{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:41:48Z","timestamp":1788871308272,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Science Foundation for Young Scientists of China","award":["ZR2016HB37"],"award-info":[{"award-number":["ZR2016HB37"]}]},{"name":"National Science Foundation for Young Scientists of China","award":["ZR2017PH027"],"award-info":[{"award-number":["ZR2017PH027"]}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["81100972"],"award-info":[{"award-number":["81100972"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["81701058"],"award-info":[{"award-number":["81701058"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.jns.2019.01.038","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T23:29:03Z","timestamp":1548372543000},"page":"184-191","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":106,"special_numbering":"C","title":["The role of repetitive transcranial magnetic stimulation (rTMS) in the treatment of cognitive impairment in patients with Alzheimer's disease: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"398","author":[{"given":"Yan","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jing","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Yan","family":"Shan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-Hua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2160-1484","authenticated-orcid":false,"given":"Lin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jns.2019.01.038_bb0005","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s40279-017-0787-y","article-title":"Physical activity in preventing Alzheimer's disease and cognitive decline: a narrative review","volume":"48","author":"Brini","year":"2018","journal-title":"Sports Med."},{"issue":"1","key":"10.1016\/j.jns.2019.01.038_bb0010","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jalz.2012.11.007","article-title":"The global prevalence of dementia: a systematic review and metaanalysis","volume":"9","author":"Prince","year":"2013","journal-title":"Alzheimer's Dement."},{"key":"10.1016\/j.jns.2019.01.038_bb0015","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.archger.2017.07.017","article-title":"Cognitive interventions in patients with dementia living in long-term care facilities: systematic review and meta-analysis","volume":"73","author":"Folkerts","year":"2017","journal-title":"Arch. Gerontol. Geriatr."},{"issue":"5","key":"10.1016\/j.jns.2019.01.038_bb0020","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1002\/med.21434","article-title":"Drugs in clinical trials for Alzheimer's disease: the major trends","volume":"37","author":"Bachurin","year":"2017","journal-title":"Med. Res. Rev."},{"issue":"7","key":"10.1016\/j.jns.2019.01.038_bb0025","doi-asserted-by":"crossref","first-page":"823","DOI":"10.2174\/1871527315666160518124759","article-title":"Early development of symptomatic drugs in AD: a systematic review of the use of biomarkers","volume":"15","author":"Deguil","year":"2016","journal-title":"CNS Neurol. Disord. Drug Targets"},{"issue":"12","key":"10.1016\/j.jns.2019.01.038_bb0030","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1007\/s00702-016-1606-6","article-title":"Repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training is a safe and effective modality for the treatment of Alzheimer's disease: clinical experience","volume":"123","author":"Rabey","year":"2016","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.jns.2019.01.038_bb0035","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s40035-015-0045-x","article-title":"Transcranial magnetic stimulation to understand pathophysiology and as potential treatment for neurodegenerative diseases","volume":"4","author":"Ni","year":"2015","journal-title":"Transl. Neurodegener."},{"issue":"Pt 7","key":"10.1016\/j.jns.2019.01.038_bb0040","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1093\/brain\/aww118","article-title":"Transcranial magnetic stimulation and potential cortical and trigeminothalamic mechanisms in migraine","volume":"139","author":"Andreou","year":"2016","journal-title":"Brain"},{"issue":"11","key":"10.1016\/j.jns.2019.01.038_bb0045","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.clinph.2014.05.021","article-title":"Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)","volume":"125","author":"Lefaucheur","year":"2014","journal-title":"Clin. Neurophysiol."