{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:44:44Z","timestamp":1793126684651,"version":"4.5.0"},"reference-count":236,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2006,7]]},"DOI":"10.1016\/j.jnutbio.2005.11.007","type":"journal-article","created":{"date-parts":[[2005,12,15]],"date-time":"2005-12-15T15:38:49Z","timestamp":1134661129000},"page":"429-445","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":220,"title":["The role of virgin olive oil components in the modulation of endothelial function"],"prefix":"10.1016","volume":"17","author":[{"given":"Javier S.","family":"Perona","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosana","family":"Cabello-Moruno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Ruiz-Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2005.11.007_bib1","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/S0140-6736(96)07492-2","article-title":"Alternative projections of mortality and disability by cause 1990\u20132020: Global Burden of Disease Study","volume":"349","author":"Murray","year":"1997","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.jnutbio.2005.11.007_bib2","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1161\/01.CIR.99.9.1132","article-title":"Epidemic of cardiovascular disease and stroke: the three main challenges","volume":"99","author":"Fuster","year":"1999","journal-title":"Circulation"},{"issue":"2 Suppl","key":"10.1016\/j.jnutbio.2005.11.007_bib3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/07315724.2001.10719021","article-title":"High-energy diets, fatty acids and endothelial cell function: implications for atherosclerosis","volume":"20","author":"Hennig","year":"2001","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib4","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1177\/1358836X0000500108","article-title":"The endothelium: a new target for therapy","volume":"5","author":"Cooke","year":"2000","journal-title":"Vasc Med"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib5","series-title":"The endothelial cell in health and disease","first-page":"75","year":"1995"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib6","first-page":"71","article-title":"Endothelial dysfunction and antioxidants","volume":"72","author":"Duvall","year":"2005","journal-title":"Mt Sinai J Med"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib7","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis \u2014 an inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib8","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/path.1711710311","article-title":"The expression of adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis","volume":"171","author":"Davies","year":"1993","journal-title":"J Pathol"},{"issue":"1\u20132","key":"10.1016\/j.jnutbio.2005.11.007_bib9","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0271-5317(00)00289-X","article-title":"Nutrition and endothelial cell function: implications in atherosclerosis","volume":"21","author":"Hennig","year":"2001","journal-title":"Nutr Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib10","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/clc.4960200505","article-title":"Coronary risk factors, endothelial function and atherosclerosis: a review","volume":"20","author":"Vogel","year":"1997","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib11","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1146\/annurev.ph.57.030195.004043","article-title":"Cell biology of atherosclerosis","volume":"57","author":"Ross","year":"1995","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1006\/jmcc.1998.0841","article-title":"Primary endothelial dysfunction: atherosclerosis","volume":"31","author":"Shimokawa","year":"1999","journal-title":"J Mol Cell Cardiol"},{"issue":"27","key":"10.1016\/j.jnutbio.2005.11.007_bib13","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1056\/NEJM199312303292706","article-title":"The l-arginine\u2013nitric oxide pathway","volume":"329","author":"Moncada","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib14","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1161\/01.CIR.94.7.1682","article-title":"Fluid flow inhibits endothelial adhesiveness: nitric oxide and transcriptional regulation of VCAM-1","volume":"94","author":"Tsao","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib15","doi-asserted-by":"crossref","first-page":"10J","DOI":"10.1016\/S0002-9149(00)01334-5","article-title":"Relation between endothelial dysfunction and the acute coronary syndrome: implications for therapy","volume":"86","author":"Kinlay","year":"2000","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib16","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1749-6632.2000.tb06318.x","article-title":"Endothelial dysfunction, hemodynamic forces, and atherogenesis","volume":"902","author":"Gimbrone","year":"2000","journal-title":"Ann N Y Acad Sci"},{"issue":"2A","key":"10.1016\/j.jnutbio.2005.11.007_bib17","doi-asserted-by":"crossref","first-page":"31E","DOI":"10.1016\/S0002-9149(01)01764-7","article-title":"Measurement of endothelial function by brachial artery flow-mediated vasodilation","volume":"88","author":"Vogel","year":"2001","journal-title":"Am J Cardiol"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib18","doi-asserted-by":"crossref","first-page":"H1","DOI":"10.1152\/ajpheart.2002.282.1.H1","article-title":"Flow-mediated dilatation in human circulation: diagnostic and therapeutic aspects","volume":"282","author":"Kelm","year":"2002","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib19","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/S0002-8703(03)00097-8","article-title":"Detection of endothelial dysfunction with brachial artery ultrasound scanning","volume":"145","author":"Faulx","year":"2003","journal-title":"Am Heart J"},{"issue":"6736","key":"10.1016\/j.jnutbio.2005.11.007_bib20","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/21224","article-title":"Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation","volume":"399","author":"Dimmeler","year":"1999","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib21","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1378\/chest.127.6.2254","article-title":"Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool?","volume":"127","author":"Moens","year":"2005","journal-title":"Chest"},{"issue":"7","key":"10.1016\/j.jnutbio.2005.11.007_bib22","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1016\/S0735-1097(99)00104-7","article-title":"Impaired brachial artery endothelial function is not predicted by elevated triglycerides","volume":"33","author":"Schnell","year":"1999","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib23","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0033-0620(98)80008-X","article-title":"Cholesterol, cholesterol lowering, and endothelial function","volume":"41","author":"Vogel","year":"1998","journal-title":"Prog Cardiovasc Dis"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib24","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/S0002-9149(96)00760-6","article-title":"Effect of a single high-fat meal on endothelial function in healthy subjects","volume":"79","author":"Vogel","year":"1997","journal-title":"Am J Cardiol"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib25","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1016\/S0735-1097(00)00896-2","article-title":"The postprandial effect of components of the Mediterranean diet on endothelial function","volume":"36","author":"Vogel","year":"2000","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib26","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s00418-004-0675-z","article-title":"Nitric oxide insufficiency and atherothrombosis","volume":"122","author":"Voetsch","year":"2004","journal-title":"Histochem Cell Biol"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib27","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1540\/jsmr.39.249","article-title":"The endothelium in health and disease \u2014 a target for therapeutic intervention","volume":"39","author":"Triggle","year":"2003","journal-title":"J Smooth Muscle Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib28","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1172\/JCI116491","article-title":"Hypercholesterolemia increases endothelial superoxide anion production","volume":"91","author":"Ohara","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib29","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/S0891-5849(02)01015-8","article-title":"Hypercholesterolemia promotes inflammation and microvascular dysfunction: role of nitric oxide and superoxide","volume":"33","author":"Stokes","year":"2002","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib30","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1161\/01.CIR.0000012748.58444.08","article-title":"Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase","volume":"105","author":"Guzik","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib31","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1159\/000174145","article-title":"Nitric oxide and renal autoregulation","volume":"20","author":"Just","year":"1997","journal-title":"Kidney