{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:09:37Z","timestamp":1777039777123,"version":"3.51.4"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Universidad Esp\u00edritu Santo \u2013 Ecuador"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.jns.2019.05.019","type":"journal-article","created":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T23:52:25Z","timestamp":1558482745000},"page":"133-135","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Neuroimaging signatures of cerebral small vessel disease and risk of falls in stroke-free older adults living in rural Ecuador. The Atahualpa Project"],"prefix":"10.1016","volume":"402","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1917-8805","authenticated-orcid":false,"given":"Oscar H.","family":"Del Brutto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos D.","family":"Peinado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robertino M.","family":"Mera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor J.","family":"Del Brutto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.","family":"Sedler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2019.05.019_bb0005","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jsr.2016.05.001","article-title":"The direct costs of fatal and non-fatal falls among older adults \u2013 United States","volume":"58","author":"Burns","year":"2016","journal-title":"J. Saf. Res."},{"key":"10.1016\/j.jns.2019.05.019_bb0010","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jamda.2015.03.023","article-title":"White matter lesions (leukoaraiosis): a major cause of falls","volume":"16","author":"Morley","year":"2015","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"10.1016\/j.jns.2019.05.019_bb0015","first-page":"173","article-title":"The correlation between white matter hyperintensity and balance disorders and fall risk: an observational, prospective cohort study","volume":"2","author":"Shen","year":"2016","journal-title":"Chronic Dis. Transl. Med."},{"key":"10.1016\/j.jns.2019.05.019_bb0020","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/ijs.12279","article-title":"Sub-cortical infarcts and the risk of falls in older people: combined results of TASCOG and Sydney MAS studies","volume":"55","author":"Callisaya","year":"2014","journal-title":"Int. J. Stroke"},{"key":"10.1016\/j.jns.2019.05.019_bb0025","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/ijs.12030","article-title":"Door-to-door survey of cardiovascular health, stroke, and ischemic heart disease in rural coastal Ecuador \u2013 the Atahualpa Project: methodology and operational definitions","volume":"9","author":"Del Brutto","year":"2014","journal-title":"Int. J. Stroke"},{"key":"10.1016\/j.jns.2019.05.019_bb0030","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/ijs.12417","article-title":"White matter hyperintensities of presumed vascular origin: a population-based study in rural Ecuador (the Atahualpa project)","volume":"10","author":"Del Brutto","year":"2015","journal-title":"Int. J. Stroke"},{"key":"10.1016\/j.jns.2019.05.019_bb0035","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1159\/000081050","article-title":"Impact of age-related cerebral white matter changes on the transition to disability: the LADIS study: rationale, design and methodology","volume":"24","author":"Pantoni","year":"2005","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.jns.2019.05.019_bb0040","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1212\/WNL.0b013e3181c34a7d","article-title":"The microbleed anatomical rating scale (MARS): reliability of a tool to map brain microbleeds","volume":"73","author":"Gregoire","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2019.05.019_bb0045","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S1474-4422(13)70124-8","article-title":"Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration","volume":"12","author":"Wardlaw","year":"2013","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2019.05.019_bb0050","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1161\/STROKEAHA.109.564914","article-title":"Enlarged perivascular spaces on MRI are a feature of cerebral small vessel disease","volume":"41","author":"Doubal","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2019.05.019_bb0055","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1111\/jgs.14439","article-title":"Fall risk assessment predicts fall-related injury, hip fracture, and head injury in older adults","volume":"64","author":"Nilsson","year":"2016","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.jns.2019.05.019_bb0060","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.jphys.2018.05.005","article-title":"Downton fall risk index during hospitalization is associated with fall-related injuries after discharge: a longitudinal observational study","volume":"64","author":"Mojtaba","year":"2018","journal-title":"J. Physiother."},{"key":"10.1016\/j.jns.2019.05.019_bb0065","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1161\/CIRCULATIONAHA.109.192703","article-title":"American Heart Association strategic planning task force and statistics committee. Defining and setting national goals for cardiovascular health promotion. The American Heart Association's strategic impact goal through 2020 and beyond","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jns.2019.05.019_bb0070","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/ijs.12102","article-title":"Stroke in rural coastal Ecuador: a community-based survey","volume":"9","author":"Del Brutto","year":"2014","journal-title":"Int. J. Stroke"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X19302357?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X19302357?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:47:18Z","timestamp":1758383238000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X19302357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":14,"alternative-id":["S0022510X19302357"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2019.05.019","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroimaging signatures of cerebral small vessel disease and risk of falls in stroke-free older adults living in rural Ecuador. The Atahualpa Project","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2019.05.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}