},{"issue":"1","key":"10.1016\/j.jns.2019.01.038_bb0050","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1002\/gps.4726","article-title":"Effects of repetitive transcranial magnetic stimulation on improvement of cognition in elderly patients with cognitive impairment: a systematic review and meta-analysis","volume":"33","author":"Cheng","year":"2018","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"7","key":"10.1016\/j.jns.2019.01.038_bb0055","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1212\/WNL.0000000000004232","article-title":"Transcranial magnetic stimulation distinguishes Alzheimer's disease from frontotemporal dementia","volume":"89","author":"Benussi","year":"2017","journal-title":"Neurology"},{"issue":"1\u20132","key":"10.1016\/j.jns.2019.01.038_bb0060","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jns.2014.01.037","article-title":"Cognitive effects of repetitive transcranial magnetic stimulation in patients with neurodegenerative diseases - clinician's perspective","volume":"339","author":"Anderkova","year":"2014","journal-title":"J. Neurol. Sci."},{"issue":"2","key":"10.1016\/j.jns.2019.01.038_bb0065","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3233\/JAD-150346","article-title":"Repetitive transcranial magnetic stimulation as an alternative therapy for cognitive impairment in Alzheimer's disease: a meta-analysis","volume":"48","author":"Liao","year":"2015","journal-title":"J. Alzheimer's Dis."},{"key":"10.1016\/j.jns.2019.01.038_bb0070","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomized trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"issue":"7","key":"10.1016\/j.jns.2019.01.038_bb0075","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1136\/jnnp.2009.197848","article-title":"Improved language performance in Alzheimer's disease following brain stimulation","volume":"82","author":"Cotelli","year":"2011","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"5","key":"10.1016\/j.jns.2019.01.038_bb0080","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.clinph.2011.09.010","article-title":"Chronic treatment with rivastigmine in patients with Alzheimer's disease: a study on primary motor cortex excitability tested by 5\u202fHz-repetitive transcranial magnetic stimulation","volume":"123","author":"Trebbastoni","year":"2012","journal-title":"Clin. Neurophysiol."},{"issue":"1\u20132","key":"10.1016\/j.jns.2019.01.038_bb0085","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jns.2014.08.036","article-title":"Non-invasive brain stimulation of the right inferior frontal gyrus may improve attention in early Alzheimer's disease: a pilot study","volume":"346","author":"Eliasova","year":"2014","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.jns.2019.01.038_bb0090","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.neuroimage.2017.12.048","article-title":"Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease","volume":"169","author":"Koch","year":"2018","journal-title":"NeuroImage"},{"issue":"12","key":"10.1016\/j.jns.2019.01.038_bb0095","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1111\/j.1468-1331.2008.02202.x","article-title":"Transcranial magnetic stimulation improves naming in Alzheimer's disease patients at different stages of cognitive decline","volume":"15","author":"Cotelli","year":"2008","journal-title":"Eur. J. Neurol."},{"issue":"3","key":"10.1016\/j.jns.2019.01.038_bb0100","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s00702-010-0578-1","article-title":"Beneficial effect of repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease: a proof of concept study","volume":"118","author":"Bentwich","year":"2011","journal-title":"J. Neural Transm."},{"issue":"1","key":"10.1016\/j.jns.2019.01.038_bb0105","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s00415-011-6128-4","article-title":"Effects of low versus high frequencies of repetitive transcranial magnetic stimulation on cognitive function and cortical excitability in Alzheimer's dementia","volume":"259","author":"Ahmed","year":"2012","journal-title":"J. Neurol."},{"issue":"1","key":"10.1016\/j.jns.2019.01.038_bb0110","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3988\/jcn.2016.12.1.57","article-title":"Treatment of Alzheimer's disease with repetitive transcranial Magnetic stimulation combined with cognitive training: a prospective, randomized, double-blind, placebo-controlled study","volume":"12","author":"Lee","year":"2016","journal-title":"J. Clin. Neurol."},{"issue":"20","key":"10.1016\/j.jns.2019.01.038_bb0115","doi-asserted-by":"crossref","first-page":"33864","DOI":"10.18632\/oncotarget.13060","article-title":"Repetitive transcranial magnetic stimulation improves cognitive function of Alzheimer's disease patients","volume":"8","author":"Zhao","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.jns.2019.01.038_bb0120","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.neucli.2017.01.001","article-title":"Repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease","volume":"47","author":"Nguyen","year":"2017","journal-title":"Neurophysiol. Clin."