{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:47:08Z","timestamp":1790614028562,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Neurological Institute C. Besta IRCCS Foundation"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.jns.2014.11.004","type":"journal-article","created":{"date-parts":[[2014,11,8]],"date-time":"2014-11-08T11:07:17Z","timestamp":1415444837000},"page":"60-66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Chronic migraine with medication overuse: Association between disability and quality of life measures, and impact of disease on patients' lives"],"prefix":"10.1016","volume":"348","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7433-7779","authenticated-orcid":false,"given":"Alberto","family":"Raggi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Schiavolin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Leonardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambra Mara","family":"Giovannetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennaro","family":"Bussone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella","family":"Curone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Di Fiore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Licia","family":"Grazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Usai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"D'Amico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2014.11.004_bb0005","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s11910-010-0175-6","article-title":"Migraine chronification","volume":"11","author":"Bigal","year":"2011","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.jns.2014.11.004_bb0010","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s11916-010-0157-z","article-title":"Chronic migraine: epidemiology and disease burden","volume":"15","author":"Manack","year":"2011","journal-title":"Curr Pain Headache Rep"},{"key":"10.1016\/j.jns.2014.11.004_bb0015","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1468-2982.2009.01941.x","article-title":"Global prevalence of chronic migraine: a systematic review","volume":"30","author":"Natoli","year":"2010","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0020","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1212\/WNL.0b013e3181974b19","article-title":"Tracing transformation: chronic migraine classification, progression, and epidemiology","volume":"72","author":"Lipton","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2014.11.004_bb0025","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1212\/01.WNL.0000113747.18760.D2","article-title":"Incidence and predictors for chronicity of headache in patients with episodic migraine","volume":"62","author":"Katsarava","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2014.11.004_bb0030","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/j.1526-4610.2008.01217.x","article-title":"Acute migraine medications and evolution from episodic to chronic migraine: a longitudinal population-based study","volume":"48","author":"Bigal","year":"2008","journal-title":"Headache"},{"key":"10.1016\/j.jns.2014.11.004_bb0035","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1177\/0333102413480755","article-title":"The role of tyrosine metabolism in the pathogenesis of chronic migraine","volume":"33","author":"D'Andrea","year":"2013","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0040","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1212\/01.WNL.0000123262.96132.FC","article-title":"Analgesic overuse among subjects with headache, neck, and low-back pain","volume":"62","author":"Zwart","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2014.11.004_bb0045","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1212\/WNL.59.7.1011","article-title":"Features of medication overuse headache following overuse of different acute headache drugs","volume":"59","author":"Limmroth","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2014.11.004_bb0050","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S1474-4422(10)70008-9","article-title":"Clinical features, pathophysiology, and treatment of medication-overuse headache","volume":"9","author":"Evers","year":"2010","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jns.2014.11.004_bb0055","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1111\/j.1468-1331.2012.03681.x","article-title":"Self-medication of regular headache: a community pharmacy-based survey","volume":"19","author":"Mehuys","year":"2012","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.jns.2014.11.004_bb0060","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s11916-009-0048-3","article-title":"Overuse of acute migraine medications and migraine chronification","volume":"13","author":"Bigal","year":"2009","journal-title":"Curr Pain Headache Rep"},{"key":"10.1016\/j.jns.2014.11.004_bb0065","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/NRL.0b013e31822d109c","article-title":"Risk of development of medication overuse headache with nonsteroidal anti-inflammatory drug therapy for migraine: a critically appraised topic","volume":"17","author":"Starling","year":"2011","journal-title":"Neurologist"},{"key":"10.1016\/j.jns.2014.11.004_bb0070","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1177\/0333102411398400","article-title":"Quality of life impairment, disability and economic burden associated with chronic daily headache, focusing on chronic migraine with or without medication overuse: a systematic review","volume":"31","author":"Lant\u00e9ri-Minet","year":"2011","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0075","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1007\/s10072-011-0552-1","article-title":"Disability in chronic daily headache: state of the art and future directions","volume":"32","author":"D'Amico","year":"2011","journal-title":"Neurol Sci"},{"key":"10.1016\/j.jns.2014.11.004_bb0080","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1468-1331.2011.03612.x","article-title":"The cost of headache disorders in Europe: the Eurolight project","volume":"19","author":"Linde","year":"2012","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.jns.2014.11.004_bb0085","doi-asserted-by":"crossref","first-page":"S169","DOI":"10.1007\/s10072-012-1076-z","article-title":"Disability and mood state in patients with episodic and chronic migraine associated to medication