{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:09:45Z","timestamp":1789578585760,"version":"build-2803163510"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"am","delay-in-days":353,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.jns.2024.123056","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T16:38:48Z","timestamp":1715963928000},"page":"123056","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Enlarged perivascular spaces and their association with motor, cognition, MRI markers and cerebrovascular risk factors in male fragile X premutation carriers"],"prefix":"10.1016","volume":"461","author":[{"given":"Andrea","family":"Elias-Mas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Yi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laia","family":"Rodr\u00edguez-Revenga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoungmi","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flora","family":"Tassone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hessl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan M.","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randi","family":"Hagerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2024.123056_bb0005","doi-asserted-by":"crossref","first-page":"4391","DOI":"10.3390\/ijms21124391","article-title":"Fragile X-associated tremor\/Ataxia syndrome (FXTAS): pathophysiology and clinical implications","volume":"21","author":"Cabal-Herrera","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jns.2024.123056_bb0010","first-page":"1757","article-title":"Fragile X premutation carriers: characteristic MR imaging findings of adult male patients with progressive cerebellar and cognitive dysfunction","volume":"23","author":"Brunberg","year":"2002","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"10.1016\/j.jns.2024.123056_bb0015","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neurobiolaging.2017.03.018","article-title":"Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation","volume":"55","author":"Wang","year":"2017","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.jns.2024.123056_bb0020","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/brain\/awh683","article-title":"Neuropathology of fragile X-associated tremor\/ataxia syndrome (FXTAS)","volume":"129","author":"Greco","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.jns.2024.123056_bb0025","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1002\/mds.28559","article-title":"Cerebral microbleeds in fragile X\u2013associated tremor\/ataxia syndrome","volume":"36","author":"Salcedo-Arellano","year":"2021","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2024.123056_bb0030","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2018.00531","article-title":"The Spectrum of neurological and white matter changes and premutation status categories of older male carriers of the FMR1 alleles are linked to genetic (CGG and FMR1 mRNA) and cellular stress (AMPK) markers","volume":"9","author":"Loesch","year":"2018","journal-title":"Front. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0035","article-title":"Clinical and molecular correlates of abnormal changes in the cerebellum and globus pallidus in fragile X premutation","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0040","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1212\/01.wnl.0000281692.98200.f5","article-title":"FMR1 CGG repeat length predicts motor dysfunction in premutation carriers","volume":"70","author":"Leehey","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2024.123056_bb0045","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1212\/01.wnl.0000239837.57475.3a","article-title":"Molecular and imaging correlates of the fragile X-associated tremor\/ataxia syndrome","volume":"67","author":"Cohen","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2024.123056_bb0050","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1002\/ana.20542","article-title":"Magnetic resonance imaging study in older fragile X premutation male carriers","volume":"58","author":"Loesch","year":"2005","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0055","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/ajmg.b.30482","article-title":"CGG repeat length correlates with age of onset of motor signs of the fragile X-associated tremor\/ataxia syndrome (FXTAS)","volume":"144B","author":"Tassone","year":"2007","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0060","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1037\/0894-4105.22.1.48","article-title":"Cognitive profile of fragile X premutation carriers with and without fragile X-associated tremor\/ataxia syndrome","volume":"22","author":"Grigsby","year":"2008","journal-title":"Neuropsychology"},{"key":"10.1016\/j.jns.2024.123056_bb0065","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s12311-016-0763-3","article-title":"Consensus paper: towards a systems-level view of cerebellar function: the interplay between cerebellum, basal ganglia, and cortex","volume":"16","author":"Caligiore","year":"2017","journal-title":"Cerebellum"},{"key":"10.1016\/j.jns.2024.123056_bb0070","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1002\/mds.25473","article-title":"A multimodal imaging analysis of subcortical gray matter in fragile X premutation carriers","volume":"28","author":"Wang","year":"2013","journal-title":"Mov. Disord."