Blood Press Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib32","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1161\/01.HYP.33.6.1353","article-title":"Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium","volume":"33","author":"Kerr","year":"1999","journal-title":"Hypertension"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib33","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1172\/JCI115549","article-title":"Inactivation of endothelial derived relaxing factor by oxidized lipoproteins","volume":"89","author":"Chin","year":"1992","journal-title":"J Clin Invest"},{"issue":"9","key":"10.1016\/j.jnutbio.2005.11.007_bib34","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1073\/pnas.84.9.2995","article-title":"Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte\/macrophages during atherogenesis","volume":"84","author":"Quinn","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib35","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/0002-9149(91)90274-O","article-title":"Effects of high-density lipoprotein on acetylcholine-induced coronary vasoreactivity","volume":"68","author":"Kuhn","year":"1991","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib36","first-page":"32","article-title":"Dyslipidemia in diabetes mellitus","volume":"25","author":"Verges","year":"1999","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib37","doi-asserted-by":"crossref","first-page":"22Q","DOI":"10.1016\/S0002-9149(98)00770-X","article-title":"Triglyceride as a risk factor for coronary artery disease","volume":"5","author":"Gotto","year":"1998","journal-title":"Am J Cardiol"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib38","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/00045415-200205000-00005","article-title":"Hypertriglyceridemia: a review beyond low-density lipoprotein","volume":"10","author":"Rapp","year":"2002","journal-title":"Cardiol Rev"},{"issue":"141 Suppl 1","key":"10.1016\/j.jnutbio.2005.11.007_bib39","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1016\/S0021-9150(98)00219-6","article-title":"Triglycerides are more important in atherosclerosis than epidemiology has suggested","author":"Durrington","year":"1998","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib40","doi-asserted-by":"crossref","first-page":"232S","DOI":"10.1093\/ajcn\/71.1.232S","article-title":"Effect of long-chain n-3 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism","volume":"71","author":"Roche","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib41","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1161\/01.ATV.18.5.723","article-title":"Soluble cell adhesion molecules in hypertriglyceridemia and potential significance on monocyte adhesion","volume":"18","author":"Abe","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib42","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1161\/01.ATV.12.11.1336","article-title":"Relation of triglyceride metabolism and cardiovascular disease","volume":"12","author":"Patsch","year":"1992","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib43","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1097\/00019501-199408000-00008","article-title":"Chylomicrons or their remnants penetrate rabbit thoracic aorta as efficiently as do smaller macromolecules, including low-density lipoprotein, high-density lipoprotein, and albumin","volume":"5","author":"Mamo","year":"1994","journal-title":"Coron Artery Dis"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib44","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S1388-1981(03)00042-8","article-title":"Chylomicron remnant induction of lipid accumulation in J774 macrophages is associated with up-regulation of triacylglycerol synthesis which is not dependent on oxidation of the particles","volume":"1631","author":"Napolitano","year":"2003","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib45","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1161\/01.ATV.1.1.38","article-title":"Transfer of plasma lipoprotein components and of plasma proteins into aortas of cholesterol-fed rabbits. Molecular size as a determinant of plasma lipoprotein influx","volume":"1","author":"Stender","year":"1981","journal-title":"Arteriosclerosis"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib46","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S0022-2275(20)38428-5","article-title":"Large lipoproteins are excluded from the arterial wall in diabetic cholesterol-fed rabbits","volume":"29","author":"Nordestgaard","year":"1988","journal-title":"J Lipid Res"},{"issue":"10","key":"10.1016\/j.jnutbio.2005.11.007_bib47","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1161\/01.ATV.19.10.2474","article-title":"Detection, quantification, and characterization of potentially atherogenic triglyceride-rich remnant lipoproteins","volume":"19","author":"Cohn","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib48","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1161\/01.ATV.4.5.489","article-title":"Exposure to free fatty acid increases the transfer of albumin across cultured endothelial monolayers","volume":"4","author":"Hennig","year":"1984","journal-title":"Arteriosclerosis"},{"issue":"2\u20133","key":"10.1016\/j.jnutbio.2005.11.007_bib49","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0021-9150(92)90027-E","article-title":"Disruption of endothelial barrier function by lipolytic remnants of triglyceride-rich lipoproteins","volume":"95","author":"Hennig","year":"1992","journal-title":"Atherosclerosis"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib50","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0021-9150(97)00291-8","article-title":"Remnants of chylomicron and very low density lipoprotein impair endothelium-dependent vasorelaxation","volume":"137","author":"Doi","year":"1998","journal-title":"Atherosclerosis"},{"issue":"25","key":"10.1016\/j.jnutbio.2005.11.007_bib51","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1161\/01.CIR.97.25.2519","article-title":"Association of remnant lipoprotein levels with impairment of endothelium-dependent vasomotor function in human coronary arteries","volume":"97","author":"Kugiyama","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib52","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1161\/01.ATV.18.1.20","article-title":"Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia","volume":"18","author":"Eriksson","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib53","doi-asserted-by":"crossref","first-page":"132","DOI":"10.5551\/jat.10.132","article-title":"Induction of atherosclerosis by human chylomicron remnants: a hypothesis","volume":"10","author":"Wilhelm","year":"2003","journal-title":"J Atheroscler Thromb"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib54","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0049-3848(00)00290-5","article-title":"Plasma level of triglyceride-rich lipoprotein remnants is closely associated with the activation of coagulation factor VII in patients with myocardial infarction","volume":"100","author":"Saigo","year":"2000","journal-title":"Thromb Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib55","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0008-6363(99)00150-9","article-title":"Lipids and the endothelium","volume":"43","author":"Dart","year":"1999","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib56","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1161\/01.CIR.102.6.670","article-title":"Remnant lipoproteins induce proatherothrombogenic molecules in endothelial cells through a redox-sensitive mechanism","volume":"102","author":"Doi","year":"2000","journal-title":"Circulation"},{"issue":"105 Suppl 2","key":"10.1016\/j.jnutbio.2005.11.007_bib57","first-page":"35","article-title":"Chylomicrons induce E-selectin and VCAM-1 expression in endothelial cells","author":"Moers","year":"1997","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib58","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0008-6363(98)00331-9","article-title":"Chronic selective hypertriglyceridemia impairs endothelium-dependent vasodilatation in rats","volume":"42","author":"Kusterer","year":"1999","journal-title":"Cardiovasc Res J"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib59","doi-asserted-by":"crossref","first-page":"E53","DOI":"10.1161\/01.ATV.20.9.e53","article-title":"Role of macrophage-derived lipoprotein lipase in lipoprotein metabolism and atherosclerosis","volume":"20","author":"Van Eck","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib60","doi-asserted-by":"crossref","first-page":"7105","DOI":"10.1016\/S0021-9258(19)68930-1","article-title":"Secretion of lipoprotein lipase by macrophages in culture","volume":"256","author":"Khoo","year":"1981","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib61","doi-asserted-by":"crossref","first-page":"10143","DOI":"10.1073\/pnas.88.22.10143","article-title":"Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions","volume":"88","author":"Yl\u00e4-Herttuala","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib62","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1172\/JCI115747","article-title":"Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques","volume":"89","author":"O'Brien","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib63","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1161\/01.ATV.12.12.1458","article-title":"Regulation