{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:46:02Z","timestamp":1791085562265,"version":"4.1.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.jns.2011.06.056","type":"journal-article","created":{"date-parts":[[2011,7,25]],"date-time":"2011-07-25T19:11:27Z","timestamp":1311621087000},"page":"53-57","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"title":["Increased dopamine transporter density in Parkinson's disease patients with social anxiety disorder"],"prefix":"10.1016","volume":"310","author":[{"given":"Tais S.","family":"Moriyama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 C.","family":"Felicio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos H.N.","family":"Chagas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00edtor S.","family":"Tardelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Ballalai","family":"Ferraz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor","family":"Tumas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edson","family":"Amaro-Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Augusto F.","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Alexandre","family":"Crippa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo A.","family":"Bressan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"13 Suppl","key":"10.1016\/j.jns.2011.06.056_bb0005","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/j.parkreldis.2007.06.003","article-title":"The economic impact of Parkinson's disease","author":"Findley","year":"2007","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.jns.2011.06.056_bb0010","series-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2000"},{"issue":"9618","key":"10.1016\/j.jns.2011.06.056_bb0015","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0140-6736(08)60488-2","article-title":"Social anxiety disorder","volume":"371","author":"Stein","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2011.06.056_bb0020","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1034\/j.1600-0447.108.s417.2.x","article-title":"The impairments caused by social phobia in the general population: implications for intervention","volume":"417","author":"Kessler","year":"2003","journal-title":"Acta Psychiatr Scand Suppl"},{"issue":"9","key":"10.1016\/j.jns.2011.06.056_bb0025","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1002\/mds.22611","article-title":"Prevalence of anxiety disorders and anxiety subtypes in patients with Parkinson's disease","volume":"24","author":"Pontone","year":"2009","journal-title":"Mov Disord"},{"issue":"1","key":"10.1016\/j.jns.2011.06.056_bb0030","first-page":"27","article-title":"Prevalence of mental disorders in persons with Parkinson's disease","volume":"142","author":"de Rijk","year":"1998","journal-title":"Ned Tijdschr Geneeskd"},{"issue":"4","key":"10.1016\/j.jns.2011.06.056_bb0035","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1176\/jnp.2010.22.4.390","article-title":"Social anxiety in patients with Parkinson's disease","volume":"22","author":"Bolluk","year":"2010","journal-title":"J Neuropsychiatry Clin Neurosci"},{"issue":"2","key":"10.1016\/j.jns.2011.06.056_bb0040","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1176\/ajp.147.2.217","article-title":"Anxiety disorders in patients with Parkinson's disease","volume":"147","author":"Stein","year":"1990","journal-title":"Am J Psychiatry"},{"issue":"12","key":"10.1016\/j.jns.2011.06.056_bb0045","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1002\/mds.22221","article-title":"Frequency of social phobia and psychometric properties of the Liebowitz social anxiety scale in Parkinson's disease","volume":"23","author":"Kummer","year":"2008","journal-title":"Mov Disord"},{"issue":"4","key":"10.1016\/j.jns.2011.06.056_bb0050","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1590\/S1516-44462006000400003","article-title":"Dopamine and social anxiety disorder","volume":"28","author":"Robinson","year":"2006","journal-title":"Rev Bras Psiquiatr"},{"issue":"12","key":"10.1016\/j.jns.2011.06.056_bb0055","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1176\/ajp.138.12.1572","article-title":"School avoidance and social phobia triggered by haloperidol in patients with Tourette's disorder","volume":"138","author":"Mikkelsen","year":"1981","journal-title":"Am J Psychiatry"},{"issue":"12","key":"10.1016\/j.jns.2011.06.056_bb0060","doi-asserted-by":"crossref","first-page":"819","DOI":"10.4088\/JCP.v60n1203","article-title":"The