{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T18:37:26Z","timestamp":1773167846427,"version":"3.50.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.jns.2022.120536","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T19:55:17Z","timestamp":1672257317000},"page":"120536","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["MDS-UDPRS-III in the diagnosis of idiopathic Normal Pressure Hydrocephalus and identification of candidates for Ventriculo-Peritoneal Shunting surgery. Results from a retrospective large cohort of patients"],"prefix":"10.1016","volume":"445","author":[{"given":"Enrico","family":"Belgrado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Tereshko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Tuniz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Lettieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Bagatto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Fabbro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Piccolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Luigi","family":"Gigli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miran","family":"Skrap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariarosaria","family":"Valente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2022.120536_bb0005","doi-asserted-by":"crossref","DOI":"10.1227\/01.NEU.0000168185.29659.C5","article-title":"Diagnosing idiopathic normal-pressure hydrocephalus","volume":"57","author":"Relkin","year":"2005","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jns.2022.120536_bb0010","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1007\/s00415-017-8598-5","article-title":"Parkinsonian symptoms in normal pressure hydrocephalus: a population-based study","volume":"264","author":"Molde","year":"2017","journal-title":"J. Neurol."},{"key":"10.1016\/j.jns.2022.120536_bb0015","doi-asserted-by":"crossref","DOI":"10.1007\/s10072-022-06119-3","article-title":"Parkinsonism in idiopathic normal pressure hydrocephalus: is it time for defining a clinical tetrad?","author":"Mostile","year":"2022","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.jns.2022.120536_bb0020","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3988\/jcn.2016.12.4.452","article-title":"Asymmetric and upper body parkinsonism in patients with idiopathic Normal-pressure hydrocephalus","volume":"12","author":"Kang","year":"2016","journal-title":"J Clin Neurol"},{"key":"10.1016\/j.jns.2022.120536_bb0025","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1007\/s00415-020-10267-x","article-title":"iNPH with parkinsonism: response to lumbar CSF drainage and ventriculoperitoneal shunting","volume":"268","author":"Mostile","year":"2021","journal-title":"J. Neurol."},{"key":"10.1016\/j.jns.2022.120536_bb0030","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1600-0404.2012.01677.x","article-title":"A new scale for assessment of severity and outcome in iNPH","volume":"126","author":"Hellstr\u00f6m","year":"2012","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.jns.2022.120536_bb0035","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000111149","article-title":"Validation of grading scale for evaluating symptoms of idiopathic normal-pressure hydrocephalus","volume":"25","author":"Kubo","year":"2008","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.jns.2022.120536_bb0040","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1212\/WNL.0000000000002193","article-title":"Practice guideline: idiopathic normal pressure hydrocephalus: response to shunting and predictors of response: report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology","volume":"85","author":"Halperin","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2022.120536_bb0045","doi-asserted-by":"crossref","first-page":"63","DOI":"10.2176\/nmc.st.2020-0292","article-title":"Guidelines for Management of Idiopathic Normal Pressure Hydrocephalus (third edition): endorsed by the Japanese Society of Normal Pressure Hydrocephalus","volume":"61","author":"Nakajima","year":"2021","journal-title":"Neurol. Med. Chir. (Tokyo)"},{"key":"10.1016\/j.jns.2022.120536_bb0050","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1002\/mds.22340","article-title":"Movement Disorder Society-sponsored revision of the unified Parkinson\u2019s disease rating scale (MDS-UPDRS): scale presentation and clinimetric testing results","volume":"23","author":"Goetz","year":"2008","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2022.120536_bb0055","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1532-5415.1991.tb01616.x","article-title":"The timed \u201cup & go\u201d: a test of basic functional mobility for frail elderly persons","volume":"39","author":"Podsiadlo","year":"1991","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.jns.2022.120536_bb0060","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/1743-0003-10-117","article-title":"Dual-task related gait changes after CSF tapping: a new way to identify idiopathic normal pressure hydrocephalus","volume":"10","author":"Allali","year":"2013","journal-title":"J Neuroeng Rehabil"},{"key":"10.1016\/j.jns.2022.120536_bb0065","doi-asserted-by":"crossref","first-page":"733","DOI":"10.2522\/ptj.20070214","article-title":"Test-retest reliability and minimal detectable change on balance and ambulation tests, the 36-item short-form health survey, and the unified Parkinson disease rating scale in people with parkinsonism","volume":"88","author":"Steffen","year":"2008","journal-title":"Phys. Ther."