{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:33:16Z","timestamp":1791221596256,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jns.2024.123365","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T11:40:10Z","timestamp":1735040410000},"page":"123365","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["MRZ-reaction maybe influenced by immunization status and is not exclusive to multiple sclerosis"],"prefix":"10.1016","volume":"468","author":[{"given":"Mary Anitha","family":"D'Cunha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lekha","family":"Pandit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshatha","family":"Sudhir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jns.2024.123365_bb0005","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/BF00422934","article-title":"The diagnostic significance of antibody specificity indices in multiple sclerosis and herpes virus induced diseases of the nervous system","volume":"70","author":"Felgenhauer","year":"1992","journal-title":"Clin. Investig."},{"key":"10.1016\/j.jns.2024.123365_bb0010","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1177\/135245859800400304","article-title":"The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis","volume":"4","author":"Reiber","year":"1998","journal-title":"Mult. Scler."},{"key":"10.1016\/j.jns.2024.123365_bb0015","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00415-016-8360-4","article-title":"The MRZ reaction as a highly specific marker of multiple sclerosis: re-evaluation and structured review of the literature","volume":"264","author":"Jarius","year":"2017","journal-title":"J. Neurol."},{"key":"10.1016\/j.jns.2024.123365_bb0020","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1002\/ana.20890","article-title":"B lineage cells in the inflammatory central nervous system environment: migration, maintenance, local antibody production and therapeutic modulation","volume":"59","author":"Meinl","year":"2006","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jns.2024.123365_bb0025","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3389\/fneur.2014.00027","article-title":"Does disease-irrelevant intrathecal synthesis in multiple sclerosis make sense in the light of tertiary lymphoid organs?","volume":"5","author":"Bonnan","year":"2014","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jns.2024.123365_bb0030","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1600-0404.2006.00755.x","article-title":"Intrathecal polyspecific immune response to neurotropic viruses in multiple sclerosis: a comparative report from Cuban patients","volume":"115","author":"Robinson- Agramonte","year":"2007","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.jns.2024.123365_bb0035","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1136\/jnnp.2007.133330","article-title":"Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica","volume":"79","author":"Jarius","year":"2008","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jns.2024.123365_bb0040","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12987-015-0024-8","article-title":"The intrathecal, polyspecific antiviral immune response in neurosarcoidosis, acute disseminated encephalomyelitis and autoimmune encephalitis compared to multiple sclerosis in a tertiary hospital cohort","volume":"12","author":"Hottenrott","year":"2015","journal-title":"Fluids Barriers CNS"},{"key":"10.1016\/j.jns.2024.123365_bb0045","first-page":"587","article-title":"Polyspecific immune reaction in the central nervous system in autoimmune diseases with CNS involvement","volume":"88","author":"Graef","year":"1994","journal-title":"Z. Arztl. Fortbild."},{"key":"10.1016\/j.jns.2024.123365_bb0050","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1474-4422(17)30470-2","article-title":"Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria","volume":"17","author":"Thompson","year":"2018","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2024.123365_bb0055","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S1474-4422(22)00431-8","article-title":"Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: international MOGAD panel proposed criteria","volume":"22","author":"Banwell","year":"2023","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jns.2024.123365_bb0060","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1212\/WNL.0000000000001729","article-title":"International consensus diagnostic criteria for neuromyelitis optica spectrum disorders","volume":"85","author":"Wingerchuk","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.jns.2024.123365_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2021.577706","article-title":"Overcoming the challenges in diagnosis of AQP4-IgG positive neuromyelitis optica spectrum disorders in resource poor settings using an indigenized and cost effective cell based assay","volume":"360","author":"Pandit","year":"2021","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jns.2024.123365_bb0070","unstructured":"Pandit L, D'Cunha A, Malli C, Sudhir A. Comparison of live and fixed cell- based assay performance - implications in the diagnosis of MOGAD in a low- middle income country. Front. Immunol.; https:\/\/doi.org\/10.3389\/fimmu.2023.125265."},{"issue":"4","key":"10.1016\/j.jns.2024.123365_bb0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0124064","article-title":"Environmental factors related to Multiple sclerosis in Indian population","volume":"10","author":"Malli","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jns.2024.123365_bb0080","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1093\/clinchem\/37.7.1153","article-title":"Quantification of virus specific antibodies in cerebrospinal fluid and serum: sensitive and specific detection of antibody synthesis in brain","volume":"37","author":"Reiber","year":"1991","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jns.2024.123365_bb0085","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/ajim.22046","article-title":"Prevalence of measles, mumps, rubella, and varicella susceptibility among health science students in a university in India","volume":"56","author":"Arunkumar","year":"2013","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.jns.2024.123365_bb0090","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1016\/S0140-6736(15)01190-3","article-title":"Public funded immunization \u2013 key to varicella control in India","volume":"386","author":"Dehal","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.jns.2024.123365_bb0095","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1186\/s12974-020-01824-2","article-title":"Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: results from 163 lumbar punctures in 100 adult patients","volume":"17","author":"Jarius","year":"2020","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.jns.2024.123365_bb0100","doi-asserted-by":"crossref","DOI":"10.1212\/NXI.0000000000001086","article-title":"CSF findings in acute NMDAR and LGI1 antibody\u2013associated autoimmune encephalitis","volume":"8","author":"Durr","year":"2021","journal-title":"Neurol. Neuroimmunol. Neuroinflamm."},{"key":"10.1016\/j.jns.2024.123365_bb0105","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2014-209075","article-title":"Periventricular white matter lesion and incomplete MRZ reaction in a male patient with anti-N-methyl-D-aspartate receptor encephalitis presenting with dysphoric mania","author":"Ghar","year":"2015","journal-title":"BMJ Case Rep."},{"key":"10.1016\/j.jns.2024.123365_bb0110","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.msard.2016.12.009","article-title":"Antecedent anti-NMDA receptor encephalitis in two patients with multiple sclerosis","volume":"12","author":"Baheerathan","year":"2017","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.jns.2024.123365_bb0115","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1743-8454-2-3","article-title":"Expansion of antibody reactivity in the cerebrospinal fluid of multiple sclerosis patients \u2013 follow-up and clinical implications","volume":"2","author":"Petereit","year":"2005","journal-title":"Cerebrospinal Fluid Res."}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X2400501X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022510X2400501X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T20:59:26Z","timestamp":1736456366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022510X2400501X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":23,"alternative-id":["S0022510X2400501X"],"URL":"https:\/\/doi.org\/10.1016\/j.jns.2024.123365","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MRZ-reaction maybe influenced by immunization status and is not exclusive to multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jns.2024.123365","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"123365"}}