of lipoprotein lipase secretion in murine macrophages during foam cell formation in vitro. Effect of triglyceride-rich lipoproteins","volume":"12","author":"Sofer","year":"1992","journal-title":"Arterioscler Thromb"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib64","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1172\/JCI115595","article-title":"Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix","volume":"89","author":"Saxena","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib65","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0022-2275(20)37703-8","article-title":"Lipoprotein lipase enhances the interaction of low density lipoproteins with artery-derived extracellular matrix proteoglycans","volume":"34","author":"Edwards","year":"1993","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib66","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1016\/S0022-2275(20)37147-9","article-title":"Lipoprotein lipase enhances human monocyte adhesion to aortic endothelial cells","volume":"38","author":"Mamputu","year":"1997","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib67","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1006\/bbrc.2000.2747","article-title":"Regulated expression of endothelial cell-derived lipase","volume":"272","author":"Hirata","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib68","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0022-2275(20)30466-1","article-title":"Characterization of the lipolytic activity of endothelial lipase","volume":"43","author":"McCoy","year":"2002","journal-title":"J Lipid Res"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib69","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1161\/01.RES.0000064502.47539.6D","article-title":"Endothelial cells secrete triglyceride lipase and phospholipase activities in response to cytokines as a result of endothelial lipase","volume":"92","author":"Jin","year":"2003","journal-title":"Circ Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib70","doi-asserted-by":"crossref","first-page":"2876","DOI":"10.1002\/j.1460-2075.1995.tb07287.x","article-title":"Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli","volume":"14","author":"Traenckner","year":"1995","journal-title":"EMBO J"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib71","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1172\/JCI119636","article-title":"Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation","volume":"100","author":"Steinberg","year":"1997","journal-title":"J Clin Invest"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib72","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.2337\/diabetes.49.11.1939","article-title":"High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells","volume":"49","author":"Inoguchi","year":"2000","journal-title":"Diabetes"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib73","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1042\/BST0320994","article-title":"Triacylglycerol-rich lipoprotein\u2013gene interactions in endothelial cells","volume":"32","author":"Williams","year":"2004","journal-title":"Biochem Soc Trans"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib74","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0022-2275(20)37641-0","article-title":"Linoleic acid and TNF-alpha cross-amplify oxidative injury and dysfunction of endothelial cells","volume":"37","author":"Toborek","year":"1996","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib75","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0026-0495(98)90241-4","article-title":"Effect of linoleic acid on endothelial cell inflammatory mediators","volume":"47","author":"Young","year":"1998","journal-title":"Metabolism"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib76","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0021-9150(96)05968-0","article-title":"Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall","volume":"127","author":"Rus","year":"1996","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib77","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0021-9150(99)00463-3","article-title":"Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?","volume":"148","author":"Yudkin","year":"2000","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib78","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1161\/01.ATV.14.11.1829","article-title":"The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells","volume":"14","author":"De Caterina","year":"1994","journal-title":"Arterioscler Thromb"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib79","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/01.ATV.15.5.622","article-title":"Docosahexaenoic acid selectively attenuates induction of vascular cell adhesion molecule-1 and subsequent monocytic adhesion to human endothelial cells stimulated by tumor necrosis factor-alpha","volume":"15","author":"Weber","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib80","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1097\/00007890-199612150-00020","article-title":"Docosahexaenoic and eicosapentaenoic acids inhibit in vitro human lymphocyte\u2013endothelial adhesion","volume":"62","author":"Khalfoun","year":"1996","journal-title":"Transplantation"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib81","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1046\/j.1365-2362.1998.00336.x","article-title":"Effects of omega-3 fatty acids and\/or antioxidants on endothelial cell markers","volume":"28","author":"Seljeflot","year":"1998","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib82","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1161\/01.ATV.19.7.1681","article-title":"The effect of supplementation with omega-3 fatty acids on soluble markers of endothelial function in patients with coronary heart disease","volume":"19","author":"Johansen","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib83","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF01990956","article-title":"Biological activity of prostaglandin E3 with regard to oedema formation in mice","volume":"35","author":"Hawkes","year":"1992","journal-title":"Agents Actions"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib84","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/0006-291X(83)91572-3","article-title":"Human neutrophil chemotactic and degranulating activities of leukotriene B5 (LTB5) derived from eicosapentaenoic acid","volume":"117","author":"Goldman","year":"1983","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib85","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1093\/jn\/121.5.631","article-title":"Interaction between fish and vegetable oils in relation to rat leucocyte leukotriene production","volume":"121","author":"James","year":"1991","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib86","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1002\/1438-9312(200210)104:9\/10<698::AID-EJLT698>3.0.CO;2-A","article-title":"Mediterranean diet, olive oil and health","volume":"104","author":"Wahrburg","year":"2002","journal-title":"Eur J Lipid Sci Technol"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib87","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1093\/oxfordjournals.aje.a114480","article-title":"The diet and 15-year death rate in the Seven Countries Study","volume":"124","author":"Keys","year":"1986","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib88","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/S0140-6736(94)92580-1","article-title":"Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease","volume":"343","author":"de Lorgeril","year":"1994","journal-title":"Lancet"},{"issue":"26","key":"10.1016\/j.jnutbio.2005.11.007_bib89","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1056\/NEJMoa025039","article-title":"Adherence to a Mediterranean diet and survival in a Greek population","volume":"348","author":"Trichopoulou","year":"2003","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1016\/j.jnutbio.2005.11.007_bib90","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1001\/archinte.165.8.929","article-title":"Mediterranean diet and survival among patients with coronary heart disease in Greece","volume":"165","author":"Trichopoulou","year":"2005","journal-title":"Arch Intern Med"},{"issue":"26","key":"10.1016\/j.jnutbio.2005.11.007_bib91","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1056\/NEJMp030069","article-title":"The Mediterranean diet and mortality \u2014 olive oil and beyond","volume":"348","author":"Hu","year":"2003","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1016\/j.jnutbio.2005.11.007_bib92","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1161\/01.ATV.12.8.911","article-title":"Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials","volume":"12","author":"Mensink","year":"1992","journal-title":"Arterioscler Thromb"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib93","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1161\/01.ATV.15.11.1917","article-title":"Monounsaturated