{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:24:53Z","timestamp":1785795893176,"version":"3.56.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.jns.2016.08.029","type":"journal-article","created":{"date-parts":[[2016,8,16]],"date-time":"2016-08-16T02:30:22Z","timestamp":1471314622000},"page":"242-249","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"special_numbering":"C","title":["Chitinase expression in Alzheimer's disease and non-demented brains regions"],"prefix":"10.1016","volume":"369","author":[{"given":"C.","family":"Sanfilippo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Malaguarnera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Di Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jalz.2011.10.007","article-title":"National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease","volume":"8","author":"Hyman","year":"2012","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.jns.2016.08.029_bb0010","series-title":"Microglia in Alzheimer's Disease: The Good, the Bad and the Ugly","author":"Tejera","year":"2015"},{"issue":"5","key":"10.1016\/j.jns.2016.08.029_bb0015","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1365-2990.1992.tb00811.x","article-title":"The inflammatory response in the CNS","volume":"18","author":"Perry","year":"1992","journal-title":"Neuropathol. Appl. Neurobiol."},{"issue":"5726","key":"10.1016\/j.jns.2016.08.029_bb0020","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1126\/science.1110647","article-title":"Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo","volume":"308","author":"Nimmerjahn","year":"2005","journal-title":"Science"},{"issue":"2\u20133","key":"10.1016\/j.jns.2016.08.029_bb0025","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ijdevneu.2005.11.014","article-title":"Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms","volume":"24","author":"Sastre","year":"2006","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.jns.2016.08.029_bb0030","series-title":"Progress in Neurobiology","article-title":"Astrogliosis: an integral player in the pathogenesis of Alzheimer's disease","author":"Osborn","year":"2016"},{"key":"10.1016\/j.jns.2016.08.029_bb0035","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1750-1326-8-20","article-title":"Fluid biomarkers in Alzheimer's disease - current concepts","volume":"8","author":"Rosen","year":"2013","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.jns.2016.08.029_bb0040","doi-asserted-by":"crossref","DOI":"10.4061\/2010\/986310","article-title":"Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid","author":"Bjerke","year":"2010","journal-title":"Int. J. Alzheimers Dis."},{"issue":"10","key":"10.1016\/j.jns.2016.08.029_bb0045","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.biopsych.2010.08.025","article-title":"YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease","volume":"68","author":"Craig-Schapiro","year":"2010","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0050","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1159\/000362164","article-title":"Increased levels of chitotriosidase and YKL-40 in cerebrospinal fluid from patients with Alzheimer's disease","volume":"4","author":"Rosen","year":"2014","journal-title":"Dement. Geriatr. Cogn. Disord. Extra"},{"issue":"20","key":"10.1016\/j.jns.2016.08.029_bb0055","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1056\/NEJMe0706634","article-title":"Exoskeletons and exhalation","volume":"357","author":"Dickey","year":"2007","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"10.1016\/j.jns.2016.08.029_bb0060","doi-asserted-by":"crossref","first-page":"6770","DOI":"10.1074\/jbc.M009886200","article-title":"Identification of a novel acidic mammalian chitinase distinct from chitotriosidase","volume":"276","author":"Boot","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0065","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1046\/j.1432-1033.2003.03923.x","article-title":"Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase","volume":"271","author":"Synstad","year":"2004","journal-title":"Eur. J. Biochem.\/FEBS"},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0070","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00109-011-0803-x","article-title":"Genetic variants in candidate genes influencing NAFLD progression","volume":"90","author":"Di Rosa","year":"2012","journal-title":"J. Mol. Med."},{"issue":"8","key":"10.1016\/j.jns.2016.08.029_bb0075","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/j.biotechadv.2013.09.012","article-title":"From bacteria to human: a journey into the world of chitinases","volume":"31","author":"Adrangi","year":"2013","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.jns.2016.08.029_bb0080","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/920459","article-title":"Chitin, chitinase responses, and invasive fungal infections","volume":"2012","author":"Vega","year":"2012","journal-title":"Int. J. Microbiol."