{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T21:43:12Z","timestamp":1773265392152,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.jns.2008.09.005","type":"journal-article","created":{"date-parts":[[2008,10,6]],"date-time":"2008-10-06T04:10:31Z","timestamp":1223266231000},"page":"79-83","source":"Crossref","is-referenced-by-count":72,"title":["Cardiac parasympathetic dysfunction concurrent with cardiac sympathetic denervation in Parkinson's disease"],"prefix":"10.1016","volume":"276","author":[{"given":"Mamoru","family":"Shibata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Morita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazushi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihiro","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2008.09.005_bib1","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1212\/WNL.47.5.1113","article-title":"Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop","volume":"47","author":"MacKeith","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2008.09.005_bib2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0197-4580(02)00065-9","article-title":"Staging of brain pathology related to sporadic Parkinson's disease","volume":"24","author":"Braak","year":"2003","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jns.2008.09.005_bib3","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1212\/WNL.37.7.1253","article-title":"Parkinson's disease and megacolon: concentric hyaline inclusions (Lewy bodies) in enteric ganglion cells","volume":"37","author":"Kupsky","year":"1987","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2008.09.005_bib4","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF00687767","article-title":"Parkinson's disease: the presence of Lewy bodies in Auerbach's and Meissner's plexuses","volume":"76","author":"Wakabayashi","year":"1988","journal-title":"Acta Neuropathol"},{"issue":"suppl 2","key":"10.1016\/j.jns.2008.09.005_bib5","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000113469","article-title":"Neuropathology of autonomic nervous system in Parkinson's disease","volume":"38","author":"Wakabayashi","year":"1997","journal-title":"Eur Neurol"},{"key":"10.1016\/j.jns.2008.09.005_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1750-3639.2005.tb00097.x","article-title":"Profound cardiac sympathetic denervation occurs in Parkinson's disease","volume":"15","author":"Amino","year":"2005","journal-title":"Brain Pathol"},{"key":"10.1016\/j.jns.2008.09.005_bib7","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/j.1750-3639.2006.00032.x","article-title":"Degeneration of cardiac sympathetic nerve begins in the early disease process of Parkinson's disease","volume":"17","author":"Orimo","year":"2007","journal-title":"Brain Pathol"},{"key":"10.1016\/j.jns.2008.09.005_bib8","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/mds.10461","article-title":"Cardiac MIBG scintigraphy is a sensitive tool for detecting cardiac sympathetic denervation in Parkinson's disease","author":"Courbon","year":"2003","journal-title":"Mov Disord"},{"key":"10.1016\/j.jns.2008.09.005_bib9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jns.2005.10.014","article-title":"Cardiovascular dysautonomia in de novo Parkinson's disease","volume":"241","author":"Oka","year":"2006","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.jns.2008.09.005_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S1353-8020(02)00032-9","article-title":"Are electrophysiological autonomic tests useful in the assessment of dysautonomia in Parkinson's disease?","volume":"9","author":"Zakrzewska-Pniewska","year":"2003","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.jns.2008.09.005_bib11","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S1474-4422(03)00555-6","article-title":"Dysautonomia in Parkinson's disease: neurocardiological abnormalities","volume":"2","author":"Goldstein","year":"2003","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jns.2008.09.005_bib12","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1161\/01.HYP.0000188052.69549.e4","article-title":"Neurocirculatory abnormalities in Parkinson's disease with orthostatic hypotension: independence from Levodopa treatment","volume":"46","author":"Goldstein","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2008.09.005_bib13","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/j.1600-0404.2006.00580.x","article-title":"Orthostatic heart rate variability analysis in idiopathic Parkinson\u2019s disease","volume":"113","author":"Mihci","year":"2006","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.jns.2008.09.005_bib14","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jns.2008.09.005_bib15","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1136\/bmj.4.5892.584","article-title":"Cardiac denervation in diabetes","volume":"4","author":"Wheeler","year":"1973","journal-title":"Br Med J"},{"key":"10.1016\/j.jns.2008.09.005_bib16","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/oxfordjournals.eurheartj.a014868","article-title":"Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation, and