overuse","volume":"33","author":"Raggi","year":"2012","journal-title":"Neurol Sci"},{"key":"10.1016\/j.jns.2014.11.004_bb0090","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/j.1468-2982.2009.01932.x","article-title":"Disability in chronic migraine with medication overuse: treatment effects through 5years","volume":"30","author":"Andrasik","year":"2010","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0095","doi-asserted-by":"crossref","first-page":"S139","DOI":"10.1007\/s10072-013-1371-3","article-title":"A 14-month study of change in disability and mood state in patients with chronic migraine associated to medication overuse","volume":"34","author":"Raggi","year":"2013","journal-title":"Neurol Sci"},{"key":"10.1016\/j.jns.2014.11.004_bb0100","doi-asserted-by":"crossref","first-page":"S175","DOI":"10.1007\/s10072-013-1376-y","article-title":"Outcome of patients with chronic migraine with medication overuse and depression after duloxetine: influence of coexisting obsessive compulsive disorder","volume":"34","author":"Curone","year":"2013","journal-title":"Neurol Sci"},{"key":"10.1016\/j.jns.2014.11.004_bb0105","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1177\/0333102413515338","article-title":"Disability, anxiety and depression associated with medication-overuse headache can be considerably reduced by detoxification and prophylactic treatment. Results from a multicentre, multinational study (COMOESTAS project)","volume":"34","author":"Bendtsen","year":"2014","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0110","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1212\/WNL.53.5.988","article-title":"An international study to assess reliability of the Migraine Disability Assessment (MIDAS) score","volume":"53","author":"Stewart","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2014.11.004_bb0115","doi-asserted-by":"crossref","first-page":"S177","DOI":"10.1007\/s10072-011-0527-2","article-title":"Psychopathological profile of patients with chronic migraine and medication overuse: study and findings in 50 cases","volume":"32","author":"Curone","year":"2011","journal-title":"Neurol Sci"},{"key":"10.1016\/j.jns.2014.11.004_bb0120","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s10194-010-0208-1","article-title":"West Migraine Study Group Psychopathology and quality of life burden in chronic daily headache: influence of migraine symptoms","volume":"11","author":"Autret","year":"2010","journal-title":"J Headache Pain"},{"key":"10.1016\/j.jns.2014.11.004_bb0125","series-title":"The International Classification of Functioning, Disability and Health-ICF","author":"World Health Organization","year":"2001"},{"key":"10.1016\/j.jns.2014.11.004_bb0130","doi-asserted-by":"crossref","first-page":"815","DOI":"10.2471\/BLT.09.067231","article-title":"Developing the World Health Organization Disability Assessment Schedule 2.0","volume":"88","author":"Ustun","year":"2010","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.jns.2014.11.004_bb0135","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1111\/j.1526-4610.2010.01770.x","article-title":"Health-related quality of life, disability and severity of disease in patients with migraine attending to a specialty headache center","volume":"50","author":"Leonardi","year":"2010","journal-title":"Headache"},{"key":"10.1016\/j.jns.2014.11.004_bb0140","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s00415-009-5279-z","article-title":"The relationship between health, disability and quality of life in Myasthenia gravis: results from an Italian study","volume":"257","author":"Leonardi","year":"2010","journal-title":"J Neurol"},{"key":"10.1016\/j.jns.2014.11.004_bb0145","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1097\/PHM.0b013e31823d4db9","article-title":"The relationship between health-related quality of life and disability in patients with controlled epilepsy: a cross-sectional observational study","volume":"91","author":"Quintas","year":"2012","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.jns.2014.11.004_bb0150","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1097\/PHM.0b013e31823d4df7","article-title":"Quality of life and disability in patients with Stroke","volume":"91","author":"Cerniauskaite","year":"2012","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.jns.2014.11.004_bb0155","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.parkreldis.2011.08.011","article-title":"Relationships between disability, quality of life and prevalence of nonmotor symptoms in Parkinson's disease","volume":"18","author":"Leonardi","year":"2012","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.jns.2014.11.004_bb0160","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1212\/WNL.47.4.871","article-title":"Classification of daily and near-daily headaches","volume":"47","author":"Silberstein","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2014.11.004_bb0165","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1526-4610.2000.00030.x","article-title":"Validity and reliability of the Migraine-Specific Quality of Life Questionnaire (MSQ Version 2.1)","volume":"40","author":"Martin","year":"2000","journal-title":"Headache"},{"key":"10.1016\/j.jns.2014.11.004_bb0170","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1080\/09638280802240498","article-title":"World Health Organisation Disability Assessment Schedule II: contribution to the Italian validation","volume":"31","author":"Federici","year":"2009","journal-title":"Disabil Rehabil"},{"key":"10.1016\/j.jns.2014.11.004_bb0175","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1046\/j.0333-1024.2001.00277.x","article-title":"The Migraine Disability Assessment (MIDAS) questionnaire: translation and reliability of the Italian version","volume":"21","author":"D'Amico","year":"2001","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0180","series-title":"Manual for the Beck Depression Inventory-II","author":"Beck","year":"1996"},{"key":"10.1016\/j.jns.2014.11.004_bb0185","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jns.2013.05.003","article-title":"OnabotulinumtoxinA for treatment of chronic migraine: PREEMPT 24-week pooled subgroup analysis of patients who had acute headache medication overuse at baseline","volume":"331","author":"Silberstein","year":"2013","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.jns.2014.11.004_bb0190","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1111\/j.1468-2982.2007.01326.x","article-title":"Topiramate