{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:57:14Z","timestamp":1786993034954,"version":"build-2736575974"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004162","name":"Meath Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004162","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Irish Institute of Clinical Neuroscience (IICN)\/Novartis Ireland Fellowship Grant"},{"name":"The Irish Heart Foundation Stroke Prevention Bursary"},{"name":"Biogen Idec Ireland"},{"name":"Joint IICN\/Merck Serono Fellowship in Neuroscience Grant"},{"DOI":"10.13039\/501100004162","name":"The Meath Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004162","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Trinity College Dublin Innovation Bursary"},{"name":"Bayer Healthcare Ireland"},{"name":"Elitech UK"},{"name":"Verum Diagnostica GmbH"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.jns.2017.04.014","type":"journal-article","created":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T00:16:23Z","timestamp":1491956183000},"page":"227-233","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Clinical outcomes and a high prevalence of abnormalities on comprehensive arterial and venous thrombophilia screening in TIA or ischaemic stroke patients with a patent foramen ovale, an inter\u00adatrial septal aneurysm or both"],"prefix":"10.1016","volume":"377","author":[{"given":"Soon Tjin","family":"Lim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.X.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre R.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Gil","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"McCabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny","family":"McHugh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominick J.H.","family":"McCabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0005","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0025-6196(12)60336-X","article-title":"Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts","volume":"59","author":"Hagen","year":"1984","journal-title":"Mayo Clin. Proc."},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0010","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/jnnp.2006.092031","article-title":"Antithrombotic and interventional treatment options in cardioembolic transient ischaemic attack and ischaemic stroke","volume":"78","author":"McCabe","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0015","first-page":"15","article-title":"Patent foramen ovale: an anatomical study. Apropos of 500 consecutive autopsies","volume":"87","author":"Penther","year":"1994","journal-title":"Arch. Mal. Coeur Vaiss."},{"issue":"7","key":"10.1016\/j.jns.2017.04.014_bb0020","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1161\/CIRCULATIONAHA.104.524371","article-title":"Patent foramen ovale and stroke","volume":"112","author":"Homma","year":"2005","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jns.2017.04.014_bb0025","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1161\/01.STR.31.2.398","article-title":"Significant association of atrial vulnerability with atrial septal abnormalities in young patients with ischemic stroke of unknown cause","volume":"31","author":"Berthet","year":"2000","journal-title":"Stroke"},{"issue":"3","key":"10.1016\/j.jns.2017.04.014_bb0030","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1161\/hs0302.104543","article-title":"Clinical and imaging findings in cryptogenic stroke patients with and without patent foramen ovale: the PFO-ASA Study","volume":"33","author":"Lamy","year":"2002","journal-title":"Stroke"},{"issue":"18","key":"10.1016\/j.jns.2017.04.014_bb0035","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1056\/NEJM198805053181802","article-title":"Prevalence of patent foramen ovale in patients with stroke","volume":"318","author":"Lechat","year":"1988","journal-title":"N. Engl. J. Med."},{"issue":"8601","key":"10.1016\/j.jns.2017.04.014_bb0040","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0140-6736(88)92944-3","article-title":"Patent foramen ovale in young stroke patients","volume":"2","author":"Webster","year":"1988","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.jns.2017.04.014_bb0045","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1161\/01.STR.24.12.1865","article-title":"Atrial septal aneurysm and patent foramen ovale as risk factors for cryptogenic stroke in patients less than 55 years of age. A study using transesophageal echocardiography","volume":"24","author":"Cabanes","year":"1993","journal-title":"Stroke"},{"issue":"22","key":"10.1016\/j.jns.2017.04.014_bb0050","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1161\/01.CIR.0000017498.88393.44","article-title":"Effect of medical treatment in stroke patients with patent foramen ovale: patent foramen ovale in Cryptogenic Stroke Study","volume":"105","author":"Homma","year":"2002","journal-title":"Circulation"},{"issue":"22","key":"10.1016\/j.jns.2017.04.014_bb0055","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1056\/NEJMoa071422","article-title":"Patent foramen ovale and cryptogenic stroke in older patients","volume":"357","author":"Handke","year":"2007","journal-title":"N. Engl. J. Med."},{"issue":"24","key":"10.1016\/j.jns.2017.04.014_bb0060","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1056\/NEJMoa011503","article-title":"Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both","volume":"345","author":"Mas","year":"2001","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0065","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1161\/STR.0b013e3181f7d043","article-title":"Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"42","author":"Furie","year":"2011","journal-title":"Stroke"},{"issue":"7","key":"10.1016\/j.jns.2017.04.014_bb0070","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1161\/STR.0000000000000024","article-title":"Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"45","author":"Kernan","year":"2014","journal-title":"Stroke"},{"issue":"11","key":"10.1016\/j.jns.2017.04.014_bb0075","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1056\/NEJMoa1009639","article-title":"Closure or medical therapy for cryptogenic stroke with patent foramen ovale","volume":"366","author":"Furlan","year":"2012","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.jns.2017.04.014_bb0080","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2013-004282","article-title":"Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale","volume":"4","author":"Spencer","year":"2014","journal-title":"BMJ Open"},{"issue":"12","key":"10.1016\/j.jns.2017.04.014_bb0085","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1056\/NEJMoa1211716","article-title":"Percutaneous closure of patent foramen ovale in cryptogenic embolism","volume":"368","author":"Meier","year":"2013","journal-title":"N. Engl. J. Med."