{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T14:53:43Z","timestamp":1763564023755,"version":"3.40.5"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Liaoning BaiQianWan Talents Program of China","award":["2014921036"],"award-info":[{"award-number":["2014921036"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jns-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.jns.2019.02.037","type":"journal-article","created":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T11:50:56Z","timestamp":1551268256000},"page":"199-206","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Comparative efficacy and safety of multiple antiplatelet therapies for secondary prevention of ischemic stroke or transient ischemic attack: A network meta-analysis"],"prefix":"10.1016","volume":"399","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0902-9072","authenticated-orcid":false,"given":"Rong-wu","family":"Xiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruo-bing","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-yu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-yi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-chun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-sheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang-qing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong-yi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting-yan","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2012","key":"10.1016\/j.jns.2019.02.037_bb0005","first-page":"2095","article-title":"Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study","volume":"380","author":"Lozano","year":"2010","journal-title":"Lancet."},{"issue":"2012","key":"10.1016\/j.jns.2019.02.037_bb0010","first-page":"2197","article-title":"Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study","volume":"380","author":"Murray","year":"2010","journal-title":"Lancet."},{"key":"10.1016\/j.jns.2019.02.037_bb0015","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1161\/STR.0000000000000024","article-title":"Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"45","author":"Kernan","year":"2014","journal-title":"Stroke."},{"key":"10.1016\/j.jns.2019.02.037_bb0020","doi-asserted-by":"crossref","first-page":"e601S","DOI":"10.1378\/chest.11-2302","article-title":"Antithrombotic and thrombolytic therapy for ischemic stroke: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141","author":"Lansberg","year":"2012","journal-title":"Chest."},{"issue":"2018","key":"10.1016\/j.jns.2019.02.037_bb0025","first-page":"e46","article-title":"Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"49","author":"Powers","year":"2018","journal-title":"Stroke."},{"key":"10.1016\/j.jns.2019.02.037_bb0030","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ."},{"key":"10.1016\/j.jns.2019.02.037_bb0035","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0140-6736(10)60903-8","article-title":"An international registry of systematic-review protocols","volume":"377","author":"Booth","year":"2011","journal-title":"Lancet."},{"key":"10.1016\/j.jns.2019.02.037_bb0045","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/asi.20317","article-title":"CiteSpace II: detecting and visualizing emerging trends and transient patterns in scientific literature","volume":"57","author":"Chen","year":"2006","journal-title":"J. Am. Soc. Inf. Sci. Technol."},{"year":"2015","series-title":"Meta-Analysis with R (Use-R!)","author":"Schwarzer","key":"10.1016\/j.jns.2019.02.037_bb0050"},{"key":"10.1016\/j.jns.2019.02.037_bb0055","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jclinepi.2010.03.016","article-title":"Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial","volume":"64","author":"Salanti","year":"2011","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.jns.2019.02.037_bb0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0076654","article-title":"Graphical tools for network meta-analysis in STATA","volume":"8","author":"Chaimani","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jns.2019.02.037_bb0065","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1056\/NEJMra071014","article-title":"Platelet activation and atherothrombosis","volume":"357","author":"Davi","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jns.2019.02.037_bb0070","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.thromres.2013.03.011","article-title":"Cilostazol for peripheral arterial disease could reduce stroke risk?","volume":"132","author":"Watson","year":"2013","journal-title":"Thromb. Res."},{"key":"10.1016\/j.jns.2019.02.037_bb0075","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.2147\/VHRM.S3160","article-title":"Safety and efficacy of cilostazol in the management of intermittent claudication","volume":"4","author":"Chi","year":"2008","journal-title":"Vasc. Health Risk Manag."},{"key":"10.1016\/j.jns.2019.02.037_bb0080","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.atherosclerosissup.2005.09.002","article-title":"Cilostazol: potential mechanism of action for antithrombotic effects accompanied by a low rate of bleeding","volume":"6","author":"Goto","year":"2005","journal-title":"Atheroscler. Suppl."},{"key":"10.1016\/j.jns.2019.02.037_bb0085","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S1474-4422(10)70198-8","article-title":"Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial","volume":"9","author":"Shinohara","year":"2010","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2019.02.037_bb0090","doi-asserted-by":"crossref","first-page":"328","DOI":"10.3109\/09537104.2013.827781","article-title":"Variability of on-treatment platelet reactivity in patients on clopidogrel","volume":"25","author":"Freynhofer","year":"2014","journal-title":"Platelets."},{"key":"10.1016\/j.jns.2019.02.037_bb0095","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1373\/clinchem.2012.198101","article-title":"Microfluidic assay of platelet deposition on collagen by perfusion of whole blood from healthy individuals taking aspirin","volume":"59","author":"Li","year":"2013","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jns.2019.02.037_bb0100","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJMoa060989","article-title":"Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events","volume":"354","author":"Bhatt","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jns.2019.02.037_bb0105","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1016\/S0140-6736(09)60503-1","article-title":"Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials","volume":"373","author":"Antithrombotic Trialists","year":"2009","journal-title":"Lancet."},{"key":"10.1016\/j.jns.2019.02.037_bb0110","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.324.7329.71","article-title":"Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients","volume":"324","author":"Antithrombotic Trialists C","year":"2002","journal-title":"BMJ."},{"key":"10.1016\/j.jns.2019.02.037_bb0115","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1161\/CIRCULATIONAHA.106.675991","article-title":"Variable platelet response to aspirin and clopidogrel in atherothrombotic disease","volume":"115","author":"Maree","year":"2007","journal-title":"Circulation."},{"key":"10.1016\/j.jns.2019.02.037_bb0120","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-009013","article-title":"Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis","volume":"6","author":"Niu","year":"2016","journal-title":"BMJ Open"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X1930108X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X1930108X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,23]],"date-time":"2019-03-23T04:53:13Z","timestamp":1553316793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X1930108X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":23,"alternative-id":["S0022510X1930108X"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2019.02.037","relation":{},"ISSN":["0022-510X"],"issn-type":[{"type":"print","value":"0022-510X"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative efficacy and safety of multiple antiplatelet therapies for secondary prevention of ischemic stroke or transient ischemic attack: A network meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2019.02.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}