versus polyunsaturated dietary fat and serum lipids. A meta-analysis","volume":"15","author":"Gardner","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib94","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1093\/ajcn\/70.6.1009","article-title":"High-monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations","volume":"70","author":"Kris-Etherton","year":"1999","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib95","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/ajcn\/56.1.77","article-title":"Effect of dietary monounsaturated fatty acids on plasma lipoproteins and apolipoproteins in women","volume":"56","author":"Mata","year":"1992","journal-title":"Am J Clin Nutr"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib96","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1079\/BJN2003852","article-title":"Plasma lipid modifications in elderly people after administration of two virgin olive oils of the same variety (Olea europaea var. hojiblanca) with different triacylglycerol composition","volume":"89","author":"Perona","year":"2003","journal-title":"Br J Nutr"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib97","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.clnu.2004.02.004","article-title":"Virgin olive oil reduces blood pressure in hypertensive elderly subjects","volume":"23","author":"Perona","year":"2004","journal-title":"Clin Nutr"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib98","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.clnu.2003.11.005","article-title":"Sunflower oil does not protect against LDL oxidation as virgin olive oil does in patients with peripheral vascular disease","volume":"23","author":"Aguilera","year":"2004","journal-title":"Clin Nutr"},{"issue":"10 Suppl 1","key":"10.1016\/j.jnutbio.2005.11.007_bib99","first-page":"S73","article-title":"Arterial hypertension in Spain: the experience of the Spanish League","author":"Aranda","year":"1996","journal-title":"J Hum Hypertens"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib100","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2337\/diacare.12.2.94","article-title":"Persistence of hypertriglyceridemic effect of low-fat high-carbohydrate diets in NIDDM patients","volume":"12","author":"Coulston","year":"1989","journal-title":"Diabetes Care"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib101","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1001\/archinte.1993.00410120017003","article-title":"Does supplementation of diet with \u2018fish oil\u2019 reduce blood pressure? A meta-analysis of controlled clinical trials","volume":"153","author":"Appel","year":"1993","journal-title":"Arch Intern Med"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib102","first-page":"S453","article-title":"Hypotensive effects of eicosapentaenoic acid (EPA) and its influence on eicosanoid metabolism in spontaneously hypertensive rats","volume":"4","author":"Lam","year":"1986","journal-title":"J Hypertens Suppl"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib103","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0021-9150(02)00033-3","article-title":"Protective effect of dietary monounsaturated fat on arteriosclerosis: beyond cholesterol","volume":"163","author":"Perez-Jimenez","year":"2002","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib104","first-page":"147","article-title":"Monounsaturated fatty acids enriched diets lower plasma insulin levels and blood pressure in healthy young men","volume":"6","author":"Espino","year":"1996","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"9","key":"10.1016\/j.jnutbio.2005.11.007_bib105","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1046\/j.1365-2362.1997.1860735.x","article-title":"Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure","volume":"27","author":"Lahoz","year":"1997","journal-title":"Eur J Clin Invest"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib106","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1097\/00004872-199612000-00016","article-title":"Plasma lipids, erythrocyte membrane lipids and blood pressure of hypertensive women after ingestion of dietary oleic acid from two different sources","volume":"14","author":"Ruiz-Gutierrez","year":"1996","journal-title":"J Hypertens"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib107","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/ajcn\/80.4.1012","article-title":"Olive oil, the Mediterranean diet, and arterial blood pressure: the Greek European Prospective Investigation into Cancer and Nutrition (EPIC) Study","volume":"80","author":"Psaltopoulou","year":"2004","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib108","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/BF02535259","article-title":"Dietary N-6 and N-3 fatty acids and salt-induced hypertension in the borderline hypertensive rat","volume":"24","author":"Mills","year":"1989","journal-title":"Lipids"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib109","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/ajcn\/53.4.899","article-title":"Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins \u2014 the Jerusalem Nutrition Study: high MUFAs vs high PUFAs","volume":"53","author":"Berry","year":"1991","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib110","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1093\/ajcn\/54.4.701","article-title":"Feasibility of using an oleate-rich diet to reduce the susceptibility of low-density lipoprotein to oxidative modification in humans","volume":"54","author":"Reaven","year":"1991","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib111","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1161\/01.ATV.12.4.529","article-title":"Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoproteins to oxidative modification","volume":"12","author":"Bonanome","year":"1992","journal-title":"Arterioscler Thromb"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib112","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1161\/01.ATV.16.12.1465","article-title":"Effect of antioxidants alone and in combination with monounsaturated fatty acid-enriched diets on lipoprotein oxidation","volume":"16","author":"Reaven","year":"1996","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib113","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1093\/jn\/131.6.1758","article-title":"Low fat and high monounsaturated fat diets decrease human low density lipoprotein oxidative susceptibility in vitro","volume":"131","author":"Hargrove","year":"2001","journal-title":"J Nutr"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib114","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/sj.ejcn.1600566","article-title":"Monounsaturated oils do not all have the same effect on plasma cholesterol","volume":"52","author":"Truswell","year":"1998","journal-title":"Eur J Clin Nutr"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib115","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1007\/s000180050061","article-title":"Intake of olive oil can modulate the transbilayer movement of human erythrocyte membrane cholesterol","volume":"53","author":"Muriana","year":"1997","journal-title":"Cell Mol Life Sci"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib116","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0024-3205(99)00622-0","article-title":"Effect of two high-oleic oils on the liver lipid composition of spontaneously hypertensive rats","volume":"66","author":"Perona","year":"2000","journal-title":"Life Sci"},{"issue":"13","key":"10.1016\/j.jnutbio.2005.11.007_bib117","doi-asserted-by":"crossref","first-page":"4227","DOI":"10.1021\/jf0498923","article-title":"Virgin olive oil normalizes the altered triacylglycerol molecular species composition of adipose tissue in spontaneously hypertensive rats","volume":"52","author":"Perona","year":"2004","journal-title":"J Agric Food Chem"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib118","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.amjhyper.2004.11.012","article-title":"Triacylglycerol molecular species are depleted to different extents in the myocardium of spontaneously hypertensive rats fed two oleic acid-rich oils","volume":"18","author":"Perona","year":"2005","journal-title":"Am J Hypertens"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib119","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1079\/BJN2001397","article-title":"Effects of dietary oleic-rich oils (virgin olive and high-oleic-acid sunflower) on vascular reactivity in Wistar\u2013Kyoto and spontaneously hypertensive rats","volume":"86","author":"Herrera","year":"2001","journal-title":"Br J Nutr"},{"issue":"9","key":"10.1016\/j.jnutbio.2005.11.007_bib120","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/sj.ejcn.1600833","article-title":"Incorporation of dietary triacylglycerols from olive oil and high-oleic sunflower oil into VLDL triacylglycerols of hypertensive patients","volume":"53","author":"Ruiz-Gutierrez","year":"1999","journal-title":"Eur J Clin Nutr"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib121","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/jn\/128.3.570","article-title":"Composition