},{"key":"10.1016\/j.jns.2022.120536_bb0070","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s10072-005-0443-4","article-title":"The frontal assessment battery (FAB): normative values in an Italian population sample","volume":"26","author":"Appollonio","year":"2005","journal-title":"Neurol Sci."},{"key":"10.1016\/j.jns.2022.120536_bb0075","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1056\/NEJM198812293192604","article-title":"Risk factors for falls among elderly persons living in the community","volume":"319","author":"Tinetti","year":"1988","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jns.2022.120536_bb0080","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1136\/jnnp-2012-303314","article-title":"The European iNPH multicentre study on the predictive values of resistance to CSF outflow and the CSF tap test in patients with idiopathic normal pressure hydrocephalus","volume":"84","author":"Wikkels\u00f8","year":"2013","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jns.2022.120536_bb0085","doi-asserted-by":"crossref","first-page":"e2861","DOI":"10.1212\/WNL.0000000000012064","article-title":"Clinical outcome and striatal dopaminergic function after shunt surgery in patients with idiopathic Normal pressure hydrocephalus","volume":"96","author":"Todisco","year":"2021","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2022.120536_bb0090","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S1474-4422(17)30157-6","article-title":"Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches","volume":"16","author":"Boxer","year":"2017","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2022.120536_bb0095","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1212\/WNL.0000000000004058","article-title":"Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the DLB consortium","volume":"89","author":"McKeith","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2022.120536_bb0100","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/mds.20083","article-title":"Clinicopathological investigation of vascular parkinsonism, including clinical criteria for diagnosis","volume":"19","author":"Zijlmans","year":"2004","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2022.120536_bb0105","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1017\/S1041610211001220","article-title":"Revised NIA-AA criteria for the diagnosis of Alzheimer\u2019s disease: a step forward but not yet ready for widespread clinical use","volume":"23","author":"Frisoni","year":"2011","journal-title":"Int Psychogeriatrics"},{"key":"10.1016\/j.jns.2022.120536_bb0110","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.jalz.2018.02.018","article-title":"NIA-AA research framework: toward a biological definition of Alzheimer\u2019s disease","volume":"14","author":"Jack","year":"2018","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.jns.2022.120536_bb0115","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1212\/WNL.40.10.1529","article-title":"Variable expression of Parkinson\u2019s disease: a base-line analysis of the DATATOP cohort. The Parkinson Study Group","volume":"40","author":"Jankovic","year":"1990","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2022.120536_bb0120","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/3-211-30714-1_75","article-title":"Outcome predictors for normal-pressure hydrocephalus","volume":"96","author":"Kiefer","year":"2006","journal-title":"Acta Neurochir Suppl"},{"key":"10.1016\/j.jns.2022.120536_bb0125","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1007\/s00701-017-3301-2","article-title":"Finger tapping and verbal fluency post-tap test improvement in INPH: its value in differential diagnosis and shunt-treatment outcomes prognosis","volume":"159","author":"Liouta","year":"2017","journal-title":"Acta Neurochir."},{"key":"10.1016\/j.jns.2022.120536_bb0130","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1093\/brain\/awn232","article-title":"Idiopathic normal pressure hydrocephalus: increased supplementary motor activity accounts for improvement after CSF drainage","volume":"131","author":"Lenfeldt","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.jns.2022.120536_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinbiomech.2022.105757","article-title":"Dynamic gait stability in patients with idiopathic normal pressure hydrocephalus with high and low fall-risk","volume":"99","author":"Nikaido","year":"2022","journal-title":"Clin Biomech (Bristol, Avon)"},{"issue":"Suppl","key":"10.1016\/j.jns.2022.120536_bb0140","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00415-008-4004-7","article-title":"Substrates for normal gait and pathophysiology of gait disturbances with respect to the basal ganglia dysfunction","volume":"255","author":"Takakusaki","year":"2008","journal-title":"J. Neurol."