},{"issue":"5","key":"10.1016\/j.jns.2019.01.038_bb0125","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/s00702-012-0902-z","article-title":"Repetitive transcranial magnetic stimulation combined with cognitive training is a safe and effective modality for the treatment of Alzheimer's disease: a randomized, double-blind study","volume":"120","author":"Rabey","year":"2013","journal-title":"J. Neural Transm. (Vienna)"},{"issue":"6","key":"10.1016\/j.jns.2019.01.038_bb0130","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/ane.12223","article-title":"Transcranial magnetic stimulation (TMS)\/repetitive TMS in mild cognitive impairment and Alzheimer's disease","volume":"129","author":"Nardone","year":"2014","journal-title":"Acta Neurol. Scand."},{"issue":"3","key":"10.1016\/j.jns.2019.01.038_bb0135","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.brs.2011.03.003","article-title":"A case report of daily left prefrontal repetitive transcranial magnetic stimulation (rTMS) as an adjunctive treatment for Alzheimer's disease","volume":"5","author":"Haffen","year":"2012","journal-title":"Brain Stimul."},{"key":"10.1016\/j.jns.2019.01.038_bb0140","doi-asserted-by":"crossref","first-page":"287843","DOI":"10.1155\/2015\/287843","article-title":"Transcranial magnetic stimulation to address mild cognitive impairment in the elderly: a randomized controlled study","volume":"2015","author":"Drumond Marra","year":"2015","journal-title":"Behav. Neurol."},{"issue":"5","key":"10.1016\/j.jns.2019.01.038_bb0145","first-page":"280","article-title":"Adjunctive treatment with high frequency repetitive transcranial magnetic stimulation for the behavioral and psychological symptoms of patients with Alzheimer's disease: a randomized, double-blind, sham-controlled study","volume":"27","author":"Wu","year":"2015","journal-title":"Shanghai Arch. Psychiatry"},{"issue":"1","key":"10.1016\/j.jns.2019.01.038_bb0150","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s13311-016-0487-6","article-title":"Transcranial magnetic stimulation for the assessment of neurodegenerative disease","volume":"14","author":"Vucic","year":"2017","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.jns.2019.01.038_bb0155","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.13598","article-title":"Transcranial magnetic stimulation (TMS) inhibits cortical dendrites","volume":"5","author":"Murphy","year":"2016","journal-title":"Elife"},{"issue":"8","key":"10.1016\/j.jns.2019.01.038_bb0160","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1016\/j.neurobiolaging.2015.04.016","article-title":"Effects of noninvasive brain stimulation on cognitive function in healthy aging and Alzheimer's disease: a systematic review and meta-analysis","volume":"36","author":"Hsu","year":"2015","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.jns.2019.01.038_bb0165","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.neuroimage.2013.06.007","article-title":"Enhancement of human cognitive performance using transcranial magnetic stimulation (TMS)","volume":"85","author":"Luber","year":"2014","journal-title":"NeuroImage"},{"issue":"4","key":"10.1016\/j.jns.2019.01.038_bb0170","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1001\/jamaneurol.2014.4380","article-title":"Effects of repetitive transcranial magnetic stimulation on motor symptoms in Parkinson's disease: a systematic review and meta-analysis","volume":"72","author":"Chou","year":"2015","journal-title":"JAMA Neurol."},{"issue":"6","key":"10.1016\/j.jns.2019.01.038_bb0180","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/ane.12223","article-title":"Transcranial magnetic stimulation (TMS)\/repetitive TMS in mild cognitive impairment and Alzheimer's disease","volume":"129","author":"Nardone","year":"2014","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.jns.2019.01.038_bb0185","first-page":"687909","article-title":"Effect of transcranial brain stimulation for the treatment of Alzheimer's disease: a review","volume":"2012","author":"Nardone","year":"2012","journal-title":"Int. J. Alzheimer's Dis."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X19300383?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X19300383?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T19:44:10Z","timestamp":1565207050000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X19300383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":36,"alternative-id":["S0022510X19300383"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2019.01.038","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of repetitive transcranial magnetic stimulation (rTMS) in the treatment of cognitive impairment in patients with Alzheimer's disease: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2019.01.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}