{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T14:50:40Z","timestamp":1772895040242,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1016\/j.jns.2009.09.011","type":"journal-article","created":{"date-parts":[[2009,10,9]],"date-time":"2009-10-09T06:02:12Z","timestamp":1255068132000},"page":"45-51","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"title":["Cardiovascular event rates in patients with cerebrovascular disease and atherothrombosis at other vascular locations: Results from 1-year outcomes in the Japanese REACH Registry"],"prefix":"10.1016","volume":"287","author":[{"given":"Shinichiro","family":"Uchiyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Goto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayasu","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryozo","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Origasa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Shigematsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiro","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak L.","family":"Bhatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Gabriel","family":"Steg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2009.09.011_bib1","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1001\/jama.294.10.1255","article-title":"Trends in the leading causes of death in the United States, 1970\u20132002","volume":"294","author":"Jemal","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.jns.2009.09.011_bib2","series-title":"Abridged life tables for Japan","year":"2005"},{"key":"10.1016\/j.jns.2009.09.011_bib3","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1253\/circj.71.995","article-title":"Prevalence, awareness, and treatment of cardiovascular risk factors in patients at high risk of atherothrombosis in Japan. Results from domestic baseline data of the REduction of Atherothrombosis for Continued Health (REACH) registry","volume":"71","author":"Yamazaki","year":"2007","journal-title":"Circ J"},{"key":"10.1016\/j.jns.2009.09.011_bib4","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.ahj.2005.11.004","article-title":"The REduction of Atherothrombosis for Continued Health (REACH) Registry: an international, prospective, observational investigation in subjects at risk for atherothrombotic events\u2014study design","volume":"151","author":"Ohman","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.jns.2009.09.011_bib5","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0021-9681(82)90019-4","article-title":"Corrected group prognostic curves and summary statistics","volume":"35","author":"Chang","year":"1982","journal-title":"J Chronic Dis"},{"key":"10.1016\/j.jns.2009.09.011_bib6","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1001\/jama.297.11.1197","article-title":"One-year cardiovascular event rates in outpatients with atherothrombosis","volume":"297","author":"Steg","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.jns.2009.09.011_bib7","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1001\/jama.295.2.180","article-title":"International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis","volume":"295","author":"Bhatt","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.jns.2009.09.011_bib8","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.ahj.2008.06.029","article-title":"Prevalence, clinical profile, and cardiovascular outcomes of atrial fibrillation patients with atherothrombosis","volume":"156","author":"Goto","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.jns.2009.09.011_bib9","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1161\/01.STR.32.8.1745","article-title":"Changes in stroke mortality rates for 1950 to 1997: a great slowdown of decline trend in Japan","volume":"32","author":"Liu","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2009.09.011_bib10","series-title":"Stroke Databank","author":"Kobayashi","year":"2005"},{"key":"10.1016\/j.jns.2009.09.011_bib11","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(96)09457-3","article-title":"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)","volume":"348","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2009.09.011_bib12","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1161\/01.STR.31.9.2080","article-title":"Five-year survival after first-ever stroke and related prognostic factors in the Perth Community Stroke Study","volume":"31","author":"Hankey","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2009.09.011_bib13","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1161\/01.STR.31.4.817","volume":"31","author":"Yamaguchi","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2009.09.011_bib14","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0140-6736(04)16721-4","article-title":"Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attach in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial","volume":"364","author":"Diener","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2009.09.011_bib15","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1161\/STROKEAHA.107.504993","article-title":"Dual antithrombotic therapy increases severe bleeding events in patients with stroke and cardiovascular disease: a prospective multicenter observational study","volume":"39","author":"Toyoda","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2009.09.011_bib16","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1159\/000111498","article-title":"A randomized, double-blind study comparing the safety and efficacy of clopidogrel versus ticlopidine in Japanese patients with noncardioembolic cerebral infarction","volume":"25","author":"Fukuuchi","year":"2008","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.jns.2009.09.011_bib17","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1161\/CIRCULATIONAHA.106.653741","article-title":"Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?","volume":"115","author":"Liao","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jns.2009.09.011_bib18","doi-asserted-by":"crossref","first-page":"613","DOI":"10.2165\/00003495-200767040-00013","article-title":"Clopidogrel: a review of its use in the prevention of thrombosis","volume":"67","author":"Plosker","year":"2007","journal-title":"Drugs"},{"issue":"Suppl. 5","key":"10.1016\/j.jns.2009.09.011_bib19","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000047602","article-title":"Update on clinical trials of antiplatelet therapy for cerebrovascular diseases","volume":"10","author":"Bhatt","year":"2000","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.jns.2009.09.011_bib20","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1080\/00015458.2007.11680112","article-title":"Occurrence of peripheral arterial disease in a Belgian cohort of patients with cardiovascular history of atherothrombosis","volume":"107","author":"Missault","year":"2007","journal-title":"Acta Chir Belg"},{"key":"10.1016\/j.jns.2009.09.011_bib21","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1046\/j.1440-1622.1999.01501.x","article-title":"Prevalence of significant carotid stenosis in Chinese patients with peripheral and coronary artery disease","volume":"69","author":"Cheng","year":"1999","journal-title":"Aust N Z Surg"},{"key":"10.1016\/j.jns.2009.09.011_bib22","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1136\/bmj.313.7070.1440","article-title":"Use of ankle brachial pressure index to predict cardiovascular events and death: a cohort study","volume":"313","author":"Leng","year":"1996","journal-title":"BMJ"},{"key":"10.1016\/j.jns.2009.09.011_bib23","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1046\/j.1365-2796.2002.00947.x","article-title":"Preventing atherothrombotic events in peripheral arterial disease: the use of antiplatelet therapy","volume":"251","author":"Hiatt","year":"2002","journal-title":"J Intern Med"},{"key":"10.1016\/j.jns.2009.09.011_bib24","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.ijcard.2005.09.024","article-title":"Prognosis of patients with atherothrombotic disease: a prospective survey in a non-hospital setting","volume":"112","author":"Ferri\u00e8res","year":"2006","journal-title":"Int J Cardiol"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X09008533?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X09008533?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:40:20Z","timestamp":1758382820000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X09008533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":24,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0022510X09008533"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2009.09.011","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiovascular event rates in patients with cerebrovascular disease and atherothrombosis at other vascular locations: Results from 1-year outcomes in the Japanese REACH Registry","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2009.09.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier B.V. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}