{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:18:22Z","timestamp":1787836702321,"version":"build-2784847793"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.jns.2016.04.040","type":"journal-article","created":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T20:53:29Z","timestamp":1462049609000},"page":"47-51","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Essential tremor-Parkinson's disease: A double whammy"],"prefix":"10.1016","volume":"366","author":[{"given":"Elan D.","family":"Louis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adina","family":"Wise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy N.","family":"Alcalay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwini K.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pam","family":"Factor-Litvak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2016.04.040_bb0005","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1136\/jnnp.2004.046292","article-title":"Long duration asymmetrical postural tremor is likely to predict development of Parkinson's disease and not essential tremor: clinical follow up study of 13 cases","volume":"76","author":"Chaudhuri","year":"2005","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jns.2016.04.040_bb0010","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.parkreldis.2006.05.033","article-title":"Exploring the relationship between essential tremor and Parkinson's disease","volume":"13","author":"Shahed","year":"2007","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0015","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1136\/jnnp.2008.147223","article-title":"Risk of incident Parkinson's disease and Parkinsonism in essential tremor: a population based study","volume":"80","author":"Benito-Leon","year":"2009","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jns.2016.04.040_bb0020","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1002\/mds.22161","article-title":"Emergence of Parkinson's disease in essential tremor: a study of the clinical correlates in 53 patients","volume":"23","author":"Minen","year":"2008","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0025","doi-asserted-by":"crossref","first-page":"335","DOI":"10.5334\/tohm.248","article-title":"Motor and non-motor features: differences between patients with isolated essential tremor and patients with both essential tremor and Parkinson's disease","volume":"5","author":"Ghika","year":"2015","journal-title":"Tremor Other Hyperkinet. Mov. (N.Y.)"},{"key":"10.1016\/j.jns.2016.04.040_bb0030","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.neuro.2013.11.005","article-title":"Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in Parkinson's disease","volume":"40","author":"Louis","year":"2014","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.jns.2016.04.040_bb0035","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/mds.10473","volume":"18","year":"2003","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0040","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/j.1532-5415.1968.tb02103.x","article-title":"Cumulative illness rating scale","volume":"16","author":"Linn","year":"1968","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.jns.2016.04.040_bb0045","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.parkreldis.2005.05.009","article-title":"Quality of life in Essential Tremor Questionnaire (QUEST): development and initial validation","volume":"11","author":"Troster","year":"2005","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0050","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1002\/1531-8257(200005)15:3<516::AID-MDS1015>3.0.CO;2-J","article-title":"Validity and test-retest reliability of a disability questionnaire for essential tremor","volume":"15","author":"Louis","year":"2000","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0055","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jns.2016.04.040_bb0060","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0749-3797(18)30622-6","article-title":"Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale)","volume":"10","author":"Andresen","year":"1994","journal-title":"Am. J. Prev. Med."},{"key":"10.1016\/j.jns.2016.04.040_bb0065","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"key":"10.1016\/j.jns.2016.04.040_bb0070","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res."},{"issue":"Suppl. 2","key":"10.1016\/j.jns.2016.04.040_bb0075","first-page":"S7","article-title":"Measuring balance in the elderly: validation of an instrument","volume":"83","author":"Berg","year":"1992","journal-title":"Can. J. Public Health"},{"key":"10.1016\/j.jns.2016.04.040_bb0080","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1002\/mds.21113","article-title":"Assessing fear of falling: can a short version of the Activities-specific Balance Confidence scale be useful?","volume":"21","author":"Peretz","year":"2006","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0085","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1532-5415.1991.tb01616.x","article-title":"The timed \u201cUp & Go\u201d: a test of basic functional mobility for frail elderly persons","volume":"39","author":"Podsiadlo","year":"1991","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.jns.2016.04.040_bb0090","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.parkreldis.2015.04.019","article-title":"Tremor-related quality of life: a comparison of essential tremor vs. Parkinson's disease patients","volume":"21","author":"Louis","year":"2015","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0095","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1001\/archneur.56.7.841","article-title":"Validity of a performance-based test of function in essential tremor","volume":"56","author":"Louis","year":"1999","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.jns.2016.04.040_bb0100","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/mds.870130215","article-title":"Reliability between two observers using a protocol for diagnosing essential tremor","volume":"13","author":"Louis","year":"1998","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0105","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1159\/000109681","article-title":"The Washington Heights-Inwood Genetic Study of Essential Tremor: methodologic issues in essential-tremor research","volume":"16","author":"Louis","year":"1997","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.jns.2016.04.040_bb0110","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1212\/WNL.42.6.1142","article-title":"What features improve the accuracy of clinical diagnosis in Parkinson's disease: a clinicopathologic study","volume":"42","author":"Hughes","year":"1992","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2016.04.040_bb0115","article-title":"Four essential tremor cases with moderately impaired gait: how impaired can gait be in this disease?","volume":"3","author":"Louis","year":"2013","journal-title":"Tremor Other Hyperkinet. Mov. (N.Y.)"},{"key":"10.1016\/j.jns.2016.04.040_bb0120","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.apmr.2006.07.255","article-title":"Functional mobility and postural control in essential tremor","volume":"87","author":"Parisi","year":"2006","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"10.1016\/j.jns.2016.04.040_bb0125","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/j.apmr.2013.02.020","article-title":"Using the Timed Up & Go test in a clinical setting to predict falling in Parkinson's disease","volume":"94","author":"Nocera","year":"2013","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"10.1016\/j.jns.2016.04.040_bb0130","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0167-4943(03)00082-7","article-title":"Predicting falls within the elderly community: comparison of postural sway, reaction time, the Berg balance scale and the Activities-specific Balance Confidence (ABC) scale for comparing fallers and non-fallers","volume":"38","author":"Lajoie","year":"2004","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/j.jns.2016.04.040_bb0135","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1212\/01.wnl.0000192393.05850.ec","article-title":"Population-based case-control study of cognitive function in essential tremor","volume":"66","author":"Benito-Leon","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2016.04.040_bb0140","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.parkreldis.2011.11.004","article-title":"Sleep in essential tremor: a comparison with normal controls and Parkinson's disease patients","volume":"18","author":"Gerbin","year":"2012","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.jns.2016.04.040_bb0145","doi-asserted-by":"crossref","first-page":"106","DOI":"10.3389\/fneur.2015.00106","article-title":"Poorer cognitive performance in patients with essential tremor-Parkinson's disease vs. patients with Parkinson's disease","volume":"6","author":"Louis","year":"2015","journal-title":"Front. Neurol."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X16302337?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X16302337?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,19]],"date-time":"2020-09-19T08:58:56Z","timestamp":1600505936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X16302337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":29,"alternative-id":["S0022510X16302337"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2016.04.040","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Essential tremor-Parkinson's disease: A double whammy","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2016.04.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}