},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0085","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1534\/genetics.107.075846","article-title":"Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases","volume":"177","author":"Bussink","year":"2007","journal-title":"Genetics"},{"issue":"5","key":"10.1016\/j.jns.2016.08.029_bb0090","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1002\/jcb.22186","article-title":"Prolactin induces chitotriosidase expression in human macrophages through PTK, PI3-K, and MAPK pathways","volume":"107","author":"Di Rosa","year":"2009","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.jns.2016.08.029_bb0095","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/1471-2148-7-96","article-title":"Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family","volume":"7","author":"Funkhouser","year":"2007","journal-title":"BMC Evol. Biol."},{"issue":"8","key":"10.1016\/j.jns.2016.08.029_bb0100","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1182\/blood-2005-07-2843","article-title":"Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway","volume":"107","author":"Kzhyshkowska","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.jns.2016.08.029_bb0105","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1146\/annurev-physiol-012110-142250","article-title":"Role of chitin and chitinase\/chitinase-like proteins in inflammation, tissue remodeling, and injury","volume":"73","author":"Lee","year":"2011","journal-title":"Annu. Rev. Physiol."},{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0110","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1177\/1947601911402681","article-title":"Chitinase-like proteins are autoantigens in a model of inflammation-promoted incipient neoplasia","volume":"2","author":"Qureshi","year":"2011","journal-title":"Genes Cancer"},{"issue":"3","key":"10.1016\/j.jns.2016.08.029_bb0115","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1172\/JCI117084","article-title":"Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease","volume":"93","author":"Hollak","year":"1994","journal-title":"J. Clin. Investig."},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0120","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s12017-011-8147-9","article-title":"Cerebrospinal fluid microglial markers in Alzheimer's disease: elevated chitotriosidase activity but lack of diagnostic utility","volume":"13","author":"Mattsson","year":"2011","journal-title":"Neruomol. Med."},{"issue":"8","key":"10.1016\/j.jns.2016.08.029_bb0125","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1212\/WNL.0b013e318247caa1","article-title":"Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease","volume":"78","author":"Watabe-Rudolph","year":"2012","journal-title":"Neurology"},{"issue":"34","key":"10.1016\/j.jns.2016.08.029_bb0130","doi-asserted-by":"crossref","first-page":"25803","DOI":"10.1016\/S0021-9258(19)74461-5","article-title":"Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family","volume":"268","author":"Hakala","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jns.2016.08.029_bb0135","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1742-2094-7-34","article-title":"In vivo CHI3L1 (YKL-40) expression in astrocytes in acute and chronic neurological diseases","volume":"7","author":"Bonneh-Barkay","year":"2010","journal-title":"J. Neuroinflammation"},{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0140","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3233\/JAD-2012-120787","article-title":"Microglial markers are elevated in the prodromal phase of Alzheimer's disease and vascular dementia","volume":"33","author":"Olsson","year":"2013","journal-title":"J. Alzheimers Dis."},{"issue":"4","key":"10.1016\/j.jns.2016.08.029_bb0145","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"issue":"3","key":"10.1016\/j.jns.2016.08.029_bb0150","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.cell.2013.03.030","article-title":"Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease","volume":"153","author":"Zhang","year":"2013","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.jns.2016.08.029_bb0155","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.ajhg.2009.03.011","article-title":"Genetic control of human brain transcript expression in Alzheimer disease","volume":"84","author":"Webster","year":"2009","journal-title":"Am. J. Hum. Genet."