},{"issue":"12","key":"10.1016\/j.jns.2017.04.014_bb0090","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1056\/NEJMoa1301440","article-title":"Closure of patent foramen ovale versus medical therapy after cryptogenic stroke","volume":"368","author":"Carroll","year":"2013","journal-title":"N. Engl. J. Med."},{"issue":"8790","key":"10.1016\/j.jns.2017.04.014_bb0095","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/0140-6736(92)90085-H","article-title":"Clinical examination in diagnosis and subclassification of stroke","volume":"339","author":"Bamford","year":"1992","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.jns.2017.04.014_bb0100","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1159\/000131083","article-title":"Guidelines for management of ischaemic stroke and transient ischaemic attack","volume":"25","author":"European Stroke Organisation Executive, C","year":"2008","journal-title":"Cerebrovasc. Dis."},{"issue":"7","key":"10.1016\/j.jns.2017.04.014_bb0105","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1007\/s00415-014-7362-3","article-title":"Longitudinal assessment of von Willebrand factor antigen and von Willebrand factor propeptide in response to alteration of antiplatelet therapy after TIA or ischaemic stroke","volume":"261","author":"Tobin","year":"2014","journal-title":"J. Neurol."},{"issue":"7","key":"10.1016\/j.jns.2017.04.014_bb0110","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1111\/jth.12277","article-title":"Increased platelet activation in early symptomatic vs. asymptomatic carotid stenosis and relationship with microembolic status: results from the Platelets and Carotid Stenosis Study","volume":"11","author":"Kinsella","year":"2013","journal-title":"J. Thromb. Haemost."},{"issue":"1\u20132","key":"10.1016\/j.jns.2017.04.014_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-510X(96)00308-5","article-title":"European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke","volume":"143","author":"Diener","year":"1996","journal-title":"J. Neurol. Sci."},{"issue":"4","key":"10.1016\/j.jns.2017.04.014_bb0120","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1161\/STROKEAHA.107.496281","article-title":"Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis","volume":"39","author":"Verro","year":"2008","journal-title":"Stroke"},{"issue":"7329","key":"10.1016\/j.jns.2017.04.014_bb0125","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.324.7329.71","article-title":"Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients","volume":"324","year":"2002","journal-title":"BMJ"},{"issue":"9523","key":"10.1016\/j.jns.2017.04.014_bb0130","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/S0140-6736(06)68734-5","article-title":"Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial","volume":"367","author":"Halkes","year":"2006","journal-title":"Lancet"},{"issue":"9038","key":"10.1016\/j.jns.2017.04.014_bb0135","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(96)09457-3","article-title":"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)","volume":"348","author":"CAPRIE Steering Committee","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2017.04.014_bb0140","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jns.2015.12.009","article-title":"Continuation and adherence rates on initially-prescribed intensive secondary prevention therapy after Rapid Access Stroke Prevention (RASP) service assessment","volume":"361","author":"Murphy","year":"2016","journal-title":"J. Neurol. Sci."},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0145","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1161\/01.STR.24.1.35","article-title":"Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment","volume":"24","author":"Adams","year":"1993","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.jns.2017.04.014_bb0150","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1538-7836.2006.01753.x","article-title":"International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)","volume":"4","author":"Miyakis","year":"2006","journal-title":"J. Thromb. Haemost."},{"issue":"9176","key":"10.1016\/j.jns.2017.04.014_bb0155","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0140-6736(98)11058-9","article-title":"Homocysteine and vascular disease","volume":"354","author":"Hankey","year":"1999","journal-title":"Lancet"},{"issue":"16","key":"10.1016\/j.jns.2017.04.014_bb0160","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1001\/jama.288.16.2015","article-title":"Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis","volume":"288","year":"2002","journal-title":"JAMA"},{"issue":"9","key":"10.1016\/j.jns.2017.04.014_bb0165","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1161\/STROKEAHA.115.009136","article-title":"Elevated total homocysteine levels in acute ischemic stroke are associated with long-term mortality","volume":"46","author":"Shi","year":"2015","journal-title":"Stroke"},{"issue":"11","key":"10.1016\/j.jns.2017.04.014_bb0170","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.numecd.2014.05.011","article-title":"Homocysteine level and risk of different stroke types: a meta-analysis of prospective observational studies","volume":"24","author":"He","year":"2014","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"issue":"15","key":"10.1016\/j.jns.2017.04.014_bb0175","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1212\/WNL.0b013e3182a823cc","article-title":"Vitamin B supplementation, homocysteine levels, and the risk of cerebrovascular disease: a meta-analysis","volume":"81","author":"Ji","year":"2013","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.jns.2017.04.014_bb0180","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1136\/jnnp.65.4.508","article-title":"Inherited prothrombotic states and ischaemic stroke in childhood","volume":"65","author":"Ganesan","year":"1998","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"2","key":"10.1016\/j.jns.2017.04.014_bb0185","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1177\/1076029613488936","article-title":"Factor VIII in the setting of acute ischemic stroke among patients with suspected hypercoagulable state","volume":"20","author":"Chang","year":"2014","journal-title":"Clin. Appl. Thromb. Hemost."