reduces headache days in chronic migraine: a randomized, double-blind, placebo-controlled study","volume":"27","author":"Diener","year":"2007","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0195","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1212\/WNL.0b013e318232ab65","article-title":"Onabotulinumtoxin A improves quality of life and reduces impact of chronic migraine","volume":"77","author":"Lipton","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2014.11.004_bb0200","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1185\/030079906X104731","article-title":"The impact of migraine on daily activities: effect of topiramate compared with placebo","volume":"22","author":"Silberstein","year":"2006","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.jns.2014.11.004_bb0205","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.clinthera.2009.03.020","article-title":"Topiramate versus amitriptyline in migraine prevention: a 26-week, multicenter, randomized, double-blind, double-dummy, parallel-group noninferiority trial in adult migraineurs","volume":"31","author":"Dodick","year":"2009","journal-title":"Clin Ther"},{"key":"10.1016\/j.jns.2014.11.004_bb0210","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1111\/j.1468-2982.2009.01874.x","article-title":"Underdiagnosis and undertreatment of migraine in Italy: a survey of patients attending for the first time 10 headache centres","volume":"29","author":"Cevoli","year":"2009","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0215","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1526-4610.2011.01997.x","article-title":"Validating Migraine-Specific Quality of Life Questionnaire v2.1 in episodic and chronic migraine","volume":"52","author":"Bagley","year":"2012","journal-title":"Headache"},{"key":"10.1016\/j.jns.2014.11.004_bb0220","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1007\/s11136-012-0230-7","article-title":"The psychometric properties of the Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQ) in chronic migraine patients","volume":"22","author":"Rendas-Baum","year":"2013","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jns.2014.11.004_bb0225","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1007\/s11136-013-0556-9","article-title":"Validating the Migraine-Specific Quality of Life Questionnaire v2.1 (MSQ) in Italian inpatients with chronic migraine with a history of medication overuse","volume":"23","author":"Raggi","year":"2014","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jns.2014.11.004_bb0230","first-page":"S9","article-title":"The international classification of headache disorders: 2nd edition","volume":"24","author":"Headache Classification Subcommittee of the International Headache Society","year":"2004","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jns.2014.11.004_bb0235","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3102\/10769986006002107","article-title":"Distribution theory for Glass's estimator of effect size and related estimators","volume":"6","author":"Hedges","year":"1981","journal-title":"J Educ Behav Stat"},{"key":"10.1016\/j.jns.2014.11.004_bb0240","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1097\/00007632-200012150-00008","article-title":"SF-36 health survey update","volume":"25","author":"Ware","year":"2000","journal-title":"Spine"},{"key":"10.1016\/j.jns.2014.11.004_bb0245","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1007\/s11136-007-9217-1","article-title":"Validation of the Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQ v. 2.1) for patients undergoing prophylactic migraine treatment","volume":"16","author":"Cole","year":"2007","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jns.2014.11.004_bb0250","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1440-1819.2010.02093.x","article-title":"Correlations between alexithymia and pain severity, depression, and anxiety among patients with chronic and episodic migraine","volume":"64","author":"Yalug","year":"2010","journal-title":"Psychiatry Clin Neurosci"},{"key":"10.1016\/j.jns.2014.11.004_bb0255","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/MRR.0000000000000054","article-title":"Sociodemographic features and diagnoses as predictors of severe disability in a sample of adults applying for disability certification","volume":"37","author":"Raggi","year":"2014","journal-title":"Int J Rehabil Res"},{"key":"10.1016\/j.jns.2014.11.004_bb0260","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0140-6736(12)60240-2","article-title":"Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study","volume":"380","author":"Barnett","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2014.11.004_bb0265","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.pain.2009.01.013","article-title":"Excessive opioid use and the development of chronic migraine","volume":"142","author":"Bigal","year":"2009","journal-title":"Pain"},{"key":"10.1016\/j.jns.2014.11.004_bb0270","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1526-4610.2011.02050.x","article-title":"Opioid use and dependence among persons with migraine: results of the AMPP study","volume":"52","author":"Buse","year":"2012","journal-title":"Headache"},{"key":"10.1016\/j.jns.2014.11.004_bb0275","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1067\/mem.2002.121400","article-title":"Treatment patterns of isolated benign headache in US emergency departments","volume":"39","author":"Vinson","year":"2002","journal-title":"Ann Emerg Med"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X14007187?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X14007187?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:45:01Z","timestamp":1758383101000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X14007187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":55,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S0022510X14007187"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2014.11.004","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic migraine with medication overuse: Association between disability and quality of life measures, and impact of disease on patients' lives","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2014.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}