{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:48:39Z","timestamp":1788385719646,"version":"build-2803163510"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100006977","name":"Indiana State Department of Health","doi-asserted-by":"publisher","award":["#204200"],"award-info":[{"award-number":["#204200"]}],"id":[{"id":"10.13039\/100006977","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#NS073636"],"award-info":[{"award-number":["#NS073636"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.jns.2017.05.039","type":"journal-article","created":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T13:32:24Z","timestamp":1495459944000},"page":"29-35","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Exogenous Acrolein intensifies sensory hypersensitivity after spinal cord injury in rat"],"prefix":"10.1016","volume":"379","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0592-0944","authenticated-orcid":false,"given":"Breanne","family":"Butler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Acosta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7297-9428","authenticated-orcid":false,"given":"Riyi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0005","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.brainresrev.2008.12.010","article-title":"Mechanisms of chronic central neuropathic pain after spinal cord injury","volume":"60","author":"Hulsebosch","year":"2009","journal-title":"Brain Res. Rev."},{"issue":"8","key":"10.1016\/j.jns.2017.05.039_bb0010","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1089\/neu.1997.14.517","article-title":"Chronic central pain after spinal cord injury","volume":"14","author":"Christensen","year":"1997","journal-title":"J. Neurotrauma"},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0015","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s40122-015-0033-y","article-title":"Management of Neuropathic Pain Associated with spinal cord injury","volume":"4","author":"Hagen","year":"2015","journal-title":"Pain Ther"},{"issue":"6951","key":"10.1016\/j.jns.2017.05.039_bb0020","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1038\/nature01868","article-title":"Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain","volume":"424","author":"Coull","year":"2003","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.jns.2017.05.039_bb0025","doi-asserted-by":"crossref","first-page":"4017","DOI":"10.1523\/JNEUROSCI.23-10-04017.2003","article-title":"p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain","volume":"23","author":"Jin","year":"2003","journal-title":"J. Neurosci."},{"issue":"1\u20132","key":"10.1016\/j.jns.2017.05.039_bb0030","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.pain.2004.12.022","article-title":"ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model","volume":"114","author":"Zhuang","year":"2005","journal-title":"Pain"},{"issue":"3","key":"10.1016\/j.jns.2017.05.039_bb0035","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/j.1471-4159.2008.05622.x","article-title":"Critical role of acrolein in secondary injury following ex vivo spinal cord trauma","volume":"107","author":"Hamann","year":"2008","journal-title":"J. Neurochem."},{"issue":"6","key":"10.1016\/j.jns.2017.05.039_bb0040","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1111\/j.1471-4159.2009.06395.x","article-title":"Acrolein scavenging: a potential novel mechanism of attenuating oxidative stress following spinal cord injury","volume":"111","author":"Hamann","year":"2009","journal-title":"J. Neurochem."},{"issue":"9","key":"10.1016\/j.jns.2017.05.039_bb0045","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1002\/mnfr.201100217","article-title":"Acrolein-mediated injury in nervous system trauma and diseases","volume":"55","author":"Shi","year":"2011","journal-title":"Mol. Nutr. Food Res."},{"issue":"11","key":"10.1016\/j.jns.2017.05.039_bb0050","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1038\/nn1992","article-title":"The neuropathic pain triad: neurons, immune cells and glia","volume":"10","author":"Scholz","year":"2007","journal-title":"Nat. Neurosci."},{"issue":"5","key":"10.1016\/j.jns.2017.05.039_bb0055","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.neuropharm.2010.12.030","article-title":"GABA and central neuropathic pain following spinal cord injury","volume":"60","author":"Gwak","year":"2011","journal-title":"Neuropharmacology"},{"issue":"7070","key":"10.1016\/j.jns.2017.05.039_bb0060","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/nature04223","article-title":"BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain","volume":"438","author":"Coull","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.jns.2017.05.039_bb0065","doi-asserted-by":"crossref","unstructured":"B.C. Hains, J.P. Klein, C.Y. Saab, M.J. Craner, J.A. Black, S.G. Waxman, Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury, J Neurosci 23(26) (2003) 8881\u201392.","DOI":"10.1523\/JNEUROSCI.23-26-08881.2003"},{"issue":"5","key":"10.1016\/j.jns.2017.05.039_bb0070","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1111\/jnc.13352","article-title":"Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury","volume":"135","author":"Park","year":"2015","journal-title":"J. Neurochem."