{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:05:56Z","timestamp":1789949156904,"version":"4.0.1"},"reference-count":68,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.jns.2012.05.046","type":"journal-article","created":{"date-parts":[[2012,6,13]],"date-time":"2012-06-13T11:46:44Z","timestamp":1339588004000},"page":"237-240","source":"Crossref","is-referenced-by-count":33,"title":["Pre-clinical models of human cerebral small vessel disease: Utility for clinical application"],"prefix":"10.1016","volume":"322","author":[{"given":"Atticus H.","family":"Hainsworth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Brittain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halima","family":"Khatun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2012.05.046_bb0005","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1161\/01.STR.22.8.993","article-title":"An autopsy study of the incidence of lacunes in relation to age, hypertension, and arteriosclerosis","volume":"22","author":"Dozono","year":"1991","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00685305","article-title":"The arterial lesions underlying lacunes","volume":"12","author":"Fisher","year":"1968","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.jns.2012.05.046_bb0015","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1002\/gps.1144","article-title":"Association between subcortical vascular disease on CT and neuropathological findings","volume":"19","author":"Rossi","year":"2004","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.jns.2012.05.046_bb0020","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1161\/01.STR.0000221308.94473.14","article-title":"White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury","volume":"37","author":"Fernando","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0025","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00401-011-0851-x","article-title":"Heterogeneity in age-related white matter changes","volume":"122","author":"Schmidt","year":"2011","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.jns.2012.05.046_bb0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.neures.2011.07.1820","article-title":"Subcortical vascular dementia","volume":"71","author":"Tomimoto","year":"2011","journal-title":"Neurosci Res"},{"key":"10.1016\/j.jns.2012.05.046_bb0035","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1136\/jnnp.63.6.749","article-title":"Neuropathological assessment of the lesions of significance in vascular dementia","volume":"63","author":"Esiri","year":"1997","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jns.2012.05.046_bb0040","series-title":"Vascular Cognitive Impairment in Clinical Practice","first-page":"118","article-title":"Small-vessel diseases of the brain","author":"Kalaria","year":"2009"},{"key":"10.1016\/j.jns.2012.05.046_bb0045","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S1474-4422(03)00305-3","article-title":"Vascular cognitive impairment","volume":"2","author":"O'Brien","year":"2003","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jns.2012.05.046_bb0050","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0140-6736(00)03589-3","article-title":"Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)","volume":"357","author":"MRC-CFAS","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2012.05.046_bb0055","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1056\/NEJMoa0806142","article-title":"Age, neuropathology, and dementia","volume":"360","author":"Savva","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jns.2012.05.046_bb0060","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1038\/jcbfm.2008.91","article-title":"Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review","volume":"28","author":"Hainsworth","year":"2008","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jns.2012.05.046_bb0065","doi-asserted-by":"crossref","first-page":"e451","DOI":"10.1161\/STROKEAHA.108.528430","article-title":"Potential animal models of lacunar stroke: a systematic review","volume":"40","author":"Bailey","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0070","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1365-2990.2011.01170.x","article-title":"Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats","volume":"37","author":"Bailey","year":"2011","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.jns.2012.05.046_bb0075","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1111\/j.1471-4159.2010.06958.x","article-title":"Experimental models of vascular dementia and vascular cognitive impairment. A systematic review","volume":"115","author":"Jiwa","year":"2010","journal-title":"J Neurochem"},{"key":"10.1016\/j.jns.2012.05.046_bb0080","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1172\/JCI39733","article-title":"Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease","volume":"120","author":"Joutel","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jns.2012.05.046_bb0085","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1016\/j.jalz.2007.01.002","article-title":"Cerebrovascular disease and dementia: a primate model of hypertension and cognition","volume":"3","author":"Moss","year":"2007","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jns.2012.05.046_bb0090","doi-asserted-by":"crossref","first-page":"5621","DOI":"10.1073\/pnas.090504197","article-title":"A universal scaling law between gray matter and white matter of cerebral cortex","volume":"97","author":"Zhang","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jns.2012.05.046_bb0095","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1111\/j.1365-2990.2011.01246.x","article-title":"Cerebral Abeta(42) deposits and microvascular pathology in ageing baboons","volume":"38","author":"Ndung'u","year":"2012","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.jns.2012.05.046_bb0100","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.neuroscience.2010.03.003","article-title":"Effects of aerobic exercise training on cognitive function and cortical vascularity in monkeys","volume":"167","author":"Rhyu","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.jns.2012.05.046_bb0105","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s004010051083","article-title":"Microinfarction as a result of hypertension in a primate model of cerebrovascular disease","volume":"98","author":"Kemper","year":"1999","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.jns.2012.05.046_bb0110","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s004010000278","article-title":"Neuropathology of progressive cognitive decline in chronically hypertensive rhesus monkeys","volume":"101","author":"Kemper","year":"2001","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.jns.2012.05.046_bb0115","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1212\/WNL.15.8.774","article-title":"Lacunes: small, deep cerebral