of human VLDL triacylglycerols after ingestion of olive oil and high oleic sunflower oil","volume":"128","author":"Ruiz-Gutierrez","year":"1998","journal-title":"J Nutr"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib122","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/jn\/131.1.59","article-title":"The metabolic availability of dietary triacylglycerols from two high oleic oils during the postprandial period does not depend on the amount of oleic acid ingested by healthy men","volume":"131","author":"Abia","year":"2001","journal-title":"J Nutr"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib123","doi-asserted-by":"crossref","first-page":"5653","DOI":"10.1021\/jf010576n","article-title":"Triacylglycerol-rich lipoproteins interact with human vascular cells in a lipid-dependent fashion","volume":"49","author":"Pacheco","year":"2001","journal-title":"J Agric Food Chem"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib124","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1093\/jn\/134.12.3284","article-title":"The unsaponifiable fraction of virgin olive oil in chylomicrons from men improves the balance between vasoprotective and prothrombotic factors released by endothelial cells","volume":"134","author":"Perona","year":"2004","journal-title":"J Nutr"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib125","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S0022-2275(20)41427-0","article-title":"Effect of dietary oils on lipid peroxidation and on antioxidant parameters of rat plasma and lipoprotein fractions","volume":"33","author":"Scaccini","year":"1992","journal-title":"J Lipid Res"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib126","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000012741","article-title":"Comparison between extra virgin olive oil and oleic acid rich sunflower oil: effects on postprandial lipemia and LDL susceptibility to oxidation","volume":"42","author":"Nicolaiew","year":"1998","journal-title":"Ann Nutr Metab"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib127","series-title":"Recent research and development in nutrition","first-page":"173","article-title":"Beneficial effects of olive oil on health","author":"Ruiz-Guti\u00e9rrez","year":"2000"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib128","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF02638054","article-title":"The hydrocarbon fraction of virgin olive oil and changes resulting from refining","volume":"71","author":"Lanz\u00f3n","year":"1994","journal-title":"J Am Oil Chem Soc"},{"issue":"7","key":"10.1016\/j.jnutbio.2005.11.007_bib129","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1021\/jf950571o","article-title":"Differences in hydrocarbons of virgin olive oils obtained from several olive varieties","volume":"44","author":"Ginda","year":"1993","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib130","first-page":"519","article-title":"Chemical composition of olive oil and its variations induced by refining","volume":"59","author":"Tiscornia","year":"1982","journal-title":"Riv Ital Sostanze Grasse"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib131","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/BF02540514","article-title":"Identification and classification of olive oils by high-resolution C-13 nuclear-magnetic-resonance","volume":"71","author":"Zamora","year":"1994","journal-title":"J Am Oil Chem Soc"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib132","first-page":"966","article-title":"Polyphenols in olive oils","volume":"58","author":"Gutfinger","year":"1981","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib133","first-page":"21","article-title":"Les polyph\u00e9noles de l'huile d'olive et leur influence sur les caract\u00e9ristiques de l\u2019huile","volume":"25","author":"Vazquez-Roncero","year":"1978","journal-title":"Rev Fr Corps Gras"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib134","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0308-8146(92)90025-W","article-title":"Phenolic compounds and stability of virgin olive oil: Part I","volume":"45","author":"Tsimidou","year":"1992","journal-title":"Food Chem"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib135","series-title":"Olive oil chemistry and technology","first-page":"115","author":"Boskov","year":"1996"},{"issue":"5 Pt 1","key":"10.1016\/j.jnutbio.2005.11.007_bib136","first-page":"142","article-title":"The effect of minor constituents of olive oil on cardiovascular disease: new findings","volume":"56","author":"Visioli","year":"1998","journal-title":"Nutr Rev"},{"issue":"2\u20133","key":"10.1016\/j.jnutbio.2005.11.007_bib137","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0014-5793(00)01216-3","article-title":"Olive oil phenolics are dose-dependently absorbed in humans","volume":"468","author":"Visioli","year":"2000","journal-title":"FEBS Lett"},{"issue":"9","key":"10.1016\/j.jnutbio.2005.11.007_bib138","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1093\/jn\/134.9.2314","article-title":"Olive oils high in phenolic compounds modulate oxidative\/antioxidative status in men","volume":"134","author":"Weinbrenner","year":"2004","journal-title":"J Nutr"},{"issue":"5\u20136","key":"10.1016\/j.jnutbio.2005.11.007_bib139","first-page":"207","article-title":"Bioavailability of phenolic compounds from olive oil and oxidative\/antioxidant status at postprandial state in healthy humans","volume":"30","author":"Weinbrenner","year":"2004","journal-title":"Drugs Exp Clin Res"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib140","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00394-004-0504-0","article-title":"Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients","volume":"44","author":"Visioli","year":"2005","journal-title":"Eur J Nutr"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib141","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/qjmed\/93.2.85","article-title":"Diabetes and the Mediterranean diet: a beneficial effect of oleic acid on insulin sensitivity, adipocyte glucose transport and endothelium-dependent vasoreactivity","volume":"93","author":"Ryan","year":"2000","journal-title":"QJM"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib142","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.7326\/0003-4819-134-12-200106190-00011","article-title":"Mediterranean and low-fat diets improve endothelial function in hypercholesterolemic men","volume":"134","author":"Fuentes","year":"2001","journal-title":"Ann Intern Med"},{"issue":"13","key":"10.1016\/j.jnutbio.2005.11.007_bib143","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1161\/01.CIR.0000124477.91474.FF","article-title":"A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial","volume":"109","author":"Ros","year":"2004","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib144","doi-asserted-by":"crossref","first-page":"E19","DOI":"10.1016\/S0002-8703(03)00078-4","article-title":"Effect of dietary intervention and lipid-lowering treatment on brachial vasoreactivity in patients with ischemic heart disease and hypercholesterolemia","volume":"145","author":"Sondergaard","year":"2003","journal-title":"Am Heart J"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib145","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1001\/jama.292.12.1440","article-title":"Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial","volume":"292","author":"Esposito","year":"2004","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.jnutbio.2005.11.007_bib146","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1053\/meta.2000.7736","article-title":"Fatty acid-mediated activation of vascular endothelial cells","volume":"49","author":"Hennig","year":"2000","journal-title":"Metabolism"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib147","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1161\/01.ATV.19.2.220","article-title":"Oleic acid inhibits endothelial activation: direct vascular antiatherogenic mechanism of a nutritional component in the Mediterranean diet","volume":"19","author":"Carluccio","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib148","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1161\/01.ATV.19.1.122","article-title":"LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress","volume":"19","author":"Tsimikas","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib149","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/S0022-2275(20)32548-7","article-title":"Liposomes enriched in oleic acid are less susceptible to oxidation and have less proinflammatory activity when exposed to oxidizing conditions","volume":"39","author":"Lee","year":"1998","journal-title":"J Lipid Res"},{"issue":"8","key":"10.1016\/j.jnutbio.2005.11.007_bib150","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1301\/nr.2003.aug.272-279","article-title":"Mechanisms of action of dietary fatty acids in regulating the activation of vascular endothelial cells during atherogenesis","volume":"61","author":"Christon","year":"2003","journal-title":"Nutr Rev"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib151","first-page":"660","article-title":"Endotoxin