{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T11:02:30Z","timestamp":1761994950266,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.jns.2017.01.011","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T15:05:09Z","timestamp":1483628709000},"page":"258-262","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Urinary albumin-to-creatinine ratio is associated with white matter lesions severity in first-ever stroke patients"],"prefix":"10.1016","volume":"373","author":[{"given":"Satoshi","family":"Suda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Kanamaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Okubo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junya","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Shimoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikako","family":"Nito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Ishiwata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumi","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1\u20132","key":"10.1016\/j.jns.2017.01.011_bb0005","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.jns.2014.09.012","article-title":"Clinical and demographic predictors of mild cognitive impairment for converting to Alzheimer's disease and reverting to normal cognition","volume":"346","author":"Tokuchi","year":"2014","journal-title":"J. Neurol. Sci."},{"issue":"10 Suppl","key":"10.1016\/j.jns.2017.01.011_bb0010","first-page":"S139","article-title":"Leukoaraiosis and stroke","volume":"41","author":"Smith","year":"2010","journal-title":"Stroke"},{"issue":"6","key":"10.1016\/j.jns.2017.01.011_bb0015","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1136\/jnnp.2008.154633","article-title":"Deep frontal and periventricular age related white matter changes but not basal ganglia and infratentorial hyperintensities are associated with falls: cross sectional results from the LADIS study","volume":"80","author":"Blahak","year":"2009","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"2","key":"10.1016\/j.jns.2017.01.011_bb0020","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1212\/WNL.0b013e3181e7ca05","article-title":"White matter changes and diabetes predict cognitive decline in the elderly: the LADIS study","volume":"75","author":"Verdelho","year":"2010","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.jns.2017.01.011_bb0025","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S1474-4422(10)70104-6","article-title":"Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges","volume":"9","author":"Pantoni","year":"2010","journal-title":"Lancet Neurol."},{"issue":"Pt 4","key":"10.1016\/j.jns.2017.01.011_bb0030","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1093\/brain\/aww009","article-title":"Longitudinal patterns of leukoaraiosis and brain atrophy in symptomatic small vessel disease","volume":"139","author":"Lambert","year":"2016","journal-title":"Brain"},{"issue":"7","key":"10.1016\/j.jns.2017.01.011_bb0035","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S1474-4422(07)70170-9","article-title":"Silent brain infarcts: a systematic review","volume":"6","author":"Vermeer","year":"2007","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2017.01.011_bb0040","doi-asserted-by":"crossref","first-page":"c4249","DOI":"10.1136\/bmj.c4249","article-title":"Low glomerular filtration rate and risk of stroke: meta-analysis","volume":"341","author":"Lee","year":"2010","journal-title":"BMJ"},{"issue":"5","key":"10.1016\/j.jns.2017.01.011_bb0045","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1159\/000317069","article-title":"Level of albuminuria and risk of stroke: systematic review and meta-analysis","volume":"30","author":"Lee","year":"2010","journal-title":"Cerebrovasc. Dis."},{"issue":"24","key":"10.1016\/j.jns.2017.01.011_bb0050","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1212\/WNL.0b013e318259e110","article-title":"Proteinuria and clinical outcomes after ischemic stroke","volume":"78","author":"Kumai","year":"2012","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.jns.2017.01.011_bb0055","doi-asserted-by":"crossref","first-page":"c246","DOI":"10.1159\/000320342","article-title":"Association between albuminuria, glomerular filtration rate and mortality or recurrence in stroke patients","volume":"117","author":"Lima","year":"2011","journal-title":"Nephron Clin. Pract."},{"key":"10.1016\/j.jns.2017.01.011_bb0060","doi-asserted-by":"crossref","first-page":"438978","DOI":"10.4061\/2011\/438978","article-title":"Connecting cerebral white matter lesions and hypertensive target organ damage","volume":"2011","author":"Sierra","year":"2011","journal-title":"J. Aging Res."},{"issue":"1","key":"10.1016\/j.jns.2017.01.011_bb0065","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1161\/01.HYP.0000168052.00426.65","article-title":"Relationship between aortic stiffening and microvascular disease in brain and kidney: cause and logic of therapy","volume":"46","author":"O'Rourke","year":"2005","journal-title":"Hypertension"},{"issue":"24","key":"10.1016\/j.jns.2017.01.011_bb0070","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1212\/WNL.0b013e318259e29f","article-title":"The cerebro-renal interaction in stroke neurology","volume":"78","author":"Toyoda","year":"2012","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.jns.2017.01.011_bb0075","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1161\/01.STR.24.1.35","article-title":"Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment","volume":"24","author":"Adams","year":"1993","journal-title":"Stroke"},{"issue":"6","key":"10.1016\/j.jns.2017.01.011_bb0080","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1053\/j.ajkd.2008.12.034","article-title":"Revised equations for estimated GFR from serum creatinine in Japan","volume":"53","author":"Matsuo","year":"2009","journal-title":"Am. J. Kidney Dis."