},{"issue":"2","key":"10.1016\/j.jns.2017.05.039_bb0075","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/jnc.13639","article-title":"Mitigation of sensory and motor deficits by acrolein scavenger phenelzine in a rat model of spinal cord contusive injury","volume":"138","author":"Chen","year":"2016","journal-title":"J. Neurochem."},{"issue":"2","key":"10.1016\/j.jns.2017.05.039_bb0080","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1111\/jnc.12628","article-title":"Neuroprotective role of hydralazine in rat spinal cord injury-attenuation of acrolein-mediated damage","volume":"129","author":"Park","year":"2014","journal-title":"J. Neurochem."},{"issue":"8","key":"10.1016\/j.jns.2017.05.039_bb0085","doi-asserted-by":"crossref","first-page":"E746","DOI":"10.1073\/pnas.1300083110","article-title":"Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine a","volume":"110","author":"Yu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/j.jns.2017.05.039_bb0090","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/sc.2008.136","article-title":"Management of neuropathic pain following spinal cord injury: now and in the future","volume":"47","author":"Siddall","year":"2009","journal-title":"Spinal Cord"},{"issue":"2","key":"10.1016\/j.jns.2017.05.039_bb0095","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.neuropharm.2008.10.008","article-title":"Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain","volume":"56","author":"Hama","year":"2009","journal-title":"Neuropharmacology"},{"issue":"4","key":"10.1016\/j.jns.2017.05.039_bb0100","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.neuron.2012.02.039","article-title":"TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord","volume":"74","author":"Kim","year":"2012","journal-title":"Neuron"},{"issue":"5","key":"10.1016\/j.jns.2017.05.039_bb0105","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1111\/jnc.12500","article-title":"Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat","volume":"128","author":"Due","year":"2014","journal-title":"J. Neurochem."},{"issue":"10","key":"10.1016\/j.jns.2017.05.039_bb0110","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1212\/01.wnl.0000244422.45278.ff","article-title":"Pregabalin in central neuropathic pain associated with spinal cord injury: a placebo-controlled trial","volume":"67","author":"Siddall","year":"2006","journal-title":"Neurology"},{"issue":"1\u20132","key":"10.1016\/j.jns.2017.05.039_bb0115","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.pain.2007.06.033","article-title":"Pregabalin in patients with central neuropathic pain: a randomized, double-blind, placebo-controlled trial of a flexible-dose regimen","volume":"136","author":"Vranken","year":"2008","journal-title":"Pain"},{"issue":"7","key":"10.1016\/j.jns.2017.05.039_bb0120","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1097\/01.BRS.0000112068.16108.3A","article-title":"Gabapentin is a first line drug for the treatment of neuropathic pain in spinal cord injury","volume":"29","author":"Levendoglu","year":"2004","journal-title":"Spine (Phila Pa 1976)"},{"issue":"2","key":"10.1016\/j.jns.2017.05.039_bb0125","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1080\/10790268.2002.11753609","article-title":"Gabapentin in the treatment of neuropathic pain after spinal cord injury: a prospective, randomized, double-blind, crossover trial","volume":"25","author":"Tai","year":"2002","journal-title":"J Spinal Cord Med"},{"issue":"12","key":"10.1016\/j.jns.2017.05.039_bb0130","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1016\/j.apmr.2007.07.038","article-title":"Comparison of the effectiveness of amitriptyline and gabapentin on chronic neuropathic pain in persons with spinal cord injury","volume":"88","author":"Rintala","year":"2007","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"6","key":"10.1016\/j.jns.2017.05.039_bb0135","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1212\/WNL.0b013e318281546b","article-title":"A randomized trial of pregabalin in patients with neuropathic pain due to spinal cord injury","volume":"80","author":"Cardenas","year":"2013","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.jns.2017.05.039_bb0140","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0304-3959(01)00483-3","article-title":"Efficacy of