},{"key":"10.1016\/j.jns.2024.123056_bb0075","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/gbb.12204","article-title":"Preliminary evidence of an effect of cerebellar volume on postural sway in FMR1 premutation males","volume":"14","author":"Birch","year":"2015","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.jns.2024.123056_bb0080","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1136\/jnnp-2016-313937","article-title":"Selective subcortical contributions to gait impairments in males with the FMR1 premutation","volume":"88","author":"Birch","year":"2017","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jns.2024.123056_bb0085","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1001\/jamaneurol.2013.2934","article-title":"Fragile X-associated tremor\/ataxia syndrome: influence of the FMR1 gene on motor fiber tracts in males with normal and premutation alleles","volume":"70","author":"Wang","year":"2013","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0090","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1007\/s11682-018-9928-7","article-title":"Reduced caudate volume and cognitive slowing in men at risk of fragile X-associated tremor ataxia syndrome","volume":"13","author":"Cvejic","year":"2019","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.jns.2024.123056_bb0095","doi-asserted-by":"crossref","first-page":"e107","DOI":"10.1212\/WNL.0000000000201349","article-title":"Determinants of perivascular spaces in the general population","volume":"100","author":"Evans","year":"2023","journal-title":"Neurology"},{"issue":"370","key":"10.1016\/j.jns.2024.123056_bb0100","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1126\/science.abb8739","article-title":"Glymphatic failure as a final common pathway to dementia","volume":"1979","author":"Nedergaard","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.jns.2024.123056_bb0105","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/S1474-4422(15)00221-5","article-title":"Implications of the discovery of brain lymphatic pathways","volume":"14","author":"Iliff","year":"2015","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0110","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1159\/000375153","article-title":"Cerebral perivascular spaces visible on magnetic resonance imaging: development of a qualitative rating scale and its observer reliability","volume":"39","author":"Potter","year":"2015","journal-title":"Cerebrovasc. Dis."},{"key":"10.1016\/j.jns.2024.123056_bb0115","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1016\/j.neurobiolaging.2015.06.024","article-title":"Total MRI load of cerebral small vessel disease and cognitive ability in older people","volume":"36","author":"Staals","year":"2015","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.jns.2024.123056_bb0120","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1177\/1747493019830321","article-title":"Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: a systematic review and meta-analysis","volume":"14","author":"Francis","year":"2019","journal-title":"Int. J. Stroke"},{"key":"10.1016\/j.jns.2024.123056_bb0125","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2020.00715","article-title":"The relationship between enlarged perivascular spaces and cognitive function: a Meta-analysis of observational studies","volume":"11","author":"Jie","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jns.2024.123056_bb0130","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/s41582-020-0312-z","article-title":"Perivascular spaces in the brain: anatomy, physiology and pathology","volume":"16","author":"Wardlaw","year":"2020","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0135","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1007\/s00234-021-02718-7","article-title":"Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology","volume":"63","author":"Gouveia-Freitas","year":"2021","journal-title":"Neuroradiology"},{"key":"10.1016\/j.jns.2024.123056_bb0140","doi-asserted-by":"crossref","first-page":"5446","DOI":"10.1007\/s00330-022-08649-y","article-title":"MRI-visible enlarged perivascular spaces: imaging marker to predict cognitive impairment in older chronic insomnia patients","volume":"32","author":"Wang","year":"2022","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.jns.2024.123056_bb0145","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1093\/brain\/awaa443","article-title":"Sleep deprivation impairs molecular clearance from the human brain","volume":"144","author":"Eide","year":"2021","journal-title":"Brain"},{"key":"10.1016\/j.jns.2024.123056_bb0150","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1002\/ajmg.b.31237","article-title":"Sleep apnea in fragile X premutation carriers with and without FXTAS","volume":"156","author":"Hamlin","year":"2011","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0155","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1002\/ajmg.a.35323","article-title":"Hypertension in FMR1 premutation males with and without fragile X-associated tremor\/ataxia syndrome (FXTAS)","volume":"158A","author":"Hamlin","year":"2012","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.jns.2024.123056_bb0160","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1212\/WNL.0b013e318271f7ff","article-title":"FXTAS: new insights and the need for revised diagnostic criteria","volume":"79","author":"Apartis","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2024.123056_bb0165","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1866-1955-6-31","article-title":"Emerging topics in FXTAS","volume":"6","author":"Hall","year":"2014","journal-title":"J. Neurodev. Disord."},{"key":"10.1016\/j.jns.2024.123056_bb0170","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1002\/mdc3.13084","article-title":"Women with fragile X\u2013associated tremor\/ataxia syndrome","volume":"7","author":"Schneider","year":"2020","journal-title":"Mov Disord Clin Pract."