emergence of social phobia during clozapine treatment and its response to fluoxetine augmentation","volume":"60","author":"Pallanti","year":"1999","journal-title":"J Clin Psychiatry"},{"issue":"3","key":"10.1016\/j.jns.2011.06.056_bb0065","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1176\/appi.ajp.157.3.457","article-title":"Low dopamine D(2) receptor binding potential in social phobia","volume":"157","author":"Schneier","year":"2000","journal-title":"Am J Psychiatry"},{"issue":"1","key":"10.1016\/j.jns.2011.06.056_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/da.20268","article-title":"Striatal dopamine D(2) receptor availability in OCD with and without comorbid social anxiety disorder: preliminary findings","volume":"25","author":"Schneier","year":"2008","journal-title":"Depress Anxiety"},{"issue":"2","key":"10.1016\/j.jns.2011.06.056_bb0075","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1176\/ajp.154.2.239","article-title":"Dopamine reuptake site densities in patients with social phobia","volume":"154","author":"Tiihonen","year":"1997","journal-title":"Am J Psychiatry"},{"issue":"5","key":"10.1016\/j.jns.2011.06.056_bb0080","doi-asserted-by":"crossref","first-page":"757","DOI":"10.2967\/jnumed.107.045518","article-title":"Increased serotonin and dopamine transporter binding in psychotropic medication-naive patients with generalized social anxiety disorder shown by 123I-beta-(4-iodophenyl)-tropane SPECT","volume":"49","author":"van der Wee","year":"2008","journal-title":"J Nucl Med"},{"issue":"3","key":"10.1016\/j.jns.2011.06.056_bb0085","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.biopsych.2006.05.043","article-title":"Striatal function in generalized social phobia: a functional magnetic resonance imaging study","volume":"61","author":"Sareen","year":"2007","journal-title":"Biol Psychiatry"},{"issue":"6","key":"10.1016\/j.jns.2011.06.056_bb0090","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0006-3223(94)91217-3","article-title":"Plasma and CSF HVA levels in panic patients with comorbid social phobia","volume":"36","author":"Johnson","year":"1994","journal-title":"Biol Psychiatry"},{"issue":"9","key":"10.1016\/j.jns.2011.06.056_bb0095","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1176\/appi.ajp.161.9.1703","article-title":"Association between catechol-O-methyltransferase and phobic anxiety","volume":"161","author":"McGrath","year":"2004","journal-title":"Am J Psychiatry"},{"issue":"4","key":"10.1016\/j.jns.2011.06.056_bb0100","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1017\/S1461145703003791","article-title":"The evidence-based pharmacological treatment of social anxiety disorder","volume":"6","author":"Blanco","year":"2003","journal-title":"Int J Neuropsychopharmacol"},{"issue":"6","key":"10.1016\/j.jns.2011.06.056_bb0105","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1002\/mds.21315","article-title":"Higher nigrostriatal dopamine neuron loss in early than late onset Parkinson's disease?\u2014a [99mTc]-TRODAT-1 SPECT study","volume":"22","author":"Shih","year":"2007","journal-title":"Mov Disord"},{"issue":"3","key":"10.1016\/j.jns.2011.06.056_bb0110","first-page":"393","article-title":"Sensitivity and specificity of 99mTc-TRODAT-1 SPECT imaging in differentiating patients with idiopathic Parkinson's disease from healthy subjects","volume":"45","author":"Weng","year":"2004","journal-title":"J Nucl Med"},{"issue":"1","key":"10.1016\/j.jns.2011.06.056_bb0115","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s00213-010-1867-y","article-title":"Higher dopamine transporter density in Parkinson's disease patients with depression","volume":"211","author":"Felicio","year":"2010","journal-title":"Psychopharmacology (Berl)"},{"issue":"6","key":"10.1016\/j.jns.2011.06.056_bb0120","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1136\/jnnp.51.6.745","article-title":"The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease","volume":"51","author":"Gibb","year":"1988","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3B","key":"10.1016\/j.jns.2011.06.056_bb0125","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1590\/S0004-282X2003000500014","article-title":"Suggestions for utilization of the mini-mental state examination in Brazil","volume":"61","author":"Brucki","year":"2003","journal-title":"Arq