{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T23:09:28Z","timestamp":1787699368023,"version":"build-2784847793"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T00:00:00Z","timestamp":1714867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002996","name":"Nederlandse Hartstichting","doi-asserted-by":"publisher","award":["2018-28"],"award-info":[{"award-number":["2018-28"]}],"id":[{"id":"10.13039\/501100002996","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002996","name":"Nederlandse Hartstichting","doi-asserted-by":"publisher","award":["CVON 2012-06"],"award-info":[{"award-number":["CVON 2012-06"]}],"id":[{"id":"10.13039\/501100002996","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.jns.2024.123026","type":"journal-article","created":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T23:54:05Z","timestamp":1714866845000},"page":"123026","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients"],"prefix":"10.1016","volume":"461","author":[{"given":"Naomi L.P.","family":"Starmans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J.","family":"Wolters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna E.","family":"Leeuwis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther E.","family":"Bron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"de Bresser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Peter","family":"Brunner-La Rocca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Staals","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majon","family":"Muller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert Jan","family":"Biessels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Jaap","family":"Kappelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2024.123026_bb0005","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.2147\/NDT.S182123","article-title":"Orthostatic hypotension and dementia incidence: links and implications","volume":"15","author":"Robertson","year":"2019","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.jns.2024.123026_bb0010","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10286-011-0119-5","article-title":"Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome","volume":"21","author":"Freeman","year":"2011","journal-title":"Clin. Auton. Res."},{"key":"10.1016\/j.jns.2024.123026_bb0015","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1161\/HYPERTENSIONAHA.120.14993","article-title":"Blood pressure and risks of cognitive impairment and dementia: a systematic review and meta-analysis of 209 prospective studies","volume":"76","author":"Ou","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2024.123026_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12875-020-01313-8","article-title":"Prevalence of postural hypotension in primary, community and institutional care: a systematic review and meta-analysis","volume":"22","author":"McDonagh","year":"2021","journal-title":"BMC Fam. Pract."},{"key":"10.1016\/j.jns.2024.123026_bb0025","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1161\/HYPERTENSIONAHA.118.10609","article-title":"Orthostatic hypotension in the first minute after standing up: what is the clinical relevance and do symptoms matter?","volume":"71","author":"Van Wijnen","year":"2018","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2024.123026_bb0030","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S1474-4422(22)00169-7","article-title":"Diagnosis and treatment of orthostatic hypotension","volume":"21","author":"Wieling","year":"2022","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2024.123026_bb0035","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1161\/HYPERTENSIONAHA.117.09048","article-title":"Orthostatic hypotension and risk of incident dementia: results from a 12-year follow-up of the Three-City study cohort","volume":"70","author":"Cremer","year":"2017","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2024.123026_bb0040","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.2147\/CIA.S72316","article-title":"Orthostatic intolerance predicts mild cognitive impairment: incidence of mild cognitive impairment and dementia from the Swedish general population cohort Good Aging in Sk\u00e5ne","volume":"9","author":"Elmst\u00e5hl","year":"2014","journal-title":"Clin. Interv. Aging"},{"key":"10.1016\/j.jns.2024.123026_bb0045","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s10654-017-0228-0","article-title":"Longitudinal and postural changes of blood pressure predict dementia: the Malm\u00f6 Preventive Project","volume":"32","author":"Holm","year":"2017","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.jns.2024.123026_bb0050","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1161\/HYPERTENSIONAHA.121.17454","article-title":"From normal cognition to cognitive impairment and dementia: impact of orthostatic hypotension","volume":"78","author":"Xia","year":"2021","journal-title":"Hypertension"},{"key":"10.1016\/j.jns.2024.123026_bb0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002143","article-title":"Orthostatic hypotension and the long-term risk of dementia: a population-based study","volume":"13","author":"Wolters","year":"2016","journal-title":"PLoS Med."},{"key":"10.1016\/j.jns.2024.123026_bb0060","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.008976","article-title":"Is baseline orthostatic hypotension associated with a decline in global cognitive performance at 4-year follow-up? Data from TILDA (The Irish Longitudinal Study on Ageing)","volume":"7","author":"McNicholas","year":"2018","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.jns.2024.123026_bb0065","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3233\/JAD-190402","article-title":"Orthostatic hypotension: an important risk factor for clinical progression to mild cognitive impairment or dementia. The Amsterdam Dementia Cohort","volume":"71","author":"Kleipool","year":"2019","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.jns.2024.123026_bb0070","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3390\/geriatrics6020050","article-title":"Eight orthostatic haemodynamic patterns in the Irish Longitudinal Study on Ageing (TILDA): stability and clinical associations after 4 years","volume":"6","author":"Moloney","year":"2021","journal-title":"Geriatrics (Basel)"},{"key":"10.1016\/j.jns.2024.123026_bb0075","doi-asserted-by":"crossref","first-page":"e1941","DOI":"10.1212\/WNL.0000000000010456","article-title":"Orthostatic hypotension, dizziness, neurology outcomes, and death in older adults","volume":"95","author":"Juraschek","year":"2020","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2024.123026_bb0080","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/gerona\/gly061","article-title":"Orthostatic hypotension and cognitive function: cross-sectional results from the ELSA-Brasil Study","volume":"74","author":"Suemoto","year":"2019","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.jns.2024.123026_bb0085","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1161\/ATVBAHA.115.306768","article-title":"Cerebral