{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T15:48:25Z","timestamp":1787154505135,"version":"build-2736575974"},"reference-count":31,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.jns.2011.12.014","type":"journal-article","created":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T10:45:13Z","timestamp":1326710713000},"page":"133-136","source":"Crossref","is-referenced-by-count":32,"title":["NGF and nitrosative stress in patients with Huntington's disease"],"prefix":"10.1016","volume":"315","author":[{"given":"Inmaculada","family":"Tasset","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"S\u00e1nchez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Ag\u00fcera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Fern\u00e1ndez-Bola\u00f1os","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Manuel","family":"S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Cruz-Guerrero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Gasc\u00f3n-Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"T\u00fanez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jns.2011.12.014_bb0165","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/08977190410001723308","article-title":"Brain-derived neurotrophic factor","volume":"22","author":"Binder","year":"2004","journal-title":"Growth Factors"},{"issue":"5\u20136","key":"10.1016\/j.jns.2011.12.014_bb0015","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.pneurobio.2007.01.003","article-title":"Role of brain-derived neurotrophic factor in Huntington's disease","volume":"81","author":"Zuccato","year":"2007","journal-title":"Prog Neurobiol"},{"issue":"2","key":"10.1016\/j.jns.2011.12.014_bb0020","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1750-3639.2007.00111.x","article-title":"Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease","volume":"18","author":"Zuccato","year":"2008","journal-title":"Brain Pathol"},{"issue":"4","key":"10.1016\/j.jns.2011.12.014_bb0170","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000319946","article-title":"Associations between brain-derived neurotrophic factor plasma levels and severity of the illness, recurrence and symptoms in depressed patients","volume":"62","author":"Dell'Osso","year":"2010","journal-title":"Neuropsychobiology"},{"issue":"5","key":"10.1016\/j.jns.2011.12.014_bb0175","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1080\/07420520802387773","article-title":"Diurnal variation of plasma brain-derived neurotrophic factor (BDNF) in humans: an analysis of sex differences","volume":"25","author":"Piccinni","year":"2008","journal-title":"Chronobiol Int"},{"issue":"1","key":"10.1016\/j.jns.2011.12.014_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mcn.2008.04.012","article-title":"Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347","volume":"39","author":"Conforti","year":"2008","journal-title":"Mol Cell Neurosci"},{"issue":"2","key":"10.1016\/j.jns.2011.12.014_bb0180","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/mds.870110204","article-title":"Unified Huntington's Disease Rating Scale: reliability and consistency. Huntington Study Group","volume":"11","year":"1996","journal-title":"Mov Disord"},{"issue":"3","key":"10.1016\/j.jns.2011.12.014_bb0045","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"issue":"153","key":"10.1016\/j.jns.2011.12.014_bb0050","first-page":"744","article-title":"Nerve growth factor and neurological diseases","volume":"26","author":"Lorigados","year":"1998","journal-title":"Rev Neurol"},{"issue":"4","key":"10.1016\/j.jns.2011.12.014_bb0055","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1023\/A:1016990503061","article-title":"Presence of nerve growth factor in the thymus of prenatal, postnatal and pregnant rats","volume":"24","author":"Aloe","year":"1997","journal-title":"Thymus"},{"issue":"4","key":"10.1016\/j.jns.2011.12.014_bb0060","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/ajmg.b.30501","article-title":"Low brain-derived neurotrophic factor (BDNF) levels in serum of Huntington's disease patients","volume":"144B","author":"Ciammola","year":"2007","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"4","key":"10.1016\/j.jns.2011.12.014_bb0065","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1007\/s00415-009-5357-2","article-title":"Serum levels of brain-derived neurotrophic factor correlate with motor impairment in Parkinson's disease","volume":"257","author":"Scalzo","year":"2010","journal-title":"J Neurol"},{"issue":"3","key":"10.1016\/j.jns.2011.12.014_bb0070","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s10072-009-0209-5","article-title":"Serum levels of brain-derived neurotrophic factor in Sydenham's chorea","volume":"31","author":"Teixeira","year":"2010","journal-title":"Neurol Sci"},{"issue":"4","key":"10.1016\/j.jns.2011.12.014_bb0075","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0891-0618(01)00115-6","article-title":"Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain","volume":"21","author":"Chauhan","year":"2001","journal-title":"J Chem Neuroanat"},{"issue":"18","key":"10.1016\/j.jns.2011.12.014_bb0080","doi-asserted-by":"crossref","first-page":"6236","DOI":"10.1523\/JNEUROSCI.0567-10.2010","article-title":"Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors","volume":"30","author":"Ubhi","year":"2010","journal-title":"J Neurosci"},{"issue":"2","key":"10.1016\/j.jns.2011.12.014_bb0085","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/ana.410310202","article-title":"Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?","volume":"31","author":"Beal","year":"1992","journal-title":"Ann