},{"issue":"3","key":"10.1016\/j.jns.2016.08.029_bb0160","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1152\/physiolgenomics.00208.2006","article-title":"Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain","volume":"28","author":"Liang","year":"2007","journal-title":"Physiol. Genomics"},{"issue":"11","key":"10.1016\/j.jns.2016.08.029_bb0165","doi-asserted-by":"crossref","first-page":"4441","DOI":"10.1073\/pnas.0709259105","article-title":"Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons","volume":"105","author":"Liang","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0170","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1074\/mcp.M115.053256","article-title":"Protein-based classifier to predict conversion from clinically isolated syndrome to multiple sclerosis","volume":"15","author":"Borras","year":"2016","journal-title":"Mol. Cell. Proteomics: MCP"},{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0175","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13195-015-0142-1","article-title":"Cerebrospinal fluid VILIP-1 and YKL-40, candidate biomarkers to diagnose, predict and monitor Alzheimer's disease in a memory clinic cohort","volume":"7","author":"Kester","year":"2015","journal-title":"Alzheimers Res. Ther."},{"issue":"5","key":"10.1016\/j.jns.2016.08.029_bb0180","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1111\/ene.12960","article-title":"Cerebrospinal fluid chitinase-3-like 2 and chitotriosidase are potential prognostic biomarkers in early multiple sclerosis","volume":"23","author":"Mollgaard","year":"2016","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.jns.2016.08.029_bb0185","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1742-2094-3-27","article-title":"Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD","volume":"3","author":"Colton","year":"2006","journal-title":"J. Neuroinflammation"},{"issue":"9","key":"10.1016\/j.jns.2016.08.029_bb0190","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1001\/jamaneurol.2015.1285","article-title":"Longitudinal cerebrospinal fluid biomarker changes in preclinical Alzheimer disease during middle age","volume":"72","author":"Sutphen","year":"2015","journal-title":"JAMA Neurol."},{"issue":"10","key":"10.1016\/j.jns.2016.08.029_bb0195","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1111\/j.1460-9568.2006.04780.x","article-title":"Chitotriosidase and inflammatory mediator levels in Alzheimer's disease and cerebrovascular dementia","volume":"23","author":"Di Rosa","year":"2006","journal-title":"Eur. J. Neurosci."},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0200","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.clim.2015.10.003","article-title":"Role of CHI3L1 in neuroinflammation","volume":"161","author":"Wiley","year":"2015","journal-title":"Clin. Immunol."},{"issue":"7","key":"10.1016\/j.jns.2016.08.029_bb0205","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1212\/WNL.0000000000001859","article-title":"Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease","volume":"85","author":"Alcolea","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2016.08.029_bb0210","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3389\/fpsyg.2014.00074","article-title":"Visual cortex in aging and Alzheimer's disease: changes in visual field maps and population receptive fields","volume":"5","author":"Brewer","year":"2014","journal-title":"Front. Psychol."},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0215","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/WNR.0b013e32801198bc","article-title":"Expression of inflammatory genes in the primary visual cortex of late-stage Alzheimer's disease","volume":"18","author":"Cui","year":"2007","journal-title":"Neuroreport"},{"key":"10.1016\/j.jns.2016.08.029_bb0220","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jneuroim.2016.01.013","article-title":"YKL-40 is a CSF biomarker of intrathecal inflammation in secondary progressive multiple sclerosis","volume":"292","author":"Burman","year":"2016","journal-title":"J. Neuroimmunol."},{"issue":"6","key":"10.1016\/j.jns.2016.08.029_bb0225","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.neubiorev.2006.07.001","article-title":"Differential aging of the brain: patterns, cognitive correlates and modifiers","volume":"30","author":"Raz","year":"2006","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0230","doi-asserted-by":"crossref","first-page":"39","DOI":"10.7150\/ijbs.8.39","article-title":"Two closely related human members of chitinase-like family, CHI3L1 and CHI3L2, activate ERK1\/2 in 293 and U373 cells but have the different influence on cell proliferation","volume":"8","author":"Areshkov","year":"2012","journal-title":"Int. J. Biol. Sci."},{"issue":"5337","key":"10.1016\/j.jns.2016.08.029_bb0235","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1126\/science.278.5337.412","article-title":"Life and death of neurons in the aging brain","volume":"278","author":"Morrison","year":"1997","journal-title":"Science"},{"issue":"Suppl. 