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Agents Chemother."},{"issue":"4","key":"10.1016\/j.jns.2019.01.050_bb0405","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/01.inf.0000059765.92623.70","article-title":"Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis","volume":"22","author":"Abzug","year":"2003","journal-title":"Pediatr. Infect. Dis. J."},{"issue":"12","key":"10.1016\/j.jns.2019.01.050_bb0410","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1086\/375069","article-title":"Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials","volume":"36","author":"Hayden","year":"2003","journal-title":"Clin. Infect. 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