{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T21:13:40Z","timestamp":1768079620960,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.jns.2018.04.042","type":"journal-article","created":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T05:35:10Z","timestamp":1525066510000},"page":"222-226","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Migraine as possible red flag of PFO presence in suspected demyelinating disease"],"prefix":"10.1016","volume":"390","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5753-6752","authenticated-orcid":false,"given":"E.","family":"Signoriello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Cirillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Puoti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Signoriello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Negro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Koci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.B.","family":"Melone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rapacciuolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Maresca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Lus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2018.04.042_bb0005","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1526-4610.1992.hed3206287.x","article-title":"The prevalence of cerebral damage varies with migraine type: a MRI study","volume":"32","author":"Fazekas","year":"1992","journal-title":"Headache"},{"issue":"8","key":"10.1016\/j.jns.2018.04.042_bb0010","first-page":"499","article-title":"Study of the relationship between white matter lesions in the magnetic resonance imaging and patent foramen ovale","volume":"23","author":"Bosca","year":"2008","journal-title":"Neurologia"},{"key":"10.1016\/j.jns.2018.04.042_bb0015","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1093\/brain\/120.11.2059","article-title":"Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis","volume":"120","author":"Barkhof","year":"1997","journal-title":"Brain"},{"key":"10.1016\/j.jns.2018.04.042_bb0020","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1212\/01.wnl.0000335764.14513.1a","article-title":"Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome","volume":"72","author":"Okuda","year":"2009","journal-title":"Neurology"},{"issue":"9","key":"10.1016\/j.jns.2018.04.042_bb0025","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1177\/0333102413485658","article-title":"The international classification of headache disorders, 3rd edition (beta version)","volume":"33","author":"Headache classification Committee of the International Headache Society (IHS)","year":"2013","journal-title":"Cephalalgia"},{"issue":"4","key":"10.1016\/j.jns.2018.04.042_bb0030","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/ana.24609","article-title":"Transcranial Doppler versus transthoracic echocardiography for the detection of patent foramen ovale in patients with cryptogenic cerebral ischemia: a systematic review and diagnostic test accuracy meta-analysis","volume":"79","author":"Katsanos","year":"2016","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jns.2018.04.042_bb0035","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1161\/01.STR.29.3.725","article-title":"Consensus on microembolus detection by TCD","volume":"29","author":"Ringelstein","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2018.04.042_bb0040","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1212\/WNL.53.3.537","article-title":"Ferrari MD,et al. the prevalence and characteristics of migraine in a population-based cohort: the GEM study","volume":"53","author":"Launer","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2018.04.042_bb0045","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s11916-005-0039-y","article-title":"Migraine and white matter hyperintensities","volume":"9","author":"Porter","year":"2005","journal-title":"Curr. Pain Headache Rep."},{"key":"10.1016\/j.jns.2018.04.042_bb0050","doi-asserted-by":"crossref","unstructured":"Okuda TD. Incidental MRI anomalies suggestive of multiple sclerosis, the radiologically isolated syndrome. Neurology 2009. 72(14):1284.","DOI":"10.1212\/01.wnl.0000335764.14513.1a"},{"issue":"8","key":"10.1016\/j.jns.2018.04.042_bb0055","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1177\/1352458512471874","article-title":"Prevalence of brain magnetic resonance imaging meeting Barkhof and Mc Donald criteria for dissemination in space among headache patients","volume":"19","author":"Liu","year":"2013","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.jns.2018.04.042_bb0060","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s10072-007-0805-1","article-title":"Multiple sclerosis and headache co-morbidity. A case-control study","volume":"28","author":"Vacca","year":"2007","journal-title":"Neurol. Sci."},{"issue":"22","key":"10.1016\/j.jns.2018.04.042_bb0065","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1212\/WNL.0000000000004686","article-title":"Assessing association of comorbidities with treatment choice and persistence in MS: a real-life multicenter study","volume":"89","author":"Laroni","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2018.04.042_bb0070","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1177\/1352458511416487","article-title":"Increased risk of multiple sclerosis among women with migraine in the Nurses' health study II","volume":"18","author":"Kister","year":"2012","journal-title":"Mult. Scler."