Neuropsiquiatr"},{"issue":"11","key":"10.1016\/j.jns.2011.06.056_bb0130","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1002\/mds.22173","article-title":"Cut-off score of the Mattis Dementia Rating Scale for screening dementia in Parkinson's disease","volume":"23","author":"Llebaria","year":"2008","journal-title":"Mov Disord"},{"key":"10.1016\/j.jns.2011.06.056_bb0135","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1590\/S1516-44462001000300008","article-title":"Confiability of the structured clinical interview for DSM-IV \u2014 clinical version translated into Portuguese","volume":"23","author":"Del-Ben","year":"2001","journal-title":"Rev Bras Psiquiatr"},{"issue":"15","key":"10.1016\/j.jns.2011.06.056_bb0140","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1002\/mds.22589","article-title":"Neuropsychiatric symptoms in Parkinson's disease","volume":"24","author":"Aarsland","year":"2009","journal-title":"Mov Disord"},{"issue":"3","key":"10.1016\/j.jns.2011.06.056_bb0145","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.eurpsy.2009.08.002","article-title":"Study of the psychometric qualities of the Brief Social Phobia Scale (BSPS) in Brazilian university students","volume":"25","author":"Osorio","year":"2010","journal-title":"Eur Psychiatry"},{"key":"10.1016\/j.jns.2011.06.056_bb0150","first-page":"220","article-title":"Utility and reliability of a simplified clinical scale for Parkinson's disease","volume":"62","author":"Tumas","year":"2004","journal-title":"Arq Neuropsiquiatr"},{"issue":"5","key":"10.1016\/j.jns.2011.06.056_bb0155","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1212\/WNL.17.5.427","article-title":"Parkinsonism: onset, progression and mortality","volume":"17","author":"Hoehn","year":"1967","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2011.06.056_bb0160","article-title":"Projection technique for evaluating surgery in Parkinson's disease","author":"Schwab","year":"1969"},{"issue":"4","key":"10.1016\/j.jns.2011.06.056_bb0165","first-page":"372","article-title":"[99mTc]TRODAT-1: a novel technetium-99m complex as a dopamine transporter imaging agent","volume":"24","author":"Kung","year":"1997","journal-title":"Eur J Nucl Med"},{"issue":"3A","key":"10.1016\/j.jns.2011.06.056_bb0170","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1590\/S0004-282X2006000400021","article-title":"Neuroimaging of the dopamine transporter in Parkinsons disease: first study using [99mTc]-TRODAT-1 and SPECT in Brazil","volume":"64","author":"Shih","year":"2006","journal-title":"Arq Neuropsiquiatr"},{"issue":"5","key":"10.1016\/j.jns.2011.06.056_bb0175","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/da.20543","article-title":"Dopamine transporters, D2 receptors, and dopamine release in generalized social anxiety disorder","volume":"26","author":"Schneier","year":"2009","journal-title":"Depress Anxiety"},{"issue":"1","key":"10.1016\/j.jns.2011.06.056_bb0180","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/(SICI)1098-2396(199805)29:1<80::AID-SYN7>3.0.CO;2-7","article-title":"Effect of social status on striatal dopamine D2 receptor binding characteristics in cynomolgus monkeys assessed with positron emission tomography","volume":"29","author":"Grant","year":"1998","journal-title":"Synapse"},{"issue":"3","key":"10.1016\/j.jns.2011.06.056_bb0185","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.biopsych.2009.07.037","article-title":"Dopamine type 2\/3 receptor availability in the striatum and social status in human volunteers","volume":"67","author":"Martinez","year":"2010","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.jns.2011.06.056_bb0190","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1177\/026988110201600412","article-title":"Efficacy of olanzapine in social anxiety disorder: a pilot study","volume":"16","author":"Barnett","year":"2002","journal-title":"J Psychopharmacol"},{"issue":"11","key":"10.1016\/j.jns.2011.06.056_bb0195","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1001\/archpsyc.1996.01830110060007","article-title":"Lifetime prevalence, demographic risk factors, and diagnostic validity of nonaffective psychosis as assessed in a US community sample. The National Comorbidity Survey","volume":"53","author":"Kendler","year":"1996","journal-title":"Arch Gen Psychiatry"},{"issue":"1","key":"10.1016\/j.jns.2011.06.056_bb0200","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/NRL.0b013e318183fdd8","article-title":"Molecular