},{"issue":"2","key":"10.1016\/j.jns.2017.01.011_bb0085","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2214\/ajr.149.2.351","article-title":"MR signal abnormalities at 1.5T in Alzheimer's dementia and normal aging","volume":"149","author":"Fazekas","year":"1987","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.jns.2017.01.011_bb0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000346944","article-title":"Cerebrorenal interaction and stroke","volume":"179","author":"Toyoda","year":"2013","journal-title":"Contrib. Nephrol."},{"issue":"7","key":"10.1016\/j.jns.2017.01.011_bb0095","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1093\/ndt\/gfv009","article-title":"Chronic kidney disease and the risk of stroke: a systematic review and meta-analysis","volume":"30","author":"Masson","year":"2015","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.jns.2017.01.011_bb0100","article-title":"The cerebrovascular-chronic kidney disease connection: perspectives and mechanisms","author":"Lau","year":"2016","journal-title":"Transl. Stroke Res."},{"issue":"8","key":"10.1016\/j.jns.2017.01.011_bb0105","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1016\/j.neurobiolaging.2011.04.008","article-title":"Vascular inflammation in cerebral small vessel disease","volume":"33","author":"Rouhl","year":"2012","journal-title":"Neurobiol. Aging"},{"issue":"2","key":"10.1016\/j.jns.2017.01.011_bb0110","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1093\/brain\/awg040","article-title":"Markers of endothelial dysfunction in lacunar infarction and ischaemic leukoaraiosis","volume":"126","author":"Hassan","year":"2003","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.jns.2017.01.011_bb0115","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1093\/aje\/kwp429","article-title":"Invited commentary: albuminuria and microvascular disease of the brain\u2014a shared pathophysiology","volume":"171","author":"Knopman","year":"2010","journal-title":"Am. J. Epidemiol."},{"issue":"2","key":"10.1016\/j.jns.2017.01.011_bb0120","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1161\/STROKEAHA.113.003164","article-title":"Impact of albuminuria on early neurological deterioration and lesion volume expansion in lenticulostriate small infarcts","volume":"45","author":"Umemura","year":"2014","journal-title":"Stroke"},{"issue":"8","key":"10.1016\/j.jns.2017.01.011_bb0125","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1111\/ene.12127","article-title":"Prediction of hemorrhagic transformation in acute ischaemic stroke by micro- and macroalbuminuria after intravenous thrombolysis","volume":"20","author":"Cho","year":"2013","journal-title":"Eur. J. Neurol."},{"issue":"13","key":"10.1016\/j.jns.2017.01.011_bb0130","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1212\/WNL.0000000000002527","article-title":"Chronic kidney disease, cerebral blood flow, and white matter volume in hypertensive adults","volume":"86","author":"Tamura","year":"2016","journal-title":"Neurology"},{"issue":"1\u20132","key":"10.1016\/j.jns.2017.01.011_bb0135","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1159\/000445168","article-title":"Microalbuminuria and the combination of MRI markers of cerebral small vessel disease","volume":"42","author":"Vilar-Bergua","year":"2016","journal-title":"Cerebrovasc. Dis."},{"issue":"7","key":"10.1016\/j.jns.2017.01.011_bb0140","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1161\/STROKEAHA.114.004900","article-title":"Association of kidney disease measures with ischemic versus hemorrhagic strokes: pooled analyses of 4 prospective community-based cohorts","volume":"45","author":"Mahmoodi","year":"2014","journal-title":"Stroke"},{"issue":"19","key":"10.1016\/j.jns.2017.01.011_bb0145","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.2174\/0929867321666131227155140","article-title":"Essential hypertension, cerebral white matter pathology and ischemic stroke","volume":"21","author":"Sierra","year":"2014","journal-title":"Curr. Med. Chem."},{"issue":"Suppl. 1","key":"10.1016\/j.jns.2017.01.011_bb0150","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000051184","article-title":"A review on blood pressure and ischaemic white matter lesions","volume":"9","author":"Skoog","year":"1998","journal-title":"Dement. Geriatr. Cogn. Disord."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X17300114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X17300114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:47:38Z","timestamp":1758383258000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X17300114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":30,"alternative-id":["S0022510X17300114"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2017.01.011","relation":{},"ISSN":["0022-510X"],"issn-type":[{"type":"print","value":"0022-510X"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urinary albumin-to-creatinine ratio is associated with white matter lesions severity in first-ever stroke patients","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2017.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}