{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:18:02Z","timestamp":1767849482600,"version":"3.49.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.jns.2019.116545","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T12:16:09Z","timestamp":1571660169000},"page":"116545","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Discriminating chorea-acanthocytosis from Huntington's disease with single-case voxel-based morphometry analysis"],"prefix":"10.1016","volume":"408","author":[{"given":"Fumio","family":"Suzuki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9305-7131","authenticated-orcid":false,"given":"Noriko","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8873-0822","authenticated-orcid":false,"given":"Miho","family":"Ota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuhiko","family":"Sugiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Shigemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emiko","family":"Morimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noritaka","family":"Wakasugi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinori","family":"Futamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8454-6155","authenticated-orcid":false,"given":"Kenjiro","family":"Ono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Sano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1180-2629","authenticated-orcid":false,"given":"Osamu","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2019.116545_bb0005","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/88821","article-title":"A conserved sorting-associated protein is mutant in chorea-acanthocytosis","volume":"28","author":"Rampoldi","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.jns.2019.116545_bb0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/88825","article-title":"The gene encoding a newly discovered protein, chorein, is mutated in chorea-acanthocytosis","volume":"28","author":"Ueno","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.jns.2019.116545_bb0015","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s00109-002-0349-z","article-title":"Clinical features and molecular bases of neuroacanthocytosis","volume":"80","author":"Rampoldi","year":"2002","journal-title":"J. Mol. Med. (Berl.)"},{"key":"10.1016\/j.jns.2019.116545_bb0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.14802\/jmd.15009","article-title":"Untangling the thorns: advances in the neuroacanthocytosis syndromes","volume":"8","author":"Walker","year":"2015","journal-title":"J. Mov. Disord."},{"key":"10.1016\/j.jns.2019.116545_bb0025","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","article-title":"A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes","volume":"72","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.jns.2019.116545_bb0030","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/ene.13413","article-title":"Huntington's disease: a clinical review","volume":"25","author":"McColgan","year":"2018","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.jns.2019.116545_bb0035","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1167\/iovs.04-0539","article-title":"Eye Movements in chorea-acanthocytosis","volume":"46","author":"Gradstein","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jns.2019.116545_bb0040","first-page":"25","article-title":"Magnetic resonance imaging in Huntington disease","volume":"7","author":"Simmons","year":"1986","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jns.2019.116545_bb0045","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1002\/mds.21046","article-title":"Head of the caudate nucleus is most vulnerable in chorea-acanthocytosis: a voxel-based morphometry study","volume":"21","author":"Henkel","year":"2006","journal-title":"Mov Disord"},{"key":"10.1016\/j.jns.2019.116545_bb0050","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1007\/s00702-008-0094-8","article-title":"Automatic striatal volumetry allows for identification of patients with chorea-acanthocytosis at single subject level","volume":"115","author":"Huppertz","year":"2008","journal-title":"J Neural Transm (Vienna)"},{"key":"10.1016\/j.jns.2019.116545_bb0055","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.pscychresns.2010.10.006","article-title":"Shape alterations in the striatum in chorea-acanthocytosis","volume":"192","author":"Walterfang","year":"2011","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jns.2019.116545_bb0060","doi-asserted-by":"crossref","first-page":"539","DOI":"10.3174\/ajnr.A1390","article-title":"Voxel-based morphometry in individual patients: a pilot study in early Huntington disease","volume":"30","author":"M\u0171hlau","year":"2009","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jns.2019.116545_bb0065","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.3174\/ajnr.A2128","article-title":"Regional distribution and clinical correlates of white matter structural damage in Huntington disease: a tract-based spatial statistics study","volume":"31","author":"Della Nave","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jns.2019.116545_bb0070","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1097\/01.rct.0000284390.53202.2e","article-title":"Combining functional and structural brain magnetic resonance imaging in Huntington disease","volume":"31","author":"Gavazzi","year":"2007","journal-title":"J Comput Assist Tomogr"},{"key":"10.1016\/j.jns.2019.116545_bb0075","first-page":"213","article-title":"Topography of cerebral atrophy in early Huntington\u2019s disease: a voxel based morphometric MRI study","volume":"75","author":"Kassubek","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jns.2019.116545_bb0080","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.neulet.2005.03.038","article-title":"Voxel-based morphometry to discriminate early Alzheimer's disease from controls","volume":"382","author":"Hirata","year":"2005","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jns.2019.116545_bb0085","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s00234-013-1138-9","article-title":"Discrimination of dementia with Lewy bodies from Alzheimer's disease using voxel-based morphometry of white matter by statistical parametric mapping 8 plus diffeomorphic anatomic registration through exponentiated lie algebra","volume":"55","author":"Nakatsuka","year":"2013","journal-title":"Neuroradiology"},{"key":"10.1016\/j.jns.2019.116545_bb0090","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.nicl.2014.02.009","article-title":"The feasibility of white matter volume reduction analysis using SPM8 plus DARTEL for the diagnosis of patients with clinically diagnosed corticobasal syndrome and Richardson's syndrome","volume":"7","author":"Sakurai","year":"2015","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.jns.2019.116545_bb0095","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.3174\/ajnr.A2935","article-title":"Automatic voxel-based morphometry of structural MRI by SPM8 plus diffeomorphic anatomic registration through exponentiated lie algebra improves the diagnosis of