{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:28:48Z","timestamp":1773221328115,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.jns.2024.123068","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T07:05:35Z","timestamp":1717139135000},"page":"123068","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["A novel tool for characterising upper limb function in progressive multiple sclerosis through kinematic assessment"],"prefix":"10.1016","volume":"462","author":[{"given":"Linford","family":"Fernandes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel O.","family":"Coats","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Mon-Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Awais","family":"Hafeez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Holt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen L.","family":"Ford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jns.2024.123068_bb0005","doi-asserted-by":"crossref","first-page":"146","DOI":"10.7224\/1537-2073.2012-053","article-title":"Natural history of multiple sclerosis symptoms","volume":"15","author":"Kister","year":"2013","journal-title":"Int J MS Care."},{"issue":"12","key":"10.1016\/j.jns.2024.123068_bb0010","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1177\/1352458514567553","article-title":"Unilateral and bilateral upper limb dysfunction at body functions, activity and participation levels in people with multiple sclerosis","volume":"21","author":"Bertoni","year":"2015","journal-title":"Mult. Scler."},{"key":"10.1016\/j.jns.2024.123068_bb0015","first-page":"15","article-title":"Employment of patients with multiple sclerosis: the influence of psychosocial-structural coping and context","volume":"8","author":"Vijayasingham","year":"2018","journal-title":"Degener Neurol Neuromuscul Dis."},{"key":"10.1016\/j.jns.2024.123068_bb0020","series-title":"The Nine-Hole Peg Test as a Manual Dexterity Performance Measure for Multiple Sclerosis","first-page":"711","volume":"vol. 23","author":"Feys","year":"2017"},{"issue":"1","key":"10.1016\/j.jns.2024.123068_bb0025","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2522\/ptj.20130588","article-title":"Associations of upper limb disability measures on different levels of the international classification of functioning, disability and health in people with multiple sclerosis","volume":"95","author":"Lamers","year":"2015","journal-title":"Phys. Ther."},{"issue":"12","key":"10.1016\/j.jns.2024.123068_bb0030","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1177\/1352458519876701","article-title":"Clinical outcome measures in SPMS trials: an analysis of the IMPACT and ASCEND original trial data sets","volume":"26","author":"Koch","year":"2020","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.jns.2024.123068_bb0035","series-title":"Quantitative Assessment Based on Kinematic Measures of Functional Impairments during Upper Extremity Movements: A Review","first-page":"719","volume":"vol. 29","author":"De Los","year":"2014"},{"issue":"2","key":"10.1016\/j.jns.2024.123068_bb0040","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s00415-012-6639-7","article-title":"Grasping multiple sclerosis: do quantitative motor assessments provide a link between structure and function?","volume":"260","author":"Reilmann","year":"2013","journal-title":"J. Neurol."},{"issue":"1","key":"10.1016\/j.jns.2024.123068_bb0045","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/1743-0003-11-170","article-title":"Intention tremor and deficits of sensory feedback control in multiple sclerosis: a pilot study","volume":"11","author":"Heenan","year":"2014","journal-title":"J. Neuroeng. Rehabil."},{"issue":"3","key":"10.1016\/j.jns.2024.123068_bb0050","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1109\/TNSRE.2012.2187462","article-title":"Robot training of upper limb in multiple sclerosis: comparing protocols with or withoutmanipulative task components","volume":"20","author":"Carpinella","year":"2012","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"issue":"1","key":"10.1016\/j.jns.2024.123068_bb0055","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1743-0003-11-67","article-title":"Quantitative assessment of upper limb motor function in multiple sclerosis using an instrumented action research arm test","volume":"11","author":"Carpinella","year":"2014","journal-title":"J. Neuroeng. Rehabil."},{"issue":"10","key":"10.1016\/j.jns.2024.123068_bb0060","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1016\/j.clinph.2008.06.011","article-title":"Hand function in multiple sclerosis: force coordination in manipulation tasks","volume":"119","author":"Krishnan","year":"2008","journal-title":"Clin. Neurophysiol."},{"issue":"10","key":"10.1016\/j.jns.2024.123068_bb0065","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.3389\/fneur.2019.01395","article-title":"Characterization of upper limb impairments at body function, activity, and participation in persons with multiple sclerosis by behavioral and EMG assessment: a cross-sectional study","volume":"14","author":"Val\u00e8","year":"2020","journal-title":"Front. Neurol."