},{"key":"10.1016\/j.jns.2022.120536_bb0145","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12987-017-0072-3","article-title":"The role of perfusion and diffusion MRI in the assessment of patients affected by probable idiopathic normal pressure hydrocephalus. A cohort-prospective preliminary study","volume":"14","author":"Tuniz","year":"2017","journal-title":"Fluids Barriers CNS"},{"key":"10.1016\/j.jns.2022.120536_bb0150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0240327","article-title":"MRI diffusion and perfusion alterations in the mesencephalon and pons as markers of disease and symptom reversibility in idiopathic normal pressure hydrocephalus","volume":"15","author":"Agerskov","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jns.2022.120536_bb0155","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1016\/j.wneu.2021.09.071","article-title":"The role of simultaneous medical conditions in idiopathic Normal pressure hydrocephalus","volume":"157","author":"Valsecchi","year":"2022","journal-title":"World Neurosurg"},{"key":"10.1016\/j.jns.2022.120536_bb0160","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1002\/mds.870130310","article-title":"Gait variability and basal ganglia disorders: stride-to-stride variations of gait cycle timing in Parkinson\u2019s disease and Huntington\u2019s disease","volume":"13","author":"Hausdorff","year":"1998","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2022.120536_bb0165","first-page":"95","article-title":"Neural control of walking in people with parkinsonism","volume":"31","author":"Peterson","year":"2016","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.jns.2022.120536_bb0170","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2022.866313","article-title":"Pathophysiological mechanisms underlying idiopathic Normal pressure hydrocephalus: a review of recent insights","volume":"14","author":"Bonney","year":"2022","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.jns.2022.120536_bb0175","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0166-2236(89)90074-X","article-title":"The functional anatomy of basal ganglia disorders","volume":"12","author":"Albin","year":"1989","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.jns.2022.120536_bb0180","doi-asserted-by":"crossref","first-page":"6148","DOI":"10.1038\/s41598-020-63238-7","article-title":"Indication of Thalamo-cortical circuit dysfunction in idiopathic Normal pressure hydrocephalus: a tensor imaging study","volume":"10","author":"Eleftheriou","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jns.2022.120536_bb0185","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/mds.1270","article-title":"Vascular parkinsonism: clinical correlates predicting motor improvement after lumbar puncture","volume":"17","author":"Ondo","year":"2002","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2022.120536_bb0190","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/ane.12419","article-title":"Cerebrospinal fluid diversion in patients with enlarged Virchow-Robin spaces without ventriculomegaly","volume":"133","author":"Scollato","year":"2016","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.jns.2022.120536_bb0195","doi-asserted-by":"crossref","first-page":"147ra111","DOI":"10.1126\/scitranslmed.3003748","article-title":"A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid \u03b2","volume":"4","author":"Iliff","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jns.2022.120536_bb0200","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1212\/WNL.55.4.523","article-title":"Hemispheric asymmetries of limb-kinetic apraxia: a loss of deftness","volume":"55","author":"Heilman","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2022.120536_bb0205","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1002\/mds.28251","article-title":"Gaps, controversies, and proposed roadmap for research in Normal pressure hydrocephalus","volume":"35","author":"Fasano","year":"2020","journal-title":"Mov. Disord."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X22003987?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X22003987?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T16:00:01Z","timestamp":1758384001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X22003987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":41,"alternative-id":["S0022510X22003987"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2022.120536","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MDS-UDPRS-III in the diagnosis of idiopathic Normal Pressure Hydrocephalus and identification of candidates for Ventriculo-Peritoneal Shunting surgery. Results from a retrospective large cohort of patients","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2022.120536","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"120536"}}