clinical use","volume":"17","year":"1996","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jns.2008.09.005_bib17","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1136\/jnnp.63.5.584","article-title":"Prevalence of orthostatic hypotension in Parkinson's disease","volume":"63","author":"Senard","year":"1997","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jns.2008.09.005_bib18","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/ana.20160","article-title":"Idiopathic hyposmia as a preclinical sign of Parkinson's disease","volume":"56","author":"Ponsen","year":"2004","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jns.2008.09.005_bib19","doi-asserted-by":"crossref","first-page":"338","DOI":"10.7326\/0003-4819-133-5-200009050-00009","article-title":"Cardiac sympathetic denervation in Parkinson's disease","volume":"133","author":"Goldstein","year":"2000","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jns.2008.09.005_bib20","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1212\/WNL.58.8.1247","article-title":"Orthostatic hypotension from denervation in Parkinson's disease","volume":"58","author":"Goldstein","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2008.09.005_bib21","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1046\/j.1468-1331.2000.00127.x","article-title":"Heart rate variability in patients with untreated Parkinson's disease","volume":"7","author":"Kallio","year":"2000","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.jns.2008.09.005_bib22","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S1353-8020(02)00032-9","article-title":"Are electrophysiological autonomic tests useful in the assessment of dysautonomia in Parkinson's disease?","volume":"9","author":"Zakrzewska-Pniewska","year":"2003","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.jns.2008.09.005_bib23","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0304-3940(95)11489-J","article-title":"Nigrostriatal dopamine system mediates baroreflex sensitivity in rats","volume":"190","author":"Lu","year":"1995","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jns.2008.09.005_bib24","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/mds.20744","article-title":"Beat-to-beat blood pressure analysis after premature ventricular contraction indicates sensitive baroreceptor dysfunction in Parkinson's disease","volume":"21","author":"Haensch","year":"2006","journal-title":"Mov Disord"},{"key":"10.1016\/j.jns.2008.09.005_bib25","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1212\/01.WNL.0000042087.07133.87","article-title":"Preservation of brachiomotor neurons of the nucleus ambiguus in multiple system atrophy","volume":"60","author":"Benarroch","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2008.09.005_bib26","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1212\/01.wnl.0000196638.98781.bb","article-title":"Involvement of vagal autonomic nuclei in multiple system atrophy and Lewy body diseases","volume":"66","author":"Benarroch","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2008.09.005_bib27","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/cne.903270408","article-title":"Localization of cardiac vagal preganglionic motoneurones in the rat: immunohistochemical evidence of synaptic inputs containing 5-hydroxytryptamine","volume":"327","author":"Izzo","year":"1993","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.jns.2008.09.005_bib28","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/1096-9861(20000904)424:4<588::AID-CNE3>3.0.CO;2-7","article-title":"Nucleus ambiguus projections to cardiac ganglia of rat atria: an antegrade tracing study","volume":"424","author":"Cheng","year":"2000","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.jns.2008.09.005_bib29","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1212\/WNL.52.6.1269","article-title":"Lewy body-type degeneration in cardiac plexus in Parkinson's and incidental Lewy body disease","volume":"52","author":"Iwanaga","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2008.09.005_bib30","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1440-1827.2004.01680.x","article-title":"Lewy bodies in the sinoatrial nodal ganglion: clinicopathological studies","volume":"54","author":"Okada","year":"2004","journal-title":"Pathol Int"},{"key":"10.1016\/j.jns.2008.09.005_bib31","article-title":"Cardiac denervation occurs independent of orthostatic hypotension and impaired heart rate variability in Parkinson's disease","author":"Haensch","year":"2008","journal-title":"Parkinsonism Relat Disord"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X08004541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X08004541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T08:17:48Z","timestamp":1557821868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X08004541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":31,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0022510X08004541"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2008.09.005","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}