},{"key":"10.1016\/j.jns.2018.04.042_bb0075","series-title":"Status Migrainosus as an Initial Presentation of Multiple Sclerosis","first-page":"28","volume":"4","author":"Alroughani","year":"2015"},{"key":"10.1016\/j.jns.2018.04.042_bb0080","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1046\/j.1526-4610.2001.01140.x","article-title":"Immunological aspects in migraine: increase of IL-10 plasma levels during attack","volume":"41","author":"Munno","year":"2001","journal-title":"Headache"},{"key":"10.1016\/j.jns.2018.04.042_bb0085","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3389\/fneur.2014.00099","article-title":"Migraine and patent foramen ovale: barking up the wrong tree?","volume":"5","author":"Morelli","year":"2014","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jns.2018.04.042_bb0090","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s10194-005-0154-5","article-title":"High prevalence of patent foramen ovale in migraine with aura","volume":"6","author":"Ferrarini","year":"2005","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.jns.2018.04.042_bb0095","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1161\/CIRCULATIONAHA.107.727271","volume":"117","author":"Dowson","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jns.2018.04.042_bb0100","first-page":"1","article-title":"The contemporary spectrum of multiple sclerosis misdiagnosis","volume":"87","author":"Salomon","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2018.04.042_bb0105","first-page":"171","article-title":"The diagnosis of multiple sclerosis: pinpointing the concept of 'no better explanation'","volume":"20","author":"Calabrese","year":"2014","journal-title":"Mult. Scler. J."},{"issue":"5","key":"10.1016\/j.jns.2018.04.042_bb0110","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.amjmed.2013.12.006","article-title":"Patent foramen ovale and migraine attacks: a systematic review","volume":"127","author":"Philomena","year":"2014","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jns.2018.04.042_bb0115","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s10194-005-0154-5","article-title":"High prevalence of patent foramen ovale in migraine with aura","volume":"6","author":"Ferrarini","year":"2005","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.jns.2018.04.042_bb0120","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0140-6736(72)90412-6","article-title":"Migraine: a pulmonary disease?","volume":"18","author":"Sandler","year":"1972","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2018.04.042_bb0125","first-page":"362","article-title":"Does patent foramen ovale promote cryptogenic stroke and migraine headache?","volume":"32","author":"Tobis","year":"2005","journal-title":"Tex. Heart Inst. J."},{"key":"10.1016\/j.jns.2018.04.042_bb0130","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000454840","article-title":"Ulf Schminke. Posterior versus anterior circulation stroke in young adults: a comparative study of stroke Aetiologies and risk factors in stroke among young Fabry patients (sifap1)","volume":"43","author":"von Sarnowski","year":"2017","journal-title":"Cerebrovasc. Dis."},{"key":"10.1016\/j.jns.2018.04.042_bb0135","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1093\/brain\/awh542","article-title":"Infarcts in the posterior circulation territory in migraine. The population based MRI CAMERA study","volume":"128","author":"Kruit","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.jns.2018.04.042_bb0140","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1159\/000375152","article-title":"Prevalence of patent foramen ovale in ischaemic stroke in Italy: results of SISIFO study","volume":"39","author":"Consoli","year":"2015","journal-title":"Cerebrovasc. Dis."},{"key":"10.1016\/j.jns.2018.04.042_bb0145","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/j.1468-2982.2008.01544.x","article-title":"White matter lesions in migraine and right-to-left shunt: a conventional and diffusion MRI study","volume":"28","author":"Del Sette","year":"2008","journal-title":"Cephalalgia"},{"issue":"42","key":"10.1016\/j.jns.2018.04.042_bb0150","first-page":"859","article-title":"Kazuki Fukuchi. Embolic Distribution Through Patent Foramen Ovale Demonstrated by 99mTc-MAA Brain SPECT After Valsalva Radionuclide Venography","volume":"6","author":"Hayashida","year":"2001","journal-title":"J. Nuc. Med."},{"issue":"3","key":"10.1016\/j.jns.2018.04.042_bb0155","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/bja\/aet122","article-title":"Sympathetic regulation of cerebral blood flow in humans: a review","volume":"111","author":"Laan","year":"2013","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.jns.2018.04.042_bb0160","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1007\/s00415-010-5613-5","article-title":"Role of sympathetic nervous system in activity-induced cerebral perfusion","volume":"257","author":"Gierthm\u03cbhlen","year":"2010","journal-title":"J. Neurol."},{"issue":"3","key":"10.1016\/j.jns.2018.04.042_bb0165","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1371\/journal.pone.0090509","article-title":"Radiologically isolated syndrome: 5-year risk for an initial clinical event","volume":"9","author":"Okuda","year":"2014","journal-title":"PLoS One"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X18302132?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X18302132?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T00:56:05Z","timestamp":1534899365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X18302132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":33,"alternative-id":["S0022510X18302132"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2018.04.042","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Migraine as possible red flag of PFO presence in suspected demyelinating disease","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2018.04.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}