amitriptyline for relief of pain in spinal cord injury: results of a randomized controlled trial","volume":"96","author":"Cardenas","year":"2002","journal-title":"Pain"},{"issue":"3 Pt 2","key":"10.1016\/j.jns.2017.05.039_bb0145","first-page":"32","article-title":"A double-blind controlled clinical trial of fluoxetine and amitriptyline in the treatment of outpatients with major depressive disorder","volume":"46","author":"Chouinard","year":"1985","journal-title":"J Clin Psychiatry"},{"issue":"4246","key":"10.1016\/j.jns.2017.05.039_bb0150","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1126\/science.1273597","article-title":"Analgesia mediated by a direct spinal action of narcotics","volume":"192","author":"Yaksh","year":"1976","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.jns.2017.05.039_bb0155","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1097\/00000539-200012000-00037","article-title":"The efficacy of intrathecal morphine and clonidine in the treatment of pain after spinal cord injury","volume":"91","author":"Siddall","year":"2000","journal-title":"Anesth. Analg."},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0160","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1682\/JRRD.2008.04.0051","article-title":"Transcutaneous electrical nerve stimulation for treatment of spinal cord injury neuropathic pain","volume":"46","author":"Norrbrink","year":"2009","journal-title":"J. Rehabil. Res. Dev."},{"issue":"4","key":"10.1016\/j.jns.2017.05.039_bb0165","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/sc.2012.159","article-title":"The effect of low-frequency TENS in the treatment of neuropathic pain in patients with spinal cord injury","volume":"51","author":"Celik","year":"2013","journal-title":"Spinal Cord"},{"key":"10.1016\/j.jns.2017.05.039_bb0170","doi-asserted-by":"crossref","unstructured":"P.J. Siddall, M.J. Cousins, Persistent pain as a disease entity: implications for clinical management, Anesthesia and analgesia 99(2) (2004) 510\u201320, table of contents.","DOI":"10.1213\/01.ANE.0000133383.17666.3A"},{"issue":"2","key":"10.1016\/j.jns.2017.05.039_bb0175","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.bbrc.2008.11.054","article-title":"Acrolein toxicity: comparison with reactive oxygen species","volume":"378","author":"Yoshida","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"5","key":"10.1016\/j.jns.2017.05.039_bb0180","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S1050-1738(99)00016-X","article-title":"Current status of acrolein as a lipid peroxidation product","volume":"9","author":"Uchida","year":"1999","journal-title":"Trends in Cardiovascular Medicine"},{"issue":"2","key":"10.1016\/j.jns.2017.05.039_bb0185","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1046\/j.1471-4159.1999.0720751.x","article-title":"Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease","volume":"72","author":"Calingasan","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jns.2017.05.039_bb0190","first-page":"22","article-title":"The role of acrolein in spinal cord injury","volume":"2","author":"Shi","year":"2006","journal-title":"Applied Neurology"},{"issue":"7","key":"10.1016\/j.jns.2017.05.039_bb0195","doi-asserted-by":"crossref","first-page":"888","DOI":"10.3109\/10715762.2015.1021696","article-title":"Molecular mechanisms of acrolein-mediated myelin destruction in CNS trauma and disease","volume":"49","author":"Shi","year":"2015","journal-title":"Free Radic. Res."},{"issue":"6","key":"10.1016\/j.jns.2017.05.039_bb0200","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.cell.2006.02.023","article-title":"TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents","volume":"124","author":"Bautista","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.jns.2017.05.039_bb0205","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1146\/annurev-physiol-030212-183811","article-title":"TRPA1: a gatekeeper for inflammation","volume":"75","author":"Bautista","year":"2013","journal-title":"Annu. Rev. Physiol."},{"issue":"32","key":"10.1016\/j.jns.2017.05.039_bb0210","first-page":"3013","article-title":"Transient receptor potential channel A1 involved in calcitonin gene-related peptide release in neurons","volume":"8","author":"Ushio","year":"2013","journal-title":"Neural Regen. Res."},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0215","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1093\/toxsci\/kfn106","article-title":"Nonredundant functions of alphabeta and gammadelta T cells in acrolein-induced pulmonary pathology","volume":"105","author":"Borchers","year":"2008","journal-title":"Toxicol. Sci."