infarcts","volume":"15","author":"Fisher","year":"1965","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2012.05.046_bb0120","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0022-510X(02)00302-7","article-title":"Cognitive impairment and chronic cerebral hypoperfusion: what can be learned from experimental models","volume":"203\u2013204","author":"Sarti","year":"2002","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.jns.2012.05.046_bb0125","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1161\/01.STR.7.1.46","article-title":"Pathogenetic similarity of strokes in stroke-prone spontaneously hypertensive rats and humans","volume":"7","author":"Yamori","year":"1976","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0130","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/01.STR.8.4.456","article-title":"Developmental course of hypertension and regional cerebral blood flow in stroke-prone spontaneously hypertensive rats","volume":"8","author":"Yamori","year":"1977","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0135","first-page":"464","article-title":"Composition and mechanics of cerebral arterioles in hypertensive rats","volume":"133","author":"Baumbach","year":"1988","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jns.2012.05.046_bb0140","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1161\/01.STR.16.2.313","article-title":"The morphometry of consecutive segments in cerebral arteries of normotensive and spontaneously hypertensive rats","volume":"16","author":"Nordborg","year":"1985","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0145","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1161\/01.STR.18.4.733","article-title":"Ultrastructural characteristics of occluded perforating arteries in stroke-prone spontaneously hypertensive rats","volume":"18","author":"Tagami","year":"1987","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0150","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1097\/00001756-200107030-00015","article-title":"White matter lesions and alteration of vascular cell composition in the brain of spontaneously hypertensive rats","volume":"12","author":"Lin","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.jns.2012.05.046_bb0155","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.neulet.2003.09.079","article-title":"Stroke-prone rats exhibit prolonged behavioral deficits without increased brain injury: an indication of disrupted post-stroke brain recovery of function","volume":"354","author":"Maguire","year":"2004","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jns.2012.05.046_bb0160","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/jcbfm.2011.122","article-title":"The pathologic cascade of cerebrovascular lesions in SHRSP: is erythrocyte accumulation an early phase?","volume":"32","author":"Schreiber","year":"2012","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jns.2012.05.046_bb0165","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1161\/STROKEAHA.107.491621","article-title":"Vascular permeability precedes spontaneous intracerebral hemorrhage in stroke-prone spontaneously hypertensive rats","volume":"38","author":"Lee","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0170","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/S0306-4522(97)00037-7","article-title":"Chronic cerebral hypoperfusion by permanent internal carotid ligation produces learning impairment without brain damage in rats","volume":"79","author":"Ohta","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.jns.2012.05.046_bb0175","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1161\/STROKEAHA.107.490151","article-title":"Selective impairment of working memory in a mouse model of chronic cerebral hypoperfusion","volume":"38","author":"Shibata","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0180","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1161\/STROKEAHA.110.581686","article-title":"A mouse model characterizing features of vascular dementia with hippocampal atrophy","volume":"41","author":"Nishio","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0185","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.expneurol.2007.12.005","article-title":"Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice","volume":"210","author":"Yoshizaki","year":"2008","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jns.2012.05.046_bb0190","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.neurobiolaging.2011.10.033","article-title":"Selective white matter abnormalities in a novel rat model of vascular dementia 3","volume":"33","author":"Kitamura","year":"2012","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jns.2012.05.046_bb0195","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S1474-4422(09)70127-9","article-title":"Cadasil","volume":"8","author":"Chabriat","year":"2009","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jns.2012.05.046_bb0200","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/bies.201000093","article-title":"Pathogenesis of CADASIL: transgenic and knock-out mice to probe function and dysfunction of the mutated gene, Notch3, in the cerebrovasculature","volume":"33","author":"Joutel","year":"2011","journal-title":"Bioessays"},{"key":"10.1016\/j.jns.2012.05.046_bb0205","doi-asserted-by":"crossref","first-page":"S129","DOI":"10.1161\/STROKEAHA.110.595207","article-title":"CADASIL: experimental insights from animal models 15","volume":"41","author":"Ayata","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0210","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1747-4949.2011.00659.x","article-title":"Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review","volume":"6","author":"Bailey","year":"2011","journal-title":"Int J Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0215","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1161\/01.STR.28.11.2222","article-title":"Nonhypertensive cerebral small-vessel disease. An autopsy study","volume":"28","author":"Lammie","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0220","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1258\/0007142001903229","article-title":"Pathology of small vessel stroke","volume":"56","author":"Lammie","year":"2000","journal-title":"Br Med Bull"},{"key":"10.1016\/j.jns.2012.05.046_bb0225","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S1474-4422(10)70104-6","article-title":"Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges","volume":"9","author":"Pantoni","year":"2010","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jns.2012.05.046_bb0230","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1212\/WNL.0b013e3182407968","article-title":"Neuropathologic evidence of endothelial changes in cerebral small vessel