},{"issue":"8","key":"10.1016\/j.jns.2017.04.014_bb0190","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.amjcard.2004.06.056","article-title":"Comparison of results of percutaneous closure of patent foramen ovale for paradoxical embolism in patients with versus without thrombophilia","volume":"94","author":"Giardini","year":"2004","journal-title":"Am. J. Cardiol."},{"issue":"8","key":"10.1016\/j.jns.2017.04.014_bb0195","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1161\/01.STR.32.8.1793","article-title":"Inherited thrombophilia in ischemic stroke and its pathogenic subtypes","volume":"32","author":"Hankey","year":"2001","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.jns.2017.04.014_bb0200","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1055\/s-0038-1656061","article-title":"High prevalence of elevated factor VIII levels in patients referred for thrombophilia screening: role of increased synthesis and relationship to the acute phase reaction","volume":"77","author":"O'Donnell","year":"1997","journal-title":"Thromb. Haemost."},{"issue":"5","key":"10.1016\/j.jns.2017.04.014_bb0205","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1055\/s-0037-1614553","article-title":"Increased levels of factor VIII and fibrinogen in patients with venous thrombosis are not caused by acute phase reactions","volume":"81","author":"Kamphuisen","year":"1999","journal-title":"Thromb. Haemost."},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0210","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1055\/s-0037-1613748","article-title":"Elevation of FVIII: C in venous thromboembolism is persistent and independent of the acute phase response","volume":"83","author":"O'Donnell","year":"2000","journal-title":"Thromb. Haemost."},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0215","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1055\/s-0037-1613747","article-title":"High plasma concentration of factor VIIIc is a major risk factor for venous thromboembolism","volume":"83","author":"Kraaijenhagen","year":"2000","journal-title":"Thromb. Haemost."},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0220","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1161\/01.STR.0000046457.54037.CC","article-title":"Inherited thrombophilic disorders in young adults with ischemic stroke and patent foramen ovale","volume":"34","author":"Pezzini","year":"2003","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.jns.2017.04.014_bb0225","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1159\/000070120","article-title":"Prothrombin G20210A mutation, but not factor V Leiden, is a risk factor in patients with persistent foramen ovale and otherwise unexplained cerebral ischemia","volume":"16","author":"Lichy","year":"2003","journal-title":"Cerebrovasc. Dis."},{"issue":"3","key":"10.1016\/j.jns.2017.04.014_bb0230","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/01.mbc.0000061288.28953.c8","article-title":"Factor V Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale","volume":"14","author":"Karttunen","year":"2003","journal-title":"Blood Coagul. Fibrinolysis"},{"issue":"10","key":"10.1016\/j.jns.2017.04.014_bb0235","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s004150050262","article-title":"Prevalence of factor V Leiden mutation in young adults with cerebral ischaemia: a case-control study on 225 patients","volume":"245","author":"Nabavi","year":"1998","journal-title":"J. Neurol."},{"issue":"12","key":"10.1016\/j.jns.2017.04.014_bb0240","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1161\/01.STR.0000038094.79901.3B","article-title":"Cryptogenic stroke in relation to genetic variation in clotting factors and other genetic polymorphisms among young men and women","volume":"33","author":"Austin","year":"2002","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.jns.2017.04.014_bb0245","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1160\/TH07-04-0243","article-title":"Thrombophilia in young patients with cryptogenic stroke and patent foramen ovale (PFO)","volume":"98","author":"Offelli","year":"2007","journal-title":"Thromb. Haemost."},{"issue":"6","key":"10.1016\/j.jns.2017.04.014_bb0250","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/MBC.0b013e3281420398","article-title":"Patent foramen ovale and prothrombotic markers in young stroke patients","volume":"18","author":"Belvis","year":"2007","journal-title":"Blood Coagul. Fibrinolysis"},{"issue":"7","key":"10.1016\/j.jns.2017.04.014_bb0255","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1212\/WNL.0b013e3182a08d59","article-title":"An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke","volume":"81","author":"Kent","year":"2013","journal-title":"Neurology"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X17302484?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X17302484?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T19:26:52Z","timestamp":1569007612000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X17302484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":51,"alternative-id":["S0022510X17302484"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2017.04.014","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical outcomes and a high prevalence of abnormalities on comprehensive arterial and venous thrombophilia screening in TIA or ischaemic stroke patients with a patent foramen ovale, an inter\u00adatrial septal aneurysm or both","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2017.04.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}