},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0220","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0891-5849(91)90192-6","article-title":"Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes","volume":"11","author":"Esterbauer","year":"1991","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jns.2017.05.039_bb0225","doi-asserted-by":"crossref","unstructured":"F. Facchinetti, F. Amadei, P. Geppetti, F. Tarantini, C. Di Serio, A. Dragotto, P.M. Gigli, S. Catinella, M. Civelli, R. Patacchini, Alpha,beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages, Am. J. Respir. Cell Mol. Biol. 37(5) (2007) 617\u201323.","DOI":"10.1165\/rcmb.2007-0130OC"},{"issue":"6 Pt 1","key":"10.1016\/j.jns.2017.05.039_bb0230","first-page":"L1149","article-title":"Smoke extract stimulates lung fibroblasts to release neutrophil and monocyte chemotactic activities","volume":"277","author":"Sato","year":"1999","journal-title":"Am. J. Phys."},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0235","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/mnfr.200700412","article-title":"Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease","volume":"52","author":"Stevens","year":"2008","journal-title":"Mol. Nutr. Food Res."},{"issue":"7","key":"10.1016\/j.jns.2017.05.039_bb0240","doi-asserted-by":"crossref","first-page":"677","DOI":"10.4103\/1673-5374.131564","article-title":"Acrolein as a novel therapeutic target for motor and sensory deficits in spinal cord injury","volume":"9","author":"Park","year":"2014","journal-title":"Neural Regen. Res."},{"issue":"3","key":"10.1016\/j.jns.2017.05.039_bb0245","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s11064-005-2602-7","article-title":"Accumulation of acrolein-protein adducts after traumatic spinal cord injury","volume":"30","author":"Luo","year":"2005","journal-title":"Neurochem. Res."},{"issue":"4","key":"10.1016\/j.jns.2017.05.039_bb0250","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1080\/10790268.2005.11753829","article-title":"Effects of smoking on neuropathic pain in two people with spinal cord injury","volume":"28","author":"Richards","year":"2005","journal-title":"J Spinal Cord Med"},{"issue":"7","key":"10.1016\/j.jns.2017.05.039_bb0255","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1021\/tx700075y","article-title":"Quantitation of acrolein-derived (3-hydroxypropyl)mercapturic acid in human urine by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: effects of cigarette smoking","volume":"20","author":"Carmella","year":"2007","journal-title":"Chem. Res. Toxicol."},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0260","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1167\/iovs.06-0248","article-title":"Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid","volume":"48","author":"Jia","year":"2007","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.jns.2017.05.039_bb0265","doi-asserted-by":"crossref","unstructured":"T. Schettgen, A. Musiol, T. Kraus, Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and N,N-dimethylformamide (AMCC) in human urine using liquid chromatography\/tandem mass spectrometry, Rapid Commun. Mass Spectrom. 22(17) (2008) 2629\u201338.","DOI":"10.1002\/rcm.3659"},{"issue":"6","key":"10.1016\/j.jns.2017.05.039_bb0270","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s12264-014-1480-x","article-title":"Acute systemic accumulation of acrolein in mice by inhalation at a concentration similar to that in cigarette smoke","volume":"30","author":"Tully","year":"2014","journal-title":"Neurosci. Bull."},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0275","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of tactile allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"J. Neurosci. Methods"},{"issue":"15","key":"10.1016\/j.jns.2017.05.039_bb0280","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1089\/neu.2013.2888","article-title":"Determination of urine 3-HPMA, a stable Acrolein metabolite in a rat model of spinal cord injury","volume":"30","author":"Zheng","year":"2013","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.jns.2017.05.039_bb0285","doi-asserted-by":"crossref","unstructured":"P.X. Chen, S.C. Moldoveanu, Mainstream Smoke Chemical Analyses for 2R4F Kentucky Reference Cigarette, Contrib. to Tob. Res 20 (2003).","DOI":"10.2478\/cttr-2013-0760"},{"issue":"4","key":"10.1016\/j.jns.2017.05.039_bb0290","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"4","key":"10.1016\/j.jns.2017.05.039_bb0295","first-page":"281","article-title":"Pain in paraplegia; clinical management and surgical treatment","volume":"47","author":"Botterell","year":"1954","journal-title":"Proc R Soc Med"},{"issue":"3","key":"10.1016\/j.jns.2017.05.039_bb0300","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/08958370701864151","article-title":"Respiratory tract responses in male rats following subchronic acrolein inhalation","volume":"20","author":"Dorman","year":"2008","journal-title":"Inhal. Toxicol."