","volume":"365","author":"Masu","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.jns.2006.07.001_bib15","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/ng0594-79","article-title":"A null mutation in the human CNTF gene is not causally related to neurological diseases","volume":"1","author":"Takahashi","year":"1994","journal-title":"Nat Genet"},{"key":"10.1016\/j.jns.2006.07.001_bib16","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0960-9822(99)80266-8","article-title":"Suckling defect in mice lacking the soluble haemopoietin receptor NR6","volume":"9","author":"Alexander","year":"1999","journal-title":"Curr Biol"},{"key":"10.1016\/j.jns.2006.07.001_bib17","doi-asserted-by":"crossref","first-page":"8854","DOI":"10.1523\/JNEUROSCI.23-26-08854.2003","article-title":"Cardiotrophin-like cytokine\/cytokine-like factor 1 is an essential trophic factor for lumbar and facial motorneurons in vivo","volume":"23","author":"Forger","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.jns.2006.07.001_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1478-811X-3-1","article-title":"clc is co-expressed with clf or cntfr in developing mouse muscles","volume":"3","author":"de Bovis","year":"2005","journal-title":"Cell Commun Signal"},{"key":"10.1016\/j.jns.2006.07.001_bib19","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/brain\/92.2.423","article-title":"Spontaneous recurrent hypothermia accompanying agenesis of the corpus callosum","volume":"92","author":"Shapiro","year":"1969","journal-title":"Brain"},{"key":"10.1016\/j.jns.2006.07.001_bib20","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1001\/archneur.1989.00520370055019","article-title":"Altered norepinephrine metabolism in Shapiro's syndrome","volume":"46","author":"Sanfield","year":"1989","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jns.2006.07.001_bib21","first-page":"235","article-title":"Clonidine therapy for Shapiro's syndrome","volume":"82","author":"Walker","year":"1992","journal-title":"Q J Med"},{"key":"10.1016\/j.jns.2006.07.001_bib22","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1152\/jappl.1953.5.8.399","article-title":"Dermatomal recruitment of sweating","volume":"5","author":"Randall","year":"1953","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.jns.2006.07.001_bib23","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev.ph.50.030188.003025","article-title":"Peripheral sympathetic neural activity in conscious humans","volume":"50","author":"Wallin","year":"1988","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.jns.2006.07.001_bib24","series-title":"Clinical Autonomic Disorders","first-page":"83","article-title":"Autonomic regulation of temperature and sweating","author":"Ogawa","year":"1997"},{"key":"10.1016\/j.jns.2006.07.001_bib25","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1749-6632.1998.tb08319.x","article-title":"Hypothalamic neurons. Mechanisms of sensitivity to temperature","volume":"856","author":"Boulant","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jns.2006.07.001_bib26","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S1566-0702(00)00216-2","article-title":"Neuronal circuitries involved in thermoregulation","volume":"85","author":"Nagashima","year":"2000","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.jns.2006.07.001_bib27","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/72131","article-title":"Thermosensory activation of insular cortex","volume":"3","author":"Craig","year":"2000","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jns.2006.07.001_bib28","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.neuroscience.2005.06.028","article-title":"Evidence that peripheral rather than intracranial thermal signals induce thermoregulation","volume":"135","author":"Bratincs\u00e1k","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.jns.2006.07.001_bib29","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/nrn1141","article-title":"ThermoTRP channels and beyond: mechanisms of temperature sensation","volume":"4","author":"Patapoutian","year":"2003","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.jns.2006.07.001_bib30","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s00424-005-1438-y","article-title":"TRPV channels as thermosensory receptors in epithelial cells","volume":"451","author":"Lee","year":"2005","journal-title":"Pflugers Arch- Eur J Physiol"},{"key":"10.1016\/j.jns.2006.07.001_bib31","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1242\/dev.02189","article-title":"Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp130 signaling","volume":"133","author":"Stanke","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.jns.2006.07.001_bib32","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BFb0034538","article-title":"Alpha-adrenoceptor subclassification","volume":"88","author":"Starke","year":"1981","journal-title":"Rev Physiol Biochem Pharmacol"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X06003297?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X06003297?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T02:24:13Z","timestamp":1555813453000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X06003297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":32,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["S0022510X06003297"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2006.07.001","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}