},{"key":"10.1016\/j.jns.2024.123056_bb0175","doi-asserted-by":"crossref","first-page":"87","DOI":"10.4088\/JCP.v67n0112","article-title":"Psychiatric phenotype of the fragile X-associated tremor\/ataxia syndrome (FXTAS) in males","volume":"67","author":"Bacalman","year":"2006","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jns.2024.123056_bb0180","series-title":"Wechsler Abbreviated Scale of Intelligence--Second Edition (WASI-II)","author":"Wechsler","year":"2011"},{"key":"10.1016\/j.jns.2024.123056_bb0185","series-title":"Wechsler Adult Intelligence Scale--Fourth Edition (WAIS-IV)","author":"Wechsler","year":"2008"},{"key":"10.1016\/j.jns.2024.123056_bb0190","series-title":"Wechsler Adult Intelligence Scale--Third Edition (WAIS-III)","author":"Wechsler","year":"1997"},{"key":"10.1016\/j.jns.2024.123056_bb0195","doi-asserted-by":"crossref","DOI":"10.1001\/archneur.65.7.963","article-title":"Detecting dementia with the Mini-mental state examination in highly educated individuals","volume":"65","author":"O\u2019Bryant","year":"2008","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0200","doi-asserted-by":"crossref","first-page":"883","DOI":"10.2466\/pms.1992.74.3.883","article-title":"Reliabilities, norms and factor structure of the behavioral Dyscontrol scale","volume":"74","author":"Grigsby","year":"1992","journal-title":"Percept. Mot. Skills"},{"key":"10.1016\/j.jns.2024.123056_bb0205","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1136\/jmedgenet-2013-102021","article-title":"CGG allele size somatic mosaicism and methylation in FMR1 premutation alleles","volume":"51","author":"Pretto","year":"2014","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0210","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1373\/clinchem.2009.136101","article-title":"A novel FMR1 PCR method for the routine detection of low abundance expanded alleles and full mutations in fragile X syndrome","volume":"56","author":"Filipovic-Sadic","year":"2010","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jns.2024.123056_bb0215","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2353\/jmoldx.2008.070073","article-title":"A rapid polymerase chain reaction-based screening method for identification of all expanded alleles of the fragile X (FMR1) gene in newborn and high-risk populations","volume":"10","author":"Tassone","year":"2008","journal-title":"J. Mol. Diagn."},{"key":"10.1016\/j.jns.2024.123056_bb0220","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/(SICI)1096-8628(19990528)84:3<250::AID-AJMG17>3.0.CO;2-4","article-title":"FMRP expression as a potential prognostic indicator in fragile X syndrome","volume":"84","author":"Tassone","year":"1999","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0225","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1086\/302720","article-title":"Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in the fragile-X syndrome","volume":"66","author":"Tassone","year":"2000","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0230","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.889884","article-title":"Topological relationships between perivascular spaces and progression of white matter hyperintensities: a pilot study in a sample of the Lothian birth cohort 1936","volume":"13","author":"Barnes","year":"2022","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0235","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1177\/0271678X211002279","article-title":"Deep white matter hyperintensity is associated with the dilation of perivascular space","volume":"41","author":"Huang","year":"2021","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.jns.2024.123056_bb0240","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1001\/jamaneurol.2017.1397","article-title":"Large perivascular spaces visible on magnetic resonance imaging, cerebral small vessel disease progression, and risk of dementia","volume":"74","author":"Ding","year":"2017","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0245","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/S1474-4422(19)30079-1","article-title":"Small vessel disease: mechanisms and clinical implications","volume":"18","author":"Wardlaw","year":"2019","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0250","doi-asserted-by":"crossref","first-page":"9171","DOI":"10.3390\/ijms22179171","article-title":"Brain atrophy and white matter damage linked to peripheral bioenergetic deficits in the neurodegenerative disease FXTAS","volume":"22","author":"Wang","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jns.2024.123056_bb0255","author":"R: The R Project for Statistical Computing"},{"key":"10.1016\/j.jns.2024.123056_bb0260","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.neuroimage.2004.06.018","article-title":"A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume","volume":"23","author":"Buckner","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.jns.2024.123056_bb0265","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc. B. Methodol."