{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:53:21Z","timestamp":1790142801366,"version":"4.0.1"},"reference-count":7,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01AG047975"],"award-info":[{"award-number":["R01AG047975"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01AG026484"],"award-info":[{"award-number":["R01AG026484"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["P50AG005134"],"award-info":[{"award-number":["P50AG005134"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["K23AG02872605"],"award-info":[{"award-number":["K23AG02872605"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.jns.2017.09.015","type":"journal-article","created":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T17:45:58Z","timestamp":1505238358000},"page":"10-12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Total small vessel disease burden and brain network efficiency in cerebral amyloid angiopathy"],"prefix":"10.1016","volume":"382","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4975-3754","authenticated-orcid":false,"given":"Raffaella","family":"Valenti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael D.","family":"Reijmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Charidimou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregoire","family":"Boulouis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergi Ramirez","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis","family":"Fotiadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Jessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Ayres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Riley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Pantoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Edip Gurol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M.","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Viswanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2017.09.015_bb0005","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S1474-4422(14)70003-1","article-title":"Outcome markers for clinical trials in cerebral amyloid angiopathy","volume":"13","author":"Greenberg","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2017.09.015_bb0010","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1016\/j.neurobiolaging.2015.06.024","article-title":"Total MRI load of cerebral small vessel disease and cognitive ability in older people","volume":"36","author":"Staals","year":"2015","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.jns.2017.09.015_bb0015","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1001\/jamaneurol.2016.0832","article-title":"Total magnetic resonance imaging burden of small vessel disease in cerebral amyloid Angiopathy: an imaging-pathologic study of concept validation","volume":"73","author":"Charidimou","year":"2016","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.jns.2017.09.015_bb0020","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/brain\/awu316","article-title":"Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy","volume":"138","author":"Reijmer","year":"2015","journal-title":"Brain J. Neurol."},{"key":"10.1016\/j.jns.2017.09.015_bb0025","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1212\/WNL.56.4.537","article-title":"Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria","volume":"56","author":"Knudsen","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2017.09.015_bb0030","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S1474-4422(13)70124-8","article-title":"Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration","volume":"12","author":"Wardlaw","year":"2013","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2017.09.015_bb0035","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1212\/WNL.0b013e31828f1876","article-title":"Topography of dilated perivascular spaces in subjects from a memory clinic cohort","volume":"80","author":"Martinez-Ramirez","year":"2013","journal-title":"Neurology"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X1734296X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X1734296X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,13]],"date-time":"2020-03-13T16:52:07Z","timestamp":1584118327000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X1734296X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":7,"alternative-id":["S0022510X1734296X"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2017.09.015","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Total small vessel disease burden and brain network efficiency in cerebral amyloid angiopathy","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2017.09.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}