probable Alzheimer disease","volume":"33","author":"Matsuda","year":"2012","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jns.2019.116545_bb0100","first-page":"29","article-title":"Voxel-based morphometry of brain MRI in normal aging and Alzheimer's disease","volume":"4","author":"Matsuda","year":"2013","journal-title":"Aging Dis"},{"key":"10.1016\/j.jns.2019.116545_bb0105","doi-asserted-by":"crossref","first-page":"755","DOI":"10.14336\/AD.2017.0818","article-title":"Voxel-based specific regional analysis system for Alzheimer's disease (VSRAD) on 3-tesla normal database: diagnostic accuracy in two independent cohorts with early Alzheimer's disease","volume":"9","author":"Sone","year":"2018","journal-title":"Aging Dis"},{"key":"10.1016\/j.jns.2019.116545_bb0110","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.neuroimage.2007.07.007","article-title":"A fast diffeomorphic image registration algorithm","volume":"38","author":"Ashburner","year":"2007","journal-title":"Neuroimage"},{"key":"10.1016\/j.jns.2019.116545_bb0115","doi-asserted-by":"crossref","DOI":"10.1212\/NXG.0000000000000332","article-title":"Novel pathogenic VPS13A gene mutations in Japanese patients with chorea-acanthocytosis","volume":"5","author":"Nishida","year":"2019","journal-title":"Neurol. Genet."},{"key":"10.1016\/j.jns.2019.116545_bb0120","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000338216","article-title":"Globus pallidus interna deep brain stimulation improves chorea and functional status in a patient with chorea-acanthocytosis","volume":"90","author":"Shin","year":"2012","journal-title":"Stereotact Funct Neurosurg"},{"key":"10.1016\/j.jns.2019.116545_bb0125","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/sj.ejhg.5200866","article-title":"Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis","volume":"10","author":"Dobson-Stone","year":"2002","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.jns.2019.116545_bb0130","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1002\/ajmg.b.31206","article-title":"Novel pathogenic mutations and copy number variations in the VPS13A gene in patients with chorea-acanthocytosis","volume":"156B","author":"Tomiyasu","year":"2011","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.jns.2019.116545_bb0135","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s00401-008-0403-1","article-title":"A neuropathological study of autosomal-dominant chorea-acanthocytosis with a mutation of VPS13A","volume":"117","author":"Ishida","year":"2009","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.jns.2019.116545_bb0140","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00401-013-1241-3","article-title":"Neuropathological findings in chorea-acanthocytosis: new insights into mechanisms underlying parkinsonism and seizures","volume":"127","author":"Connolly","year":"2014","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.jns.2019.116545_bb0145","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/nan.12403","article-title":"Hippocampal sclerosis and mesial temporal lobe epilepsy in chorea-acanthocytosis: a case with clinical, pathologic and genetic evaluation","volume":"43","author":"Mente","year":"2017","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.jns.2019.116545_bb0150","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.parkreldis.2018.01.009","article-title":"Subcortical neurodegeneration in chorea: similarities and differences between chorea-acanthocytosis and Huntington's disease","volume":"49","author":"Liu","year":"2018","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.jns.2019.116545_bb0155","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/nan.12495","article-title":"Pathoarchitectonics of the cerebral cortex in chorea- acanthocytosis and Huntington's disease","volume":"45","author":"Liu","year":"2019","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.jns.2019.116545_bb0160","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2967\/jnumed.110.081281","article-title":"Observation of glucose metabolism in the thalamic nuclei by fusion PET\/MRI","volume":"52","author":"Cho","year":"2011","journal-title":"J Nucl Med"},{"key":"10.1016\/j.jns.2019.116545_bb0165","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1002\/hbm.24227","article-title":"Thalamic white matter in multiple sclerosis: a combined diffusion-tensor imaging and quantitative susceptibility mapping study","volume":"39","author":"Bergsland","year":"2018","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.jns.2019.116545_bb0170","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.neuroimage.2009.03.044","article-title":"In vivo evidence for the selective subcortical degeneration in Huntington's disease","volume":"46","author":"Douaud","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.jns.2019.116545_bb0175","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.nicl.2013.03.017","article-title":"In vivo evaluation of gray and white matter volume loss in the parkinsonian variant of multiple system atrophy using SPM8 plus DARTEL for VBM","volume":"5","author":"Shigemoto","year":"2013","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.jns.2019.116545_bb0180","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/00005072-198511000-00003","article-title":"Neuropathological classification of Huntington's disease","volume":"44","author":"Vonsattel","year":"1985","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.jns.2019.116545_bb0185","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/00005072-198809000-00003","article-title":"Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease","volume":"47","author":"de la Monte","year":"1988","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.jns.2019.116545_bb0190","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/BF00867584","article-title":"McLeod syndrome: a distinct form of neuroacanthocytosis. Report of two cases and literature review with emphasis on neuromuscular manifestations","volume":"239","author":"Witt","year":"1992","journal-title":"J Neurol"},{"key":"10.1016\/j.jns.2019.116545_bb0195","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1212\/01.WNL.0000085866.68470.6D","article-title":"Huntington's disease-like 2 can present as chorea-acanthocytosis","volume":"61","author":"Walker","year":"2003","journal-title":"Neurology"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X19323093?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X19323093?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:48:25Z","timestamp":1758383305000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X19323093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":39,"alternative-id":["S0022510X19323093"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2019.116545","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Discriminating chorea-acanthocytosis from Huntington's disease with single-case voxel-based morphometry analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2019.116545","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116545"}}