stimulates gene expression of ROS eliminating pathways in rat hepatic endothelial and Kupffer cells","volume":"270","author":"Spolarics","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib152","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev.iy.12.040194.001041","article-title":"Function and activation of NF-kB in the immune system","volume":"12","author":"Baeuerle","year":"1994","journal-title":"Annu Rev Immunol"},{"issue":"2\u20133","key":"10.1016\/j.jnutbio.2005.11.007_bib153","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1054\/plef.2002.0386","article-title":"Mechanisms for reduction of endothelial activation by oleate: inhibition of nuclear factor-kappaB through antioxidant effects","volume":"67","author":"Massaro","year":"2002","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib154","first-page":"507","article-title":"Direct vascular antiatherogenic effects of oleic acid: a clue to the cardioprotective effects of the Mediterranean diet","volume":"44","author":"Massaro","year":"1999","journal-title":"Cardiologia"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib155","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/ajcn\/75.1.119","article-title":"Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells","volume":"75","author":"Toborek","year":"2002","journal-title":"Am J Clin Nutr"},{"issue":"34 Suppl","key":"10.1016\/j.jnutbio.2005.11.007_bib156","first-page":"S213","article-title":"The double bond in unsaturated fatty acids is the necessary and sufficient requirement for the inhibition of expression of endothelial leukocyte adhesion molecules through interference with nuclear factor-kappaB activation","author":"Massaro","year":"1999","journal-title":"Lipids"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib157","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0092-8674(95)90506-5","article-title":"NF-kB: a lesson in family values","volume":"80","author":"Thanos","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib158","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1172\/JCI116778","article-title":"Vascular cell adhesion molecule (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells","volume":"92","author":"Marui","year":"1993","journal-title":"J Clin Invest"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib159","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3109\/01902149709039235","article-title":"Oleic acid reduces oxidant stress in cultured pulmonary artery endothelial cells","volume":"23","author":"Hart","year":"1997","journal-title":"Exp Lung Res"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib160","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0952-3278(97)90582-2","article-title":"Endothelial cell monolayer dysfunction caused by oxidized low density lipoprotein: attenuation by oleic acid","volume":"56","author":"Karman","year":"1997","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib161","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/jcp.1041560105","article-title":"Oleic acid supplementation reduces oxidant-mediated dysfunction of cultured porcine pulmonary artery endothelial cells","volume":"156","author":"Hart","year":"1993","journal-title":"J Cell Physiol"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib162","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1055\/s-0037-1613207","article-title":"Quenching of intracellular ROS generation as a mechanism for oleate-induced reduction of endothelial activation and early atherogenesis","volume":"88","author":"Massaro","year":"2002","journal-title":"Thromb Haemost"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib163","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1053\/meta.2000.17719","article-title":"Linoleic acid and oleic acid increase the endothelin-1 binding and action in cultured rat aortic smooth muscle cells","volume":"49","author":"Kwok","year":"2000","journal-title":"Metabolism"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib164","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.2741\/1300","article-title":"Direct effects of long-chain non-esterified fatty acids on vascular cells and their relevance to macrovascular complications of diabetes","volume":"9","author":"Oram","year":"2004","journal-title":"Front Biosci"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib165","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/S0955-2863(02)00229-2","article-title":"Major phenolic compounds in olive oil: metabolism and health effects","volume":"13","author":"Tuck","year":"2002","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib166","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0033-0620(05)80003-9","article-title":"Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action","volume":"38","author":"Keaney","year":"1995","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib167","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1161\/01.RES.87.10.840","article-title":"Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress","volume":"87","author":"Cai","year":"2000","journal-title":"Circ Res"},{"issue":"22","key":"10.1016\/j.jnutbio.2005.11.007_bib168","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1161\/hc4601.099485","article-title":"Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease","volume":"104","author":"Heitzer","year":"2001","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib169","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1161\/01.CIR.95.12.2617","article-title":"Vitamin C improves endothelium-dependent vasodilation in forearm resistance vessels of humans with hypercholesterolemia","volume":"95","author":"Ting","year":"1997","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib170","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1161\/01.CIR.93.6.1107","article-title":"Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease","volume":"93","author":"Levine","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib171","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1161\/01.CIR.94.1.6","article-title":"Antioxidant vitamin C improves endothelial dysfunction in chronic smokers","volume":"94","author":"Heitzer","year":"1996","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.jnutbio.2005.11.007_bib172","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1161\/01.RES.83.9.916","article-title":"Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations","volume":"83","author":"Jackson","year":"1998","journal-title":"Circ Res"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib173","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0378-5173(98)00018-0","article-title":"In vitro evaluation of the antioxidant activity and biomembrane interaction of the plant phenols oleuropein and hydroxy-tyrosol","volume":"166","author":"Saija","year":"1998","journal-title":"Int J Pharm"},{"issue":"5","key":"10.1016\/j.jnutbio.2005.11.007_bib174","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1021\/jf000537w","article-title":"Antioxidant activity of hydroxytyrosol acetate compared with that of other olive oil polyphenols","volume":"49","author":"Gordon","year":"2001","journal-title":"J Agric Food Chem"},{"issue":"7","key":"10.1016\/j.jnutbio.2005.11.007_bib175","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1021\/jf001342r","article-title":"Antioxidant activity of the main bioactive derivatives from oleuropein hydrolysis by hyperthermophilic beta-glycosidase","volume":"49","author":"Briante","year":"2001","journal-title":"J Agric Food Chem"},{"issue":"8","key":"10.1016\/j.jnutbio.2005.11.007_bib176","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1021\/jf011264n","article-title":"Structural characterization of the metabolites of hydroxytyrosol, the principal phenolic component in olive oil, in rats","volume":"50","author":"Tuck","year":"2002","journal-title":"J Agric Food Chem"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib177","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1006\/bbrc.1998.8735","article-title":"Free radical-scavenging properties of olive oil polyphenols","volume":"247","author":"Visioli","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib178","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0021-9150(01)00561-5","article-title":"Effect of meals rich in heated olive and safflower oils on oxidation of postprandial serum in healthy men","volume":"160","author":"Sutherland","year":"2002","journal-title":"Atherosclerosis"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib179","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0024-3205(97)01150-8","article-title":"Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages","volume":"62","author":"Visioli","year":"1998","journal-title":"Life Sci"},{"issue":"5 Pt 1","key":"10.1016\/j.jnutbio.2005.11.007_bib180","doi-asserted-by":"crossref","first-page":"C1424","DOI":"10.1152\/ajpcell.1996.271.5.C1424","article-title":"Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly","volume":"271","author":"Beckman","year":"1996","journal-title":"Am J