vasoreactivity, apolipoprotein E, and the risk of dementia: a population-based study","volume":"36","author":"Wolters","year":"2016","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jns.2024.123026_bb0090","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1161\/STROKEAHA.112.663716","article-title":"Cerebrovascular reserve and stroke risk in patients with carotid stenosis or occlusion: a systematic review and meta-analysis","volume":"43","author":"Gupta","year":"2012","journal-title":"Stroke"},{"key":"10.1016\/j.jns.2024.123026_bb0095","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000480738","article-title":"The missing link in the pathophysiology of vascular cognitive impairment: Design of the Heart-Brain Study","volume":"7","author":"Hooghiemstra","year":"2017","journal-title":"Cerebrovasc Dis Extra"},{"key":"10.1016\/j.jns.2024.123026_bb0100","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jns.2024.123026_bb0105","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1017\/S1355617705050344","article-title":"Rey\u2019s verbal learning test: normative data for 1855 healthy participants aged 24-81 years and the influence of age, sex, education, and mode of presentation","volume":"11","author":"Van der Elst","year":"2005","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"10.1016\/j.jns.2024.123026_bb0110","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1136\/jnnp.73.2.126","article-title":"Visual association test to detect early dementia of the Alzheimer type","volume":"73","author":"Lindeboom","year":"2002","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jns.2024.123026_bb0115","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1017\/S1355617706060115","article-title":"Normative data for the Animal, Profession and Letter M Naming verbal fluency tests for Dutch speaking participants and the effects of age, education, and sex","volume":"12","author":"Van Der Elst","year":"2006","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"10.1016\/j.jns.2024.123026_bb0120","series-title":"Handleiding Groninger Intelligentie Test (Manual Groninger Intelligence Test)","author":"Luteijn","year":"1983"},{"key":"10.1016\/j.jns.2024.123026_bb0125","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1037\/h0044509","article-title":"The relation of the trail making test to organic brain damage","volume":"19","author":"Reitan","year":"1955","journal-title":"J. Consult. Psychol."},{"key":"10.1016\/j.jns.2024.123026_bb0130","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1177\/1073191105283427","article-title":"The Stroop Color-Word Test: influence of age, sex, and education; and normative data for a large sample across the adult age range","volume":"13","author":"Van Der Elst","year":"2006","journal-title":"Assessment"},{"key":"10.1016\/j.jns.2024.123026_bb0135","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1080\/13803390591004428","article-title":"The Letter Digit Substitution Test: Normative data for 1,858 healthy participants aged 24-81 from the Maastricht Aging Study (MAAS): influence of age, education, and sex","volume":"28","author":"Van Der Elst","year":"2006","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"10.1016\/j.jns.2024.123026_bb0140","first-page":"63","article-title":"Cijferreeksen en Knox blokken als concentratietests voor ouderen [Digit series and Knox cubes as concentration tests for elderly subjects]","volume":"25","author":"Lindeboom","year":"1994","journal-title":"Tijdschr. Gerontol. Geriatr."},{"key":"10.1016\/j.jns.2024.123026_bb0145","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S1474-4422(13)70124-8","article-title":"Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration","volume":"12","author":"Wardlaw","year":"2013","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2024.123026_bb0150","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.neuroimage.2009.01.011","article-title":"White matter lesion extension to automatic brain tissue segmentation on MRI","volume":"45","author":"De Boer","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.jns.2024.123026_bb0155","article-title":"Capturing postural blood pressure dynamics with near-infrared spectroscopy-measured cerebral oxygenation","author":"Klop","year":"2023","journal-title":"Geroscience"},{"key":"10.1016\/j.jns.2024.123026_bb0160","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.006206","article-title":"Inter-relations of orthostatic blood pressure change, aortic stiffness, and brain structure and function in young adults","volume":"6","author":"Cooper","year":"2017","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.jns.2024.123026_bb0165","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.3233\/JAD-161228","article-title":"Cognitive status, gray matter atrophy, and lower orthostatic blood pressure in older adults","volume":"57","author":"O\u2019Hare","year":"2017","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.jns.2024.123026_bb0170","doi-asserted-by":"crossref","first-page":"e814","DOI":"10.1212\/WNL.0000000000012342","article-title":"Association of orthostatic hypotension with cerebral atrophy in patients with Lewy Body disorders","volume":"97","author":"Pilotto","year":"2021","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2024.123026_bb0175","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1192\/bjp.bp.110.090423","article-title":"Relationship of orthostatic blood pressure to white matter hyperintensities and subcortical volumes in late-life depression","volume":"199","author":"Colloby","year":"2011","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jns.2024.123026_bb0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052196","article-title":"Relationship between orthostatic hypotension and white matter hyperintensity load in older patients with mild dementia","volume":"7","author":"Soennesyn","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.jns.2024.123026_bb0185","first-page":"2410","article-title":"Association of white mater lesions with orthostatic hypotension","volume":"14","author":"Wei","year":"2022","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.jns.2024.123026_bb0190","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1093\/gerona\/glt171","article-title":"Orthostatic hypotension is associated with lower cognitive performance in adults aged 50 plus with supine hypertension","volume":"69","author":"Frewen","year":"2014","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X24001618?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X24001618?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T17:29:52Z","timestamp":1736184592000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X24001618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":38,"alternative-id":["S0022510X24001618"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2024.123026","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2024.123026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"123026"}}