},{"issue":"2019","key":"10.1016\/j.jns.2024.123068_bb0070","first-page":"1","article-title":"Is there any relationship between upper and lower limb impairments in people with multiple sclerosis? A kinematic quantitative analysis","volume":"9","author":"Coghe","year":"2019","journal-title":"Mult. Scler. Int."},{"issue":"11","key":"10.1016\/j.jns.2024.123068_bb0075","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1001\/jamaneurol.2023.3331","article-title":"Harmonizing definitions for progression independent of relapse activity in multiple sclerosis: a systematic review","volume":"80","author":"M\u00fcller","year":"2023","journal-title":"JAMA Neurol."},{"issue":"2","key":"10.1016\/j.jns.2024.123068_bb0080","article-title":"Addressing the targeting range of the ABILHAND-56 in relapsing\u2013remitting multiple sclerosis: a mixed methods psychometric study","volume":"4","author":"Cleanthous","year":"2018","journal-title":"Mult Scler J Exp Transl Clin."},{"issue":"14","key":"10.1016\/j.jns.2024.123068_bb0085","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1177\/1352458518808197","article-title":"Development of the arm function in multiple sclerosis questionnaire-short form (AMSQ-SF): a static 10-item version","volume":"24","author":"Luijten","year":"2018","journal-title":"Mult. Scler. J."},{"issue":"26","key":"10.1016\/j.jns.2024.123068_bb0090","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.3109\/09638288.2015.1027005","article-title":"The arm function in multiple sclerosis questionnaire (AMSQ): development and validation of a new tool using IRT methods","volume":"37","author":"Mokkink","year":"2015","journal-title":"Disabil. Rehabil."},{"key":"10.1016\/j.jns.2024.123068_bb0095","first-page":"608491","article-title":"Deciphering Multiple Sclerosis Progression. Vol. 12, Frontiers in Neurology","author":"Meca-Lallana","year":"2021","journal-title":"Frontiers Media SA"},{"issue":"5","key":"10.1016\/j.jns.2024.123068_bb0100","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1177\/1352458517690824","article-title":"The nine-hole peg test as a manual dexterity performance measure for multiple sclerosis","volume":"23","author":"Feys","year":"2017","journal-title":"Mult. Scler."},{"issue":"1","key":"10.1016\/j.jns.2024.123068_bb0105","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF00231054","article-title":"Factors affecting higher-order movement planning: a kinematic analysis of human prehension","volume":"86","author":"Jakobson","year":"1991","journal-title":"Exp. Brain Res."},{"issue":"1\u20132","key":"10.1016\/j.jns.2024.123068_bb0110","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s00221-005-0083-1","article-title":"Grasping with the left and right hand: a kinematic study","volume":"168","author":"Grosskopf","year":"2006","journal-title":"Exp. Brain Res."},{"issue":"5","key":"10.1016\/j.jns.2024.123068_bb0115","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.acn.2007.04.008","article-title":"Reaction time: an alternative method for assessing the effects of multiple sclerosis on information processing speed","volume":"22","author":"Reicker","year":"2007","journal-title":"Arch. Clin. Neuropsychol."},{"issue":"3","key":"10.1016\/j.jns.2024.123068_bb0120","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.clineuro.2009.11.017","article-title":"Motor and cognitive slowing in multiple sclerosis: an attentional deficit?","volume":"112","author":"Stoquart-ElSankari","year":"2010","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.jns.2024.123068_bb0125","first-page":"408","article-title":"Rate of force development and relaxation scaling factors are highly sensitive to detect upper extremity motor impairments in multiple sclerosis","volume":"15","author":"Uygur","year":"2020","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.jns.2024.123068_bb0130","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1743-0003-11-67","article-title":"Quantitative assessment of upper limb motor function in Multiple Sclerosis using an instrumented Action Research Arm Test","volume":"11","author":"Carpinella","year":"2014","journal-title":"J Neuroeng Rehabil"},{"issue":"4","key":"10.1016\/j.jns.2024.123068_bb0135","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1177\/1545968307311103","article-title":"Preserved and impaired aspects of feed-forward grip force control after chronic somatosensory deafferentation","volume":"22","author":"Hermsd\u00f6rfer","year":"2008","journal-title":"Neurorehabil. Neural Repair"},{"issue":"9","key":"10.1016\/j.jns.2024.123068_bb0140","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1016\/j.clinph.2021.05.028","article-title":"Altered sensorimotor integration in multiple sclerosis: a combined neurophysiological and functional MRI study","volume":"132","author":"Gianni","year":"2021","journal-title":"Clin. Neurophysiol."},{"issue":"10","key":"10.1016\/j.jns.2024.123068_bb0145","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.1109\/TBME.2009.2026470","article-title":"Characterization of EMG patterns from proximal arm muscles during object- and orientation-specific grasps","volume":"56","author":"Martelloni","year":"2009","journal-title":"IEEE Trans. Biomed. Eng."