imaging studies in Parkinson disease: reducing diagnostic uncertainty","volume":"15","author":"Felicio","year":"2009","journal-title":"Neurologist"},{"issue":"3","key":"10.1016\/j.jns.2011.06.056_bb0205","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1177\/089198879901200306","article-title":"Pathophysiology of secondary depressions in the elderly","volume":"12","author":"Robinson","year":"1999","journal-title":"J Geriatr Psychiatry Neurol"},{"issue":"2","key":"10.1016\/j.jns.2011.06.056_bb0210","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.neuroimage.2009.04.059","article-title":"Depression in Parkinson's disease: convergence from voxel-based morphometry and functional magnetic resonance imaging in the limbic thalamus","volume":"47","author":"Cardoso","year":"2009","journal-title":"Neuroimage"},{"issue":"2","key":"10.1016\/j.jns.2011.06.056_bb0215","first-page":"227","article-title":"Striatal dopamine transporter imaging correlates with anxiety and depression symptoms in Parkinson's disease","volume":"46","author":"Weintraub","year":"2005","journal-title":"J Nucl Med"},{"issue":"4","key":"10.1016\/j.jns.2011.06.056_bb0220","first-page":"201","article-title":"The ups and downs of Parkinson disease: a prospective study of mood and anxiety fluctuations","volume":"17","author":"Richard","year":"2004","journal-title":"Cogn Behav Neurol"},{"issue":"7","key":"10.1016\/j.jns.2011.06.056_bb0225","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/0006-3223(93)90237-8","article-title":"Parkinson's disease and anxiety: comorbidity with depression","volume":"34","author":"Menza","year":"1993","journal-title":"Biol Psychiatry"},{"issue":"3","key":"10.1016\/j.jns.2011.06.056_bb0230","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1017\/S0033291700022261","article-title":"Left-sided Parkinson's disease is associated with greater anxiety and depression","volume":"21","author":"Fleminger","year":"1991","journal-title":"Psychol Med"},{"issue":"1","key":"10.1016\/j.jns.2011.06.056_bb0235","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0924-9338(00)00209-1","article-title":"Are social fears and DSM-IV social anxiety disorder associated with smoking and nicotine dependence in adolescents and young adults?","volume":"15","author":"Sonntag","year":"2000","journal-title":"Eur Psychiatry"},{"issue":"1","key":"10.1016\/j.jns.2011.06.056_bb0240","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0920-9964(02)00500-5","article-title":"Nicotinic receptor-mediated regulation of the dopamine transporter in rat prefrontocortical slices following chronic in vivo administration of nicotine","volume":"65","author":"Drew","year":"2003","journal-title":"Schizophr Res"},{"key":"10.1016\/j.jns.2011.06.056_bb0245","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/978-3-540-69248-5_6","article-title":"In vivo brain imaging of human exposure to nicotine and tobacco","volume":"192","author":"Sharma","year":"2009","journal-title":"Handb Exp Pharmacol"},{"issue":"9","key":"10.1016\/j.jns.2011.06.056_bb0250","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1002\/mds.22032","article-title":"Genetic and environmental findings in early-onset Parkinson's disease Brazilian patients","volume":"23","author":"Aguiar Pde","year":"2008","journal-title":"Mov Disord"},{"issue":"5","key":"10.1016\/j.jns.2011.06.056_bb0255","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1002\/ana.21204","article-title":"Dopamine transporter relation to dopamine turnover in Parkinson's disease: a positron emission tomography study","volume":"62","author":"Sossi","year":"2007","journal-title":"Ann Neurol"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X11003911?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X11003911?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:42:20Z","timestamp":1758382940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X11003911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":51,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0022510X11003911"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2011.06.056","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased dopamine transporter density in Parkinson's disease patients with social anxiety disorder","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2011.06.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}