{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T07:37:29Z","timestamp":1773041849483,"version":"3.50.1"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["18H02743"],"award-info":[{"award-number":["18H02743"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.jns.2022.120524","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T11:01:32Z","timestamp":1670842892000},"page":"120524","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Diagnostic utility of susceptibility-weighted imaging in amyotrophic lateral sclerosis"],"prefix":"10.1016","volume":"444","author":[{"given":"Masaaki","family":"Yasui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinsoo","family":"Koh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Sakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Hiwatani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Ishiguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidefumi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2022.120524_bb0005","doi-asserted-by":"crossref","first-page":"17071","DOI":"10.1038\/nrdp.2017.71","article-title":"Amyotrophic lateral sclerosis","volume":"3","author":"Hardiman","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"8","key":"10.1016\/j.jns.2022.120524_bb0010","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1016\/j.clinph.2020.04.012","article-title":"Diagnostic criteria for amyotrophic lateral sclerosis from El Escorial to Gold Coast","volume":"131","author":"Johnsen","year":"2020","journal-title":"Clin. Neurophysiol."},{"issue":"8","key":"10.1016\/j.jns.2022.120524_bb0015","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9082538","article-title":"Diagnostic and prognostic value of conventional brain MRI in the clinical work-up of patients with amyotrophic lateral sclerosis","volume":"9","author":"Rizzo","year":"2020","journal-title":"J. Clin. Med."},{"issue":"18","key":"10.1016\/j.jns.2022.120524_bb0020","doi-asserted-by":"crossref","first-page":"e2552","DOI":"10.1212\/WNL.0000000000010731","article-title":"Structural and functional brain connectome in motor neuron diseases: a multicenter MRI study","volume":"95","author":"Basaia","year":"2020","journal-title":"Neurology"},{"issue":"5","key":"10.1016\/j.jns.2022.120524_bb0025","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1002\/jmri.27530","article-title":"Magnetic resonance Iron imaging in amyotrophic lateral sclerosis","volume":"55","author":"Bhattarai","year":"2021","journal-title":"J. Magn. Reson. Imaging."},{"key":"10.1016\/j.jns.2022.120524_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2019.116440","article-title":"The motor band sign in ALS: presentations and frequencies in a consecutive series of ALS patients","volume":"406","author":"Roeben","year":"2019","journal-title":"J. Neurol. Sci."},{"issue":"3","key":"10.1016\/j.jns.2022.120524_bb0035","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1002\/mrm.20198","article-title":"Susceptibility weighted imaging (SWI)","volume":"52","author":"Haacke","year":"2004","journal-title":"Magn. Reson. Med."},{"issue":"4","key":"10.1016\/j.jns.2022.120524_bb0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0035241","article-title":"Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology","volume":"7","author":"Kwan","year":"2012","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jns.2022.120524_bb0045","first-page":"445","article-title":"Concentrations of zinc and iron in the brains of Guamanian patients with amyotrophic lateral sclerosis and parkinsonism-dementia","volume":"14","author":"Yasui","year":"1993","journal-title":"Neurotoxicology"},{"issue":"3","key":"10.1016\/j.jns.2022.120524_bb0050","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/jon.12841","article-title":"Susceptibility-weighted imaging in neurodegenerative disorders: a review","volume":"31","author":"Sotoudeh","year":"2021","journal-title":"J. Neuroimaging."},{"issue":"3","key":"10.1016\/j.jns.2022.120524_bb0055","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/jon.12127","article-title":"Usefulness of SWI for the detection of Iron in the motor cortex in amyotrophic lateral sclerosis","volume":"25","author":"Adachi","year":"2015","journal-title":"J. Neuroimaging"},{"issue":"3","key":"10.1016\/j.jns.2022.120524_bb0060","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1007\/s00415-017-8728-0","article-title":"Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study","volume":"265","author":"Endo","year":"2018","journal-title":"J. Neurol."},{"key":"10.1016\/j.jns.2022.120524_bb0065","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.clinimag.2020.12.018","article-title":"A specific biomarker for amyotrophic lateral sclerosis: quantitative susceptibility mapping","volume":"75","author":"Dean","year":"2021","journal-title":"Clin. Imaging"},{"issue":"4","key":"10.1016\/j.jns.2022.120524_bb0070","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1148\/rg.210054","article-title":"Quantitative susceptibility mapping: basic methods and clinical applications","volume":"42","author":"Harada","year":"2022","journal-title":"Radiographics"},{"issue":"2","key":"10.1016\/j.jns.2022.120524_bb0075","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1212\/01.wnl.0000194316.91908.8a","article-title":"Progression rate of ALSFRS-R at time of diagnosis predicts survival time in ALS","volume":"66","author":"Kimura","year":"2006","journal-title":"Neurology"},{"issue":"18","key":"10.1016\/j.jns.2022.120524_bb0080","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1212\/WNL.0b013e3181fb84d1","article-title":"Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis","volume":"75","author":"Filippini","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2022.120524_bb0085","series-title":"The Cerebral Cortex of Man","author":"Penfield","year":"1950"},{"key":"10.1016\/j.jns.2022.120524_bb0090","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3389\/fnins.2019.00180","article-title":"Iron in neurodegeneration - cause or consequence?","volume":"13","author":"Ndayisaba","year":"2019","journal-title":"Front. Neurosci."},{"issue":"5","key":"10.1016\/j.jns.2022.120524_bb0095","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.jns.2022.120524_bb0100","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0361-9230(03)00179-5","article-title":"Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals","volume":"61","author":"Carri","year":"2003","journal-title":"Brain Res. Bull."},{"issue":"3","key":"10.1016\/j.jns.2022.120524_bb0105","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1523\/JNEUROSCI.5443-08.2009","article-title":"Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis","volume":"29","author":"Jeong","year":"2009","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.jns.2022.120524_bb0110","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1159\/000323469","article-title":"Prevention of motor neuron degeneration by novel iron chelators in SOD1(G93A) transgenic mice of amyotrophic lateral sclerosis","volume":"8","author":"Wang","year":"2011","journal-title":"Neurodegener. Dis."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X22003860?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X22003860?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T16:02:12Z","timestamp":1758384132000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X22003860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":22,"alternative-id":["S0022510X22003860"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2022.120524","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic utility of susceptibility-weighted imaging in amyotrophic lateral sclerosis","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2022.120524","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"120524"}}