},{"issue":"10","key":"10.1016\/j.jns.2024.123068_bb0150","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.3389\/fneur.2019.01395","article-title":"Characterization of upper limb impairments at body function, activity, and participation in persons with multiple sclerosis by behavioral and EMG assessment: a cross-sectional study","volume":"14","author":"Val\u00e8","year":"2020","journal-title":"Front. Neurol."},{"issue":"30","key":"10.1016\/j.jns.2024.123068_bb0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.msard.2019.01.043","article-title":"Clinical correlates of 9-hole peg test in a large population of people with multiple sclerosis","volume":"1","author":"Solaro","year":"2019","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"45","key":"10.1016\/j.jns.2024.123068_bb0160","doi-asserted-by":"crossref","first-page":"102422","DOI":"10.1016\/j.msard.2020.102422","article-title":"Nine hole peg test asymmetry in refining upper limb assessment in multiple sclerosis","volume":"1","author":"Solaro","year":"2020","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"359","key":"10.1016\/j.jns.2024.123068_bb0165","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.bbr.2018.11.005","article-title":"Asymmetry of brain excitability: a new biomarker that predicts objective and subjective symptoms in multiple sclerosis","volume":"1","author":"Chaves","year":"2019","journal-title":"Behav. Brain Res."},{"issue":"1\u20132","key":"10.1016\/j.jns.2024.123068_bb0170","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00221-005-0073-3","article-title":"Control of aperture closure during reach-to-grasp movements in parkinson\u2019s disease","volume":"168","author":"Rand","year":"2006","journal-title":"Exp. Brain Res."},{"issue":"11","key":"10.1016\/j.jns.2024.123068_bb0175","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1007\/s10072-020-04363-z","article-title":"Italian validation of the arm function in multiple sclerosis questionnaire (AMSQ)","volume":"41","author":"Tacchino","year":"2020","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.jns.2024.123068_bb0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/450420","article-title":"Impaired object handling during bimanual task performance in multiple sclerosis","volume":"2014","author":"Gorniak","year":"2014","journal-title":"Mult. Scler. Int."},{"issue":"10","key":"10.1016\/j.jns.2024.123068_bb0185","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1177\/1352458513475832","article-title":"Perceived and actual arm performance in multiple sclerosis: relationship with clinical tests according to hand dominance","volume":"19","author":"Lamers","year":"2013","journal-title":"Mult. Scler."},{"issue":"3","key":"10.1016\/j.jns.2024.123068_bb0190","article-title":"Goal-directed upper limb movement patterns and hand grip forces in multiple sclerosis","volume":"8","author":"Kanzler","year":"2022","journal-title":"Mult Scler J Exp Transl Clin."},{"key":"10.1016\/j.jns.2024.123068_bb0195","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.neubiorev.2008.05.021","article-title":"The impact of stroke on the performance of grasping: usefulness of kinetic and kinematic motion analysis","volume":"32","author":"Nowak","year":"2008","journal-title":"Neuroscience and Biobehavioral Reviews. Pergamon"},{"issue":"2","key":"10.1016\/j.jns.2024.123068_bb0200","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s10072-022-06456-3","article-title":"Change in upper limb function in people with multiple sclerosis treated with nabiximols: a quantitative kinematic pilot study","volume":"44","author":"Pau","year":"2023","journal-title":"Neurol Sci"},{"issue":"69","key":"10.1016\/j.jns.2024.123068_bb0205","doi-asserted-by":"crossref","first-page":"104455","DOI":"10.1016\/j.msard.2022.104455","article-title":"Effect of immersive virtual reality training on hand-to-mouth task performance in people with multiple sclerosis: a quantitative kinematic study","volume":"1","author":"Pau","year":"2023","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"2","key":"10.1016\/j.jns.2024.123068_bb0210","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s00221-015-4474-7","article-title":"Eye and hand movement strategies in older adults during a complex reaching task","volume":"234","author":"Coats","year":"2016","journal-title":"Exp. Brain Res."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X2400203X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X2400203X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T09:26:43Z","timestamp":1728034003000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X2400203X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":42,"alternative-id":["S0022510X2400203X"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2024.123068","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel tool for characterising upper limb function in progressive multiple sclerosis through kinematic assessment","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2024.123068","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"123068"}}