2","key":"10.1016\/j.jns.2016.08.029_bb0240","doi-asserted-by":"crossref","first-page":"S527","DOI":"10.3233\/JAD-2010-100501","article-title":"Why women have more Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid-beta peptide","volume":"20","author":"Vina","year":"2010","journal-title":"J. Alzheimer's Dis.: JAD"},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0245","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1177\/1535370215602785","article-title":"The impact of acute aerobic exercise on chitinase 3-like protein 1 and intelectin-1 expression in obesity","volume":"241","author":"Huang","year":"2016","journal-title":"Exp. Biol. Med."},{"issue":"5","key":"10.1016\/j.jns.2016.08.029_bb0250","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1159\/000444855","article-title":"Chitinase 3 like-1: an emerging molecule involved in diabetes and diabetic complications","volume":"83","author":"Di Rosa","year":"2016","journal-title":"Pathobiology"},{"issue":"7","key":"10.1016\/j.jns.2016.08.029_bb0255","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0133672","article-title":"Associations of the inflammatory marker YKL-40 with measures of obesity and dyslipidaemia in individuals at high risk of type 2 diabetes","volume":"10","author":"Thomsen","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jns.2016.08.029_bb0260","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1196\/annals.1297.005","article-title":"The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: modification by age, sex, and APOE polymorphism","volume":"1019","author":"Corder","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jns.2016.08.029_bb0265","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.neurobiolaging.2016.02.011","article-title":"Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's disease","volume":"42","author":"Zhao","year":"2016","journal-title":"Neurobiol. Aging"},{"issue":"4\u20135","key":"10.1016\/j.jns.2016.08.029_bb0270","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.acthis.2015.02.010","article-title":"Different pediatric brain tumors are associated with different gene expression profiling","volume":"117","author":"Di Rosa","year":"2015","journal-title":"Acta Histochem."},{"issue":"6","key":"10.1016\/j.jns.2016.08.029_bb0275","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1007\/s00415-010-5872-1","article-title":"Volume reduction in subcortical regions according to severity of Alzheimer's disease","volume":"258","author":"Roh","year":"2011","journal-title":"J. Neurol."},{"issue":"4","key":"10.1016\/j.jns.2016.08.029_bb0280","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1136\/jnnp.71.4.515","article-title":"A disorder of colour perception associated with abnormal colour after-images: a defect of the primary visual cortex","volume":"71","author":"Chan","year":"2001","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"2","key":"10.1016\/j.jns.2016.08.029_bb0285","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.pscychresns.2008.11.002","article-title":"The neural basis of visuospatial perception in Alzheimer's disease and healthy elderly comparison subjects: an fMRI study","volume":"172","author":"Thiyagesh","year":"2009","journal-title":"Psychiatry Res."},{"issue":"3","key":"10.1016\/j.jns.2016.08.029_bb0290","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0733-8619(02)00107-X","article-title":"Visual dysfunction, neurodegenerative diseases, and aging","volume":"21","author":"Jackson","year":"2003","journal-title":"Neurol. Clin."},{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0295","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.archger.2014.10.011","article-title":"Abnormal retinal nerve fiber layer thickness and macula lutea in patients with mild cognitive impairment and Alzheimer's disease","volume":"60","author":"Gao","year":"2015","journal-title":"Arch. Gerontol. Geriatr."},{"issue":"1","key":"10.1016\/j.jns.2016.08.029_bb0300","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1212\/WNL.52.1.71","article-title":"Neuroanatomic correlates of visual agnosia in Alzheimer's disease: a clinicopathologic study","volume":"52","author":"Giannakopoulos","year":"1999","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.jns.2016.08.029_bb0305","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF03033910","article-title":"The role of novel chitin-like polysaccharides in Alzheimer disease","volume":"12","author":"Castellani","year":"2007","journal-title":"Neurotox. Res."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X16305202?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X16305202?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T21:31:24Z","timestamp":1657056684000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X16305202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":61,"alternative-id":["S0022510X16305202"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2016.08.029","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chitinase expression in Alzheimer's disease and non-demented brains regions","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2016.08.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}