Physiol"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib181","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0006-2952(98)00320-7","article-title":"Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil","volume":"57","author":"de la Puerta","year":"1999","journal-title":"Biochem Pharmacol"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib182","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0049-3848(95)00043-7","article-title":"Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil","volume":"78","author":"Petroni","year":"1995","journal-title":"Thromb Res"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib183","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0049-3848(97)00133-3","article-title":"Inhibition of leukocyte leukotriene B4 production by an olive oil-derived phenol identified by mass-spectrometry","volume":"87","author":"Petroni","year":"1997","journal-title":"Thromb Res"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib184","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1271\/bbb.61.347","article-title":"Inhibition of arachidonate lipoxygenase activities by 2-(3,4-dihydroxyphenyl)ethanol, a phenolic compound from olives","volume":"61","author":"Kohyama","year":"1997","journal-title":"Biosci Biotechnol Biochem"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib185","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000423575","article-title":"A phenolic antioxidant extracted from olive oil inhibits platelet aggregation and arachidonic acid metabolism in vitro","volume":"75","author":"Petroni","year":"1994","journal-title":"World Rev Nutr Diet"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib186","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.nut.2004.06.031","article-title":"Differential anti-inflammatory effects of phenolic compounds from extra virgin olive oil identified in human whole blood cultures","volume":"21","author":"Miles","year":"2005","journal-title":"Nutrition"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib187","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/01.ATV.0000062884.69432.A0","article-title":"Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals","volume":"23","author":"Carluccio","year":"2003","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"8","key":"10.1016\/j.jnutbio.2005.11.007_bib188","doi-asserted-by":"crossref","first-page":"4616","DOI":"10.1074\/jbc.273.8.4616","article-title":"Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-alpha","volume":"273","author":"Ahmad","year":"1998","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib189","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1024\/0300-9831.75.1.61","article-title":"Antioxidant and anti-atherogenic activities of olive oil phenolics","volume":"75","author":"Turner","year":"2005","journal-title":"Int J Vitam Nutr Res"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib190","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1124\/mol.64.2.211","article-title":"Inhibition of nuclear factor kappaB by phenolic antioxidants: interplay between antioxidant signaling and inflammatory cytokine expression","volume":"64","author":"Ma","year":"2003","journal-title":"Mol Pharmacol"},{"issue":"1\u20133","key":"10.1016\/j.jnutbio.2005.11.007_bib191","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0014-5793(02)02706-0","article-title":"Non-antioxidant molecular functions of alpha-tocopherol (vitamin E)","volume":"519","author":"Azzi","year":"2002","journal-title":"FEBS Lett"},{"issue":"9\u201310","key":"10.1016\/j.jnutbio.2005.11.007_bib192","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1515\/znc-2000-9-1023","article-title":"Effect of minor components of virgin olive oil on topical antiinflammatory assays","volume":"55","author":"de la Puerta","year":"2000","journal-title":"Z Naturforsch [C]"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib193","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1079\/BJN20041231","article-title":"Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in \u2018orujo\u2019 olive oil, on rat aorta","volume":"92","author":"Rodriguez-Rodriguez","year":"2004","journal-title":"Br J Nutr"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib194","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0899-9007(01)00732-8","article-title":"Dietary oils high in oleic acid but with different unsaponifiable fraction contents have different effects in fatty acid composition and peroxidation in rabbit LDL","volume":"18","author":"Ochoa","year":"2002","journal-title":"Nutrition"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib195","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0098-2997(03)00028-1","article-title":"The role of alpha-tocopherol in preventing disease: from epidemiology to molecular events","volume":"24","author":"Azzi","year":"2003","journal-title":"Mol Aspects Med"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib196","first-page":"30","article-title":"Regulation of gene and protein expression by vitamin E","volume":"36","author":"Azzi","year":"2002","journal-title":"Free Radic Res"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib197","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1161\/01.ATV.15.2.190","article-title":"The effect of alpha-tocopherol supplementation on LDL oxidation. A dose\u2013response study","volume":"15","author":"Jialal","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib198","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1161\/01.ATV.15.3.325","article-title":"Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women","volume":"15","author":"Princen","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"10","key":"10.1016\/j.jnutbio.2005.11.007_bib199","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1161\/01.ATV.17.10.2273","article-title":"Dose\u2013response comparison of RRR-\u03b1-tocopherol and all-racemic alpha-tocopherol on LDL oxidation","volume":"17","author":"Devaraj","year":"1997","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"1\u20133","key":"10.1016\/j.jnutbio.2005.11.007_bib200","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0009-8981(91)90217-Z","article-title":"Predisposition to LDL oxidation during copper-catalyzed oxidative modification and its relation to alpha-tocopherol content in humans","volume":"204","author":"Cominacini","year":"1991","journal-title":"Clin Chim Acta"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib201","first-page":"52","article-title":"Antioxidants and atherosclerosis: a molecular perspective","volume":"3","author":"Offermann","year":"1994","journal-title":"Heart Dis Stroke"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib202","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1161\/01.ATV.17.3.429","article-title":"Vitamin E inhibits low-density lipoprotein-induced adhesion of monocytes to human aortic endothelial cells in vitro","volume":"17","author":"Martin","year":"1997","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib203","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1006\/bbrc.2000.3197","article-title":"Selective inhibition by alpha-tocopherol of vascular cell adhesion molecule-1 expression in human vascular endothelial cells","volume":"274","author":"Zapolska-Downar","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib204","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1172\/JCI117374","article-title":"\u03b1-Tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells","volume":"94","author":"Faruqi","year":"1994","journal-title":"J Clin Invest"},{"issue":"1\u20132","key":"10.1016\/j.jnutbio.2005.11.007_bib205","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/biof.5520070103","article-title":"\u03b1-Tocopherol protects against expression of adhesion molecules on neutrophils and endothelial cells","volume":"7","author":"Yoshikawa","year":"1998","journal-title":"Biofactors"},{"issue":"2\u20133","key":"10.1016\/j.jnutbio.2005.11.007_bib206","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0021-9150(91)90222-O","article-title":"Inhibition of IL-1 beta expression in THP-1 cells by probucol and tocopherol","volume":"86","author":"Akeson","year":"1991","journal-title":"Atherosclerosis"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib207","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0090-6980(80)80003-7","article-title":"Generation of prostacyclin-like substance and lipid peroxidation in vitamin E-deficient rats","volume":"19","author":"Okuma","year":"1980","journal-title":"Prostaglandins"},{"issue":"11","key":"10.1016\/j.jnutbio.2005.11.007_bib208","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1093\/ajcn\/34.11.2341","article-title":"Decreased prostacyclin synthesis in vitamin E-deficient rabbit aorta","volume":"34","author":"Chan","year":"1981","journal-title":"Am J Clin Nutr"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib209","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1055\/s-0038-1646354","article-title":"Vitamin E binds to specific binding sites and enhances prostacyclin production by cultured aortic endothelial cells","volume":"68","author":"Kunisaki","year":"1992","journal-title":"Thromb Haemost"},{"issue":"6","key":"10.1016\/j.jnutbio.2005.11.007_bib210","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0026-0495(92)90053-D","article-title":"Vitamin