},{"issue":"10","key":"10.1016\/j.jns.2017.05.039_bb0305","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1093\/carcin\/11.10.1863","article-title":"Analysis of 1,3-butadiene and other selected gas-phase components in cigarette mainstream and sidestream smoke by gas chromatography-mass selective detection","volume":"11","author":"Brunnemann","year":"1990","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.jns.2017.05.039_bb0310","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1176\/ajp.117.4.361","article-title":"Clinical and theoretical observations on phenelzine (nardil), an antidepressant agent","volume":"117","author":"Cole","year":"1960","journal-title":"Am. J. Psychiatry"},{"issue":"8","key":"10.1016\/j.jns.2017.05.039_bb0315","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/0306-3623(94)90352-2","article-title":"Pharmacological and clinical implications of MAO-B inhibitors","volume":"25","author":"Yu","year":"1994","journal-title":"Gen. Pharmacol."},{"issue":"3","key":"10.1016\/j.jns.2017.05.039_bb0320","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1007\/s12031-012-9867-5","article-title":"Transcriptional and translational plasticity in rodent urinary bladder TRP channels with urinary bladder inflammation, bladder dysfunction, or postnatal maturation","volume":"48","author":"Merrill","year":"2012","journal-title":"J. Mol. Neurosci."},{"issue":"13","key":"10.1016\/j.jns.2017.05.039_bb0325","doi-asserted-by":"crossref","first-page":"5603","DOI":"10.1523\/JNEUROSCI.1806-12.2013","article-title":"TRPV1 and TRPA1 antagonists prevent the transition of acute to chronic inflammation and pain in chronic pancreatitis","volume":"33","author":"Schwartz","year":"2013","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0330","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0022-5347(05)67495-2","article-title":"Cyclophosphamide-induced cystitis in freely-moving conscious rats: behavioral approach to a new model of visceral pain","volume":"164","author":"Boucher","year":"2000","journal-title":"J. Urol."},{"issue":"4","key":"10.1016\/j.jns.2017.05.039_bb0335","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF00173510","article-title":"Cause and prevention of mafosfamide-induced venous pain","volume":"4","author":"Hilgard","year":"1986","journal-title":"Investig. New Drugs"},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0340","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.pain.2010.08.021","article-title":"TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation","volume":"152","author":"Kunkler","year":"2011","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.jns.2017.05.039_bb0345","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.pain.2007.08.024","article-title":"Pain associated with multiple sclerosis: systematic review and proposed classification","volume":"137","author":"O'Connor","year":"2008","journal-title":"Pain"},{"issue":"5","key":"10.1016\/j.jns.2017.05.039_bb0350","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.ejpain.2004.11.005","article-title":"Central pain in multiple sclerosis--prevalence and clinical characteristics","volume":"9","author":"Osterberg","year":"2005","journal-title":"Eur. J. Pain"},{"issue":"3","key":"10.1016\/j.jns.2017.05.039_bb0355","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.pain.2005.01.015","article-title":"Sensory function and quality of life in patients with multiple sclerosis and pain","volume":"114","author":"Svendsen","year":"2005","journal-title":"Pain"},{"key":"10.1016\/j.jns.2017.05.039_bb0360","doi-asserted-by":"crossref","unstructured":"T.Z. Fischer, S.G. Waxman, Neuropathic pain in diabetes--evidence for a central mechanism, Nat Rev Neurol 6(8) 462\u20136.","DOI":"10.1038\/nrneurol.2010.90"},{"key":"10.1016\/j.jns.2017.05.039_bb0365","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envres.2016.03.015","article-title":"Acrolein metabolites, diabetes and insulin resistance","volume":"148","author":"Feroe","year":"2016","journal-title":"Environ. Res."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X17303362?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X17303362?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T18:57:52Z","timestamp":1569351472000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X17303362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":73,"alternative-id":["S0022510X17303362"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2017.05.039","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exogenous Acrolein intensifies sensory hypersensitivity after spinal cord injury in rat","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2017.05.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}