},{"key":"10.1016\/j.jns.2024.123056_bb0270","article-title":"Brain atrophy correlates with severe enlarged perivascular spaces in basal ganglia among lacunar stroke patients","volume":"11","author":"Zhang","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jns.2024.123056_bb0275","series-title":"Alzheimer\u2019s & Dementia: Translational Research & Clinical Interventions","first-page":"107","article-title":"White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): knowledge gaps and opportunities","volume":"5","author":"Alber","year":"2019"},{"key":"10.1016\/j.jns.2024.123056_bb0280","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1002\/cbin.11039","article-title":"FMRP regulates endothelial cell proliferation and angiogenesis via the miR-181a-CaM-CaMKII pathway","volume":"42","author":"Zhao","year":"2018","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.jns.2024.123056_bb0285","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1136\/hrt.61.3.289","article-title":"Cardiac abnormalities in the fragile X syndrome","volume":"61","author":"Sreeram","year":"1989","journal-title":"Heart"},{"key":"10.1016\/j.jns.2024.123056_bb0290","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1542\/peds.91.4.714","article-title":"Cardiovascular abnormalities in children with fragile X syndrome","volume":"91","author":"Crabbe","year":"1993","journal-title":"Pediatrics"},{"key":"10.1016\/j.jns.2024.123056_bb0295","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1093\/hmg\/10.14.1449","article-title":"Reduced FMRP and increased FMR1 transcription is proportionally associated with CGG repeat number in intermediate-length and premutation carriers","volume":"10","author":"Kenneson","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0300","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0226811","article-title":"Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions","volume":"14","author":"Kim","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jns.2024.123056_bb0305","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.celrep.2013.02.004","article-title":"Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters MicroRNA processing in fragile X-associated tremor\/Ataxia syndrome","volume":"3","author":"Sellier","year":"2013","journal-title":"Cell Rep."},{"key":"10.1016\/j.jns.2024.123056_bb0310","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2015.00015","article-title":"Progressive cognitive impairment evolving to dementia parallels Parieto-occipital and temporal enlargement in idiopathic chronic hydrocephalus: a retrospective cohort study","volume":"6","author":"Missori","year":"2015","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jns.2024.123056_bb0315","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neurobiolaging.2019.09.009","article-title":"Interaction between ventricular expansion and structural changes in the corpus callosum and putamen in males with FMR1 normal and premutation alleles","volume":"86","author":"Wang","year":"2020","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.jns.2024.123056_bb0320","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.molmed.2019.11.008","article-title":"Glymphatic system impairment in Alzheimer\u2019s disease and idiopathic Normal pressure hydrocephalus","volume":"26","author":"Reeves","year":"2020","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.jns.2024.123056_bb0325","doi-asserted-by":"crossref","first-page":"E11","DOI":"10.3171\/2016.7.FOCUS16194","article-title":"Imaging normal pressure hydrocephalus: theories, techniques, and challenges","volume":"41","author":"Keong","year":"2016","journal-title":"Neurosurg. Focus."},{"key":"10.1016\/j.jns.2024.123056_bb0330","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1136\/jmg.2003.012518","article-title":"Intranuclear inclusions in neural cells with premutation alleles in fragile X associated tremor\/ataxia syndrome","volume":"41","author":"Tassone","year":"2004","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.jns.2024.123056_bb0335","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12987-021-00243-6","article-title":"Exploring mechanisms of ventricular enlargement in idiopathic normal pressure hydrocephalus: a role of cerebrospinal fluid dynamics and motile cilia","volume":"18","author":"Yamada","year":"2021","journal-title":"Fluids Barriers CNS."},{"key":"10.1016\/j.jns.2024.123056_bb0340","first-page":"2146","article-title":"Hyperintensity of the middle cerebellar peduncles on fluid-attenuated inversion recovery imaging: variation with age and implications for the diagnosis of multiple system atrophy","volume":"27","author":"Ngai","year":"2006","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"10.1016\/j.jns.2024.123056_bb0345","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jocn.2015.08.010","article-title":"Fragile X-associated tremor\/ataxia syndrome: an under-recognised cause of tremor and ataxia","volume":"23","author":"Kalus","year":"2016","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.jns.2024.123056_bb0350","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2147\/CIA.S404908","article-title":"Enlarged perivascular spaces and age-related clinical diseases","volume":"18","author":"Yang","year":"2023","journal-title":"Clin. Interv. Aging"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X24001916?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X24001916?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T17:31:05Z","timestamp":1736184665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X24001916"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":70,"alternative-id":["S0022510X24001916"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2024.123056","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enlarged perivascular spaces and their association with motor, cognition, MRI markers and cerebrovascular risk factors in male fragile X premutation carriers","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2024.123056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"123056"}}