disease","volume":"78","author":"Giwa","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2012.05.046_bb0235","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1161\/01.STR.0000237236.88823.47","article-title":"National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards","volume":"37","author":"Hachinski","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0240","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.mad.2005.09.026","article-title":"Animal models of cognitive dysfunction","volume":"127","author":"Tayebati","year":"2006","journal-title":"Mech Ageing Dev"},{"key":"10.1016\/j.jns.2012.05.046_bb0245","doi-asserted-by":"crossref","first-page":"7036","DOI":"10.1073\/pnas.1000645107","article-title":"Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes","volume":"107","author":"Takeda","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jns.2012.05.046_bb0250","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0197-4580(00)00225-6","article-title":"Calcium antagonists decrease capillary wall damage in aging hypertensive rat brain","volume":"22","author":"Farkas","year":"2001","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jns.2012.05.046_bb0255","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.brainres.2008.01.103","article-title":"Cilostazol alleviates cerebral small-vessel pathology and white-matter lesions in stroke-prone spontaneously hypertensive rats","volume":"1203","author":"Fujita","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.jns.2012.05.046_bb0260","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1161\/01.HYP.2.4.419","article-title":"Effect of chronic hypertension and sympathetic denervation on wall\/lumen ratio of cerebral vessels","volume":"2","author":"Hart","year":"1980","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2012.05.046_bb0265","doi-asserted-by":"crossref","first-page":"e5159","DOI":"10.1371\/journal.pone.0005159","article-title":"Beneficial effects of estrogen in a mouse model of cerebrovascular insufficiency","volume":"4","author":"Kitamura","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.jns.2012.05.046_bb0270","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/jcbfm.2009.246","article-title":"Hypertension-induced vascular remodeling contributes to reduced cerebral perfusion and the development of spontaneous stroke in aged SHRSP rats","volume":"30","author":"Henning","year":"2010","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jns.2012.05.046_bb0275","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1016\/j.neurobiolaging.2010.11.009","article-title":"MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice 3","volume":"32","author":"Holland","year":"2011","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jns.2012.05.046_bb0280","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1161\/STROKEAHA.111.643080","article-title":"Myelin Loss Associated With Neuroinflammation in Hypertensive Rats","volume":"43","author":"Jalal","year":"2012","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0285","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1354\/vp.36-3-202","article-title":"Age-related changes in the brain of the dog","volume":"36","author":"Borras","year":"1999","journal-title":"Vet Pathol"},{"key":"10.1016\/j.jns.2012.05.046_bb0290","doi-asserted-by":"crossref","first-page":"e1000412","DOI":"10.1371\/journal.pbio.1000412","article-title":"Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research","volume":"8","author":"Kilkenny","year":"2010","journal-title":"PLoS Biol"},{"key":"10.1016\/j.jns.2012.05.046_bb0295","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1161\/STROKEAHA.107.492934","article-title":"Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats","volume":"39","author":"Lecrux","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2012.05.046_bb0300","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1161\/HYPERTENSIONAHA.107.099374","article-title":"Amelioration of cognitive impairment in the type-2 diabetic mouse by the angiotensin II type-1 receptor blocker candesartan","volume":"50","author":"Tsukuda","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2012.05.046_bb0305","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1161\/HYPERTENSIONAHA.111.173534","article-title":"Attenuation of brain damage and cognitive impairment by direct renin inhibition in mice with chronic cerebral hypoperfusion 3","volume":"58","author":"Dong","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2012.05.046_bb0310","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.nbd.2011.02.007","article-title":"Differential impact of diabetes and hypertension in the brain: adverse effects in white matter 2","volume":"42","author":"Yang","year":"2011","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.jns.2012.05.046_bb0315","doi-asserted-by":"crossref","first-page":"E128","DOI":"10.1073\/pnas.1101964108","article-title":"Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease 8","volume":"108","author":"Arboleda-Velasquez","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jns.2012.05.046_bb0320","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0197-4580(97)00155-3","article-title":"Age-induced white matter changes in the human brain: a stereological investigation","volume":"18","author":"Tang","year":"1997","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jns.2012.05.046_bb0325","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/0361-9230(81)90007-1","article-title":"Cortical blood vessels of the human brain","volume":"7","author":"Duvernoy","year":"1981","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.jns.2012.05.046_bb0330","doi-asserted-by":"crossref","first-page":"458","DOI":"10.3171\/jns.1984.61.3.0458","article-title":"Microsurgical anatomy of the proximal segments of the middle cerebral artery","volume":"61","author":"Umansky","year":"1984","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jns.2012.05.046_bb0335","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3171\/jns.1985.62.2.0261","article-title":"The perforating branches of the middle cerebral artery. A microanatomical study","volume":"62","author":"Umansky","year":"1985","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jns.2012.05.046_bb0340","doi-asserted-by":"crossref","first-page":"3164","DOI":"10.1161\/01.CIR.96.9.3164","article-title":"Long-term ACE inhibition doubles lifespan of hypertensive rats","volume":"96","author":"Linz","year":"1997","journal-title":"Circulation"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X12002754?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X12002754?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T01:53:41Z","timestamp":1594259621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X12002754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":68,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0022510X12002754"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2012.05.046","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}