Neurol"},{"issue":"1","key":"10.1016\/j.jns.2011.12.014_bb0090","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/1531-8249(199901)45:1<25::AID-ART6>3.0.CO;2-E","article-title":"Biochemical abnormalities and excitotoxicity in Huntington's disease brain","volume":"45","author":"Tabrizi","year":"1999","journal-title":"Ann Neurol"},{"issue":"12","key":"10.1016\/j.jns.2011.12.014_bb0095","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1007\/s00415-007-0611-y","article-title":"Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects: a cross-sectional study","volume":"254","author":"Klepac","year":"2007","journal-title":"J Neurol"},{"issue":"5","key":"10.1016\/j.jns.2011.12.014_bb0100","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.freeradbiomed.2008.05.014","article-title":"Proteomic and oxidative stress analysis in human brain samples of Huntington disease","volume":"45","author":"Sorolla","year":"2008","journal-title":"Free Radic Biol Med"},{"issue":"1","key":"10.1016\/j.jns.2011.12.014_bb0105","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1523\/JNEUROSCI.18-01-00156.1998","article-title":"Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease","volume":"18","author":"Matthews","year":"1998","journal-title":"J Neurosci"},{"issue":"5","key":"10.1016\/j.jns.2011.12.014_bb0110","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.neuint.2005.11.011","article-title":"17 beta-Estradiol may affect vulnerability of striatum in a 3-nitropropionic acid-induced experimental model of Huntington's disease in ovariectomized rats","volume":"48","author":"Tunez","year":"2006","journal-title":"Neurochem Int"},{"issue":"3","key":"10.1016\/j.jns.2011.12.014_bb0115","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1089\/jmf.2008.0028","article-title":"Possible neuroprotective effect of Withania somnifera root extract against 3-nitropropionic acid-induced behavioral, biochemical, and mitochondrial dysfunction in an animal model of Huntington's disease","volume":"12","author":"Kumar","year":"2009","journal-title":"J Med Food"},{"issue":"4","key":"10.1016\/j.jns.2011.12.014_bb0120","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.biopha.2009.06.020","article-title":"Neuroprotective effects of l-carnitine in a transgenic animal model of Huntington's disease","volume":"64","author":"Vamos","year":"2010","journal-title":"Biomed Pharmacother"},{"issue":"15\u201317","key":"10.1016\/j.jns.2011.12.014_bb0125","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1097\/00001756-199611040-00046","article-title":"NGF attenuates 3-nitrotyrosine formation in a 3-NP model of Huntington's disease","volume":"7","author":"Galpern","year":"1996","journal-title":"Neuroreport"},{"issue":"2","key":"10.1016\/j.jns.2011.12.014_bb0130","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2298\/VSP0202119M","article-title":"Effects of nerve and fibroblast growth factors on the production of nitric oxide in experimental model of Huntington's disease","volume":"59","author":"Maksimovic","year":"2002","journal-title":"Vojnosanit Pregl"},{"issue":"1","key":"10.1016\/j.jns.2011.12.014_bb0135","first-page":"573","article-title":"Synergistic protective effect of picroside II and NGF on PC12 cells against oxidative stress induced by H2O2","volume":"59","author":"Cao","year":"2007","journal-title":"Pharmacol Rep"},{"issue":"2\u20133","key":"10.1016\/j.jns.2011.12.014_bb0140","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s12035-009-8097-5","article-title":"Targeting glial cells to elucidate the pathogenesis of Huntington's disease","volume":"41","author":"Hsiao","year":"2010","journal-title":"Mol Neurobiol"},{"issue":"4","key":"10.1016\/j.jns.2011.12.014_bb0145","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1159\/000200022","article-title":"Infliximab reduces myeloperoxidase concentration in chronic inflammatory joint diseases","volume":"83","author":"Feijoo","year":"2009","journal-title":"Pharmacology"},{"issue":"7","key":"10.1016\/j.jns.2011.12.014_bb0150","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1021\/pr0700753","article-title":"Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates","volume":"6","author":"Dalrymple","year":"2007","journal-title":"J Proteome Res"},{"issue":"8","key":"10.1016\/j.jns.2011.12.014_bb0155","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1084\/jem.20080178","article-title":"A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease","volume":"205","author":"Bjorkqvist","year":"2008","journal-title":"J Exp Med"},{"issue":"2","key":"10.1016\/j.jns.2011.12.014_bb0160","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/path.2749","article-title":"Glial-derived neurotrophic factor regulates intestinal epithelial barrier function and inflammation and is therapeutic for murine colitis","volume":"222","author":"Zhang","year":"2010","journal-title":"J Pathol"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X11007519?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X11007519?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,22]],"date-time":"2019-06-22T14:33:18Z","timestamp":1561213998000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X11007519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":31,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0022510X11007519"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2011.12.014","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}