E restores reduced prostacyclin synthesis in aortic endothelial cells cultured with a high concentration of glucose","volume":"41","author":"Kunisaki","year":"1992","journal-title":"Metabolism"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib211","doi-asserted-by":"crossref","first-page":"389S","DOI":"10.1093\/jn\/131.2.389S","article-title":"The effect of alpha-tocopherol on monocyte proatherogenic activity","volume":"131","author":"Jialal","year":"2001","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib212","doi-asserted-by":"crossref","first-page":"382S","DOI":"10.1093\/jn\/131.2.382S","article-title":"Vitamin E and macrophage cyclooxygenase regulation in the aged","volume":"131","author":"Wu","year":"2001","journal-title":"J Nutr"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib213","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0047-6374(86)90034-5","article-title":"Vitamin E supplementation suppresses prostaglandin E1(2) synthesis and enhances the immune response of aged mice","volume":"34","author":"Meydani","year":"1986","journal-title":"Mech Ageing Dev"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib214","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1093\/jn\/120.1.112","article-title":"Dietary energy restriction decreases ex vivo spleen prostaglandin E2 synthesis in Emory mice","volume":"120","author":"Meydani","year":"1990","journal-title":"J Nutr"},{"issue":"8","key":"10.1016\/j.jnutbio.2005.11.007_bib215","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1093\/jn\/122.8.1627","article-title":"Lung eicosanoid synthesis is affected by age, dietary fat and vitamin E","volume":"122","author":"Meydani","year":"1992","journal-title":"J Nutr"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib216","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1159\/000085465","article-title":"Peroxynitrite modulates release of inflammatory mediators from guinea pig lung mast cells activated by antigen\u2013antibody reaction","volume":"137","author":"Kim","year":"2005","journal-title":"Int Arch Allergy Immunol"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib217","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/jn\/120.4.331","article-title":"Effect of vitamin E on linoleic acid-mediated induction of peroxisomal enzymes in cultured porcine endothelial cells","volume":"120","author":"Hennig","year":"1990","journal-title":"J Nutr"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib218","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/00005344-200009000-00003","article-title":"Effects of alpha-tocopherol on ox-LDL-mediated degradation of IkappaB and apoptosis in cultured human coronary artery endothelial cells","volume":"36","author":"Li","year":"2000","journal-title":"J Cardiovasc Pharmacol"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib219","first-page":"93","article-title":"The effect of alpha-tocopherol and beta-tocopherol on proliferation, protein kinase C activity and gene expression in different cell lines","volume":"41","author":"Fazzio","year":"1997","journal-title":"Biochem Mol Biol Int"},{"issue":"12","key":"10.1016\/j.jnutbio.2005.11.007_bib220","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/S0891-5849(01)00541-X","article-title":"Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins","volume":"30","author":"Breyer","year":"2001","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib221","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1161\/01.CIR.91.7.1914","article-title":"Aspirin inhibits NF-\u03baB mobilization and monocyte adhesion in stimulated human endothelial cells","volume":"91","author":"Weber","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib222","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0014-5793(99)00141-6","article-title":"Tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation and both lysosomal and mitochondrial destabilisation","volume":"445","author":"Neuzil","year":"1999","journal-title":"FEBS Lett"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib223","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1054\/bjoc.2000.1559","article-title":"Selective cancer cell killing by \u03b1-tocopheryl succinate","volume":"84","author":"Neuzil","year":"2001","journal-title":"Br J Cancer"},{"issue":"7","key":"10.1016\/j.jnutbio.2005.11.007_bib224","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1073\/pnas.94.7.3217","article-title":"Gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications","volume":"94","author":"Christen","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.1016\/j.jnutbio.2005.11.007_bib225","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1139\/y97-011","article-title":"Dietary phytosterols as cholesterol-lowering agents in humans","volume":"75","author":"Jones","year":"1997","journal-title":"Can J Physiol Pharmacol"},{"issue":"10","key":"10.1016\/j.jnutbio.2005.11.007_bib226","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0955-2863(01)00175-9","article-title":"Injected phytosterols\/stanols suppress plasma cholesterol levels in hamsters","volume":"12","author":"Vanstone","year":"2001","journal-title":"J Nutr Biochem"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib227","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0261-5614(03)00060-8","article-title":"Potential uses and benefits of phytosterols in diet: present situation and future directions","volume":"22","author":"Quilez","year":"2003","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib228","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.atherosclerosis.2005.01.031","article-title":"Margarine phytosterols decrease the secretion of atherogenic lipoproteins from HepG2 liver and Caco2 intestinal cells","volume":"182","author":"Ho","year":"2005","journal-title":"Atherosclerosis"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib229","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1023\/A:1025155002348","article-title":"Plant sterols lower LDL cholesterol without improving endothelial function in prepubertal children with familial hypercholesterolaemia","volume":"26","author":"de Jongh","year":"2003","journal-title":"J Inherit Metab Dis"},{"issue":"9","key":"10.1016\/j.jnutbio.2005.11.007_bib230","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/S0891-5849(03)00465-9","article-title":"Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7","volume":"35","author":"Moreno","year":"2003","journal-title":"Free Radic Biol Med"},{"issue":"4","key":"10.1016\/j.jnutbio.2005.11.007_bib231","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3989\/gya.1997.v48.i4.791","article-title":"Determination of sterols and triterpenic dialcohols in olive oils using HPLC separation and GC analysis. Standardization of the analytical method","volume":"48","author":"Cert","year":"1997","journal-title":"Grasas Aceites"},{"issue":"2","key":"10.1016\/j.jnutbio.2005.11.007_bib232","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0378-8741(95)90032-2","article-title":"Pharmacology of oleanolic acid and ursolic acid","volume":"49","author":"Liu","year":"1995","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.jnutbio.2005.11.007_bib233","unstructured":"Herrera MD, Rodriguez-Rodriguez R, Ruiz-Gutierrez V. Functional properties of pentacyclic triterpenes contained in \u201corujo\u201d olive oil. Curr Nutr Food Sci [in press]."},{"issue":"1","key":"10.1016\/j.jnutbio.2005.11.007_bib234","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/0005-2760(92)90157-Q","article-title":"Inhibition of lipoxygenase activity and HL60 leukemic cell proliferation by ursolic acid isolated from heather flowers (Calluna vulgaris)","volume":"1125","author":"Simon","year":"1992","journal-title":"Biochim Biophys Acta"},{"issue":"10","key":"10.1016\/j.jnutbio.2005.11.007_bib235","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1021\/np980088i","article-title":"Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis","volume":"61","author":"Ringbom","year":"1998","journal-title":"J Nat Prod"},{"issue":"7","key":"10.1016\/j.jnutbio.2005.11.007_bib236","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1248\/cpb.52.858","article-title":"The inhibition of superoxide anion generation by neutrophils from Viscum articulactum","volume":"52","author":"Leu","year":"2004","journal-title":"Chem Pharm Bull (Tokyo)"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286305002901?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286305002901?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T14:56:09Z","timestamp":1760626569000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286305002901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7]]},"references-count":236,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["S0955286305002901"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2005.11.007","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2006,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of virgin olive oil components in the modulation of endothelial function","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2005.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}